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INDONESIA
Jurnal Kardiologi Indonesia
ISSN : -     EISSN : 26204762     DOI : -
Core Subject : Health,
Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other health professionals for scientific articles in the cardiovascular field. All articles (research, case report, review article, and others) should be original and has never been published in any magazine/journal. Prior to publication, every manuscript will be subjected to double-blind review by peer-reviewers. We consider articles on all aspects of the cardiovascular system including clinical, translational, epidemiological, and basic studies.
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Articles 12 Documents
Search results for , issue " Vol.28 No.3 Mei 2007" : 12 Documents clear
Menilai Fungsi Alat Pacu Jantung Menetap Yuniadi, Yoga
Jurnal Kardiologi Indonesia Vol.28 No.3 Mei 2007
Publisher : Indonesian Heart Association

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Seorang pria berusia 55 tahun dipasang alat pacujantung menetap (PJM) 6 bulan yang lalu, atas indikasidisfungsi nodal sinus yang simtomatik. Ia datang diklinik aritmia untuk pemeriksaan alat PJM, rekamanEKG diperlihatkan pada gambar 1.
Women Make the Difference in Heart Disease Maas, Angela HEM; Suryapranata, Harry
Jurnal Kardiologi Indonesia Vol.28 No.3 Mei 2007
Publisher : Indonesian Heart Association

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Cardiovascular disease develops 10 to15 years later inwomen than in men and is the major cause of death inwomen older than 65 years of age. The risk of heartdisease in women however is still underestimated andmany women are not aware of their own risk factors.In a recent report from the European Heart Survey onstable angina pectoris it was found that women areless likely to be referred for functional testing forischemia, with a lower rate of diagnostic angiogramsand interventional procedures.The under-recognition of heart disease anddifferences in clinical presentation in women lead toless aggressive treatment strategies and a lowerrepresentation of women in clinical trials. In the currentreview we summarize the major issues that areimportant in the diagnosis and treatment of coronaryheart disease (CHD) in women.
Ablasi Konvensional Kepak Atrium Atipikal Yuniadi, Yoga; Achmad, Chaerul; Munawar, Muhammad
Jurnal Kardiologi Indonesia Vol.28 No.3 Mei 2007
Publisher : Indonesian Heart Association

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Kepak atrium (KA, atrial flutter) merupakan jenisaritmia tersering kedua setelah firbrilasi atrium dalampraktek klinik. KA saat ini dibedakan berdasarkanketerlibatan ismus kavotrikuspid (IKT) dalam sirkuitreentry-nya. Di antara KA yang melibatkan IKT, KAtipikal dan tipikal terbalik merupakan jenis yang palingsering ditemukan. Semua KA yang tidak melibatkanIKT disebut sebagai KA atipikal. Pada KA atipikalsirkuit reentry kepak dapat berada di atrium kananatau kiri
Pemeriksaan BNP atau NT pro BNP pada Pasien Gagal Jantung Hersunarti, Nani; Rohman, Muhammad Saifur
Jurnal Kardiologi Indonesia Vol.28 No.3 Mei 2007
Publisher : Indonesian Heart Association

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Beberapa permasalahan masih sering dihadapiberkaitan dengan diagnosis, evaluasi keberhasilanterapi, penekanan angka morbiditas dan mortalitasgagal jantung. Seperti misalnya, pada kondisi gawatdarurat yang membutuhkan diagnosis dan terapi cepatdan akurat, kadang sulit untuk membedakan sesaknafas akibat gagal jantung atau akibat penyakit lainseperti penyakit paru dan metabolik. Hingga saatinipun pemulangan pasien dari perawatan rumah sakitsebagian besar didasarkan atas berkurangnya atauhilangnya keluhan, meskipun mungkin belumdilakukan titrasi terapi yang optimal. Hal itumenyebabkan tingginya angka kematian dan rawatulang pasien gagal jantung. Lebih jauh, hingga saat inibelum ada metoda yang rutin dipakai untuk mengevaluasi efek dari terapi yang telah diberikan pada level molekuler.Oleh karena itu, perlu ada alat diagnostik untuk mengetahui fungsi jantung secara cepat dan tepat, yang dapat membedakan sesak karena gagal jantung atau faktor lain, dan dapat pula menjadi predikor prognosis pasien gagal jantung.
Peran Pembedahan Pada Sindroma Vena Cava Superior Akibat Tumor Mediastinum Pengalaman Di RS. Persahabatan Januari 1995 – Maret 2005 Kartika, Ronald W; Busro, Ismid DI; Wibawanto, Agung; Busro, Frans B; Tabrani, Marsobo
Jurnal Kardiologi Indonesia Vol.28 No.3 Mei 2007
Publisher : Indonesian Heart Association

