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Althea Medical Journal
Articles by issue : Vol 3, No 4 (2016)
30
Articles
Treatment Evaluation of Melasma Patients in Dr. Hasan Sadikin General Hospital Bandung in period of 2013–2014

Sabila, Ayu Adzani, Hindritiani, Reti, Luftimas, Dimas Erlangga

Althea Medical Journal Vol 3, No 4 (2016)
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Abstract

Background: Melasma is hyperpigmentation of the skin especially located on face exposed to the sunlight. This condition was characterized by brown to gray-brown macula with irregular border. Difficulties in treatment of melasma arise from high tendency for relapse, expensive cost, and high risk of side effects such as erythema, sores, scales, and acne eruption. Study about evaluation of melasma therapy in Dr. Hasan Sadikin General Hospital Bandung have not ever been done before. Therefore, this study was conducted to evaluate therapy of melasma in the Policlinic of Dermatology and Venereology, Dr. Hasan Sadikin General Hospital Bandung.Methods: This study was retrospectively descriptive. Data were obtained from the new melasma patient medical records of Policlinic of Dermatology and Venereology of Dr. Hasan Sadikin General Hospital Bandung in period of January 2013–2014. Sampling method used in this study was total sampling. Treatments of melasma were evaluated by using Melasma Area Severity Index (MASI) score. Collected data were processed and presented in frequency distribution and percentage.Results: The most used topical drugs were combination of hydroquinone and tretinoin, and all of patients received sunblock. Most frequent time interval was two weeks (30.8%). The most common side effect was erythema (10 out of 22). Decreased MASI score was discovered in 48.1% and the most decreased category was mild (14 out of 25). Conclusions: The very common topical drugs used are hydroquinone and tretinoin. The side effect of the treatment is Erythema. The decreased MASI score is mild. [AMJ.2016;3(4):610–5]DOI: 10.15850/amj.v3n4.947

Clinical and Histopathological Characteristics of Psoriasis in Dr. Hasan Sadikin General Hospital Bandung from 2009 to 2013

Hermawan, Willy Chandra, Aminah, Hermin, Sandiono, Dendi

Althea Medical Journal Vol 3, No 4 (2016)
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Abstract

Background: Psoriasis is a chronic inflammatory skin disease characterized by alterations in epidermal growth and differentiation. Its primary cause remains unknown, and its clinical and histopathological characteristics sometimes change from time to time. The study aimed to reveal the clinical and histopathological characteristics among psoriasis patients in Dr. Hasan Sadikin General Hospital Bandung.Methods: This study involved 162 medical records of psoriasis patients who visited the Department of Dermato-Venereology and 40 medical records of psoriasis patients who visited the Department of Pathological Anatomy of Dr. Hasan Sadikin Hospital, from 2009 to 2013. Medical record data were collected to describe the patient’s clinical and histopathological characteristics of psoriasis. The collected data were analyzed by frequency distribution.Results: From the clinical medical records, the characteristics found among the psoriasis patients were: 14 (8.6%) having familial history, 160 (98.8%) having reddish plaque, 155 (95.7%) having silvery scale, 40 (24.7%) having pustules, 6 (3.7%) having positive Auspitz sign, 48 (29.6%) having nail involvement, and 20 (12.4%) having tongue involvement. In addition, from the histopathological medical records, the characteristics of epidermis among the psoriasis patients found were: 36 (90%) having hyperkeratosis with parakeratosis, 39 (98%) having rete ridge elongation and/or acanthosis, 35 (88%) having Munro’s microabcess and/or micropustules of Kogoj, 15 (38%) having thin stratum granulosum, and 30 (75%) having blood vessels dilatation.Conclusions: In psoriasis, the most common clinical characteristics are reddish plaque while the most common histopathological characteristics are elongation of the rete ridges and/or acanthosis. [AMJ.2016;3(4):556–61] DOI: 10.15850/amj.v3n4.938

Level of Dependency Based on Barthel and Lawton Score in Older People Living in Panti Werdha, Ciparay

Diyanto, Rizky Nurwan, Moeliono, Marina A., Dwipa, Lazuardhi

Althea Medical Journal Vol 3, No 4 (2016)
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Abstract

