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Jurnal Ilmiah Farmasi
ISSN : 16938666     EISSN : -     DOI : -
Core Subject : Health,
JIF merupakan jurnal yang dikelola oleh Prodi Farmasi Universitas Islam Indonesia, dan diterbitkan dua kali dalam setahun. Jurnal ini dirancang sebagai sarana publikasi penelitian yang mencakup secara rinci sejumlah topik dalam bidang farmasi yang berkaitan dengan farmasi sains dan teknologi serta klinik dan komunitas. Jurnal ini menyediakan sebuah forum sebagai sarana pertukaran gagasan dan dan informasi antar peneliti, akademisi dan praktisi sehingga diharapkan mampu mendukung dan menginisiasi berbagai penelitian terkini yang terkait dengan ilmu kefarmasian. Hasil penelitian yang disajikan dalam jurnal ini diharapkan dapat memberikan kontribusi bagi perkembangan ilmu di bidang farmasi dan kesehatan.
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Articles 7 Documents
Search results for , issue " Vol 2, No 2 (2005)" : 7 Documents clear
PERBANDINGAN EFEKTIVITAS TRAGAKAN DAN PVP SEBAGAI PENGIKAT TERHADAP SIFAT FISIK TABLET HISAP EKSTRAK JAHE (Zingiber officinale Roxb.) Wintari Taurina; Melinda Dewi M; Yandi Syukri; Asih Triastuti
Jurnal Ilmiah Farmasi Vol 2, No 2 (2005)
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ABSTRACTGinger (Zingiber Officinale Roxb) is a traditional plants usually used to relieve pain, rheumatism,and neutralize poison. The aim of this study was to get the optimum concentration of tragacanthand PVP as a binding agent in ginger lozenges formulation. The components from ginger wereextracted using percolation with ethanol 70% and then evaporated using rotary evaporator.Lozenges were made in three formulas ; formula 1 (5%), 2 (7,5%), 3 (10%) of tragacanth and PVPusing wet granulation method. Granules and tablets were tested for its physical properties, andanalyzed using Pearson correlation. The result showed that, all of three formulas were good,comply with a regulation of physical properties and disolution time in the mouth. Variation oftragacanth and PVP concentration affected physical properties of tablets. It showed that the greaterconcentration of tragacanth and PVP, the larger the hardness and the longer the disolution time oftablets. The third formula (tragacanth 10% b/v) gave an optimum physical properties and solubletime of tablets, with weight variety deviation 0,98%, hardness 10,18 kg, friability 0.11% anddisolution time 11.50 minutes. The three formulas were received by respondens withprerequirement of improving sweetness, repairing form and the color of tablets.Key words :Ginger lozenges, tragacanth, PVP, wet granulation method.
AKTIVITAS ANTHELMINTIKA EKSTRAK ETANOL DAN EKSTRAK KLOROFORM RIMPANG BENGLE (Zingiber purpureum Roxb.) TERHADAP CACING Ascaridia galli Schrank SECARA IN VITRO BESERTA PROFIL KROMATOGRAFI LAPIS TIPIS Intan Permata Dewi; Wiharni Wiharni; C.J. Soegihardjo; Endang Darmawan
Jurnal Ilmiah Farmasi Vol 2, No 2 (2005)
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ABSTRACTPurple ginger (Zingiber Purpureum Roxb.) could be use as therapy for ascariasis. Theanthelmintic activity test by in vitro has been tested to get the validity of the effect. The maincomponents of the test is powder of purple ginger rhizoma which had been extracted bypercolation method with ethanol and maseration method with kloroform. Anthelmintic test had beendone by immersion method. The Ascaridia galli Schrank was soak in natrium chloride 0,9 %,pyrantel 0,125 %, extract ethanol 0,702 %, 1,404 %, 2,808 %, 5,616 % and exstract kloroform0,644 %, 1,288 %, 2,576 %, 5,152 %. From the test it could be concluded that the extract has theanthelmintic effect. The result evolution had been done by one way ANOVA method (P
SINTESIS DIASETIL GAMAVUTON-0 DENGAN MENGGUNAKAN ASETIL KLORIDA SEBAGAI ACYLATING AGENT Ridho Nugroho Zendrato; Supardjan Amir Margono
Jurnal Ilmiah Farmasi Vol 2, No 2 (2005)
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ABSTRACTGamavuton-0 is a curcumin-like compound, which is more stable than curcumin and stillhas an antioxidant property. The objective of synthesis of diacetyl gamavuton-0 (diAcGVT-0) is toyield the product that is more lipophile than GVT-0. Synthesis of diAcGVT-0 has been done byreacting GVT-0 with acetyl chloride as an acylating agent and tertiary amines as primary bases.DiAcGVT-0 was formed as the major product of synthesis and the product was not pure. Structureelucidation using UV-Vis,1H-NMR and MS spectra showed that the main product was diAcGVT-0.Key words : diacetyl gamavuton-0, acetyl chloride, acylating agent, lipophile
PENGARUH TIPE BASIS SALEP TERHADAP AKTIVITAS ANTIFUNGI DARI MINYAK ATSIRI KULIT KAYU MANIS CINA (Cinnamomum cassia Nees ex Bl.) PADA PENGHAMBATAN PERTUMBUHAN Candida albicans C.J. Soegihardjo; Siti Zahliyatul M; Nur Widya Astuti
Jurnal Ilmiah Farmasi Vol 2, No 2 (2005)
