cover
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kab. sleman,
Daerah istimewa yogyakarta
INDONESIA
Journal of Pharmaceutical Sciences and Community
ISSN : 16935683     EISSN : 25277146     DOI : -
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community / J Pharm Sci Community) firstly published in 2003, is a peer-reviewed, open access scientific journal that publishes research articles, review articles, as well as short communication in various pharmaceutical fields, including Pharmaceutical Technology and Pharmaceutics, Pharmaceutical Analysis, Medicinal Chemistry, Pharmacology and Toxicology, Pharmaceutical Biology, Community Pharmacy, and Clinical Pharmacy.
Articles 104 Documents
KAJIAN FAKTOR DEMOGRAFI TERHADAP KEPUASAN PASIEN JAMINAN KESEHATAN NASIONAL PADA FASILITAS KESEHATAN TINGKAT PERTAMA Christasani, Putu Dyana; Satibi, Satibi
Journal of Pharmaceutical Sciences and Community Vol 13, No 1 (2016)
Publisher : Sanata Dharma University

Show Abstract | Original Source | Check in Google Scholar | Full PDF (348.051 KB) | DOI: 10.24071/jpsc.131127

Abstract

The National Health Insurance (JKN), an Indonesian health care system, has been organized by BPJS Kesehatan using health care assurance mechanism. JKN system gave its service in collaboration with the existing health facilities throughout Indonesia. Primary health facilities named Puskesmas and Klinik Pratama, were playing role as the gate keeper of JKN system in order to provide basic health services optimally. The JKN participants’ satisfaction could be used as the indicator for measuring the success rate of the JKN system. The patient demographics was being one of several factor affecting the JKN participants’ satisfaction. This study aimed to examine the relationship between patient demographics and JKN participants’ satisfaction in Puskesmas and Klinik Pratama located in Sleman, Bantul and Yogyakarta city. This research performed the descriptive analytic using cross sectional survey design. The patients’s demographics examined in this study were patients’ age, patients’ gender, patients’ education, patients’ employment, patients’ income, and membership status. The data taken quantitatively using questionnaires and equipped with qualitative data from interviewing the patients to obtain all the possible findings in the field. Sampling techniques for primary health facilities was performed by random sampling with total sample of 55 health facilities and purposive sampling with a total sample of 150 respondents. Data were analyzed using Chi-Square method to obtain the relationship between patient demographics and JKN participants’ satisfaction. The results showed that patient’s employment, patient’s income, and membership status were significantly related to the JKN participants’ satisfaction in Puskesmas and Klinik Pratama.
KADAR HbA1c DAN RASIO LIPID PADA WANITA DEWASA DENGAN OBESITAS SENTRAL Sudaryanto, Lisa; Ventora, Laurensius Imus; Fenty, Fenty
Journal of Pharmaceutical Sciences and Community Vol 12, No 2 (2015)
Publisher : Sanata Dharma University

Show Abstract | Original Source | Check in Google Scholar | Full PDF (269.616 KB) | DOI: 10.24071/jpsc.122134

Abstract

Central obesity was accumulation of fat in the abdominal region. Many studies showed correlations between central obesity and cardiovascular diseases, e.g. diabetes and dyslipidemia.  This study was conducted to know the difference between HbA1c and lipid profil between the women with and without central obesity. This study was an analytic observational study with cross-sectional design. Subjects of 52 respondents were healthy adult women staff in campus I, II, III Sanata Dharma University in Yogyakarta and selected using purposive sampling technique. The data of waist circumference, pelvic/hip circumference, HbA1c and lipid profile were collected among the subjects and analyzed with computer with 95% confidence interval. The results of this study showed HbA1c levels and lipid profile were different between the women with and without central obesity, although the difference was not statistically significant.
EFEK PROTEKSI DEKOKTA KULIT ALPUKAT PADA HEPAR TIKUS TERINDUKSI KARBON TETRAKLORIDA Hendra, Phebe; Liong, Paramita; Putri, Brigita Wina Rosari; Fransiskus, Angeline Syahputri; Andriani, Fransisca; Putriati, Asih; Eviani, Theresia
Journal of Pharmaceutical Sciences and Community Vol 13, No 2 (2016)
Publisher : Sanata Dharma University