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Twenty eight cases of superior caval vein syndrome due to mediastinal tumor were found in The National Respiratory Centre - Persahabatan Hospital, since January 1995 until March 2005. Sixteen patien underwent internal jugular vein to right atrium grafting, with mortality rate of 6.25%. Patology anatomy examination confirmed thymoma in 13 patients, giant cell tumor in 1 patient, teratoma in 1 patient and Hodgin Limpoma nodular type in 1 patient. We conclude that internal jugular vein to right atrium grafting is a save procedure, and very beneficial as a palliative procedure for superior caval vein syndrome.
Cardiac Resynchronization Therapy Kapan dapat kita lakukan? Priyana, Andria; Irmalita, dr
Jurnal Kardiologi Indonesia Vol.28 No.3 Mei 2007
Publisher : Indonesian Heart Association

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Studi mengenai terapi neurohormonal telahmencapai puncaknya, tambahan terapi selainpenghambat renin-angiotensin-aldosteron danadrenergik, belum terbukti memberi tambahanmanfaat yang signifikan. Sementara itu, laporan studimengenai device therapy (pacemakers, implantabledefibrillators, dan ventricular assist devices) pada GJbanyak yang memberi hasil positif.3 Khusus mengenaicardiac resynchronization therapy (CRT), telahbanyak studi yang melaporkan manfaatnya pada GJ,dan telah pula dimasukkan dalam guideline HeartFailure sebagai salah satu terapi GJ. Meski demikianhasil pemasangan CRT masih bervariasi, danmembawa risiko komplikasi. Oleh karenanya,pemasangan CRT memerlukan kriteria seleksi pasienyang ketat dan tepat, sehingga rasio keuntungan-risiko dapat optimal.
Predictive Value of Terminal QRS Distortion in Anterior Wall Acute Myocardial Infarction Masrul, dr; Setianto, Budhi; Haryono, Nur
Jurnal Kardiologi Indonesia Vol.28 No.3 Mei 2007
Publisher : Indonesian Heart Association

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Background. The initial ECG at patients with Acute Coronary Syndrome, especially STEMI can predict size of infarction, response to reperfusion therapy and long term prognosis. A new classification, the QRS distortionhave increased mortality rates and larger infarct size and less limitation of their infarct size by thrombolytic therapy. QRS distortion is the emergence of J point = 50% of R wave in leads with qR configuration (I, aVL, V4-V6), or disappearance of the S wave in leads with Rs configuration (V1-V3).Methods and results. This study is cohort-retrospective to patients with anterior IMA treated by thrombolytic at National Cardiovascular Centre – Harapan Kita, Jakarta, Indonesia, during January 2003 – September 2004,that fulfill inclusion and exclusion criterias. They were divided into two group, with QRS distortion (+) and without QRS distortion (-); each group consist of 30 patients. Correlation between the two groups were analyzed by t test, chi-square test, Mann Whitney u test and logistic regression.Patients age range is 40 – 69 years, and mostly man. There is no difference between baseline characteristic in the two groups, except cholesterol LDL which is higher in the group with QRS distortion. Patients with QRS distortion have a higher tendency of thrombolytic therapy failure compare to patients without QRS distortion, (p=0,003). As the consequence they also have a higher rate of arrhythmia events, low ejectionfraction and re-hospitalization due to congestive heart failure.Conclusions. The prognosis of patients with anterior IMA associated with QRS distortion is worse than without QRS distortion.
Surgical Risk for Adult with Tetralogy of Fallot Wilamarta, Karina V; Fakhri, Dicky; Rachmat, Jusuf
Jurnal Kardiologi Indonesia Vol.28 No.3 Mei 2007
Publisher : Indonesian Heart Association

