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Journal of General-Procedural Dermatology & Venereology Indonesia
Published by Universitas Indonesia
ISSN : 24607991     EISSN : 24607991
The initiation of JDVI (Journal of General - Procedural Dermatology & Venereology Indonesia) was done by leading dermatologists and venereologists from Indonesia who aspired to contribute in the field of scientific publication and research. Knowledge and science continue to evolve in the field of dermatology and venereology, especially with new diagnostic methods, therapeutic and procedural approaches, and new emerging diseases.
Articles
39
Articles
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Darier-White disease: A rare genetic disorder

Cara Lynn Marie N. Chia, Ma Teresita G. Gabriel ( Department of Dermatology, Research Institute of Tropical Medicine, Muntinlupa City ) , Leilani R. Senador ( Department of Dermatology, Research Institute of Tropical Medicine, Muntinlupa City ) , Ciara Mae dela Cruz ( Department of Dermatology, Research Institute of Tropical Medicine, Muntinlupa City )

Journal of General-Procedural Dermatology & Venereology Indonesia ##issue.vol## 2, ##issue.no## 3 (2018): June 2018
Publisher : Universitas Indonesia

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Abstract

 Background: The clinical manifestation of Darier-White disease, an autosomal dominant genodermatosis, are greasy hyperkeratotic papules in seborrheic regions with nail abnormalities and mucous membrane changes due to a defective sarcoendoplasmic calcium pump. The clinical appearance and unpleasant odor in some sites of the lesions may cause psychosocial disturbances and pose a major morbidity. Case Illustration: We report a case of a 20-year old female with clinical manifestations of multiple erythematous to hyperpigmented hyperkeratotic papules, multiple flesh-colored keratotic papules with red and white longitudinal bands on dystrophic fingernails, as well as plantar pits. Skin punch biopsy was performed to support the diagnosis. Urea-containing emollients and acitretin at a dose of 0.3 mg/kg/day were prescribed for the patient. Discussion: Our case showed the classic clinical manifestations of Darier’s Disease. The skin punch biopsy result is also consistent with Darier’s disease. We provided the patient with emollients and acitretin, a systemic retinoid, which are found to be the most effective treatment for DD. While no relationship is established between Darier’s disease and other medical problems, the patient developed anxiety and social isolation due to the clinical appearance and odor, creating a negative impact on her quality of life. Conclusion: Comprehensive and holistic management should be the goals for the management of this rare genetic disorder   Keywords: acantholytic disease, Darier-White Disease, genodermatosis 

Non-standard patch test

Astri Adelia, Windy Keumala Budianti ( Department of Dermatology and Venereology, Faculty of Medicine Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta ) , Melani Marissa ( Department of Dermatology and Venereology, Faculty of Medicine Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta ) , Evita Halim Effendi ( Department of Dermatology and Venereology, Faculty of Medicine Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Jakarta )

Journal of General-Procedural Dermatology & Venereology Indonesia ##issue.vol## 2, ##issue.no## 3 (2018): June 2018
Publisher : Universitas Indonesia

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Abstract

In managing contact dermatitis, identification of the causative agent is essential to prevent recurrent complaints. Patch test is the gold standard to identify the causative agent. Nowadays, there are many patch test standard materials available in the market, but do not include all the materials that potentially cause contact dermatitis. Patch test using patient’s own products or later we refer to as non-standard materials, is very helpful in identifying the causative agents of contact dermatitis. Guidance is needed in producing non-standard patch test materials in order to avoid test results discrepancy.   Keywords: non-standard, patch test, patient’s own product

Seroprevalence of syphilis and herpes simplex virus type 2 and its association with sexual behaviour factors (a cross-sectional study among men who have sex with men in Manado, Indonesia)

Nurdjannah Jane Niode, Hendra Minarto ( Dermatovenereology Department, Faculty of Medicine, University of Sam Ratulangi/RD Kandou Hospital, Manado, Indonesia. ) , Andravita F Mitaart ( Dermatovenereology Department, Faculty of Medicine, University of Sam Ratulangi/RD Kandou Hospital, Manado, Indonesia. ) , Grace M Kapantow ( Dermatovenereology Department, Faculty of Medicine, University of Sam Ratulangi/RD Kandou Hospital, Manado, Indonesia. ) , Renate T Kandou ( Dermatovenereology Department, Faculty of Medicine, University of Sam Ratulangi/RD Kandou Hospital, Manado, Indonesia. )

