Biomolecular and Health Science Journal
Published by Universitas Airlangga
ISSN : -     EISSN : 26208636
Bimolecular and Health Science Journal (BHSJ) is a scientific peer-reviewed medical doctor which relevant to a medical doctor and other health-related professions by the Faculty of Medicine Universitas Airlangga, Indonesia. BHSJ provides a forum for original article, review article, editorial, case report(s), letter(s) to the editor, short communication and it will be published two times a year. Studies that focus on evaluating and understanding the complex medical importance are welcomed in BHSJ.
Articles 38 Documents
Correlation Between Nutritional Status Of Children Aged 12 – 36 Months And Mother’s Working Status In Taman, Sidoarjo Nugraheningtyasari, Nur Annisa; Soemayarso, Ninik Asmaningsih; Susanti, Dwi
Biomolecular and Health Science Journal Vol 1, No 2 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Original Source | Check in Google Scholar | Full PDF (206.841 KB) | DOI: 10.20473/bhsj.v1i2.9266

Abstract

Introduction: The correlation between child’s nutritional status and mother’s working status  in Indonesia is still unclear. Some research report a high prevalence of low-nourished children whose mother is working, while others report a non significant correlation between child’s nutritional status and mother’s working status.Methods: This study was case-control study, sample of low-nourished  children (treatment group) & well-nourished children (control) are taken from 21 Posyandu in Taman, Sidoarjo in 2015. All data were analyzed using Chi Square test.Results: There are 72 samples which are suitable with the inclusion criteria, consisted of 36 low-nourished children and 36 well-nourished children. From 72 samples, 28 children have a working mother and 44 children have a non working mother. There were no correlation between Mother’s working status (p=0,486), Number of children in the family (p=0,468), History of chronic disease (p=0,054) with child’s nutritional status. Level of family income, Mother’s education level, History of exclusive breastfeeding, Energy consumption level, Protein consumption level were correlated with child’s nutritional status with value (p=0,000), (p=0,002), (p=0,002), (p=0,000), (p=0,001) respectively.Conclusion: Mother’s working status is proved that is not correlated  with child’s nutritional status. But, level of family income, mother’s education level, energy & protein consumption level, and history of exclusive breastfeeding are significantly correlated with child’s nutritional status.
Primary Pulmonary Lymphoma with Superior Vena Cava Syndrome Rosyid, Alfian Nur; Meliana, Resti Yudhawati
Biomolecular and Health Science Journal Vol 1, No 2 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Original Source | Check in Google Scholar | Full PDF (199.449 KB) | DOI: 10.20473/bhsj.v1i2.9858

Abstract

Primary Pulmonary Lymphoma (PPL) is a clonal proliferation of lymphoid cells that involve one or two lungs (parenchyma and or bronchi. PPL is found in approximately 0.4% of all lymphoma cases and 3.6% of NHL cases. Five years survival rate at stage I and II is 90%, and 80% in stage III and IV. A 63-year-old male farmer presented with chief complaint of shortness of breath for one week before admission and preceded by coughing for a month, loss of appetite and night sweating. There was an abnormal physical examination on the right side of the chest with non-tender lymph node enlargements in the right supraclavicular and neck region and superior vena cava syndrome. CT guided FNAB suggesting NHL. Patient was treated with CHOP chemotherapy regiment. However, with high grade lymphoma, patient did not respond well.
Palliative Therapy of Esophageal Stent Installation with Shim Modified Fixation Techniques on An Esophageal Adenocarsinoma Patients Ayu, Yudith Annisa
Biomolecular and Health Science Journal Vol 1, No 1 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Original Source | Check in Google Scholar | Full PDF (356.917 KB) | DOI: 10.20473/bhsj.v1i1.8209

