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Journal of Medicine and Health
Journal of Medicine and Health (JMH) is an open access journal (OAJ), a periodic scientific publication biannually online published on February and August; using review and screening system by peer group reviewer. JMH receives original research articles which related to medicine, health, new developing therapy from traditional medicine or herbs and developing clinical therapy. JMH also receives otiginal review articles, case report, continuing medicine and health study. Articles should be written in good English or Indonesian language.
Articles
157
Articles
Association between Histopathological Grading and Clinical Staging in Nasopharyngeal Carcinoma

Naomi, Sonya M, Dewi, Yussy A, Agustina, Hasrayati

Journal of Medicine & Health Vol 2, No 2 (2018)
Publisher : Universitas Kristen Maranatha

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Abstract

Nasopharyngeal Carcinoma (NPC) is the most common cancer in head and neck. Grading of NPC is based on keratinization, growth, and cell junction, and it can be classified into well differentiated, moderately differentiated, poorly differentiated, and undifferentiated. On the other hand, the staging of NPC based on UICC/AJCC staging system is divided into Stage I-IVC. This classification is based on TNM that is related to the ability of cancer cells to invade normal cells. This study was conducted from May to June 2017 in Oncology Clinic of Otorhinolaryngology-Head and Neck Surgery Department and Pathology Anatomy Department of Hasan Sadikin General Hospital. This is an analytical correlative study with cross sectional design. The data is collected retrospectively from medical records of patients who are diagnosed as NPC with adequate grading and staging data. Incomplete medical records, multiple carcinoma, and recurrent carcinoma are excluded from this study. We find out that among 51 samples, predominant is Stage IVB NPC (37.3%) and undifferentiated grade NPC (76.5%). Statistical analysis shows that there is no significant association between grading and staging (r=0.275; p=0.159).This study concludes that there is no association between histopathological grading and clinical staging in nasopharyngeal carcinoma.Keywords: nasopharyngeal carcinoma, grading, staging

Risk Factors of Laryngeal Carcinoma in Otorhinolaryngology-Head and Neck Division of Dr. Hasan Sadikin Hospital Bandung

Putri, Sarah A, Dewi, Yussy A, Dewayani, Birgitta M

Journal of Medicine & Health Vol 2, No 2 (2018)
Publisher : Universitas Kristen Maranatha

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Abstract

Laryngeal carcinoma is a squamous cell malignancy of larynx epithelial with the Indonesian incidence of 2.0 per 100,000 men and 0.2 per 100,000 women. The risk factors of laryngeal carcinoma include age, sex, family history, smoking habit, alcohol drink, and gastroesophangeal reflux disease (GERD)/ laryngopharyngeal reflux (LPR). This study aimed to know some risk factors for laryngeal carcinoma mentioned in Dr. Hasan Sadikin Hospital, Bandung. Hospital-based unmatched case control study was selected as the methods, involving 80 patients in Oncology Clinic of Otorhinolaryngology-Head and Neck Surgery Department, Dr. Hasan Sadikin General Hospital. The medical records of the carcinoma larynx patients was taken as a study instrument. The results were age percentage of 50-79 years old in the case group is 82.5% therefore, it increase the risk of having laryngeal carcinoma by 7.29 times. Male respondents dominate in the case group (90%) with OR =6.00. Respondents with GERD in the case group is 45%, increasing the risk 15.54 times and these results was significant (p<0.005). Other analyzed variables, such as family history, smoking history, and alcohol consumption is not significant statistically (p>0.005). This study shows the results of age, sex, and GERD/LPR are corresponding with the results with previous studies. Otherwise, the results of smoking, alcohol, and family history are not. Therefore, old age, male sex, and GERD increase the risk of having laryngeal carcinoma.

