HIV infection is associated with immune-compromised and rising in opportunistic infection (secondary infection). Therefore, theÂ number of mortality caused by HIV/AIDS is increasing. The use of ARV and development of HIV/AIDS management are expectedÂ to suppress the progress of HIV infection into AIDS and, therefore, the mortality can be diminished, while in fact most of the patientsÂ eventually suffer from AIDS due to secondary infection that commonly causes death. There should be a management by analysingÂ microorganisms that trigger secondary infection. The method of this study was observational descriptive with cross sectional design.Â HIV infected blood samples were using ELISA Antibody (IgG and IgM) and Polymerase Chain Reaction (PCR) on laboratory test. TheÂ result showed correlation between HIV/AIDS severity and the amount and types of secondary infection. The most common secondaryinfections were toxoplasm (96.77%), hepatitis C (22.58%), tuberculosis (19.35%), and hepatitis B (3.22%). Other less frequent secondaryÂ infections, which were quite difficult to diagnose and not commonly found in Indonesia, were West Nile Virus (25.81%), JapaneseÂ Encephalitis Virus (3.22%), and Enterovirus (3.22%). Due to MDGs (Millenium Development Goals) target and the results above,Â researchers are highly demanded to contribute in decreasing mortality related to AIDS through early detection of secondary infection,including type of infection which have not been commonly found in Indonesia, such as West Nile Virus and Nipah Virus. The discoveryÂ of secondary infection in this study was not enough to suppress the occurrence of infection in HIV/AIDS patients. Antimicrobes and goodÂ nutrition are required. Moreover, there should be either a primary or secondary prophylaxis to prevent secondary infection that raisesÂ the number of mortality and morbidity of HIV/AIDS patients. The result of this study was to meet the target of MDGs by establishingÂ new policies in handling HIV/AIDS infections and have potential as model for policy control in HIV/AIDS.
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