Borneo Journal of Pharmacy
ISSN : 26214814     EISSN : -
The publication of Borneo Journal of Pharmacy certainly participates in disseminating the results of research and review of science and technology development conducted by lecturers and researchers especially from UM Palangkaraya and other universities. This edition contains 12 articles consisting of Pharmacognosy-Phytochemistry, Natural Product Development, Clinical-Community Pharmacy, and Management Pharmacy.
Articles
22
Articles
Antibacterial Activity of Ethanolic Extract of Sangkareho (Callicarpa longifolia Lam.) against Staphylococcus epidermidis

Novaryatiin, Susi, Sari, Asmaul Ayuriska, Mulyani, Evi

Borneo Journal of Pharmacy Vol 1 No 2 (2018): Borneo Journal of Pharmacy
Publisher : ​Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya

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Abstract

One of the plants believed as traditional medicine by the Dayak tribes in Central Kalimantan was Sangkareho (Callicarpa longifolia Lam.). This plant was usually used as traditional medicine by society in Puruk Cahu, Murung Raya Regency, Central Kalimantan and empirically believed could cure skin disease such as wound infection. This study was aimed to determine the antibacterial activity of ethanolic extract of Sangkareho (Callicarpa longifolia Lam). Antibacterial activity of ethanolic extract of Sangkareho was performed using disc diffusion technique, with four variations of concentration of 1%, 5%, 10%, and 15%. In this present study showed that ethanolic extract of Sangkareho has antibacterial activity against Staphylococcus epidermidis, wherein the resulting inhibition zone diameter was 7.3±0.8 mm, 8.3±1.2 mm, 10.5±0.5 mm, and 12.2±0.7 mm, respectively. Further research is needed to obtain an antibacterial activity of the fraction of Sangkareho.

Cover, Content, and Editorial Note from Borneo J Pharm Vol. 1 No. 2 November 2018

Borneo J Pharm, Chief Editor of

Borneo Journal of Pharmacy Vol 1 No 2 (2018): Borneo Journal of Pharmacy
Publisher : ​Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya

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Abstract

Alhamdulillahirabbil ‘alamin. The next edition of Borneo Journal of Pharmacy (Borneo J Pharm), has been published in November 2018. This journal aims to publish high-quality articles dedicated to all aspects of the latest outstanding developments in the field but not limited to Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, Clinical-Community Pharmacy, Management Pharmacy, and other Pharmacy aspects. It was first published online in May 2018 using Open Journal System (OJS) 3.1 platform with e-ISSN 2621-4814 by url http://journal.umpalangkaraya.ac.id/index.php/bjop. This edition contains eight articles consisting of Pharmacology-Toxicology, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, and Clinical-Community Pharmacy topics. Editorial boards are fully aware that there is still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next versions. The editorial board would like to thank the University, all editors and reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors of the materials, could re-participate for the success of the publication in the next edition in May 2019.

Tingkat Kepuasan Pasien terhadap Pelayanan Kefarmasian di Puskesmas Pahandut Kota Palangka Raya

Chusna, Nurul, Fetriana, Titra, Adawiyah, Rabiatul

Borneo Journal of Pharmacy Vol 1 No 2 (2018): Borneo Journal of Pharmacy
Publisher : ​Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya

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Abstract

This study aims to determine the level of patient satisfaction with pharmaceutical services at the Pahandut Palangka Raya Community Health Center. This research method is descriptive. The sample in this study were 94 respondents, namely outpatients who received pharmacy services at the Pahandut Palangka Raya Community Health Center. The sampling technique in this study used a purposive sampling technique. The results of the study of patient satisfaction with pharmaceutical services based on the type of service obtained a score of 208 data located in the "very satisfied" area on the type of pharmacy staff responsiveness to patients, in the type of hospitality services pharmacy staff obtained a score of 206 data located "very satisfied", the types of clarity of pharmacy services in providing drug information obtained a score of 212 data located in "very satisfied" areas, in the type of drug service speed the score data 199 were found in "very satisfied" areas, in the types of medical services and medical devices the score data was obtained 200 lies in the "very satisfied" area, in the type of waiting room comfort service the 198 score data is located in the "very satisfied" area, and on the type of service the availability of brochures, leaflets, posters, as well as drug/health information is obtained score data 206 lies in the "very satisfied" area. The results of this study indicate that most patients were very satisfied with the pharmaceutical services provided by the Pahandut Community Health Center in Palangka Raya City.