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ABSTRACTCinnamomum cassia Nees ex Bl. is known in the society as Chinese cinnamon. One ofthe uses of Chinese cinnamon is as a fungicide because of its volatile oil contents. The purpose ofthis research was to find out the base type effect of oil base, emulsion base, water soluble basetoward fungicide activity of Chinese cinnamon barks volatile oil on Candida albicans growthinhibition. The fungicide activity test of Chinese cinnamon barks volatile oil in the three base typeusing diffusion methods (agar plate) was done by measuring the diameter of inhibited area towardCandida albicans growth. The inhibited area diameter result was analyzed with one way anova testand continued with Tukey test at 95% confidential level. The obtained result showed that the threebase type was significantly different toward the fungicide activity of chinese cinnamon barks volatileoil. The largest inhibited area (from largest to the lowest) was water soluble base, emulsion base,and oil base.Keywords : minyak cassia, basis salep, Candida albicans
PREVALENSI VIRURIA SITOMEGALOVIRUS PADA POPULASI ORANG DEWASA NORMAL Dita Ria Selvyana; Praseno Praseno; Ning Rintiswati
Jurnal Ilmiah Farmasi Vol 2, No 2 (2005)
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ABSTRACTThe aim of this study was to get cytomegalovirus viruria prevalence data in healthy adultpopulation. Urine samples were obtained from healthy individuals. Preparation of sample and sera(polyclonal antibody) were performed by standard method., and detection of cytomegalovirusantigen in urine sediment were done by Indirect Immunofluorescence Antibodi Technique (IFAT).The results were analyzed with chi square pearson. From 341 healthy individuals (16 ♀ and 125 ♂)age between 18 to 61 years. Cytomegalovirys viruria were found in 5 (3, 55%) of subjects. In groupof subjects less than 30 years of age, cytomegalovirus viruria were found in 3,82% subject whereasin group of subjects more than 30 years of age, cytomegalovirus viruria was not found; chi squarepearson statistic analysis did not show significant difference between two groups (p = 0,529). Ingroup of women, cytomegalovirus viruria were found in 6,25% subjects whereas in group of men,cytomegalovirus viruria were found in 3,2% subjects; chi square pearson statistic analysis did notshow significant difference between two groups (p = 0,535). Cytomegalovirus viruria prevalenceamong healthy adult population studied was relatively low (3,55%).Key words: Cytomegalovirus, viruria, prevalence, latent infection, Indirect ImmunofluorescenceAntibodi Technique (IFAT)
ANALISIS LOG LINEAR TERHADAP FAKTOR-FAKTOR RESIKO CARCINOMA SERVIX UTERI DI RS BETHESDA YOGYAKARTA TAHUN 2002-2004 Edy Wibowo; Ade Yayu Ratna Inten
Jurnal Ilmiah Farmasi Vol 2, No 2 (2005)
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ABSTRACTThis research was done at Yogyakarta Bethesda hospital Jend. Sudirman, as a mean to knowthe association among risk factors at disease of Carcinoma servix uteri. This study used secondarydata from medical records and conducted with retrospektif method. The subjects in this researchwere patient of Carcinoma servix uteri at Bethesda hospital from 2002-2004. From the medicalrecords, researcher used three variables, they were age of patient, children amount and age whenthe patient first married. Statistical analysis that used was Log Linear analysis with BackwardElimination method with level of signifikansi equal to 0.15. From the analysis result can beconcluded that there were interaction between children amount, age of patient and age when thepatient first married to the prevalence of carcinoma servix uteri. The woman with children amountmore than 5 people, above age 50 year and also age of first married less than 20 year will have thehighest possibility to have carcinoma servix uteri.Key words : carcinoma servix uteri, risk factor and log linear analysis.
IDENTIFIKASI DAN PENENTUAN KONSENTRASI ION LOGAM Cr, Fe, Cu, Zn, Cd dan Pb PADA DEBU JALANAN DI SEKITAR KAWASAN MALIOBORO YOGYAKARTA Allwar Allwar
Jurnal Ilmiah Farmasi Vol 2, No 2 (2005)
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ABSTRACTIdentification and determination of heavy metal ions Cr, Fe, Cu, Zn, Cd and Pb on the duststreet around Malioboro area have been done. Malioboro area is one of the shopping centre andpedestrian tourism place in Yogyakarta that is the most crowded area. In summer season,Malioboro was not pleasant to visit caused by dry and hot climate, crowded and smell of exhaustedautomobile. These reason have been used to select Malioboro as a place for collecting dustsample. The dust has been obtained from five different locations such as location A station Tugu,location B Mall Matahari, location C governor office, location D pasar Bringharjo and location Ecross section of pos office. The dust sample was analyzed to identify and determine its metal ionscontain Cr, Fe, Cu, Zn, Cd and Pb using Atomic Absorption Spectrophotometry. The result of thisexperiment show that the highest concentration of ion metals at each location are Cu 656,75μg/gat location A , Fe 548,16μg/g at location B, Fe 420,16μg/g at location C, Pb 729,16μg/g at locationD and Fe 652,16µg/g at location EKey words: Dust sample, Malioboro street, Cr, Fe, Cu, Zn, Cd and Pb, Atomic AbsorptionSpectrophotometry

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