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INDONESIA
Buletin Penelitian Kesehatan
ISSN :  01259695     EISSN : 23383453     DOI : -
Core Subject : Health, Science,
Buletin Penelitian Kesehatan (Bulletin of Health Research) merupakan salah satu jurnal yang dipublikasikan oleh Badan Penelitian dan Pengembangan Kesehatan (National Institute of Health Research and Development), Kementerian Kesehatan Republik Indonesia. Buletin Penelitian Kesehatan diterbitkan 4 kali dalam setahun dan telah terakreditasi Lembaga Ilmu Pengetahuan Indonesia (Indonesian Institute of Sciences) dengan SK No. 387/AU/P2MI/04/2012.
Arjuna Subject : -
Articles 697 Documents
FAKTOR-FAKTOR SOSIAL BUDAYA YANG MELATARBELAKANGI RENDAHNYA CAKUPAN PENDERITA TUBERKULOSIS (TB) PARU DI PUSKESMAS PADANG KANDIS, KECAMATAN GUGUK KABUPATEN 50 KOTA (PROVINSI SUMATERA BARAT) Media, Yulfira
Buletin Penelitian Kesehatan Vol 39, No 3 Sep (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/42

Abstract

Tuberculosis (TB) Pulmonary is still one of the major health problems in Indonesia, and included in the province of West Sumatra. Many efforts has been conducted to outcome the problem, one of them is the DOTS strategy. From the results of countermeasures that have been implemented was the scope of the discovery of the TB patients are expected to 70% in Year 2009 in West Sumatra Province can only be achieved 48.8%. The study of socio-cultural factors underlying the low coverage of the discovery of pulmonary TB patients have been conducted in the region of Padang Kandis health centers, Guguk Subdistrict, District 50 City. This study uses a qualitative approach, and data collection techniques used were Focus Group Discussions (FGD) and in-depth interviews. The results showed that some socio-cultural aspects that are considered related to the low coverage of the discovery of patients with pulmonary TB are the economic aspects, education/knowledge, perceptions, habits and beliefs as well as access to health services. Knowledge and awareness in the prevention of pulmonary TB disease is still lacking. Some people still have the perception that the diseases associated with pulmonary TB supernatural power, and includes diseases that are considered shameful.
AKTIVITAS ANTIMALARIA (IN VIVO) KOMBINASI BUAH SIRIH (Piper betle L), DAUN MIYANA (Plectranthus scutellarioides (L.) R. BR.) MADU DAN KUNING TELUR PADA MEN CIT YANG DIINFEKSI Plasmodium berghei Nugroho, Yun Astuti
Buletin Penelitian Kesehatan Vol 39, No 3 Sep (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/43

Abstract

Malaria is a major public health problem in the world and developing countries in particular, causing an estimated 1-2 million deaths per year, an annual incidence of 300-500 million clinical cases and more than 2 billion people were at risk of infection from it. But it is also becoming more difficult to treat malaria due to the increasing drug resistance. Therefore, the need for alternative drugs is acute. This study aims at investigating the in vivo antiplasmodial activity of Piper betle L., fruit (buah sirih), Plectranthus scutellarioides (L.) R. BR., (daun miyana), honey and egg yolk combination. Methods: A rodent malaria parasite, Plasmodium berghei, was inoculated into Swiss albino mice. The mice were infected with Ixl05 parasites intraperitoneally. The Piper betle L., fruit (buah sirih), Plectranthus scutellarioides (L.) R. BR., (daun miyana), honey and egg yolk combination were combined and administered by an intra gastric tube daily for seven days starting from the day of parasite inoculation. The control groups received the same amount of solvent (vehicle) used to suspend each dose of the herbal drug. Chloroquine was used as a standard drug, administered through the same route. Results: Combination of Piper betle L., fruit (buah sirih), Plectranthus scutellarioides (L.) R. BR., (daun miyana), honey and egg yolk were observed to inhibit Plasomodium berghei parasitaemia in the Swiss albino mice 100 % on the sixth day. Conclusion: The study could partly confirm the claim in East Sulawesi traditional medicine that the Piper betle L., fruit (buah sirih), Plectranthus scutellarioides (L.) R. BR., (daun miyana), honey and egg yolk combination has therapeutic values in human malaria. There was, thus, the need to initiate further in-depth investigation by using different experimental models.
PELAKSANAAN STANDAR PELAYANAN KEFARMASIAN DI APOTEK DAN KEBUTUHAN PELATIHAN BAGI APOTEKERNYA Supardi, Sudibyo; Handayani, Rini Sasanti; Raharni, Raharni; Herman, M.J; Susyanti, Andi Leny
Buletin Penelitian Kesehatan Vol 39, No 3 Sep (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/44

