International Journal of Integrated Health Sciences
ISSN : 23021381     EISSN : 23384506
International Journal of Integrated Health Sciences (IJIHS) is a peer-review journal which publishes original articles, medical research, clinical research and case report. This journal is supported by Faculty of Medicine Universitas Padjadjaran and was launched on September 22nd 2012 and firstly published on July 2013. The first and second publications in 2013 and 2014 were published annually. In 2015 IJIHS published twice in a year, March and September.
Articles 8 Documents
Search results for , issue " VOL 5, NO 1, March (2017)" : 8 Documents clear
Prediction of Jamar Grip Strength Value Using Modified Aneroid Spyhgmomanometer Cuff Method

Pujianita, Lusia, Prabowo, Tertianto, Prananta, Marietta Shanti

International Journal of Integrated Health Sciences VOL 5, NO 1, March (2017)
Publisher : International Journal of Integrated Health Sciences

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Abstract

Objective: To examine the prediction of Jamar grip strength value by using aneroid sphygmomanometer cuff method in adults.Methods: This study involved 120 subjects, aged 20–59 years old. The grip strength of subjects were measured using Jamar dynamometer and aneroid sphygmomanometer cuff method. Spearman analysis was used to evaluate the correlation between variables and grip strength. Forward stepwise was used to analyze the regression of Jamar dynamometer using aneroid sphygmomanometer cuff method. Results: There was a weak correlation (r<0.4) between grip strength with age and BMI, moderate correlation (r = 0.4–0.6) for grip circumference, and also strong correlation r= (0.6–0.8) for sex, hand length, and hand width. Jamar grip strength value can be predicted using spyghmomanometer with the formula of (0.1157 x Sphygmomanometer grip strength value) – (5.696 x sex) + (0.0824 x age) (female =1, male= 0).Conclusions: Grip strength correlates with physiological variables. The variables to predict Jamar grip strength using sphygmomanometer are sex and age. Regression analysis shows that spyhgmomanometer can be used as an alternative to measure grip strength and has a valid value to predict the Jamar grip strength value. Keywords: Adult, grip strength, Jamar dynamometer, sphygmomanometer, prediction formula DOI: 10.15850/ijihs.v5n1.958

Relationship between Physical Activity, Anthropometry, and Forced Expiratory Volume in One Second with 6-Minute Walk Distance in Elderly

Sukarya, Irna Purnamasari, Vitriana, Vitriana, Prabowo, Tertianto

International Journal of Integrated Health Sciences VOL 5, NO 1, March (2017)
Publisher : International Journal of Integrated Health Sciences

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Abstract

Objective: To examine the correlation between physical activity using the Global Physical Activity Questionnaire (GPAQ), anthropometry (body mass index/BMI), and forced expiratory volume in one second (FEV1) value with six-minute walk distance in healthy community-dwelling elderly.Methods: A cross-sectional design study with consecutive sampling was conducted. This study included sixty nine participants (30 males and 39 females), aged ≥60 years who lives at Batununggal region in Bandung, Indonesia. The data was analyzed statistically by using normality, correlation, and multiple regresion tests. Results: The results showed that there was a correlation between six-minute walk distance and BMI in females (p=0.006), and FEV1 value in males (p=0.010). No significant correlation was found between GPAQ value and six-minute walk distance in females (p=0.4074) and in males (p=0.0926). Conclusions: There was a correlation between anthropometry and FEV1 value with six-minute walk distance in healthy elderly. There was no significant correlation between physical activity and six-minute walk distance. Keywords: Anthropometric measurement, FEV1, physical activity, six-minute walk distance DOI: 10.15850/ijihs.v5n1.963

Sapodilla (Manilkara zapota) Broth as an Alternative Media for Candida albicans

Ying, Chen Chui, Kuswardinah, Ine, Setiawati, Elsa Pudji

International Journal of Integrated Health Sciences VOL 5, NO 1, March (2017)
Publisher : International Journal of Integrated Health Sciences