Journal of General-Procedural Dermatology & Venereology Indonesia ##issue.vol## 2, ##issue.no## 2 (2017): December 2017
Publisher : Universitas Indonesia

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Abstract

Aims: This study investigated the seroprevalence and sexual risk behavior factors associated with syphilis and herpes simplex virus type 2 (HSV-2) among men who have sex with men (MSM), in Manado, Indonesia. Methods: Serum samples and questionnaires regarding their socio-demographic and sexual behaviour were collected from 60 MSM in Manado. Samples were screened for anti-HSV-2 IgG for herpes, the Venereal Disease Research Laboratory (VDRL) and the Treponema Pallidum Haemagglutination (TPHA) test for syphilis. A cross sectional method was used in this study.  Results: Of 60 MSM (median age was 20 years), 35% had homosexual orientation and 65% had bisexual orientation. First sexual intercourse of most participants (48.3%) within 16 to 18 years old. In the last 12 months, most participants (55%) had only one male sex partner. There were 63.3% and 16.7% participants performed oral and anal intercourse. About 23.3% participants used condom consistently, but only 35.7% used compatible lubricant. Seropositivity of VDRL and TPHA was detected in 5% participants and anti-HSV-2 IgG in 23.3% participants. The positive serology test for syphilis was associated with sexual intercourse mode (p= 0.001). Significant association was found between anti-HSV-2 IgG seropositivity and condom-use behaviour (p=0,028). Conclusions: The study demonstrated 5% and 23.3% positivity of serology test for syphilis and anti-HSV-2 IgG respectively. Seropositivity of syphilis was correlated with oral and anal intercourse while HSV-2 with no condom-use behaviour among MSM in Manado, Indonesia.     Keywords: syphilis, herpes simplex virus type 2, men who have sex with men, sexual behaviour, Manado  

Allergic contact dermatitis due to nickel in household detergent

Dewi Utami Putri ( Department of Dermatology & Venereology, Faculty of Medicine, Universitas Sumatera Utara, H. Adam Malik General Hospital Medan, Indonesia. ) , Irma Damayanti Roesyanto-Mahadi ( Department of Dermatology & Venereology, Faculty of Medicine, Universitas Sumatera Utara, H. Adam Malik General Hospital Medan, Indonesia. )

Journal of General-Procedural Dermatology & Venereology Indonesia ##issue.vol## 2, ##issue.no## 2 (2017): December 2017
Publisher : Universitas Indonesia

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Abstract

Allergic contact dermatitis (ACD) is a cutaneous inflammatory reaction caused by contact with specific exogenous allergen to which a person has developed allergic sensitization. Nickel was reported as one of the most common causes of ACD worldwide, particularly affecting females. It is associated with a variety of nickel-containing products, from jewelry to detergent. A 32-year-old female was presented with pruritic eruption consist of erythematous papules and vesicles on both hands and extensor forearms since 2 weeks before admission. The patient is a housewife who did handwashing clothes and kitchenware with detergent and soap every day. At first, there were erythematous papules on the right extensor forearm, then the patient wore rubber gloves to protect hands when washing. However, the lesions spread to the left extensor forearm and there were also vesicles on both hands. There was history of localized reactions to metal items, the latter one was 3 weeks ago after wearing a metal necklace. The clinical presentation were multiple erythematous papules and vesicles, erythematous and hyperpigmented macules. The patch test using Chemotechnique Diagnostics AB and square chamber showed a 2+ reaction to nickel sulphate. The patient was educated to avoid the causative allergen and treated with oral antihistamine and topical corticosteroid. The patient showed significant clinical improvement after 2 weeks.  Nickel as metal catalyst used in detergents is found in small concentration, but can lead to ACD in an already sensitized individual. The lesions persist despite the use of gloves because nickel is absorbed through rubber material.   Keywords: allergic contact dermatitis, nickel, metal catalyst, household detergent, patch test  

Efficacy of Topical Estradiol Compared to Topical Glycolic Acid for Skin Aging Treatment in Postmenopausal Women

Shannaz Nadia Yusharyahya ( dr.Cipto mangunkusumo Hospital, Jakarta, Indonesia ) , Marsha Bianti ( Dermatovenereology Department Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Diponegoro Street No. 71, Jakarta, Indonesia )

Journal of General-Procedural Dermatology & Venereology Indonesia ##issue.vol## 2, ##issue.no## 2 (2017): December 2017
Publisher : Universitas Indonesia

