cover
Contact Name
Dr. Erina Yatmasari, dr.,M.Kes.
Contact Email
erina.yatmasari@gmail.com
Phone
-
Journal Mail Official
biomedicina@hangtuah.ac.id
Editorial Address
-
Location
Kota surabaya,
Jawa timur
INDONESIA
Oceana Biomedicina Journal
ISSN : -     EISSN : 26140519     DOI : -
Core Subject : Health, Science,
Hyperbaric medicine, marine medicine other than hyperbaric, on ships, boats and harbor health, maritime and coastal health, medicolegal aspects and medicolegal related to ships, ports and districts / maritime / coastal communities and fishermen, epidemiological aspects of diseases, disabilities and disorders both major and minor occurs of ships and boat workers, ports and maritime zones, coastal areas, fishermen communities and their families, including pharmacological and non-pharmacological prevention and treatment management policies.
Arjuna Subject : -
Articles 5 Documents
Search results for , issue " Vol 1, No 1 (2018): Oceana Biomedicina Journal" : 5 Documents clear
HIV Infection: Immunopathogenesis and Risk Factor to Fishermen Budiarti, Retno
Oceana Biomedicina Journal Vol 1, No 1 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v1i1.4

Abstract

Infeksi primer terjadi bila virion HIV dalam darah, semen, atau cairan tubuh lainnya dari seseorang masuk ke dalam sel orang lain melalui fusi yang diperantarai oleh reseptor gp120 atau gp41. Tergantung dari tempat masuknya virus, sel T CD4+ dan monosit di darah, atau sel T CD4+ dan makrofag di jaringan mukosa merupakan sel yang pertama terkena. Sel dendrit di epitel tempat masuknya virus akan menangkap virus kemudian bermigrasi ke kelenjar getah bening. Sel dendrit mengekspresikan protein yang berperan dalam pengikatan envelope HIV, sehingga sel dendrit berperan besar dalam penyebaran HIV ke jaringan limfoid. Di jaringan limfoid, sel dendrit dapat menularkan HIV ke sel T CD4+ melalui kontak langsung antar sel.
Extended Spectrum Beta-Lactamase ( ESBL ) Biutifasari, Verna
Oceana Biomedicina Journal Vol 1, No 1 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v1i1.3

Abstract

Antibiotika telah banyak digunakan sekarang ini. Pemakaian antibiotika yang berlebihan dan tidak sesuai dengan klinis dapat menyebabkan terjadinya resistensi terhadap antibiotika tersebutSalah satu antibiotika yang dipakai adalah antibiotika golongan beta-lactam yang bekerja menghambat dinding sel. Pemakaian antibiotika beta-lactam yang tidak sesuai dapat menyebabkan terjadi resistensi terhadap antibiotika tersebut. Resistensi terhadap beta-lactam dapar terjadi di berbagai tingkatan. Salah satu resistensi dapat terjadi adalah  resistensi terhadap extendedspectrum broad lactamase (ESBL)Extended spectrum beta-lactamase adalah enzim yang mempunyai kemampuan dalam menghidrolisis antibiotika golongan penicillin, cephalosporin generasi satu, dua, dan tiga serta golongan monobactam dan menyebabkan resistensi ke seluruh antibiotika tersebut.ESBL banyak dihasilkan oleh Enterobactericeae (terutama Escherichia coli) dan Klebsiella pneumoniae. Enterobacteriaceae mempunyai 3 pola resistensi yang disebabkan broad spectrum beta-lactamase,inhibitor resistant beta-lactamase (derivat TEM) , Cephalosporinase yang berlebihan. ESBL dapat sulit terdeteksi karena ESBL mempunyai perbedaan tingkatan aktifitas terhadap bermacam-macam cephalosporinESBL dapat dideteksi secara clinical microbiology (phenotypic) dan molecular detection (genotypic). Keywords: Antiobiotika, resistensi, ESBL
Recent Therapeutics Policies of Arthritis Rheumatoid (part I) Andisari, Hendrata Erry
Oceana Biomedicina Journal Vol 1, No 1 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v1i1.2

