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INDONESIA
Health Notions
ISSN : 25804936     EISSN : -     DOI : -
Core Subject : Health,
"Health Notions" is a media for the publication of articles on research and review of the literature. We accept articles in the areas of health science and practice such as public health, medicine, pharmaceutical, environmental health, nursing, midwifery, nutrition, health technology, clinical laboratories, health education, and health popular.
Arjuna Subject : -
Articles 573 Documents
Both Acute and Chronic Exercise Decrease Total Cholesterol Level in Human Blood Purwanto, Bambang; Pratiwi, Wahyu N.; Abdurachman, Abdurachman
Health Notions Vol 2, No 9 (2018): September
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Original Source | Check in Google Scholar | Full PDF (107.872 KB) | DOI: 10.33846/hn.v2i9.319

Abstract

Exercise such as Diabetes dance of Persadia 1 is the evolvement of prior diabetes dance series with aerobic principle with more eccentric movement. Diabetes dance of Persadia 1 has been inspected effective for lowering fasting blood glucose, but its still unknown about its effect on blood level of total cholesterol. The aim of this research was to analyze the effect of exercise on total cholesterol level. This research was experimental study, with 16 subject of healthy housewifes and divided on 2 groups, that were exercise and control group. Exercise group was given with diabetes dance of Persadia 1 while control group have the unstructured activity. Blood level of total cholesterol (TC) has been measured after 24 hours post single bout exercise (acute-AE) and repeated exercise (chronic exercise-CE). Paired t-test analysis on both acute (AC) (p=0.005) and chronic (CC) (p=0.006) shows TC decrease significantly on control group, as well as on AE (p=0.001) and CE (p=0.001). However, TC tend to increase on CC though not significantly increase (p=0.916), while on CE tend to decrease significantly (p=0.041). This study showed that both acute and cronic exercise decrease total cholesterol level in human blood. Keywords: Interleukin-6, Total cholesterol level, Exercise
The Effect of Diaphragm Breathing Exercise To Lower Back Pain Changes of Pregnant Women in Tapa Public Health Center, Bone Bolango District Zakaria, Rabia; Tompunuh, Magdalena M.; Porouw, Hasnawatty S.
Health Notions Vol 3, No 2 (2019): February
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Original Source | Check in Google Scholar | Full PDF (71.221 KB) | DOI: 10.33846/hn.v2i2.298

Abstract

Low back pain to pregnancy is described as a pain in lumar region, on the sacrum, and can up to the feet. The pain is intermitte, and aggravated by doing activities with the same position in a long time, usually happens in 30 minutes like walking, sitting, and standing. If not handled well, bottom pain will disturb the activities of pregnant women so that it will make the life quality of pregnant women become bad. Diaphragm breathing exercise help the patients to use diaphragm well while breathing. The research type was pre-experimental design, with the design of One Group Pretest-posttest Design. The population of this research were all pregnant women located in the working area of Tapa Public Health Center. Population size were 40 people. Sample size was obtained from total population that were chosen by using purposive sampling technique. The sample size was determined by using Slovin formula which obtains 16 Respondents who fulfill Inclusion and exclusion criteria, the statistical test was by normality test using Shapiro Wilk Test. The results was that 75% respondents who suffer mild pain and 12.5% respondents who suffer moderate pain and there was an effect of giving diaphragm breathing exercise practice to changes in lower back pain to Pregnant women with p value 0.000. Expected able to enhance the society’s knowledge especially pregnant women about diaphragm breathing exercise implementation instructions in pressing the changes of lower back pain. Keywords: Diaphragm breathing, Pregnant, Lower back pain
Preparation and Characteristics of NLC Coenzym Q10 with A Combination of Hyaluronic Acid Sarifuddin, Nurhidayah; Soerarti, Widji; Rosita, Noorma
Health Notions Vol 3, No 1 (2019): January
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Original Source | Check in Google Scholar | Full PDF (234.118 KB) | DOI: 10.33846/hn.v3i1.250

Abstract

Coenzyme Q10, often also known as ubiquinone, coenzyme Q10 or Q10, is soluble in lipids and is naturally present in plants, animals and in mitochondria. Coenzyme Q10 functions as an antioxidant that can protect the body from damage caused by free radicals. Hyaluronic acid is known as a hydrophilic polymer derived from polysaccharides which has the ability to increase percutaneous penetration by changing the composition of tightly arranged stratum corneum cells to increase the permeability of the skin. Nanostructured Lipid Carrier is a modification of the SLN system, consisting of a mixture of solid and liquid lipids (oil), stabilized by aqueous surfactant solution, is one method to increase drug penetration through the stratum corneum because it has several advantages. The purpose of this study was to see the effect of adding hyaluronic acid to the characteristics of the Nanostructure Lipid Carrier (NLC) as anti aging. Examination of characteristics including organoletis, pH, particle size and polidispersity index was carried out. The results of organoleptic NLC coenzym Q10-HA examination obtained dark orange color, liquid consistency, lipid efficacy odor and soft texture. The pH measurement results of the preparation ranged from 5.05-5.23. The results of the particle size examination ranged from 267-128 nm and the particle size distribution ranged between 0.308-0.200 Keywords: Coenzym Q10, Hyaluronic acid , NLC
The Efforts to Control and Prevent Cervical Cancer through Early Detection Using the VIA Test in the East Java Provincial Health Office Zulham, Riza Muhammad; Wahyuni, Chatarina Umbul; Isfandiari, Muhammad Atoillah; Huda, Hasan
Health Notions Vol 2, No 9 (2018): September
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Original Source | Check in Google Scholar | Full PDF (224.191 KB) | DOI: 10.33846/hn.v2i9.318