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Abstract

Skin aging is a complex biological process in human being, as a result from intrinsic factors (genetic, hormonal, metabolism) and extrinsic factors (UV exposure, pollution, smoking, life style). In postmenopausal women, physiologically, the amount of estrogen are decreased, causing deterioration of their skin’s appearance. Along with the changes that occur, skin care require more attention. A holistic approach can increase epidermal thickness, therefore, reducing the depth of wrinkles, as well as improving skin texture and moisture. There are various treatments available to improve skin appearance due to aging. This EBCR is aimed to compare the efficacy of topical estradiol and topical glycolic acid as skin treatment in postmenopausal women. Articles were searched through Pubmed/MEDLINE, EBSCO, and Cochrane. One randomized-controlled trial by Fuchs KO, et al was obtained and critically appraised. Based on the appraisal, study by Fuchs KO, et al is considered valid, important, and applicable. Both estradiol and glycolic acid show good efficacy and safety for postmenopausal women with signs of skin aging, however estradiol is not considered to have better efficacy than glycolic acid.   Keywords: aging, efficacy, postmenopausal, topical estradiol, topical glycolic acid

Photodermatoses in Children

Siti Nurani Fauziah, Wresti Indriatmi ( Dermatovenereology Department Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Diponegoro Street No. 71, Jakarta, Indonesia ) , Lili Legiawati ( Dermatovenereology Department Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Diponegoro Street No. 71, Jakarta, Indonesia )

Journal of General-Procedural Dermatology & Venereology Indonesia ##issue.vol## 2, ##issue.no## 2 (2017): December 2017
Publisher : Universitas Indonesia

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Abstract

Photodermatoses cover the skin’s abnormal reactions to sunlight, usually to its ultraviolet (UV) component or visible light. Etiologically, photodermatoses can be classified into 4 categories:  (1) immunologically mediated photodermatoses (idiopathic photodermatoses); (2) drug- or chemical-induced photosensitivity; (3) hereditary photodermatoses; and (4) photoaggravated dermatoses. The incidence of photodermatoses in the pediatric population is much lower than in adults, Polymorphous light eruption (PMLE) is the most common form of photodermatoses in children, followed by erythropoietic protoporphyria. Early diagnosis and investigations should be performed to avoid long-term complications. Photoprotection is the mainstay of photodermatoses management, including use of physical protection and sunscreen.   Keywords: children, photodermatoses, photoprotection, polymorphous light eruption.

Venous Ulcer

Irene Dorthy Santoso ( Dermatology & Venereology Department, Faculty of Medicine, Universitas Indonesia ) , Hanny Nilasari ( Department of Dermatology & Venereology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Hospital, Jakarta, Indonesia ) , Shannaz Nadia Yusharyahya ( Department of Dermatology & Venereology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Hospital, Jakarta, Indonesia )

Journal of General-Procedural Dermatology & Venereology Indonesia ##issue.vol## 2, ##issue.no## 2 (2017): December 2017
Publisher : Universitas Indonesia

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Abstract

Leg ulcers one common problem in the adult population to geriatric with a prevalence about 1-2%. The pattern of life which tends to be sedentary, less activity, obesity, increased the incidence of leg ulcers. The duration of healing and recurrence occurs in majority of patients contributed the decline in quality of life for patients with venous ulcers. Diagnosis, latest treatment and prevention are essential to discuss. Keywords: venous ulcer, geriatric, diagnosis, management, prevention

Pattern of pigmentation disorder in Cosmetic Dermatology Clinic H. Adam Malik General Hospital, Medan, 2012 - 2015

Nelva Karmila Jusuf ( Department of Dermatovenereology, Medical Faculty University of Sumatera Utara, RSUP H. Adam Malik Jl. Bunga Lau17 , Medan )

Journal of General-Procedural Dermatology & Venereology Indonesia ##issue.vol## 2, ##issue.no## 1 (2017): August
Publisher : Universitas Indonesia