Show Abstract | Original Source | Check in Google Scholar | Full PDF (476.886 KB) | DOI: 10.24071/jpsc.132188

Abstract

The decoction of avocado peels was tested for their hepatoprotective activity against carbon tetrachloride-induced hepatotoxicity in rat.  The rats were treated with the decoction of avocado peels at doses of 363; 762, 1600 mg/kg per oral once in a day for 6 days and carbon tetrachloride (2 mL/kg) was given on the 7th day. Different groups of rats were given water decoction of avocado peels at a dose of 363; 762, 1600 mg/kg and after 6 hours received carbon tetrachloride (2 mL/kg), respectively. The degree of protection was measured by using biochemical parameters like serum transaminase, alkaline phosphatase and albumin. From these results it suggested that the decoction of avocado peels 762, 1600 mg/kg for 6 hours has a potent hepatoprotective action upon carbon tetrachloride-induced hepatic damage in rats.
PEMANFAATAN EKSTRAK TERSTANDARDISASI DAUN SOM JAWA (Talinum paniculatum (Jacq.) Gaertn) DALAM SEDIAAN KRIM ANTIBAKTERI Staphylococcus aureus Setyani, Wahyuning; Setyowati, Hanny; Ayuningtyas, Dewi
Journal of Pharmaceutical Sciences and Community Vol 13, No 1 (2016)
Publisher : Sanata Dharma University

Show Abstract | Original Source | Check in Google Scholar | Full PDF (659.106 KB) | DOI: 10.24071/jpsc.131139

Abstract

Infectious diseases have been the leading cause of morbidity and mortality because of the widespread antibacterial resistance due to existing drugs. Thus, the discovery and development of new antimicrobial agents, especially from natural resources is important to promote the human health. This research aimed to examine the antibacterial activity of som jawa (Talinum paniculatum (Jacq.) Gaertn.) standardized extract thus their application into cream. Extraction was done by remaceration method, then followed by phytochemical investigation to obtain the active ingredients inside extract. The result of this research showed that both som jawa standardized extract and their formula cream had antibacterial activity towards Staphylococcus aureus. This formula cream was potential as alternative herbal medicine for skin infection caused by Staphylococcus aureus.
FRAKSI ETIL ASETAT KULIT BATANG FALOAK (Sterculia quadrifida R.Br ) MENGINDUKSI APOPTOSIS DAN SIKLUS SEL PADA SEL KANKER PAYUDARA T47D Rollando, Rollando; Prilianti, Kestrilia Rega
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 14, No 1 (2017)
Publisher : Sanata Dharma University

Show Abstract | Original Source | Check in Google Scholar | Full PDF (568.506 KB) | DOI: 10.24071/jpsc.141557