Abstract

Introduction:Cervical cancer is cancer that affectthe cervix and mostly (99,7%) caused by oncogenic Human Papilloma Virus (HPV). This cancer affect women who is multipara and lack of maintaining of their reproductive health. Cervical cancer cases in East Java Province in 2017 was still high and there were about 3,013 cases. This cervical cancer requiredcontrol and prevention such as screening, finding and following-up the cervical cancer cases, increasing the life quality, and decreasing mortality rate. One of cheap and quick early detection methods for screening of cervical cancer was utilizing of the VIA test method (Visual Inspection of Acetic Acid). Objective:This research aimed to analyze and solve the problem on early detection program for cervical cancer through IVA test method in Health Office of East Java Province- Indonesia. Method:The data of cervical cancer program in 2017 was collected. The data of early detection program for cervical cancer through VIA test method was analyzed and interview was conducted on health program officer and manager of the cervical cancer program to acquire the health program issues. Afterwards, the priority of the issues found on cercival cancer program was determinedusingthe Capability Accessibility Readiness Leverage (CARL) method and the alternative problem solving was determined using NGT (Nominal Group Technique) method. Conclusion:In order to achieve the early detection of cervical cancer case through VIA test method targets/indicators, Health Office of East Java Province needed to conduct network and collaboration with all of related units on the existing cervical cancer program. Health Office of East Java Province also needed to take role actively in increasing the motivation of District Health Office so that they collected and reportedthe record of non-communicable disease surveillance datawell and on time. Keywords: Control, Prevention, Cervical Cancer, CARL, NGT
Effectiveness of Injectable Alendronat for Bone Defect due to Osteoporosis Budiatin, Aniek Setiya; Lasandara, Cantika Suci Adlina; Khotib, Junaidi; Samirah, Samirah
Health Notions Vol 3, No 1 (2019): January
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Original Source | Check in Google Scholar | Full PDF (275.692 KB) | DOI: 10.33846/hn.v3i1.291

Abstract

Alendronate is a drug of the bisphosphonate group used for the treatment and prevention of osteoporosis in postmenopausal women. However, when given orally, alendronate can cause indigestion and osteonecrosis of the jaw. It also has a poor bioavailability. Taking these disadvantages into account, an injection formulation of alendronate was created in this study to act on the site locally. Beside alendronate, the injection also contains bovine hydroxyapatite and gelatin as alendronate carriers. Both, besides being able to act as carriers, are also able to reduce bone damage caused by osteoporosis. The aim of this study was to determine the effectiveness of alendronate injection for fractures caused by osteoporosis in mouse models that were ovariectomized. The parameters used in this study were ALP concentration in blood and bone radiology. The results of ALP concentration showed that there were no significant differences in each group. The average ALP concentration of the negative control group was 277.67 ± 46.090, in the positive control group 270.33 ± 189.716, in the BHA-Gel group 406.33 ± 212.547 and in the BHA-Gel Alendronate group 325.00 ± 73.750. Bone radiology results and macroscopic observations still showed bone defects in each group.Yet in the negative control group, the BHAGel-Alendronate group and the BHA-Gel group, bone defects were almost entirely ameliorated. On the contrary, bone defects were still present in the positive control group. Based on the results obtained, it was shown that the injection of alendronate has not been shown to significantly overcome osteoporosis fractures. Keywords: Osteoporosis, Alendronate, Ovariectomy, Bovine hydroxyapatite, Gelatin
Preparation and characterization of BSA-loaded Chitosan Microspheres Hendradi, Esti; Sari, Retno; Anggai, Rifka Anggraini
Health Notions Vol 2, No 9 (2018): September
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Original Source | Check in Google Scholar | Full PDF (255.339 KB) | DOI: 10.33846/hn.v2i9.317