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Abstract

Background: Abnormalities of pigmentation is a cosmetic problem which affects the overall appearance of an individual. Pigmentation disorder are caused by the increase (hypermelanosis) or the decrease (hypomelanosis) amount of melanin. Objective: To determine the pattern of pigmentation disorder in Cosmetic Dermatology Clinic H. Adam Malik General Hospital Medan in 2012-2015. Methods: A retrospective study using subjects medical records from the Cosmetic Dermatology Clinic H. Adam Malik General Hospital Medan in 2012 - 2015, presented descriptively. Results: In 2012 - 2015 the number of patients who visited the Cosmetic Dermatology Clinic were respectively 210, 228, 211, 142. Hypermelanosis were found respectively in 24.76%, 16.20%, 12.79%, 5.63%. Whereas hypomelanosis were found 18.10%, 9.21%, 8.53%, 8.45%. During 2012 - 2015 melasma was the most common disorder found among hypermelanosis group, followed by post inflammatory hyperpigmentation. Meanwhile vitiligo was the only diagnosis in hypomelanosis group. Each year most of the pigmentation disorder patients came from the age group 38-48 years old except in 2015. Women were more affected than men.  Conclusion: In 2012-2014, the largest proportion of pigmentation disorder were hypermelanosis, mostly melasma. In 2015, it was hypomelanosis with vitiligo as the diagnosis.   Keywords: pigmentation disorder, cosmetic division, retrospective  

The effectiveness of laser therapy in onychomycosis patients: An evidence-based case report

Rizky Lendl Prayogo, Evangelina Lumban Gaol, Fitri Azizah, Lusiana Lusiana, Yenny Rachmawati, Yusnita Rahman, Siti Rizny F Saldi

Journal of General-Procedural Dermatology & Venereology Indonesia ##issue.vol## 2, ##issue.no## 1 (2017): August
Publisher : Universitas Indonesia

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Abstract

Background: Onychomycosis may cause nail discoloration, thickening, nail bed separation, and other serious complications. For some cases, oral antifungal treatment is not tolerable because of its potential side effects and drug interactions. Laser therapy is considered as an alternative treatment, owing to the features of simple and effective, with only minor potential side effects. This EBCR was made to collect and appraise studies regarding the effectiveness of laser therapy for onychomycosis, and to suggest laser as an alternative treatment.Methods: Literature searching strategy was performed using Pubmed and Cochrane Library database to address the clinical problem. Keywords used were “laser” AND “onychomycosis”.Results: Seventy-nine articles were obtained from the search strategy procedure. After selection based on exclusion and inclusion criteria, and full-text availability, four relevant articles remained.Discussion: The study by Xu et al. was considered as the most valid study while compared to other three studies. This study used intention to treat analysis and had no loss of follow-up patients. Xu et al. compared mycological and clinical clearance rate between patients receiving laser, oral terbinafine, or combination of those two. It showed that laser therapy was less effective when compared to oral antifungal (Number Needed to Harm = 17).Conclusions: Laser has a lower level of effectiveness while compared to oral terbinafine as the current gold standard therapy for onychomycosis. However, laser therapy can still be used as an adjunctive therapy along with oral antifungal to achieve a better cure rate. More studies are needed to prove this hypothesis. Keywords: onychomycosis, laser therapy, effectiveness

Segmental zoster paresis

Nahla Shihab, Erdina HD Pusponegoro, Ahmad Yanuar

Journal of General-Procedural Dermatology & Venereology Indonesia ##issue.vol## 2, ##issue.no## 1 (2017): August
Publisher : Universitas Indonesia

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Abstract

Herpes zoster is often associated with neurological manifestation but less frequently associated with motoric nerve involvement. The most common motoric involvement is paresis, seen only in 1-5% of all zoster cases. This case report a 39-year-old male, with recurrent abdominal liposarcoma under chemotherapy, presented with symptoms of fever, and painful and weak right leg for 2 weeks. Vesicles eruption was seen on his right leg nine days after these symptoms occurred. Physical examination revealed groups of haemorrhagic vesicles with erythematous base on the right lower leg. Lumbosacral spine x-ray showed spondylosis with radiculopathy. Electromyography (EMG) examination revealed lower motor neuron total denervation corresponding to right L5 radix. The patient was diagnosed as herpes zoster on right L5-S1 segment, herpetic neuralgia, and segmental zoster paresis with recurrent liposarcoma under chemotherapy. He was treated with oral acyclovir 800 mg five times a day and gabapentin 300 mg twice a day.  Physical therapy and rehabilitation were started concurrently. Paresis is a rare complication of herpes zoster. Radicular pain and weakness preceded the skin lesion potentially lead to misdiagnoses. The most frequent diagnosis for patient suffering pain and weakness in the extremities is spinal disorder, such as stenosis and disc herniation. EMG can be helpful to recognise motoric involvement of herpes zoster, and preclude other diagnoses.   Keywords: herpes zoster, paresis, radicular pain