Background: The population of older people continues to increase. Thus, many kinds of health-related problems can occur, such as a decrease independence level in performing activities of daily living (ADL) which can be assessed by using Barthel and Lawton index. Barthel index assesses basic ADL such as mobility function, continence, and self-care. Lawton index assesses instumental ADL that are a person’s ability to use tools and face other people. There are no data available reflecting the dependency of the older people at Panti Werdha, Ciparay . This study aimed to observe the level of dependence of the older people in Panti Werdha using Barthel and Lawton index.Methods: This study was a descriptive study and was conducted at Panti Werdha, Ciparay from September to November 2015 using the total population. The level of dependence in the older people was assessed by Barthel and Lawton index. Barthel index was divided into independent, mild dependent, moderate dependent, severe dependent, and totally dependent. Lawton index was divided into independent, low dependent, high dependent, and totally dependent.Results: A total of 144 older people participated as respondents in this study. Based on the Barthel index score, it showed that 51.4% of the subjects were dependent. As for the Lawton index scor¬¬e, it showed that 81.2% of the subjects were dependent.Conclusions: Most of the older people in Panti Werdha, Ciparay are categorized as dependent, where they will need help in performing basic and instrumental ADL. [AMJ.2016;3(4):493–8] DOI: 10.15850/amj.v3n4.929

Characteristics of Renal Cell Carcinoma in Dr. Hasan Sadikin General Hospital Bandung, 2010–2014

Putra, Dicky Suryana, Suryanti, Sri, Sihombing, Aaron Tigor

Althea Medical Journal Vol 3, No 4 (2016)
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Abstract

Background: Data characteristics for renal cell carcinoma are mostly derived from developed countries. However, data from developing countries, specifically in Indonesia have not been fully described. This study aimed at describing renal cell carcinoma (RCC) characteristics based on age, gender, and histopathology type in Dr. Hasan Sadikin General Hospital Bandung.Methods: This was a descriptive study conducted in August–October 2015. The data were collected from histopathology medical records of patients who had been diagnosed with RCC at Department of Pathology Anatomy Dr. Hasan Sadikin General Hospital Bandung, from 2010 to 2014. Total sampling was used as sampling method. Only RCC records that had complete variables; which were age, gender, and histopathological type; included in this study.Results: There were 25 cases of renal cell carcinoma discovered in this study, 17 cases discovered in men and 8 cases discovered in women. The histopathology type found in this study was clear cell renal cell carcinoma (12 cases), papillary renal cell carcinoma (8 cases), chromophobe renal cell carcinoma (3 cases), and carcinoma of the collecting ducts of bellini (2 cases). There were no cases found below the age range 2–29 years old and above the age range 70–79 years old.Conclusions: Men have higher incidence than women with the ratio of 2:1. Peak incidence is found on the age range 50–59 years old. The most common histopathology type is clear cell renal cel carcinoma.[AMJ.2016;3(4):644–8] DOI: 10.15850/amj.v3n4.953

Correlation between Substance Use and Anxiety-Depression Spectrum among Senior High School Students in Bandung

Samjunanto, Achmad, Saputra, Lucky, Ekowati, RA. Retno

Althea Medical Journal Vol 3, No 4 (2016)
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Abstract

Background: Both substance use and anxiety-depression spectrum are the problem that currently faced by adolescents especially among Senior High School students. Moreover, there is a high comorbidity between both problems. This study was conducted to discover the substance use’s prevalence and to find out anxiety-depression spectrum proportion among adolescent, and more importantly to determine whether there is correlation between both variables.Methods: During October–November 2013, four hundred and fifty two students from five Senior High Schools located in Karees Sub-District, Bandung were included in this cross-sectional analytic study. Among whom, only 425 students filled the questionnaire properly. Data were collected using Kessler-10 (K10) to explore anxiety-depression spectrum and addiction severity index lite version (ASI-Lite) to identify substance use. The correlation between both variables was analyzed by Gamma correlation test.Results: The study revealed that there were 93 (21.9%) students that used substance. In addition, there were 244 students (57.4%) that screened as having anxiety-depression spectrum. Statistical analysis, according to Gamma correlation test, showed that there was a weak correlation between alcohol use and anxiety-depression spectrum (p=0.041; r=0.316). The remaining substances gave no statistically significant result (p>0.05). Conclusions: There is a high prevalence in substance use and psychological distress in anxiety-depression spectrum among high school student. In addition, alcohol is the only substances that correlated with anxiety-depression spectrum. [AMJ.2016;3(4):583–9] DOI: 10.15850/amj.v3n4.943

