Kusumo, Fajar Adi
Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

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Link of Nasopharyngeal Carcinoma and Epstein-Barr Virus Sugiyanto, Sugiyanto; Aryati, Lina; Kusumo, Fajar Adi; Hardianti, Mardiah Suci
Biology, Medicine, & Natural Product Chemistry Vol 7, No 2 (2018)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (468.443 KB) | DOI: 10.14421/biomedich.2018.72.51-55

Abstract

Nasopharyngeal Carcinoma (NPC) is a cancer that occurs in nasopharynx which is associated with Epstein-Barr Virus (EBV). Mutation agents in nasopharyngeal neoplasms occur because of EBV infection. Transformation of B-cells due to EBV causes hormone imbalance in lymphoid cells or nasopharyngeal epithelial tissue. Rates of EBV infection have been shown to be prognostic to NPC. The basic level of EBV DNA can be used for stratification prognosis, with higher titers showing greater disease severity and worse outcomes. With mathematical models, there is a correlation between the increase in Epstein-Barr Virus and the increase in Invasive Carcinoma Cells or increase in Nasopharyngeal Carcinoma Cells.
A Stability Mathematical Model of Nasopharyngeal Carcinoma on Cellular Level Sugiyanto, Sugiyanto; Kusumo, Fajar Adi; Aryati, Lina; Hardianti, Mardiah Suci
Biology, Medicine, & Natural Product Chemistry Vol 5, No 2 (2016)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (452.355 KB) | DOI: 10.14421/biomedich.2016.52.61-64

Abstract

This paper discussed the stability of “Tumorigenesis Models” to link between EBV and carcinoma of the nasopharyngeal from normal cell to invasive carcinoma. The review on this case accomplished the previous theorem of equilibrium point on “Tumorigenesis Models”.