Abstract

Esophageal carcinoma is a progeny disease that often results in significant disruption to the ability to ingest solid foods and liquid foods at an advanced stage. Reported case of a 27-year-old man with a diagnosis of an intestinal type of adenocarcinoma gastroesophageal junction stage III with a dysphagia score 4. Diagnosis based on anamnesis, endoscopy and anatomical pathology. Patients have undergone chemotherapy and palliative therapy with esophageal dilatation. Patients experienced improvement in dysphagia score from initial score 3 (unable to swallow solid or liquid food), to 2 (able to swallow semisolid food) after the installation of esophageal stent. The patient planned to continue therapy his chemotherapy.
Etiology Based on Clinical Manifestation of Acute Diarrhea Incidence of Children Hospitalized in Dr. Soetomo General Hospital Surabaya Period 2011-2013 Imanadhia, Ashfahani; Ranuh, IGM Reza Gunadi; Nuswantoro, Djohar
Biomolecular and Health Science Journal Vol 2, No 1 (2019): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v2i1.12744

Abstract

Introduction: Diarrhea is one of the most common causes of morbidity and mortality of children worldwide, especially in developing countries. Acute diarrhea can occur from a large number of causes. We aim to describe the clinical manifestation characteristics of acute diarrhea on pediatric patients that are presented to the hospital.Methods: A cross-sectional study from all pediatric patients treated in Dr. Soetomo General Hospital Surabaya in 2011-2013.Age, gender, nutritional status, length of hospital stay, duration of breastfeeding, clinical signs and symptoms, as well as laboratory results collected and analyzed descriptively.Results: One hundred and fifty patients were included with characteristics of male(54%), infant (55.3%)with a mean age of 6-7 month. History of being exclusively breastfed(54%) and lack of nutrition(48%). Vomiting is mostly present (72.7%) and commonly come with a combination of two symptoms (42%) which were vomiting and fever. Mild to severe dehydration degree could be found on the patient who had vomiting, seizure, and fever. The most length of stay was frequently >72 hours. The occurrence of acute diarrhea on a child who was treated in Dr. Soetomo General Hospital Surabaya is dominated by vomiting and it could be inferred that the most acute diarrhea has a tendency of being caused by a virus, where liquid acute diarrhea without blood, mucus, or fever is found.Conclusion: The etiology of acute diarrhea is mostly caused by viruses and symptoms dominated by a combination of vomiting, fever, and diarrhea without blood caused by villi damage.
Antibacterial Effects of Fluoride in Streptococcus mutans Growth in Vitro Pradiptama, Yura; Purwanta, Marijam; Notopuro, Harianto
Biomolecular and Health Science Journal Vol 2, No 1 (2019): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Original Source | Check in Google Scholar | Full PDF (266.927 KB) | DOI: 10.20473/bhsj.v2i1.13232

Abstract

Introduction: Streptococcus mutans is a gram-positive coccus commonly found in the human oral cavity and is a pathogen of dental caries. S. mutans known to form biofilm in infective endocarditis heart-valve. Fluoride usage known to reduce the risk of dental caries. This study aims to analyze how usage of fluoride in inhibiting S. mutans growth.Methods: This study was an experimental study. Antibacterial activity test was performed to evaluate the minimum inhibitory concentration (MIC) using dilution method of sodium fluoride. The minimum bactericidal concentration (MBC) was determined by culturing from the previous dilution test into Chocolate Agar Plate.Results: MIC for sodium fluoride is 4,8 mg/ml and the MBC for sodium fluoride to S. mutans is 4,8 mg/ml. We found S. mutans growth in higher concentration than 19,2 mg/ml. Conclusion: S. mutans was inhibited in dilution test. Growth of the bacteria in higher concentration of sodium fluoride is explained with quasi-irreversible inhibtior effects of fluorida.
Bacteria Pattern, Results of Antibiotic Sensitivity Test, and Complications of Deep Neck Abscess Patients in Dr. Soetomo General Hospital Rijal, Syaiful; Romdhoni, Achmad C.
Biomolecular and Health Science Journal Vol 1, No 2 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Original Source | Check in Google Scholar | Full PDF (513.641 KB) | DOI: 10.20473/bhsj.v1i2.9832