Spatial Ability Differences in Athletes and Non-Athletes

Cynthia, Jessica, Lubis, Leonardo, Vitriana, Vitriana

Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Althea Medical Journal

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Abstract

Background: Cognitive processes, specifically spatial abilities, are responsible for integration of daily activities. Many factors contribute to the plasticity of the brain which, furthermore, alter the spatial ability. Physical activity, which can be further grouped into sport and exercise, is a modifiable factor that enhances the cognitive processes through a divergent mechanism. This study aimed to gain further understanding on whether sport differs from exercise in altering spatial ability in athletes and non-athletes.Methods: This observational study compared the spatial ability score of athletes of Indonesia National Sport Comitte (Komite Olahraga Nasional Indonesia, KONI) in West Java (n= 21) and non-athletes (n= 21). Sampling were performed using stratified random technique and data were collected between August and October 2015 which included spatial scores and demographic of subjects.Results: The difference in spatial scores between athletes and non-athletes were not significant (p=0.432).Conclusions: This study suggests an insignificant difference in spatial ability in athletes performing sport and non-athletes performing exercise. Hence, the cognitive component skills in sport experience do not alter the spatial ability. [AMJ.2016;3(4):533–7] DOI: 10.15850/amj.v3n4.934

Correlation between Sperm Motility and Morphology in the Success Rate of in Vitro Fertilization Procedure

Ramadhan, Praditya Virza, Rezano, Andri, Permadi, Wiryawan

Althea Medical Journal Vol 3, No 4 (2016)
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Abstract

Background: In vitro fertilization (IVF) is one of the assisted reproductive technology that has been used in treating infertility. Unfortunately, not every IVF procedure achieves 100% success in fertilizing the oocyte. It has been studied that the percentage of normal motile sperm and percentage of normal sperm morphology play a key role in this process. This study was conducted to evaluate correlation between sperm motility and morphology in the success rate of IVF. Methods: This study was an observational analytic involving medical records of infertile couples who were treated by IVF procedure in Dr.Hasan Sadikin General Hospital Bandung in 2009–2014. The variables that were used in this study were percentage of sperm motility, percentage of sperm morphology and fertilization rate.The collected data was analyzed using nonparametric Mann Whitney test and Spearman correlation test.Result: This study showed that there was a significant difference between the fertilization rate group and sperm motility (p=0,048) but there was no significant correlation between motility and the entire fertilization rate (p=0,319). This study also indicated that there was no significant difference between fertilization rate group and sperm morphology (p=0,232) and there was no significant correlation between sperm morphology and fertilization rate (p=0,720).Conclusions: Motility might has a role in determining the success rate of in vitro fertilization; meanwhile morphology does not have any role in determining the success rate of in vitro fertilization. [AMJ.2016;3(4):520–5] DOI: 10.15850/amj.v3n4.957

Characteristics of Anterior Segment Dysgnesis in Pediatric and Strabismus Ophthalmology Unit at Cicendo Eye Hospital 2012-2014

Ramadanti, Sarah Nurul, Irfani, Irawati, Khairani, Astrid Feinisa

Althea Medical Journal Vol 3, No 4 (2016)
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Abstract

