Haerani Rasyid, Haerani
Unknown Affiliation

Published : 3 Documents
Articles

Found 3 Documents
Search

Anthropometry-based Body Fat Percentage Predicts High hs-CRP in Chronic Kidney Disease Patients Thaha, Mochammad; Empitu, Maulana Antiyan; Kadariswantiningsih, Ika Nindya; Nugroho, Cahyo Wibisono; Hasanatuludhhiyah, Nurina; Rasyid, Haerani; Hakim, Zaky El; Suryansyah, Maulana Muhtadin; Alda, Rieza Rizqi; Alsagaff, Mohammad Yusuf; Amin, Mochammad; Santoso, Djoko; Suzuki, Yusuke
The Indonesian Biomedical Journal Vol 10, No 2 (2018)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v10i2.397

Abstract

BACKGROUND: Obesity is an important cardiovascular risk factor and associated with low grade inflammation in chronic kidney disease (CKD) patients. This study aims to assess the association between body fat with serum high sensitivity C-reactive protein (hs-CRP) level in CKD patients.METHODS: A cross-sectional study was performed in 71 CKD patients. Anthropometric measurements included body weight, height, body mass index (BMI), body fat percentage (BFP), skinfold thickness (SKF) of triceps and biceps were performed by trained physician. BFP was calculated using Kwok’s Formula and hs-CRP was measured by Particle enhanced Turbidimetry.RESULTS: The averaged BMI of our subjects was 25.8±4.4. There was no significant difference in BMI between pre-dialysis and hemodialysis CKD patients. Positive correlation was found between BFP and hs-CRP (r=0.266; p<0.05), while there was no significant correlation between BMI and hs-CRP.CONCLUSION: Body fat percentage was associated with hs-CRP. Hence, it will be more beneficial to assess nutritional status in CKD using BFP rather than BMI alone since it was demonstrated to correlate with hs-CRP in our studyKEYWORDS: CKD, obesity, inflammation, body fat, hs-CRP
Could Complete Blood Count Parameters and Non-fasting Cholesterol Profile Describe Inflammation and Oxidative Stress in Chronic Kidney Disease? Kadariswantiningsih, Ika Nindya; Thaha, Mochammad; Nugroho, Cahyo Wibisono; Hamidah, Berliana; Rasyid, Haerani; Hakim, Zaky El; Suryansyah, Maulana Muhtadin; Alsagaff, Mohammad Yusuf; Santoso, Djoko; Empitu, Maulana Antiyan; Suzuki, Yusuke
The Indonesian Biomedical Journal Vol 10, No 3 (2018)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v10i3.451

Abstract

BACKGROUND: Establishment of inexpensive clinical laboratory tests to evaluate inflammation and oxidative stress is urgently needed in the limited resources settings. This study aims to investigate the potential of complete blood count (CBC) parameters and non-fasting cholesterol profile parameters to describe inflammation and oxidative stress in chronic kidney disease (CKD) patients.METHODS: Measurement of CBC, non-fasting cholesterol profile, high sensitivity C-reactive protein (hs-CRP) and malondialdehyde (MDA) were performed in 71 CKD patients grouped into hemodialysis (HD) and non-hemodialysis (non-HD). Correlation analysis were performed to assess the potential of CBC and cholesterol profile to describe the level of hs-CRP and MDA.RESULTS: In the HD group, total cholesterol was moderately associated with hs-CRP while total cholesterol/HDL-C ratio, monocyte/HDL-C ratio, monocyte/LDL-C ratio, neutrophil/HDL-C ratio, neutrophil/LDL-C ratio, platelet/HDL-C ratio and platelet/LDL-C ratio were strongly associated with hs-CRP. In the non-HD group,only neutrophil/total cholesterol ratio and platelet/total cholesterol ratio that were associated with hs-CRP. Total cholesterol, monocyte/LDL-C ratio, neutrophil/LDL-C ratio and platelet/LDL-C ratio were moderately associated with MDA while total cholesterol/HDL-C ratio, monocyte/HDL-C ratio, neutrophil/HDL-C ratio and platelet/HDL-C ratio were strongly associated respectively with MDA in HD group. In the non-HD group, total cholesterol/HDL-C ratio, neutrophil/HDL-C ratio and platelet/HDL-C ratio were moderately associated with MDA in non-HD group while monocyte/HDL-C ratio was weakly associated with MDA.CONCLUSION: Some CBC parameters and non-fasting cholesterol profile such as cholesterol/HDL-C, monocyte/HDL-C, neutrophil/HDL-C and platelet/HDL-C ratio showed a potential to describe the inflammation and stress oxidative markers, given some strong associations with the level of hs-CRP and MDA. Further study is needed to assess whether this parameter represent long-term prognostic value among CKD patients.KEYWORDS: inflammation, oxidative stress, CRP, MDA, TAC, 8-OHdG, CBC, cholesterol
Conn’s Syndrome Akibat Adenoma Adrenal Rasyid, Haerani; Bakri, Syakib; Kasim, Hasyim; Hidayat, Andi Rahmat; Syarif, Syarif; Azis, Abd
Jurnal Penyakit Dalam Indonesia Vol 6, No 2 (2019)
Publisher : Internal Medicine Department, Faculty of Medicine Universitas Indonesia-RSCM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (445.018 KB) | DOI: 10.7454/jpdi.v6i2.205

Abstract

Conn’s syndrome merupakan sindrom yang ditandai dengan peningkatan kadar aldosteron yang menyebabkan retensi natrium dan peningkatan ekskresi kalium melalui urin. Sindrom ini ditandai dengan trias hipokalemia, hipertensi, dan alkalosis metabolik. Artikel ini membahas mengenai laporan kasus pasien hipertensi tidak terkontrol dengan gejala neuromuskular yang diakibatkan oleh hipokalemia berulang. Setelah dilakukan evaluasi tes pencitraan, ditemukan gambaran tumor adrenal kiri dan kemudian dilakukan tindakan adrenalektomi unilateral. Hasil pemeriksaan histopatologi tumor didapatkan gambaran yang sesuai dengan adenoma adrenal. Setelah tindakan adrenalektomi unilateral, pasien menunjukkan perbaikan klinis dan laboratorium. Kata kunci : Conn’s syndrome, Hipertensi, HipokalemiaConn’s Syndrome Due to Adrenal AdenomaConn's syndrome is characterized by an increase in aldosterone level causes sodium retention and an increase in urine excretion of potassium. This syndrome is characterized by trias hypokalemia, hypertension, and metabolic alkalosis. This article discussed a case report of a patient with uncontrolled hypertension with neuromuscular symptoms caused by recurrent hypokalemia. After an evaluation of the imaging test, we found a left adrenal tumor then we performed unilateral adrenalectomy surgery. Histopathology examination from the excised tumor revealed the adrenal adenoma. After unilateral adrenalectomy, the patient showed clinical and laboratory improvement.