KNOWLEDGE, ATTITUDES, AND BEHAVIOR OF PARENTS TO THE METHOD OF UPBRINGING CHILDREN WHO HAVE DOWN SYNDROME IN SLB-C TUNAS HARAPAN KARAWANG

Dwinindita, Lizsa Y, Ivone, July, Supantini, Dedeh

Journal of Medicine & Health Vol 2, No 2 (2018)
Publisher : Universitas Kristen Maranatha

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Abstract

Down syndrome is a genetic disorder characterized by an excess of third chromosome in the 21st pair of chromosomes that causes the number of chromosomes to be 47. The method of parenting is a way of caring, nurturing and educating, therefore parents should have knowledge, attitude and good method of behavior parenting. The highest prevalence of Down syndrome is in West Java, which is around 50.90%. The aim of the research is to recognize the level of knowledge, attitudes, and behavior of parents to the method of upbringing children who have Down syndrome in SLB-C Tunas Harapan Karawang. The research method used in this research is descriptive, cross sectional design with research instrument in the form of questionnaire containing 30 questions. Research subjects were all parents of Down syndrome children in SLB-C Tunas Harapan Karawang with 52 respondents. The result of the research is 90,4% of respondents have good knowledge, 98,2% of respondents have good attitude, and 96,1% of respondents have good behavior. The conclusion of this research is the level of knowledge, attitude, and behavior of parents who have Down syndrome children in SLB-C Tunas Harapan Karawang generally is good.     Keywords: down syndrome, parents, upbringing

Elderly Characteristics with Frailty Syndrome by Frailty Index Questionnaire – 40 (FI - 40) at Bandung Nursing Home

Rahmadani, Ivany R, Dwipa, Lazuardhi, Pratiwi, Yuni S

Journal of Medicine & Health Vol 2, No 2 (2018)
Publisher : Universitas Kristen Maranatha

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Abstract

Frailty syndrome is a state of decreased body function, thereby increasing susceptibility to poor clinical outcomes. The risks of developing frailty syndrome increase in the elderly at Nursing Home. This study is expected to provide characteristic data of frailty syndrome as the basis for the prevention and management for the elderly. This study is conducted by using a descriptive quantitative design. The data is taken by using FI-40 questionnaire consisting of 40 questions in the elderly at Bandung done by using total sampling. There are 42(58.3%) of pre-frail and 7(9.7%) of frail elderly out of 72 data. Pre-frail prevails mostly in women (29 subjects; 69.1%) and at age of 60-69 years in 18 subjects (42.8%). Frail elderly is found mostly in women (3 subjects; 42.8%) and aged 70-79 years (3 subjects ; (42.8). The most common cause of frailty is eye and foot problems in 7(100%). The most common cause of pre-frail is the assumption of health level in 35(83.3%). This study concludes that frailty syndrome is common among the elderly and special attention must be paid to eye and foot problems.Keywords: elderly, frailty syndrome, FI-40 questionnaire, nursing home

Blood Pressure Changes on Tooth Extraction Using Local Anesthesia Contains 1:80,000 Epinephrine at Jatinangor Primary Health Care

Wijaya, Muhammad A, Hidayat, Marlianti, Sitorus, Trully D

Journal of Medicine & Health Vol 2, No 2 (2018)
Publisher : Universitas Kristen Maranatha

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Abstract

Hypertension is a systemic disorder which included as one of the disease with highest prevalence in the world, particularly in Indonesia. One problem that is commonly faced by hypertension patients is administration of local anesthetic containing epinephrine 1:80.000 that needs to be given before undergoing tooth extraction procedure in primary health care setting. Administration of anesthetics is risky because it can cause sudden blood pressure increase that may cause complications. This study aims to observe the increased of blood pressure after being given local anesthetic containing epinephrine 1:80.000. This is a descriptive quantitative study conducted in April-August 2017 in Puskesmas Jatinangor. Blood pressure data is primary data, acquired from normotension and prehypertension patients aged 18-50 year who undergoes tooth extraction procedure. Blood pressure were measured before and after given local anesthetic. Result showed that there were increase in mean systolic blood pressure as much as 3.43 mmHg. Increase in systolic blood pressure occurs from the effect of epinephrine that causes constriction of the blood vessels. It is concluded that administration of local anesthetic containing epinephrine 1:80.000 before tooth extraction procedure is relatively safe and can be considered to be used in pre-hypertension patients, but not in higher hypertension stages.

