STIFAR - Sekolah Tinggi Ilmu Farmasi
MFI Vol 7 No 2

AKTIFITAS HIPOKOLESTEROL AIR REBUSAN JAMUR KUPING HITAM (Auricularia polytricha (Month.) Sacc.) PADA TIKUS YANG DIBERI DIET LEMAK TINGGI

Puspitaningrum, Ika ( Ika Puspitaningrum, Lia Kusmita )
Kusmita, Lia ( Ika Puspitaningrum, Lia Kusmita )



Article Info

Publish Date
22 Jul 2014

Abstract

The aim of this research was to know the effects and dosage of Jamur Kuping Hitam (Auricularia polytricha (Month.) Sacc. ) water extract as hipocholesterol. The research was done with post test only randomized control group design. Animal trials Wistar male rats as much as 25 divided by 5 groups. Group I (negative control) were given aquadest, II (positive control) were given Simvastatin 1,26 mg/kg, groups III, IV and V were given Jamur Kuping Hitam water extract 6,3; 12,6 and 25,2 ml/kg. All groups were given a high fat diet (DLT) which is mixtures standard feed and oil pigs (90:10) for 7 days. All treatment was done by oral. Measurement of total cholesterol concentration done on days 7 and 14 after treatment. Therefore, total cholesterol concentration was analyzed statistically with the Kruskal-Wallis and Mann-Whitney using SPSS release 16. The results obtained Jamur Kuping Hitam (Auricularia polytricha (Month.) Sacc.) water extract have effect hipocholesterol with dosage is 25,2 ml/kg. Key words: water extract, jamur kuping hitam, hipocholesterol, total cholesterol

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