Indonesian Journal of Tropical and Infectious Disease
Vol 4, No 4 (2013)

ANALYSIS ON WHOLE BLOOD, SGOT, SGPT, AND TNF-a EXAMINATION IN PATIENTS WITH NON-DENGUE AND POSITIVE DENGUE FEVER (DF/DHF)

Anggraini, Rahayu ( Institute of Tropical Disease, Universitas Airlangga )
Nasronudin, Nasronudin ( Institute of Tropical Disease, Universitas Airlangga )



Article Info

Publish Date
06 Jul 2015

Abstract

Background: In Indonesia has four serotypes, the DEN-1, DEN-2, DEN-3 and DEN-4. The management of Dengue virus becomes difficult because the patients were infected with different clinical profiles depending on the serotypes and genotypes of infecting dengue virus. Consequently, the diagnosis and treatment becomes difficult. Aim: The purpose of this study was to identify the difference between the results of laboratory tests between non-dengue fever and positive dengue fever. Method: This study was an observational cross-sectional study. Fifteen samples were diagnosed with dengue fever and fifteen samples with negative dengue fever on NS1, IgM / IgG-anti-DHF strip test results. Laboratory tests comprising whole blood, SGOT, SGPT, and TNFa were first examined when the patient came to the hospital. The collected data were analyzed by Chi-Square test SPSS version 13 for Windows. Result: The results of the study in two groups regarding sex, age, days of fever, grade, hemoglobin levels, leukocytes count, platelet count, hematocrit percentage, SGOT levels, and TNFa level were not significantly different with p > 0.050, whereas the SGPT level in non-dengue increased 3 x of normal value of 66.7%, n = 10/15 and in positive dengue fever the SGPT level was within normal limits, found in 60%, n = 9/15, so there was significant difference with p = 0.022 (p < 0.05). Conclusion: in non-dengue SGOT and SGPT levels increased of 1–3 times the normal value. In positive dengue fever SGOT levels increased 1–3 x normal value, but SGPT levels was within normal value, so SGPT levels can be used as a predictive factor for distinguishing the two types of fever.

Copyrights © 2013






Journal Info

Abbrev

IJTID

Publisher

Subject

Earth & Planetary Sciences Health Professions Medicine & Pharmacology Public Health

Description

This journal is a peer-reviewed journal established to promote the recognition of emerging and reemerging diseases specifically in Indonesia, South East Asia, other tropical countries and around the world, and to improve the understanding of factors involved in disease emergence, prevention, and ...