Topical Clover Flower Honey Administration Accelerated Wound Healing in Swiss Webster Mice

Kristian, Hans, Budiman, Iwan, Hasianna, Stella T

Journal of Medicine & Health Vol 2, No 2 (2018)
Publisher : Universitas Kristen Maranatha

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Abstract

 AbstractClover flower honey is a herbal therapy used as an alternative wound treatment. The objective of this study was to determine the effect of Clover flower honey in accelerating incision wound healing, enhancing reepithelization degree, increasing fibroblast density, and collagen. This was a true experimental research, using 25 mice divided into 5 groups (n=5); positive control group (feracrylum 1%), negative control group (aquadest), 100% honey group, 50% honey group, and 25% honey group. Wound healing activity was measured macroscopically with calipers, dan microscopically through pathological anatomy preparations to observe reepithelization degree and collagen density. This study showed wound incision lengths were different significantly between Clover flower honey 100%, 50%, and 25% compared to aquadest (p ≤ 0.05), and feracrylum 1% (p ≤ 0.05). Reepithelization degree, fibroblast and collagen density measurements between Clover flower honey 100%, 50%, and 25% were different significantly compared with aquadest (p ≤ 0.05), and only the 100% honey group was different significantly with feracrylum 1% (p ≤ 0.05). We concluded topical Clover flower honey administration accelerated wound healing, increased reepithelization degree, fibroblast density, and collagen degree.Keywords : wound healing, reepithelization degree, fibroblast density, collagen density, Clover flower honey

Characteristics of Mediastinal Tumors in Dr. Hasan Sadikin General Hospital, Periods of 2011-2016

Giovani, Octavianus, Agustina, Hasrayati, Djajakusumah, Teguh M

Journal of Medicine & Health Vol 2, No 2 (2018)
Publisher : Universitas Kristen Maranatha

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Abstract

Mediastinal tumors are considered to be mediastinal disease with various clinical and histopathologic presentations. In Indonesia, literatures concerning mediastinal tumors are still few. This study aims to obtain the characteristic of mediastinal tumors in Dr.Hasan Sadikin Hospital. A cross-sectional retrospective study was conducted using medical records from 2011 to 2016. All medical records with clinical diagnosis of mediastinal tumors are included, and cases with metastatic tumors from distant sites to the mediastinum, and/or incorrect histopathologic findings are excluded. We obtain data of age, gender, clinical symptoms, histopathologic finding, and staging, with total samples collected of 72. We find out that patients with mediastinal tumors are mainly over 40 years old (62.5%), especially in the 6th decade of life (23.6%), and were mostly of males (73.6%). Patients mainly had chief complaints of dyspnea (38.7%), followed by cough and typical myasthenia gravis symptoms. The most common type of mediastinal tumor is epithelial cell tumor (68.4%), and the most common stage is Masaoka-Koga stage III (37.5%). This study concludes that mediastinal tumor mainly occurs in males aged 40 years old and above, with epithelial cell tumor as the most common histopathologic findings.Keywords : characteristics; mediastinal tumor; mediastinum

Sleeping Quality Does Not Affect Blood Pressure among Elderly in Tresna Werdha Nursing Home City of Bandung

Mohani, Vani S, Nurhayati, Titing, Sari, Dian M

Journal of Medicine & Health Vol 2, No 2 (2018)
Publisher : Universitas Kristen Maranatha

