JURNAL ILMU KEFARMASIAN INDONESIA
Vol 13 No 2 (2015): JIFI

Culture Broth Activity of Antibiotic Producer Bacteria (P301 Isolate) Against Staphylococcus aureus ATCC 25923 and Time Optimization of Secondary Metabolite Production


SULISTYANI, NANIK, NARWANTI, IIN



Article Info

Publish Date
23 Sep 2017

Abstract

Isolate P301 is an antibiotic producer bacteria isolated from rice plant ryzospher. This study was intended to identify the antibacterial activity of its culture broth againts Staphylococcus aureus ATCC 25923 and to identify the time optimization profileof secondary metabolite production from isolate P301 as producer antibiotics. Antibacterial activity was carried out using cup plate method by measuring the inhibitory zone around the wells. Optimization profile of production time of secondary metabolite was determined by plotting of the inhibition zone diameter versus incubation time. The result showed that isolate P301 culture broth inhibited the growth of S. aureus. According to the activity assay againts S. aureus, the optimum time for antibiotic production is after doing incubation for at least 11 days.


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Original Source : http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/82
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Journal Info

Abbrev

jifi

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Ilmu Kefarmasian Indonesia memuat tulisan ilmiah baik berupa naskah hasil penelitian maupun naskah konsep di bidang Kefarmasian. Diterbitkan setiap 2 (dua) kali dalam setahun yaitu pada bulan April dan ...