Abstract

Proteins are unstable molecules because of their complex structure and easily degraded by enzymatic systems. Biodegradable microspheres have been used in protein delivery system. Bovine serum albumin was chosen as a model protein. Chitosan/tripolyphosphate microparticles have already been used to encapsulated BSA. The aim of this work was to microencapsulate these protein-CS/TPP by ionic gelation and freeze-drying. The morphology, particle size, and encapsulation efficiency of the prepared microspheres were investigated. The results revealed that the microspheres exhibited good sphericity with ranged in size from 2.25 to 2.73 µm. The study found that the moisture content of microspheres was 2.8%, the encapsulation efficiency of BSA in CS-TPP microspheres ranged from 88.14 to 96.25%. The results suggested that iontoropic gelation method will be an effective method for fabricating chitosan microspheres for delivery of protein.. Keywords: Microspheres, BSA, Ionic Gelation
Physical Condition of Dig Well and Incidence of Diarrhea in Infants at The Working Area of Kabila Community Health Center Badjuka, Bun Yamin M.; Hiola, Tumartony Thaib
Health Notions Vol 3, No 1 (2019): January
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Original Source | Check in Google Scholar | Full PDF (237.438 KB) | DOI: 10.33846/hn.v3i1.275

Abstract

Dig well is one of the clean water supply sources for the society in the countryside, and urban areas. Dig well provides water originating from the soil layer that is relatively close with ground level, therefore susceptible to contamination through seepage originating from human waste, animals, or for domestic household needs. Dig well as clean water source must be supported by construction conditions, location conditions to build a dig well, this thing is needed so that the quality of dig well’s water is safe according to the rules set. The research purpose is to know the physical condition of dig well with incidence of diarrhea in infants at the working area of Kabila Community Health Centre Bone Bolango District. This research used quantitative method, the research instrument uses observation sheet and questionairres to measure the physical condition of dig well. The result show that there was a significant effect between dig well lip height variable, wall of the dig well, septic tank distance with dig well by the incidence of diarrhea in infants. For the variable of dig well floor and closing condition of dig well obtains the result that there was no influence with the incidence of diarrhea in infants. Keywords: Physical condition, Dig well, Diarrhea
Knowledge, Attitudes and Application of Child Safety by Families in Karunrung Village, Rappocini, Makassar Baharuddin, Baharuddin; Nasrullah, Nasrullah; Muhasidah, Muhasidah; Angriani, Sri
Health Notions Vol 2, No 9 (2018): September
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Original Source | Check in Google Scholar | Full PDF (100.857 KB) | DOI: 10.33846/hn.v2i9.316

Abstract

Preliminary studies through observation and interviews of 10 parents in the Karunrung Village showed that 6 out of 10 children under five had an accident. This study aims to analyze the relationship between knowledge and attitude with the application of Child Safety, using a cross sectional design. The research subjects were 62 families with children aged 6 months to 6 years, who were selected by total sampling technique. Data were collected through the questionnaire questionnaire, then analyzed using Chi square test. The results showed that the application of Child Safety was determined by family knowledge and attitudes. Keywords: Knowledge, Attitude, Family, Child safety
Correlation Between History of ISTC Training on Independent Practicing Doctor With Discovery of TB Suspected Children in Surabaya City Jatu, Madu Puspita Nuansa; Syahrul, Fariani
Health Notions Vol 2, No 9 (2018): September
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Original Source | Check in Google Scholar | Full PDF (208.33 KB) | DOI: 10.33846/hn.v2i9.303

Abstract

The burden of Tuberculosis in children cases in the world is unknown due to the lack of diagnostic tools that are "child friendly" and the inadequacy of recording and reporting systems. TB findings in East Java province is second only to west java and the highest number of cases is in Surabaya. The purpose of this study was to analyse the relationship between history of ISTC training with the discovery of TB suspected Children. This research was done with case control design. The case samples were 14 doctors who found suspected TB in children and control sample that was 56 doctors which did not find suspected TB in children. Sampling technique was simple random sampling. Data analysis using Odds Ratio (OR) and 95% CI. The results of the analysis showed that OR value = 5.222 (95% CI 1.470
Optimation Ca-Alginate Beads as Drug Reservoir in the Patch System for Model AntiInflammatory Drug Hendradi, Esti; Isnaeni, Isnaeni; Mahmudah, Rifaatul
Health Notions Vol 2, No 9 (2018): September
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Original Source | Check in Google Scholar | Full PDF (328.375 KB) | DOI: 10.33846/hn.v2i9.320

Abstract

The aim of this study was to optimize the use of Ca-Alginates beads as a drug reservoir in the patch system with and without freeze-drying process. Meloxicam, an anti-inflammatory non-steroidal drug, was used as a drug model. Ca-alginate beads were prepared by ionic gelation method using polymer alginate and cross-linker CaCl2. The beads were evaluated for its melting temperature, FTIR spectra, and entrapment efficiency. The FTIR study showed the loss of guluronic peaks of alginate caused by a cross-linking process with Ca2+, characteristics peaks of meloxicam still appeared indicating the compatibility of the drug with the polymers used. The using Ca-alginate beads without freeze-drying process as a drug reservoir resulted in a very wet patch that was difficult to dry, cracked surface, and pharmaceutically not acceptable. Meanwhile, patch using Ca-alginate beads with the freezedrying process as a drug reservoir demonstrated satisfactory characteristics with minimum weight variation among the patches that lead to giving uniformity in the drug content. Keywords: Ca-alginate, Freeze-dry, Patch, Meloxicam, Transdermal delivery

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