Abstract

Decree of Pharmaceutical Care Standards in Pharmacy (PCSP) has been issued by ministry of health to improve the professionalism on handling pharmaceutical care. The aims of this study is to know implementation of PCSP, especially on drug information, drug counselling, drug use monitoring, home caring; as well as to identify the need for trainingfor the pharmacists. A cross sectional study has been done to 70 pharmacies in the City of Jakarta, Yogyakarta, Surabaya, Medan, Padang, Banjarmasin and Makassar in 2008. Data were collected through observation of the pharmacies. A focus group dis­cussion is done to Rain information from pharmacists, completed by performing a round table discussions with some expertises in Jakarta. The result showed that although PCSP has been socialized to pharmacists, the implementation of PCSP is not yet done perfectly. Training is still needed, especially on pharmacotherapy and drug information, as well as pharmacy management.
BERBAGAI KELUHAN FISIK YANG DIALAMI PASIEN OSTEOARTRITIS AKIBAT TERAPI NATRIUM DIKLOFENAK DIBANDINGKAN KURKUMINOID EKSTRAK RIMPANG KUNYIT Kertia, Nyoman; Asdie, Ahmad Husein; Rochmah, Wasilah; Marsetyawan, Marsetyawan
Buletin Penelitian Kesehatan Vol 39, No 3 Sep (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/45

Abstract

Background: The prevalence of osteoarthritis (OA) in the community is high and this disease is the second largest cause of physical disability in the world. Degeneration and joint inflammation occurred in OA. Curcuminoid is a secondary metabolite present in the rhyzome of turmeric and ginger. Curcuminoid could be used to treat rheumatic diseases. Diclofenac sodium is able to inhibite the production of prostaglandin-E2 (PG-E2) by inhibition the cycloxygenase-2 (COX-2) activity. On the other hand diclofenac sodium also inhibite the physiologic enzyme cycloxygenase-l (COX-I) activity, this inhibition may produce some complaints to the patients since the COX-l is important in body equilibrium. Objective: To assess some complaints of patients with osteoarthritis in treatment using curcuminoid from Curcuma domestica Val. rhyzome extract compared to diclofenac sodium. Method: This study was conducted with the prospective randomized open end blinded evaluation (PROBE) design. A total of 80 patients with knee osteoarthritis were included in this study (39 patients received 3x30 mg daily of curcuminoid from Curcuma domestica Val. rhyzome extract for 28 days treatment and 41 patients received 3x25 mg daily of diclofenac sodium for 28 days). The number needed to harm analysis was conducted in comparing the symptoms of head, chest, gastrointestinal and urinary tract complaints. Results: The number needed to harm (NNH) for headache was 500, palpitation was 42, shortness of breath was 42, nausea was 21, diarrhea was 42 and micturition complaints was 500. Conclusion: Although the number of patient who have chest and gastrointestinal complaints was higher in using diclofenac sodium, but no statistically significant difference either of head, chest, gastrointestinal and urinary tract complaints between the curcuminoid and diclofenac sodium treatment groups.
EFEKTIFITAS LARVASIDA ALTOSID® 1,3 G TERHADAP Aedes aegypti di LABORATORIUM * Prawoto, Shinta; Ariati, Yusniar; Wigati, Wigati; Sukowati, Supratman
Buletin Penelitian Kesehatan Vol 39, No 3 Sep (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/46

Abstract

Dengue hemmorrhagic fever (DHF) is the one of vector born diseases which is a one a public health problem in Indonesia. The distribution and number of DHF cases are increases in Indonesia every years. The vector control using larvicides should be tested to know the effectivity. This reports describes the efficacy of larvacide altosid® 1.3 g for DHF vector Aedes aegypti control in three doses 2.5%, 4% and 5%. This study was carried in laboratorium of Health Ecology Research Centre in 2010 by using WHO methods. The results shows the lethal concentration (LC50) of altosid was 2.12%, and LC 95 was 5.52%. The lethal time (LT 50) of altosid at 2.5% concentration was 8.02% and LT 95 was 12.50 %. The LT 50 and LT 95 of altosid 4% were 6.52 and 12.50 consequently, and LT 50 and LT 95 at concentration 5% were 6.72 and 9.64 consequently. The concentration of altosid at 2.5 % larva mortality was 6.4%, though at concentration 4 %, 84.8 % larvae already become pupae at the eight days after treatment, nevertheless, only 11.2% become adults stage. At the concentration of 5% have 72% pupa is formed, 10.4% were able to continue its growth into a mosquito, but eventually experience death due to abnormal growth, while the pupa is in its development has seen an abnormal experience death before they become mosquitoes. The abnormality of pupa case by this larvicide function as mimic hormon which has a mechanism to regulate the development of larva stage (IGR-Insect Growth Regulator). The mode of action of this hormon is not directly killing the larva, but to hamper the chytine formation, at the end pupa will not able to become adults or the adults stage will be abnormal.
PREFERENSI PEMINUM ALKOHOL DI INDONESIA MENURUT RISKESDAS 2007 Suhardi, Suhardi
Buletin Penelitian Kesehatan Vol 39, No 4 Des (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/47