Background: Developmental anomalies in congenital anomalies cause malformation, such as Anterior Segment Dysgenesis (ASD). Disorder in maturation of anterior segment of the eye occurs in ASD, associated with increased risk of glaucoma. This relation is not supported with enough data about characteristics pediatric patients with ASD in Indonesia. The aim of the study was to describe characteristics ASD in pediatric patient Cicendo Eye Hospital based on patients’ identity, clinical profile and obstetrics profile.Methods: This study used a descriptive method and conducted retrospectively. Data were collected from medical records of patient with ASD in Pediatric Ophthalmology and Strabismus Unit at Cicendo Eye Hospital, from January 2012 to December 2014. This study was conducted from July to November 2015. Total sampling based on inclusion criteria were used in this study. Statistic software was used to analyze data. Results: This study used a descriptive method and conducted retrospectively. Data were collected from medical records of patient with ASD in Pediatric Ophthalmology and Strabismus Unit at Cicendo Eye Hospital, from January 2012 to December 2014. This study was conducted from July to November 2015. Total sampling based on inclusion criteria were used in this study. Statistic software was used to analyze data. Conclusions: Characteristics pediatric patients with ASD at Cicendo Eye Hospital based on patients identity are mostly patients diagnosed in infant age group, from outside Bandung, and mostly boys. Based on clinical profile most diagnosis is congenital glaucoma, bilateral dominantly, and without complication. Based on obstetric profile most patients with ASD were born at term without difficulties. [AMJ.2016;3(4):616–70] DOI: 10.15850/amj.v3n4.948

Effect of Spondias dulcis Leaves Infusion on Glucose Transport Rate through Rat Intestine Epithelium Cell Membrane

Destia, Krisna, Martiana, Anna, Rachmayati, Sylvia

Althea Medical Journal Vol 3, No 4 (2016)
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Abstract

Background: Nowadays, people consume herbal remedies made from plants which are believed to be able to relieve certain symptoms and restore normal metabolic functions. Golden apple (Spondias dulcis) leaf has the potential to lower blood glucose. The purpose of this experiment was to observe the anti–hyperglycemic effect of S. dulcisleaves infusion on glucose transport rate through intestinal mucosal membrane of Wistar rats.Methods: An experimental study was conducted from October 2013 to November 2014. Nine male Wistar rats were selected aged 12–16 weeks, weighted 250–400 grams, healthy, actively moving, and had never been used in experiments. The rats were anesthetized, cut open and given three kinds of treatments: three kinds of glucose solutions were flowed through the intestinal tract using in situ perfusion method. Samples obtained from the rat’s intestine were measured with a spectrophotometer to obtain glucose rate transported through intestinal membrane from every treatment. The results of condition 1 and 2, and condition 1 and 3 were then compared.Results: The means of glucose transported through rat intestines epithelium cell membrane were 6.43 mg/dl, 9.40 mg/dl and 9.81 mg/dl. Statistic test result showed there was no significant difference on the glucose transported in every treatment.Conclusions: Glucose absorption rate in rat intestine doesnot decrease after they are given S. dulcis leaves infusion. Therefore, this experiment concludes that S. dulcis leaves do not affect the glucose transport rate in rat intestines epithelium cell membrane. [AMJ.2016;3(4):562–5] DOI: 10.15850/amj.v3n4.939

VO2 Max and Back and Leg Muscle Strength Profile of Universitas Padjadjaran Swimming Team

Pajar, Pitriyani Nurul, Farenia, Reni, Kuswiyanto, Rahmat Budi

Althea Medical Journal Vol 3, No 4 (2016)
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Abstract

Background: Cardiorespiratory endurance (VO2 max) and back and leg muscle strength are a few components required to support the performance of swimming athlete during competition. The objective of this study was to determine the VO2 max and back and leg muscle strength in high category level of Universitas Padjadjaran swimming team period 2014. Methods: A descriptive study was conducted to 19 swimmers of Universitas Padjadjaran in September 2014. The variables of this study were VO2 max and back and leg muscle strength. Then, the data were categorized based on the standard of The National Sports Committee of Indonesia.Results: The data obtained showed that the VO2 max of the majority of subjects was in the very good category (6/19 subjects) and the back muscle strength of the majority of subjects was in the very good category (10/19 subjects). In contrast, the leg muscle strength of majority of subjects was in the low category (11/19 subjects).Conclusions: The VO2 max and back muscle strength in high category level of the swimming team fulfilled the standard of The National Sports Committee of Indonesia. [AMJ.2016;3(4):499–502] DOI: 10.15850/amj.v3n4