Abstract

Introduction: Deep Neck Abscess is the accumulation of pus inside the potential space between the deep neck fasciae. The incidence has decreased dramatically since the antibiotic era. Empirical antibiotics are administered before the sensitivity test results out, so it is important to know the map of bacteria and its resistance.Methods: This study was conducted retrospectively using medical records of patients with deep neck abscess in Dr. Soetomo General Hospital Surabaya during January 2014-December 2017. Data recorded included gender, age, location, results of bacteria culture examination, antibiotic sensitivity test, and complications that occurred. Data is processed descriptively. Results: Of the 162 patients, 102 (62.96%) were males, followed by 60 females (37.04%). The 46-60 years old group has the largest percentage (33.95%). Whereas the most common location of abscess was in the submandibular (42.59%). Pus culture test, most bacteria is Klebsiella pneumonia (13.04%). While the sensitivity test shows that meropenem has the highest sensitivity number (73.58). Most complications were sepsis, in 48 patients (29.63%). Conclusion: Klebsiella pneumonia, Staphylococcus aureus, and Streptococcus anginosus are the most common etiologies in deep neck abscess. Meropenem, cefoperazone-sulbactam, and oxacillin are the most sensitive antibiotics.
Age as the Risk Factor that Affected the Increased Degree of Uterine Prolapse Sayko, Shervil Kagayaita; Kurniawati, Eighty Mardiyan; Lestari, Pudji
Biomolecular and Health Science Journal Vol 1, No 1 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Original Source | Check in Google Scholar | Full PDF (480.596 KB) | DOI: 10.20473/bhsj.v1i1.8210

Abstract

Introduction: Uterine prolapse is a gynecological problem that women often experience with a prevalence of 50% and is predicted that the next 30 years will increase by 45% as life expectancy increases. Increased degrees of uterine prolapse have an impact on the deterioration of women's quality of life. The uterine prolapse is influenced by several mutually supportive factors. The purpose of this study was to analyze the relationship between these factors to the degree of uterine prolapse.Methods: This research is an observational analytic research with cross sectional approach. The number of samples were 65 patients with uterine prolapse at Policlinic Gynecology RSUD Dr. Soetomo Surabaya from 2015-2017. Sampling was done by consecutive sampling. To find out the significant level, the collected data will be tested with Fisher Exact Test statistic at significance level α = 0,05.Results: The result showed that there was significant difference between degree of uterine prolapse with age factor (p = 0,016) and obesity (p = 0,041). As for the parity factor (p = 0.508) there was no significant difference between the parity factor and the degree of uterine prolapse.Discussion: Age is a major factor affecting the degree of uterine prolapse, weakening of pelvic floor tissue and muscle in elderly women is the main cause. While on the obesity factor, there is no data to support that obesity is related to the degree of uterine prolapse because the trend indicates that the majority of patients are not obese. In contrast the parity factor, although according to the statistical test there is no difference to the degree of uterine prolapse, the trend shows that parity leads to increased incidence of uterine prolapse itself.Conclusion: Age is a factor that affects the degree of uterine prolapse.
Characteristic of Referral Patients With Severe Preeclampsia In Surabaya adeline, myrna evanda; Laksana, Muhammad Ardian Cahya; Atika, S
Biomolecular and Health Science Journal Vol 1, No 1 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v1i1.8219