Abstract

Faloak (Sterculia quadrifida R.Br) is one source of bioactive compounds that could be developed as chemotherapeutic agent. Empirically East Nusa Tenggara people use boiled water of faloak bark as a cure for hepatitis (types A, B, and C), and gastroenteritis. This study was performed to test anticancer activity fraction of n-hexane, ethyl acetate, ethanol, and methanol of ethanolic extract from faloak stem bark for the type of breast cancer cell line T47D, and normal cell types Vero using cytotoxic 3- (4,5-dimetilazol- 2-yl) -2,5-difeniltetrazolium bromide (MTT) test method. Ethanolic extract was subjected to column chromatography using different solvents polarity level as n-hexane, ethyl acetate, ethanol, and methanol. Testing the cytotoxic effects using the MTT assay in T47D breast cancer cells and normal Vero cells with EC50 parameter. Ethyl acetate fraction in inducing apoptosis and cell cycle modulation was observed with flowcytometry method. The test results cytotoxic fraction indicating the fraction of ethyl acetate has the lowest activity with EC50 of 24.88 μg/mL and selectivity index of 15.58. Ethyl acetate fraction effects an accumulation of cells in S phase (27.43%) in breast cancer cells T47D which is able to induce apoptosis. These results demonstrate that the ethyl acetate fraction can be developed as a chemotherapeutic agent in improving the effectiveness of breast cancer treatment.
DAYA HAMBAT MINYAK ATSIRI DAN EKSTRAK LIMBAH SISA DESTILASI RIMPANG KUNIR PUTIH (Kaempferia rotunda L.) TERHADAP PERTUMBUHAN Candida albicans ATCC 10231 Astutiningsih, Christina; Octaviani, Ratih; Suratiningsih, Sri
Journal of Pharmaceutical Sciences and Community Vol 11, No 1 (2014)
Publisher : Sanata Dharma University

Show Abstract | Original Source | Check in Google Scholar | Full PDF (795.15 KB) | DOI: 10.24071/jpsc.11181

Abstract

Abstract: White turmeric rhizome contains alkaloid, saponin, flavonoid, polifenol, and essential oils. The purpose of this research is to determine the antifungal activity of essensial oil and residual destillation of white turmeric rhizome against Candida albicans. Essential oils of white turmeric rhizome isolated by steam distillation method, the extraction of waste with soxhletasimethod. Antifungal activities were investigated by the paper disc method method. The test results showed antifungal activity of essential oil of white turmeric rhizome in different concentrations (0.75, 1, 2, and 2.25%) were 0.0 ; 0.736 ; 0.894 ; 1.041 cm. The antifungal activities of the residual distillation of extract (2.25, 2.5, 3, and 4%) were 0.0, 0.674, 0.743 and 0.874 cm. Therewas a difference of the zone of inhibition of Candida albicans growth between essential oils and residual distillation of white turmeric rhizome.Keywords: White turmeric, Candida albicans, essential oils, extract of waste, inhibiton.
FORMULASI SEDIAAN ORALLY DISINTEGRATING TABLET ATENOLOL DENGAN SODIUM STARCH GLYCOLATE SEBAGAI SUPERDISINTEGRAN Rani, Karina Citra; Parfati, Nani; Putri, Jessica Wangsa
Journal of Pharmaceutical Sciences and Community Vol 14, No 1 (2017)
Publisher : Sanata Dharma University

Show Abstract | Original Source | Check in Google Scholar | Full PDF (529.503 KB) | DOI: 10.24071/jpsc.141564

Abstract

Atenolol, a competitive beta (1)-selective adrenergic antagonists, has been widely used in hypertension therapy. Administration of conventional tablets of atenolol has limitation due to patient compliance in geriatric patients. Formulation of atenolol as orally disintegrating tablet (ODT) can improve the effectiveness of the drug and patient compliance in hypertension therapy. The objective of this study was to formulate orally disintegrating tablet of atenolol using sodium starch glycolate as superdisintegrant in two different concentrations (10% and 20%). Orally disintegrating tablets (ODT) of atenolol without superdisintegrant were used as a control in this study. It was found that orally disintegrating tablets (ODT) of atenolol which used 10% sodium starch glycolate have better wetting time (9.33±0.58 seconds), disintegration time (15.48±1.16 seconds), in vitro dispersion time (24.00±1.00 seconds), and dissolution efficiency (95.23±0.14 %) than orally disintegrating tablet (ODT) which used 20% sodium starch glycolate.
PENGARUH WAKTU PROTEKSI INFUSA BIJI Persea americana Mill. TERHADAP HEPAR DAN GINJAL TIKUS TERINDUKSI KARBONTETRAKLORIDA Setiawan, Lydia; Permatasari, Inneke Devi; Hendra, Phebe
Journal of Pharmaceutical Sciences and Community Vol 11, No 1 (2014)
Publisher : Sanata Dharma University