Abstract

The problem of alcohol drinking has become public issues in some parts of Indonesia. The National Household Health Survey (NHHS) 1995 and 2001 only showed low prevalence at national level. In 2007, NHHS with a new name Riskesdas had enough sample size to elaborate health indicators even up to district levels. Riskesdas 2007 used the sample of National Socio Economic Survey (NSES) 2007. The interviewers of Riskesdas 2007 had revisited and reinterviewed 258,284 (93.0 %) out of 277,630 households with 986,532 (85.9 %) out of 1,148,418 household members of NSES 2007. Database consisted of 664,190 individual records aged 15 years and above, of which 660,349 (99.4 %) answered the questions about alcohol drinking. Individual weight and complex samples approach procedures were applied in the analysis. The objective of the study was to reveal preferences of alcohol drinkers by provinces and domiciles. The prevalence of alcohol drinking in the past month were 4.9 % in males and 0.3 % in females; while among males, 4.5 % in urban and 5.2 % in rural areas. There were 13 out of 33 provinces, all out side Jawa island, with high prevalence in males. The prevalence ranged in urban areas from 13.4 % in South East Sulawesi to 31.5 % in North Sulawesi, while in rural areas from 11.1 % in South Sulawesi to 32.9 % in North Sulawesi. The types of beverages consumed by males in urban areas were beer 33.6 %, liquor 14.4 %, wine 27.1 % and traditional alcohol 25.0 % ; while in rural areas were beer 18.6 %, liquor 6.6 %, wine 19.4 % and traditional alcohol 55.4 %. The proportions of traditional alcohol predominantly consumed in provinces with high prevalence varied in urban areas from 42.8 % in North Sulawesi to 66.2 % in North Sumatera; while in rural areas from 41.2 % in Papua to 90.7% in West Kalimantan. The findings confirmed the presence of provincial clusters and preferences of alcohol drinkers
PENGEMBANGAN PERMAINAN MULTIMEDIA INTERAKTIF TENTANG PERILAKU HIDUP BERSIH DAN SEHAT PADA SISWA SEKOLAH DASAR Pramono, Mochamad Setyo; Paramita, Astridya; Muzakiroh, Umi
Buletin Penelitian Kesehatan Vol 39, No 4 Des (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/52

Abstract

Poor environmental conditions as well as clean and healthy behaviours have not been suspected to be the cause of the high infectious diseases. Various promotional efforts have been launched clean and healthy behaviours by government to improve clean and healthy living behaviours of the Society. This study aims to develop communication techniques of Information Education and Communication such as interactive multimedia games for elementary school students to improve their knowledge about the clean and healthy behaviours and infectious diseases. The material is made of animation that shows a daily story about a boy called the Bohat (the healthy kid). The study was conducted in 2009 in Malang and Jogyakarta. The samples were Elementary student of 2nd grade of 303 students. The Design research was an experimental research design with the edu­games multimedia treatments. The result showed that edu-game is favored of the children. The content and picture colour of edu-games is the most favorable for the children. There are significant differences between the average value of knowledge clean and healthy behaviours and infectious diseases before and after treatment. This suggests showed that the edu-game is quite effectively to be used as media playing and learning on the clean and healthy behaviours and infectious diseases for elementary students.
PETA RESISTENSI VEKTOR DEMAM BERDARAH DENGUE Aedes aegypti TERHADAP INSEKTISIDA KELOMPOK ORGANOFOSFAT, KARBAMAT DAN PYRETHROID DI PROPINSI JAWA TENGAH DAN DAERAH ISTIMEWA YOGYAKARTA Widiarti, Widiarti; Heriyanto, Bambang; Boewono, Damar Tri; Widyastuti, Umi; Mujiono, Mujiono; Lasmiati, Lasmiati; Yuliadi, Yuliadi
Buletin Penelitian Kesehatan Vol 39, No 4 Des (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/54