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Abstract

Objective: To determine whether sapodilla can be used to grow Candida albicans. Among all the high galactose and arabinose content fruits, the sapodilla was chosen because it is available year round and can get easily in market. Other than that, it also contains vitamins, calcium and phosphorus which are very useful for fungi growth.Methods: This study used an experimental study as a method of research. The researcher culture Candida albicans on the experimental sapodilla media and identifies the morphology of the fungi by using Gram staining method. The experiment will be replicated two times to get accurate result. The procedure of this experiment constitute of sapodilla media preparation, sapodilla media observation, organism preparation, planting and incubation, observation of fungal colonies and identification of the fungi.Results: In 0%, there was no fungal growth at all. In 5%, there was mild density of fungal colonies. In 10%, there was moderate density of fungal colonies and in 15% the fungal grew with very dense colonies.Conclusions: Sapodilla (Manilkara zapota) broth can be used as an alternative media for Candida albicans.Keywords: Alternative media, Candida albicans, Sapodilla brothDOI: 10.15850/ijihs.v5n1.965

Morphological Changes of Cisplatin-resistant Human Breast Cancer MCF-7 Cell Line

Puspita, Nanda Ayu, Bedford, Amy

International Journal of Integrated Health Sciences VOL 5, NO 1, March (2017)
Publisher : International Journal of Integrated Health Sciences

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Abstract

Objective: To evaluate morphological changes of breast cancer cell line MCF-7 following the development of acquired resistance towards cisplatin. Resistance towards anticancer agents still plays an important role in the breast cancer chemotherapy failure.Methods: The cisplatin resistant subline MCF-7/CisR was developed in-vitro by cultivating the parental cell line cisplatin-sensitive MCF-7 with raising concentration of cisplatin (from 0.01 to 2.3 µM) for four months. The cell morphology was observed by giemsa staining. Results: The resistance was shown by the increase of IC50 by 9 folds on MCF-7/CisR compared to the initial IC50 value of MCF-7. The change in cisplatin cytotoxic potency on the resistant cell line was accompanied by the morphological modification, including the enlargement of cell size, the increase of nucleus and cytoplasm ratio, and the increase of the number of microvesicular and cytoplasmic granules.Conclusions: This result has supported the underlying mechanism of cisplatin resistance, including the ability of the cells to decrease intracellular cisplatin concentration and repair DNA damage effects. Keywords: Drug resistance, human breast cancer, cisplatin, MCF-7 DOI: 10.15850/ijihs.v5n1.960

Cognitive Function Profile of Post-Stroke Patients

Larasati, Dila, Defi, Irma Ruslina, Sadeli, Henny Anggraini

International Journal of Integrated Health Sciences VOL 5, NO 1, March (2017)
Publisher : International Journal of Integrated Health Sciences

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Abstract

Objective: To discover cognitive function profile of post-stroke patients undergoing rehabilitation to inform rehabilitation professionals in planning for a program and provide services that meet the patient’s need. Methods: This study was a descriptive cross-sectional study involving 32 post-stroke patients undergoing rehabilitation at the Physical Medicine and Rehabilitation clinic of Dr. Hasan Sadikin General Hospital Bandung in August–September 2014. An examination was conducted using the Mini Mental State Examination (MMSE) to obtain the cognitive function profile of post-stroke patients. Results: The results showed that almost all post-stroke patients undergoing rehabilitation had normal cognitive functions (93.8%), only few patients had probable cognitive impairment (6.2%). Probable cognitive impairment were found in male and female patients who were in the age range of 50–60 years who were elementary school graduates and in the sub acute phase of stroke. Conclusions: Almost all post-stroke patients undergoing rehabilitation have normal cognitive functions, only minority of patients have probable cognitive impairment, and there are no patients with definite cognitive impairment. Keywords: Cognitive function, education, rehabilitation, stroke DOI: 10.15850/ijihs.v5n1.962

Triamcinolone Acetonide and 5-Fluorouracil Intralesional Combination Injection in Keloid Treatment

Agusni, Jono Hadi, Sutedja, Eva Krishna, Chandra, Franky

International Journal of Integrated Health Sciences VOL 5, NO 1, March (2017)
Publisher : International Journal of Integrated Health Sciences