Show Abstract | Original Source | Check in Google Scholar | Full PDF (509.898 KB) | DOI: 10.24071/jpsc.11168

Abstract

Abstract: The aim of this research is to investigate the protective activity of the infusion of seed of Persea americana Mill. (IBPA) against carbon tetrachloride-induced hepatotoxicity and nephrotoxicity in rats. Healthy rats were weighed and randomly divided into 6 groups of 5 animals in each. Group 1 were treated with olive oil (2ml/kg, i.p) as negative control. Group 2 received carbon tetrachloride (2 ml/kg, i.p.). Group 3 received IBPA 360.7 mg/kg once daily for 6 hours (control of dose IBPA). Group 4-6 received IBPA at doses 360.7 mg/kg orally once for 1, 4 and 6 hours respectively received treated carbon tetrachloride. Blood sample from all groups was obtained by sinus orbitalis for the estimation serum transaminase and creatinine. The pretreatment 1,4 and 6 hours of infusion of seed of Persea americana Mill. has a potent protective activity upon carbon tetrachloride-induced hepatic and nephron damage in rats.Keywords: Persea americana Mill., infusion, protective, carbon tetrachloride
PEMAHAMAN MASYARAKAT DESA PERERENAN, KECAMATAN MENGWI, KABUPATEN BADUNG, BALI TENTANG BOREH-ANGET Hartayu, Titien Siwi; Widiasih, Ketut Ary
Journal of Pharmaceutical Sciences and Community Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Show Abstract | Original Source | Check in Google Scholar | Full PDF (89.508 KB) | DOI: 10.24071/jpsc.9273

Abstract

Abstract : Boreh-anget is one of Bali traditional medicines used by the ancient people of Bali to warm their body and it is believed that Boreh-anget could be used for pain relieves, improving blood circulation reduces rheumatic pain, and fever. This study is aimed to identify knowledge of recent generation in Bali about Boreh-anget, including what are the ingredients of it, how to make it, how to use it, and what benefit by using it. This study was conducted at Pererenan village, Mengwi, Badung Bali where is most all of people there using Boreh-anget. This study is non-experimental, descriptive qualitative approach, using purposive sampling. There are 78 participants with age ranging form 26 – 60 years old involve in this study. Data are collected using questionnaires and supported by in-depth interview among a view participants, and then the data are analyzed using enumerative methods. Results of the study show that 76.3% of participants knew about the ingredients of Boreh-anget, 92.6% of participants knew how to make Boreh Anget, 80.3% of participants knew how to use Borehanget and 78.0% of participants knew the benefit of using Boreh-anget. Conclusions of this study is that recent generation in Pererenan, Mengwi, Badung, Bali still have a high level of knowledge about Boreh-anget.Keyword: Boreh-anget, tradisional-medicines, Bali, traditional ingredient
REVIEW: PELUANG MAHKOTA DEWA SEBAGAI ANTIKANKER Hendra, Phebe
Journal of Pharmaceutical Sciences and Community Vol 9, No 2 (2012)
Publisher : Sanata Dharma University

Show Abstract | Original Source | Check in Google Scholar | Full PDF (117.574 KB) | DOI: 10.24071/jpsc.9278

Abstract

Abstract: In order to be used in formal health care systems, medicinal plants have to be safe and display promising pharmacological effects. Mahkota dewa is well known as a traditional medicine in Indonesia. In folk medicine, its fruits and leaves are used to relief cancer, impotency, hypoglycemic, hypotensive, antirheumatic, liver and kidney disorders and skin disorders. According to pharmacology and toxicology studies especially on cytotoxic effects, mahkota dewa has anticancer activity. However, further studies will be required to establish the cell target foranticancer treatment.Key words: mahkota dewa, anticancer, cytotoxic

Page 1 of 11 | Total Record : 104