Black tiger shrimp Penaeus monodon post larvae were challenged with Vibrio harveyiÂ and butanol extract of selected marine sponge Aaptos aaptos to determine itsÂ antibacterial bioactive potential in vibriosis treatment. Based on the preliminaryÂ toxicity study, the A. aaptosÂ butanol extract with concentrations of 31.25, 62.5, andÂ 125 mg/L were selected in the study. Black tiger shrimp post larvae were challengedÂ with V. harveyi at 107 cfu/mL and immersed A. aaptosÂ butanol extract with theÂ concentration of 125 mg/L showed significantly in (P<0.05) decrease mortality of theÂ post larvae treated. Besides at this concentration, V. harveyi population in the rearingÂ water and the post larvae treated decreased compared to control (untreated postÂ larvae). Histological observation indicated that there was no changing on hepatopancreasÂ of the black tiger shrimp post larvae. Based on this result, it is suggestedÂ that the butanol extract of A. aaptos is a potential bioactive compounds source inÂ the treatment of vibriosis which may replaced the current antibiotics application.
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