Abstract

Therapy in RA has undergone many advances today and in line with knowledge of the pathogenesis of RA, the current therapeutic goal is to alter the journey and control the activity of RA disease. Several groups of drugs have been used in RA therapy including non-steroidal anti-inflammatory drugs (NSAIDs), conventional disease-modifying antirheumatic drugs (DMARDs) as well as biological agents (bDMARD), glucocorticoids and anti-pain medicines. In recent years, the development of biological agents that have specific targets for inflammatory mediators such as interleukin (IL) -1, IL-6 and Tumor Necrosis Factor (TNF) suggests a potent therapeutic effect on RA. In this article will be presented the latest biological agents as the latest therapy on RA.
Ethanolic Extract of The Graptophyllum Pictum Griff Leaves as Antipyretic agent to Male White Rat Rikomah, Setya Enti; Lestari, Gina; Winanti, Juwita
Oceana Biomedicina Journal Vol 1, No 1 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v1i1.5

Abstract

Utilization of plants as traditional medicinal are still always be  used by people in Indonesian. Especially in rural areas that  still rich with variety of plants. Plants  of black pudding leaves (Graptophyllum pictum Griff) are one that efficacious for treating various of diseases. The content of  flavonoid  in the black pudding leaves have  antipyretic effect, analgesic and anti-inflammatory. This research aims to find  out  whether the black pudding leaves have  antipyretic effect or not. This research  used the induction method  of vaccineDPT-Hb 0.022 / 20 gr a white rat as stimulant fever. Positive control with paracetamol 1.3 mg / 20 gram a white rat, negative control with Na CMC 0.5 ml / 20 grams a white rat, first extract test of black pudding leaves  0.8 mg / 20 gram a white rat, second extract test of  black pudding leaves 1.6 / 20 gram a white rat, and third extract test  of black pudding leaves 3.2 / 20 gram a white rat. The results of research showed that ethanol extract of black pudding leaves if it’s looked from  statistic result of SPSS 16 program , it doesn’t  show out of any effect as antipyretic effect because  the significant value  is P> 0.05.Keywords: Antipyretic, DPT vaccine Hb, (Graptophyllum pictum)
The infection of Vibrio parahaemolyticus in shrimp and human Praja, Rian Ka
Oceana Biomedicina Journal Vol 1, No 1 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v1i1.6

Abstract

Vibrio parahaemolyticus is an aquatic zoonotic agent that can threaten human and aquaculture animal health. Humans can be infected by consuming contaminated raw seafood or wound-related infections. Generally infection of V. parahemolyticus is orally transmitted and causes gastroenteritis in humans while in aquaculture animals especially shrimp can cause Acute Hepatopancreatic Necrosis Disease (AHPND) or Early Mortality Syndrome (EMS) with a very high mortality rate and cause economic losses. Shrimp species susceptible to infection are Litopenaeus vannamei, Penaeus monodon, and P. chinensis. V. parahaemolyticus produces several toxins in human disease such as thermostable direct hemolysin (TDH), TDH-related haemolysin (TRH), and thermolabile hemolysin (TLH). Meanwhile, Photorabdus insect-related (Pir) toxins consisting of PirAvp and PirBvp are the toxins associated with AHPND in shrimp. The genes that encode the toxin are used as targets to diagnose V. parahaemolyticus pathogens molecularly. Until now the treatment of V. parahaemolyticus infection is using antibiotics and fluid therapy, but there were V. parahaemolyticus isolates from aquaculture that have been resistant to antibiotics so that the use of antibiotics in aquaculture must be controlled and the use of alternative therapy are very important to be developed to control V. parahaemolyticus infection. Keywords: V. parahaemolyticus, zoonotic, gastroenteritis, Acute Hepatopancreatic Necrosis Disease (AHPND), Early Mortality Syndrome (EMS).

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