Abstract

Insecticide resistance study to DHF vector Aedes aegypti was carried out in Central Java and Yogyakarta Provinces. The objective of this study was to map the insecticide susceptibility of Aedes aegypti population to the three chemical groups of insecticide used in public health, in Central Java and Yogyakarta. Laboratory-reared, Fl generation of field population of Aedes aegypti from eleven and three Municipalities in Central Java and Yogyakarta Provinces were used respectively. The susceptitibility test were carried out using impregnated paper base on WHO recommended doses which are 0.8% Mala­thion, 0.1 % Bendiokarb 0.75 % Permethrin, 0.05 % Lambdasihalotrin, 0.05 % Cyper­methrin dan 0.5 % Etofenproks. The results suggested that population of Aedes aegypti collected from eleven municipalities, regencies/cities in Central Java and Yogyakarta Province were resistant to Malathion 0,8 %, Bendiocarb 0.1 %, Lambdasihalotrin 0.05 % and Permethrin 0.75 %, including Deltamethrin 0.05 % and Etofenproks 0.5 %. However, in several location of this study were found the population of Ae. aegypti remain susceptible to Cypermethrin 0.05 % and Bendiocarb 0.1 %. It is important to rotate the insecticides which are used for fogging, especially Malathion.
PREVALENSI TUMOR DAN BEBERAPA FAKTOR YANG MEMPENGARUHINYA DI INDONESIA Oemiati, Ratih; Rahajeng, Ekowati; Kristanto, Antonius Yudi
Buletin Penelitian Kesehatan Vol 39, No 4 Des (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/56

Abstract

In Indonesia cancer problems was found in late stadium (70%). It has analyzed data from Riskesdas 2007-2008 to get information of prevalence by province in Indonesia, to explore odds ratio of demographic pattern and risk factors of cancer disease. Data was analyzed by descriptive and bi variate. This study showed that the highest prevalence of tumor by province was Daerah Istimewa Yogyakarta (9.66%0) and the lowest was Maluku (1.95%0). Ovarium and cervical cancer were the highest risk and blood cancer was lowest risk. Cases of cancer gave twice risk for mental health. Analyzed data of demographic proved that age influenced to cancer. Meanwhile women had twice risk in cancer than man. Beside rural area gave high risk than urban area, odds ratio in economic statue and also education rose from lowest to highest. Result of occupation analyzed exhibited that the highest odds ratio in sector of farming, fisherman and labor. Risk factors analyzed showed that Odds ratio arose up from smoking everyday category, sometimes smoking, and smoking former. According to alcohol consumption for last one year or last month was no significant. Correlation between physical activity and cancer cases had protective result. Measurement in body mass index (BM!) with WHO criteria showed that someone who had obesity especially in abdominal obesity would cause highest risk cancer than they were slim. BMI also showed had correlation to cancer disease.
UJI KEAMANAN DAN UJI DAYA TERIMA PRODUK FERMENTASI SARI PISANG KADALUARSA DENGAN KHAMIR RHODOTORULA GLUTINIS Purawisastra, Suryana; Yuniati, Heru
Buletin Penelitian Kesehatan Vol 39, No 4 Des (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/58

Abstract

Banana is a kind of fruit whose stability during storage is very short. After its ripe is over, physically the banana is very soft, with some black spot of growing the yeast over the skin. This kind of banana is already no longer acceptable as food. Actually this banana is containing high glucose content which is useful for the growth of yeasts. The object of this study is to use this over ripe bananas as the raw material for making the fermented juice drink. The yeast uses was Rhodotorula glutinis, because this yeast able to synthesis the essential nutrients of fatty acid linoleat and linolenat, ergosetrol (pro­vitamin D) and carotene pigment (pro-vitamin A). In this study also performed the safety testing which was carried out on experimental rats for along 30 days. Observations were done on physical condition of rats. At the end of observation some rats were eradicated to see the organ vital such as kidney, heart, and liver. The observation concluded that the over ripe bananas juice fermented using Rhodotorula glutinis was safety to be consumed, without any effect. Whereas its sensory evaluation which was performed by 30 tester revealed that most of the testers accepted those product of bananas juice, without any different significantly at a 0.05. Except for colour for bananas juice which was fermented had the colour of reddish due to Rhodotorula glutinis.

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