Utilization of Catechins in Sunscreen Lotion Formulation

Kamal, Sefrianita, Rusdi, Mesa Sukmadani

Borneo Journal of Pharmacy Vol 1 No 2 (2018): Borneo Journal of Pharmacy
Publisher : ​Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya

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Abstract

Skin is the outermost part of the body which is susceptible to solar radiation. Excessive radiation from ultraviolet (UV) rays can harm the skin, such as premature aging effect, erythema, and even skin cancer. Antioxidant compounds are needed to protect the skin from excessive exposure of UV rays. The antioxidant can be useful as a defense system against free radicals, ultraviolet radiation, and air pollution. One source of antioxidant from nature is Catechins. Catechins are obtained from the isolation of gambir (Uncaria gambir Roxb). Besides being useful as an antioxidant, Catechins also have antibacterial, antiseptic and wound healing effect. The antioxidant activity of Catechins can absorb UV rays, provides protection against oxidative stress, inflammation, and skin cancer. Therefore, the research is necessary to utilize the catechins in sunscreen lotion formulation. Catechins are isolated from gambir by maceration with hexane and ethyl acetate (polar, nonpolar and residual fractions). The fraction which yields the most catechins is used as the active substance in the formulation. The formulation is divided into 4 lotion formulas, namely Formula 1 with 0.5% catechins concentration, Formula 2 with 7.5% catechins concentration, Formula 3 with 1% catechins concentration, and Formula 4 without catechins substance. Physical stability test and effectiveness of sunscreen formulation are carried out on 4 lotion formulas. Physical stability tests included organoleptic observation, homogeneity, pH, and assessment of the effectiveness of sunscreen formulation by using UV-Vis Spectrophotometer.

Effect of Giving Celecoxib on Uric Acid Level on Mice

Surya, Sara

Borneo Journal of Pharmacy Vol 1 No 2 (2018): Borneo Journal of Pharmacy
Publisher : ​Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya

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Abstract

Celecoxib is a breakthrough for pain relievers under the trade name Celebrex®, which is a Non-Steroid Anti-Inflammatory drug with its activity as an analgesic, antipyretic and anti-inflammatory. The purpose of this study was to find out the effect of celecoxib on blood uric acid levels of female white mice was induced with fresh cow liver extract. Experimental animals were divided into five groups, namely the control group (-), the control group (+) and the three dose groups, respectively 0.26, 0.52 and 1.04 mg/20 g. Observations were made on 7, 14 and 21 days with the Enzymatic Photometric method. The results showed that administration of celecoxib suspension at a dose of 0.26, 0.52 and 1.04 mg/20 g did not affect blood uric acid levels when compared with controls (P> 0.05).

Formulation of Snail Slime (Achatina Fulica) Anti-Acne Emulgel using Tween 80-Span 80 as Emulsifying and HPMC as Gelling Agent

Daud, Nur Saadah, Akbar, Achnis Jum, Nurhikma, Eny, Karmilah, Karmilah

Borneo Journal of Pharmacy Vol 1 No 2 (2018): Borneo Journal of Pharmacy
Publisher : ​Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya

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Abstract

Acne is the condition of abnormal skin which is indicated by inflammation caused by the bacterial infection of Propionibacterium acnes. The natural one which can be used for the medical treatment of acne is the snail mucus (Achatina fulica). The achasin protein of it has antibacterial activity. That snail mucus was made to the emulgel form. This research has used an experimental method and the emulgel formulation used the various concentration of emulsifying agents and the gelling agent. They were Tween 80 1.76%, 2.44%, 3.12%, Span 80 2.24%, 4.06%, 5.88% and HPMC 3.5%, 4.5%, 5.5%. Other additives were propylene glycol, Methylparaben, Propylparaben, paraffin liquid, menthol, and aquadest. Those formulations were tested in physical evaluation during 4 weeks of storage in room temperature, irritation test, hedonic test, and cycling test. The organoleptic test showed that the emulgel were the milk-white color with a distinctive smell. All emulgel were homogenous, non-irritant, with emulsion type oil in water (o/w). This emulgel also met the normal skin of pH value and spread ability’s range. The emulgel viscosity shift was < 10%, with the viscosity value inversely proportional to spreadability. Formula C with 3.12% of Tween 80, 5.88% of Span 80 and 5.5% of HPMC was claimed as the most stable formula both in room temperature and after cycling test. It was also the most preferred by the panelist.

Uji Aktivitas Antioksidan Ekstrak Etanol Buah dan Biji Buah Kalangkala (Litsea angulata) asal Kalimantan Selatan

Saputri, Revita, Susiani, Eka Fitri

Borneo Journal of Pharmacy Vol 1 No 2 (2018): Borneo Journal of Pharmacy
Publisher : ​Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya

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Abstract

Free radicals are atoms or molecules, having one or more unpaired electrons. Increased production of free radicals can cause oxidative stress and cause many pathological conditions, e.g. cancers, heart diseases, and other diseases. The antioxidant can inhibit oxidative stress. Kalangkala (Litsea angulata) usually found in the South Kalimantan that can be used as an antioxidant. The study aimed to determine the antioxidant activity of ethanolic extract of Kalangkala fruits and seeds from South Kalimantan. Antioxidant activity was conducted qualitatively and quantitative uses the method DPPH. The result of the antioxidant activity of ethanolic extract of Kalangkala fruits and seeds qualitatively showed the presence of yellow spots on a purple background at Thin Layer Chromatography (TLC). The result of the activity of ethanolic extract of Kalangkala seeds quantitatively obtained IC50 value was 48.78 ppm and activity of ethanolic extract of Kalangkala fruits quantitatively obtained IC50 value was 243.14 ppm. Ethanolic extract of Kalangkala fruits and seeds from South Kalimantan has antioxidant activity.