Abstract

Introductions: Pre-eclampsia is a hypertensive disorder of a pregnancy that remains major maternal mortality in developing country. Severe pre-eclampsia needed an advanced medical treatment since it could cause life treathening condition for both mother and fetus. The purpose of this research was to understand and got the  picture of the age, parity, complication, delivery method, referral pathway, age of pregnancy, birth weight, and Apgar score of baby from pre-eclamptic mother in dr. Soetomo General Hospital during 2011.Methods: This research is a retrospective-descriptive research which observed the age, parity, complication, delivery method, referral pathway, age of pregnancy, birth weight, and Apgar score of baby from pre-eclampsia mother This research used medical record then the data was recorded and analyzed  descriptively.Result: The number of patients who met the inclusion criteria were 239 patients. Patient’s age were distributed unimodally with a peak at productive age. Most of patients had previous history of pregnancy. Pulmonary edema was the most common cause of maternal complication and intra uterine fetal death was the most common cause of fetal complication. Most delivery were performed in Sectio Caesaria method. Almost all cases was direct refferal cases from other medical services. Then most of cases was reaching aterm periode. Most of babies were born with body weight ≥ 2500 gram. And based on Apgar score the babies were well adapted.Conclusions: Most of the patients with severe preeclampsia referrals were referred from a health care setting, only a small percentage of women were referred to relay. Most of severe preeclampsia occured in women with their gestational age has reached 37 weeks.
Head Computed Tomography Images of HIV/AIDS Patients with Suspected Cerebral Toxoplasmosis in Dr. Soetomo General Hospital Surabaya Wibawani, Ria; Soeprijanto, Bambang; Ferriastuti, Widiana; Triyono, Erwin A
Biomolecular and Health Science Journal Vol 2, No 1 (2019): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Original Source | Check in Google Scholar | Full PDF (257.739 KB) | DOI: 10.20473/bhsj.v2i1.13343

Abstract

Introduction: Toxoplasma gondii is an intracellular pathogenic parasite with the majority of co-infections occurring in HIV/AIDS patients. This study assesses the head computed tomography (CT) images of cerebral toxoplasmosis in patients with HIV/AIDS.Methods: This study was a cross-sectional design using head CT images of 35 HIV/AIDS patients with suspected cerebral toxoplasmosis. Variables include lesion type, location, size, CD4 count, and therapeutic result with anti-cerebral toxoplasmosis. All data analysed descriptively.Results: From total 110, 35 patients met the inclusion criteria. 24 patients (68.6%) were male and 11 (31.4%) female, average age, was 36.1. 8 patients (22.3%) had lesions in cortical, 31 patients (88.6%) had < 1 cm lesion. Single lesions mainly calcified and found in the right centrum semiovale while multiple lesions were subcortical. A hypodense lesion with rim or nodular contrast enhancement is found in 75% of patients with CD4 > 200 in contrast to slight rim contrast enhancement and perifocal edema in patients with CD4 < 200. 20 patients (57.4%) had improved condition after anti-toxoplasmosis therapy.Conclusion: Cerebral toxoplasmosis lesions in HIV/AIDS patients have various types of imaging findings, mostly multiple, with most frequent location being cortical and diameter < 1 cm. Total recovery is achieved in the majority of patients with therapy.
Depression Level Difference Between Gifted and Non-gifted Medical Students Alkaff, Firas Farisi; Syamlan, Adila Taufik; Jonatan, Michael; Nugraha, Rcardo Adrian; Octora, Tan Nicko; Karimah, Azimatul
Biomolecular and Health Science Journal Vol 1, No 2 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Original Source | Check in Google Scholar | Full PDF (172.711 KB) | DOI: 10.20473/bhsj.v1i2.9716

Abstract

Introduction: Depression is a common mental health conditions in the world. Compare to general population, the prevalence of depression in medical students are higher. There are several risk factors that might contribute to the higher rate of depression in medical students, including being a gifted student. However, no study has been published regarding the depression of the gifted medical students until now.Aim: To find out the difference in the level of depression between gifted and non-gifted medical students. Methods: This study was a descriptive cross-sectional study, conducted from October to December 2016. Subjects were third year medical students from Faculty of Medicine Universitas Airlangga. There were 2 groups in this study. Samples from gifted students group was obtained using total sampling method, while number of samples from non-gifted students group was equated with gifted students group. Depression was measured using Beck Depression Inventory (BDI). Mann-Whitney U test was used for statistical analysis.  Results: 34 students, 17 students in the gifted students group and 17 students in the non-gifted students group, were included in this study. Based on the BDI score results category, 2 students from the gifted students group and 1 student from non-gifted students group were in the mild category, and 1 student from the gifted students group was in the borderline category. The highest BDI score in gifted students group were 14, while in non- gifted students group were 17. There was no significant difference of the BDI score and BDI category between groups (p = 0.154; 0.951, respectively).Conclusion: There was no significant difference of depression level between gifted and non-gifted medical students.

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