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Background. The beneficiaries of successful pediatric cardiac surgery and cardiology increases surgical treatment in the adult population with congenital heart disease. Adults patient with Tetralogy of Fallot (TOF) will need surgery either reoperative, palliative or more commonly reparative by the time they come. Many of them face the prospect of further operations, arrhythmias, complications and if managed inappropriately will increase risk of heart failure and premature death. This study presents the early surgical results of adult TOF.Methods and results. Data were reviewed retrospectively related to the hospital course of TOF adult patients (age > 17 years) from June 1, 1998to December 30, 2006 who require surgical treatment in National Cardiac Center - Harapan Kita, Indonesia. Most of the operations were corrective procedures (20 patients, 66.7%), followed by palliative procedures (6patients, 20%), and reoperations (4 patients, 13.3%). Mean age at surgery was 20.87+5.49 years. There were no hospital mortality in the primary corrective group, one death (16.7) in the palliative group related to poorleft ventricular function, and one death (25%) in the reoperation group related to perioperative bleeding. Follow up data of 11.73+17.68 months duration were available in 28 of 30 patients (93%) who were discharged home. Overall survival probability is higher for corrective procedures than palliative and reoperative procedures.Conclusions. Surgical treatment of TOF in adult patients proved quite save and beneficial
Quality of Life Evaluation After Coronary Artery Bypass Graft Surgery in Patient who Underwent Phase III Rehabilitation Program Abdurachim, Kiki; Kalim, Harmani; Radi, Basuni
Jurnal Kardiologi Indonesia Vol.28 No.3 Mei 2007
Publisher : Indonesian Heart Association

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Background. Coronary artery bypass graft surgery (CABG) is one of the management for coronary artery disease. Cardiovascular rehabilitation usually conducted for recovery and improved quality of life. Questionnaire was used to evaluate quality of life. One of the quality of life instrument most commonly used is Questionnaire SF-36. So far there isn’t any studyto evaluate quality of life in patients post CABG who wish to follow rehabilitation program phase III in Indonesia.Methods and results. This is a cross sectional study conducted in the National Cardiovascular Centre (NCC) - Rehabilitation Division to patients post CABG in phase III rehabilitation program during 2004-2005. Subjectwas taken in consecutive sampling manner. Questionnaire SF-36 was handed directly or via mail. Validity and reliability test was done for the questionnaire form in Indonesia language. There were 112 patients, 34 patients did rehabilitation program in hospital and 78 were home-based. The characteristics between two groups were similar. Validity test using rproduct moment from Pearson to every questions in SF-36 showed r =0,53-0.83 > 0,51 (r table) and Cronbach α= 0,855. SF-36 scoring was not significantly different among the two groups (in hospital rehab vs homebased rehab) and also control group (healthy).Conclusions. There were no difference in quality of life and aerobic capacity in patients who performed rehabilitation program phase III in hospitaland home-based.
The Effect of Moringa Oleifera Leaf Extract in Inhibition of NFκB Activation, TNF-α and ICAM-1 Expression in Oxydized LDL treated HUVECS Wihastuti, Titin Andri; Sargowo, Djanggan; Rohman, Muhammad Saifur
Jurnal Kardiologi Indonesia Vol.28 No.3 Mei 2007
Publisher : Indonesian Heart Association

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Background. Atherosclerosis is a chronic inflammation process of vascular endothelial cells. Increased oxydized LDL (OxLDL) is one of the most potent inducer of atherogenesis. OxLDL induces an increased ROS (Reactive Oxigen Species) and also acts as cytotoxic and chemotaxis factor for monocytes result in accumulation of inflammatory cells. Nuclear FactorKappa Beta (NFkB) is a transcription factor that plays an important role in this inflammatory proces. NFkB compose of heterodimer molecules of p50 and p65, which bind to its inhibitor, IkB, leading to its inactive form in cytoplasm. OxLDL activates NFkB complex by phosphorylate IkB resulting in released p50-p65-IkB binding and translocation of p50-p65 into the nucleus. p50-p65 then binds to promoter and activates transcription of target genes. NFkB activation therefore increase gene and protein expressions of target molecules such TNF-α, ICAM-1, VICAM, etc. This study aimed to examine whether Moringa oleifera inhibits activation of NFkB dan expression of cytokine TNF-α and adhesion molecule ICAM-1.Methods and results. Human umbilical vein endothelial cells (HUVECs) treated with OxLDL were used as model of atherosclerosis. The increased NFkB activity was measured by indirect method using p50 subcellular localization by immunohistochemistry. 40ug/mL OxLDL, 0.01 gr/mL and 0.005 gr/mL Moringa oleifera were used based on preliminary study.Conclusions. This study showed that OxLDL significantly induce NFkB activation and increase protein expression of TNF-α and (ICAM-1). This study also observed that Moringa oleifera significantly inhibit NFkB activation,and prevent an increased TNF-α and ICAM-1 expression at protein level in OxLDL-treated HUVECs as compare to the controls. Moringa oleifera dose of 0.01mg/mL has a better inhibition effect as compare tothat of 0.005 gr/mL.

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