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Abstract

AbstractBad sleep quality is often associated with rise in blood pressure. However, there are still differences between measurement done in elderly respondents and other age categories. Thus, the aim of this study is to determine association between quality of sleep with blood pressure among elderly in Tresna Werdha nursing home city of Bandung. This study uses analytical method with cross-section design. Respondents in this study are 51 people with elderly age category. Instruments used are Pittsburgh Sleep Quality Index (PSQI) questionnaire, mercury sphygmomanometer, and stethoscope. PSQI questionnaire is used to measure sleep quality with good sleep quality scores < 5, and bad sleep quality scores ≥ 5. Blood pressure with measurement result < 120 for systolic pressure and < 80 mmHg for diastolic pressure is categorized as normal blood pressure, and hypertension is categorized with measurement result ≥ 140 for systolic pressure and ≥ 90 mmHg for diastolic pressure.This study uses Chi-square analysis test with significance value p<0.05. Result of this study shows p = 0.113 for systolic pressure and p = 0.543 for diastolic pressure, it can be concluded that there is no association between sleep quality and blood pressure among elderly in Tresna Werdha nursing home city of Bandung. Keywords: sleeping quality, elderly, nursing home, blood pressure 

Bitter Leaves Ethanol Extract (Vernonia amygdalina) Decreases Total Cholesterol Serum Level of Hypercholesterolemic Male Wistar Rats

Hasan, Ivana C, Subroto, Hendra, Puspasari, Grace

Journal of Medicine & Health Vol 2, No 2 (2018)
Publisher : Universitas Kristen Maranatha

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Abstract

Hypercholesterolemia is an important risk factors of atherosclerosis. Bitter leaf is believed to have potency in decreasing plasma lipid. The aim of this study is to study the effect of bitter leaf ethanol extract in decreasing total cholesterol serum levels on hypercholesterolemic male Wistar rats. This is a true experimental laboratory study with complete randomized design. Antidyslipidemia effect was tested with HFF induction and Propiltiourasil 0,01% towards 30 rats which were divided into 6 groups: groups I as normal control (standard diet), groups II, III, and IV were given bitter leaf ethanol extract of 100 mg/kgBW, 200 mg/kgBW, and 400 mg/kgBW dose, group V as positive control group with Simvastatin, and group VI as negative with aquades. HFF  were given for 14 days then the study was continued for 14 days. The percentage data of the declining total cholesterol levels before and after treatments is analyzed with ANAVA, continued with LSD test. The result between group II, III, and IV with group VI shows a significant difference p<0,01. We concluded bitter leaf ethanol extract can decrease the level of total cholesterol serum of hypercholesterolmic Wistar rats.

PEER REVIEW

Team, Editorial

Journal of Medicine & Health Vol 2, No 2 (2018)
Publisher : Universitas Kristen Maranatha

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Abstract

We would like to thank our peer reviewers for the precious contributions in providing clinical, scientific, and methodological expertise for JMH Volume 2 Number 2 August 2018. We appreciate every thoughtful review of submitted manuscripts and for making important contributions to improve the scientific quality of articles published in JMH. We listed the names in alphabetical order.DR.Achadiyani,dr.,M.KesDr.rer.nat. Afiat Berbudi, dr., M.KesProf. DR. Ambrosius Purba, dr.,MS.,AIFOProf. Andreanus A. Soemardji, DEAAndri Rezano,dr.,M.Kes,PhDCherry Azaria,dr.,M.KesDecky Gunawan,dr., M.Kes,AIFODemes Chornelia Martantiningtyas,S.Si,M.ScDR.Guswan Wiwaha, dr., MMDr. dr. Hana Ratnawati ,M.Kes., PA(K)Heddy Herdiman,dr.,M.KesHendra Polii, drg., Sp.RKGJulia Windi Gunadi,dr.,M.KesJuly Ivone, dr., MKK., MPd.KedLaella Kinghua Liana,dr.,Sp.PA,M.KesDR. Meilinah Hidayat, dr., M.KesMia Kusmiati,dr.MPd.KedMonica Paotiana,dr.,M.GiziDR.Oeij Anindita Adhika,dr.,M.KesRimonta F.Gunanegara,dr.,Sp.OG,M.PdKedRoro Wahyudianingsih,dr.,Sp.PASijani Prahastuti,dr.,M.KesStella Tinia Hasianna,dr., M.Kes,IBCLCDr. Wahyu Widowati, M.Si.Yenni Limyati,dr.,Sp.KFR.,M.KesYuktiana Kharisma, dr., M.Kes