Jurnal Ilmiah Farmasi
Vol 5, No 1 (2008)

PROTECTIVE EFFECTS OF ETHYL ACETATE FRACTION OF Phaleria macrocarpa (Scheff) Boerl. ON OXIDATIVE STRESS ASSOCIATED WITH ALLOXAN-INDUCED DIABETIC RATS

Asih Triastuti (Unknown)
Jong Won Choi (Unknown)



Article Info

Publish Date
25 May 2009

Abstract

ABSTRACTOxidative stress resulting from the increased production of reactive oxygen species playsa key role in the development of diabetes mellitus and its complications. Phaleria macrocarpa, atraditional plant from Indonesia, has been used empirically to control cancer, arthritis, and diabetesin society. The anti-diabetic effect and antioxidant activity of ethyl acetate (EtOAc) of Phaleriamacrocarpa (PM) was investigated in alloxan-induced diabetic rats. After two weeks administrationof PM, liver antioxidant enzyme and hyperglycemic state were evaluated. The result showed thatEtOAc fraction treatments reduced blood glucose levels in diabetic rats by oral administration(P

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Journal Info

Abbrev

JIF

Publisher

Subject

Medicine & Pharmacology

Description

JIF merupakan jurnal yang dikelola oleh Prodi Farmasi Universitas Islam Indonesia, dan diterbitkan dua kali dalam setahun. Jurnal ini dirancang sebagai sarana publikasi penelitian yang mencakup secara rinci sejumlah topik dalam bidang farmasi yang berkaitan dengan farmasi sains dan teknologi serta ...