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Abstract

Objective: To evaluate the effectiveness of steroid and 5-fluorouracil (5-FU) injection combination for keloid management.Methods: A 22-year-old female patient was presented with recurrent skin lesions. The skin lesions first appeared 10 years prior to consultation, had been surgically excised, and were given triamcinolone acetonide injection. However, no improvement was observed. A decision was made to use and evaluate treatment using an intralesional 4 mg (0.1 ml of 40 mg/ml) triamcinolone acetonide and 45 mg (0.9 ml of 50 mg/ml ) 5-FU injection combination for 5 weeks.Results: Clinical improvements were observed in the third week as the lesions softened and pruritic sensation dinimished. At the end of the fifth week, improvements in the form of keloid lesion flattening and size reduction were observed.Conclusions: Intralesional injection using a combination of triamcinolone acetonide and 5-fluorouracil is effective for keloid lesion treatment.Keywords: 5-fluorouracil, intralesional injection, keloid, triamcinolone acetonide DOI: 10.15850/ijihs.v5n1.959

Relationship between Neutrophil-Lymphocyte Ratio and Cardiac Autonomic Neuropathy in Diabetes Mellitus Type 2 Patients

Nurlaelatiningsih, Cahyandari, Sastradimaja, Sunaryo Sastradimaja Barki, Defi, Irma Ruslina

International Journal of Integrated Health Sciences VOL 5, NO 1, March (2017)
Publisher : International Journal of Integrated Health Sciences

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Abstract

Objective: To analyze the correlation between cardiac autonomic neuropathy (CAN) and neutrophil-lymphocyte ratio (NLR) in DM type 2 patients.Methods: This was a cross-sectional study which was conducted at the Internal Medicine Clinic of Dr. Hasan Sadikin General Hospital, Bandung and Chronic Disease Management (CDM) Club in Garut District, West Java, Indonesia from October to December 2015. Subjects were 57 DM type 2 patients who met the inclusion criteria. Cardiac autonomic neuropathy examination and complete blood count (CBC) were performed to discover the subjects’ neutrophil-lymphocyte ratio. Results: A strong correlation was found between CAN in DM type 2 patients and NLR (r=0.679; p=0.000) based on Rank Spearman correlation test. The NLR to CAN cut off point was 1.34. Conclusions: NLR examination can be used as an indicator of CAN in DM type 2 patients with NLR cut off point. There was a correlation between CAN and DM type 2 diagnosis duration. Keywords: Cardiac autonomic neuropathy, diabetes mellitus type 2, Ewing test, neutrophil-lymphocyte ratio DOI: 10.15850/ijihs.v5n1.961

Incidence of Cavum Septum Pellucidum and Cavum Vergae in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Faried, Ahmad, Soeprajogo, Adolf Setiabudi, Melia, Regina, Arifin, Muhammad Zafrullah

International Journal of Integrated Health Sciences VOL 5, NO 1, March (2017)
Publisher : International Journal of Integrated Health Sciences

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Abstract

Objective: To describe the cavum septum pellucidum (CSP) and cavum vergae (CV) findings. Methods: Thirteen samples were recruited in the study. The study was conducted at the Department of Neurosurgery, Dr. Hasan Sadikin Hospital, Bandung, Indonesia in the period of 2015–2016. Thirteen samples were recruited for the study. Cavum septum pellucidum and CV spaces are relatively rare. During neurology and neurosurgery examination of patients with head computed tomography (CT) scan and magnetic resonance imaging (MRI), CSP and CV were discovered accidentally. The incidence of these unique spaces reported from many countries, but have never been reported from Indonesia.Results: This is the first-time reported incidental finding of CSP and CV from Indonesia, 13 cases in one-year period. Since the presence of CSP and CV is usually asymptomatic, clinician seem don’t really care to put it in their report.Conclusions: The presence of CSP and CV as a common incidental finding can be more revealed in our country in years to come and hopefully can be more studied in term of anatomical landmark on neurosurgical field.Keywords: Cavum septum pellucidum, cavum vergae, incidental finding DOI: 10.15850/ijihs.v5n1.964

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