Antibacterial Activity Test Combination of Kencur (Kaempferia galanga L) Rhizome and Sapodilla (Manilkara zapota L) Leaf Extract against Escherichia coli

Ilhani, Amanda Fadilah, Ismedsyah, Ismedsyah

Borneo Journal of Pharmacy Vol 1 No 2 (2018): Borneo Journal of Pharmacy
Publisher : ​Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya

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Abstract

Kencur (Kaempferia galanga L) rhizome and sapodilla (Manilkara zapota L) leaf are one of the plants that have been empirically proven to treat infections. Kencur rhizome contains chemical compounds such as saponins, polyphenols, flavonoids, and essential oil. Sapodilla leaf contains chemical compounds such as saponins, tannins, and flavonoids which function as antibacterial. The aim of this study was to determine the antibacterial activity of ethanol extract of kencur rhizome and sapodilla leaf ethanol extract combination against Escherichia coli bacteria. This study used an experimental method by looking at the antibacterial activity of ethanol extract of kencur rhizome and sapodilla leaf combination at a concentration ratio of 60%: 40%, 65%: 35%, 70%: 30%, 30 μg of chloramphenicol as a positive control and 70 % of alcohol as negative control. The study result showed that the combination of ethanol extract of Kencur rhizome and sapodilla leaf compared to 60%: 40%, 65%: 35% and 70%: 30%, each had an inhibitory zone against Escherichia coli of 15 mm, 13.17 mm, and 14.17 mm, chloramphenicol has an inhibitory zone of 19.83 mm and 70% alcohol does not have an inhibitory zone. This study concludes that the combination of Ethanol Extracts of Kencur Rhizome (Kaempferia galanga L) and Sapodilla leaf (Manilkara zapota L) which inhibited the growth of Escherichia coli and were more effective at a 60%: 40% comparison concentration because they were in the range of 14-16 based on Indonesian pharmacopeia standard of IV edition.

Profile of Thin-Layer Chromatography and UV-Vis Spectrophotometry of Akar Kuning Stem Extract (Arcangelisia flava)

Pratama, Mohammad Rizki Fadhil, Suratno, Suratno, Mulyani, Evi

Borneo Journal of Pharmacy Vol 1 No 2 (2018): Borneo Journal of Pharmacy
Publisher : ​Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya

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Abstract

This study aims to obtain the profile of Thin-Layer Chromatography (TLC) and Ultraviolet-Visible (UV-Vis) spectrophotometry from ethanol extract of akar kuning stems (Arcangelisia flava) from Central Kalimantan. The TLC method is used with the orientation phase of the combination of polar-non-polar solvents resulting from orientation, while ethanol is used as the solvent for UV-Vis spectrophotometers. TLC results showed the formation of 3 stains on a combination of polar solvents chloroform : methanol : water while in a non-polar solvent combination n-hexane : ethyl acetate did not show any stains. Comparison of retention factor (Rf) values show the best combination of polar solvents to separate stains at a ratio of 5 : 2 : 1, respectively. Separation in 2-dimensional TLC with polar solvents showed a similar pattern with 1-dimensional separation in the form of 3 stains. UV-Vis spectrophotometer results showed 4 main peaks with wavelength 227.2; 267.4; 345.2; and 425.3 nm, respectively. The profile of the peak formed is very similar to that shown by berberine, one of the main metabolites of akar kuning. TLC and UV-Vis spectrophotometers profiles obtained are expected to support further research using akar kuning stems, especially those from Central Kalimantan.

Pengaruh Penggunaan Media Video Pembelajaran terhadap Pemahaman tentang Komunikasi dan Konseling Obat pada Mahasiswa S1 Farmasi

Mardiati, Nurul, Restapaty, Ratna

Borneo Journal of Pharmacy Vol 1 No 1 (2018): Borneo Journal of Pharmacy
Publisher : ​Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya

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Abstract

Teaching-learning activities by lecturers are expected can use creative learning media with the use of appropriate media for the concepts to be conveyed to achieve the desired educational goals. Learning media is a tool used by lecturers to facilitate the delivery of learning materials. Learning media that can be used alone vary widely, one of which is learning video. This study aims to determine the influence of the use of video learning media on the understanding of communication and counseling drug on undergraduate students Pharmacy High School of Health Sciences Borneo Lestari Semester V Academic Year 2016/2017. This research is using the experimental method. The research design used was The Randomized Control-Group Pretest-Posttest Control Group Design. In this design, there are two groups that first randomly selected one class for the experimental group (using learning video) and one class for the control group (not using instructional video media). Sign value based on Wilcoxon test shows 0,025