Dimas Priantono, Dimas
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Tantangan dalam Tata Laksana Malaria Berat di Rumah Sakit Daerah Terpencil di Indonesia

Jurnal Penyakit Dalam Indonesia Vol 4, No 1 (2017)
Publisher : Jurnal Penyakit Dalam Indonesia

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Abstract

Malaria falciparum merupakan infeksi yang disebabkan oleh Plasmodium falciparum (Pf) yang sering menimbulkan komplikasi hingga timbul malaria berat dengan mortalitas yang tinggi. Manajemen malaria di daerah terpencil memiliki tantangan tersendiri sebagai akibat dari kurangnya kemampuan sumber daya manusia dan fasilitas diagnosis dan tata laksana yang memadai. Pada artikel ini akan dibahas mengenai kasus infeksi Malaria Falciparum dengan diagnosis yang ditegakkan secara pasti melalui pemeriksaan mikroskopis darah yang menyatakan adanya parasit Pf. Pasien sudah menerima Artemisinin-Based Combination Therapy (ACT) berupa dihidroartemisinin (DHA)-piperakuin (PPQ) dan primakuin (PQ). Pada evaluasi setelah pemberian obat ACT dan primakuin, tidak ada perbaikan klinis dan mikroskopis. Pengobatan malaria lini kedua berupa kina, doksisiklin dan PQ diberikan dan memberikan perbaikan klinis dan mikroskopis.Kata Kunci: Artemisinin Combination Therapy, doksisiklin, kina, malaria falsiparum  Challenges in Providing Treatment of Severe Malaria Case in a District Hospital of Remote Area in IndonesiaSevere Malaria is commonly found due to Plasmodium falciparum infection, which is causing high mortality in patient. A Severe case might be difficult to treat optimally in the remote settings area that could be due to lack in awareness of disease manifestation and inadequate diagnostic facilities. We report a case of Severe Malaria Falciparum infection, confirmed by blood smear eamination of Plasmodium falciparum (Pf) parasites. Patient had received Artemicinin Based Combination Therapy (ACT), which consisted of dihydroartemisinin (DHA)-piperaquine and primaquine (PQ) with no clear clinical and microscopy improvement. The second line anti malaria consisted of quinine, doxycycline, and PQ was then initiated, showing clinical and microscopy responses.

Tantangan dalam Tata Laksana Malaria Berat di Rumah Sakit Daerah Terpencil di Indonesia

Jurnal Penyakit Dalam Indonesia Vol 4, No 1 (2017)
Publisher : Internal Medicine Department, Faculty of Medicine Universitas Indonesia-RSCM

Show Abstract | Original Source | Check in Google Scholar | Full PDF (1722.547 KB)

Abstract

Malaria falciparum merupakan infeksi yang disebabkan oleh Plasmodium falciparum (Pf) yang sering menimbulkan komplikasi hingga timbul malaria berat dengan mortalitas yang tinggi. Manajemen malaria di daerah terpencil memiliki tantangan tersendiri sebagai akibat dari kurangnya kemampuan sumber daya manusia dan fasilitas diagnosis dan tata laksana yang memadai. Pada artikel ini akan dibahas mengenai kasus infeksi Malaria Falciparum dengan diagnosis yang ditegakkan secara pasti melalui pemeriksaan mikroskopis darah yang menyatakan adanya parasit Pf. Pasien sudah menerima Artemisinin-Based Combination Therapy (ACT) berupa dihidroartemisinin (DHA)-piperakuin (PPQ) dan primakuin (PQ). Pada evaluasi setelah pemberian obat ACT dan primakuin, tidak ada perbaikan klinis dan mikroskopis. Pengobatan malaria lini kedua berupa kina, doksisiklin dan PQ diberikan dan memberikan perbaikan klinis dan mikroskopis.Kata Kunci: Artemisinin Combination Therapy, doksisiklin, kina, malaria falsiparum  Challenges in Providing Treatment of Severe Malaria Case in a District Hospital of Remote Area in IndonesiaSevere Malaria is commonly found due to Plasmodium falciparum infection, which is causing high mortality in patient. A Severe case might be difficult to treat optimally in the remote settings area that could be due to lack in awareness of disease manifestation and inadequate diagnostic facilities. We report a case of Severe Malaria Falciparum infection, confirmed by blood smear eamination of Plasmodium falciparum (Pf) parasites. Patient had received Artemicinin Based Combination Therapy (ACT), which consisted of dihydroartemisinin (DHA)-piperaquine and primaquine (PQ) with no clear clinical and microscopy improvement. The second line anti malaria consisted of quinine, doxycycline, and PQ was then initiated, showing clinical and microscopy responses.

An Indonesian Pregnant Woman with Lung Cancer and Liver Metastasis : A Case Report

Indonesian Journal of Cancer Vol 12, No 2 (2018): April-June
Publisher : National Cancer Center - Dharmais Cancer Hospital

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Abstract

Background: Lung cancer in pregnancy is a rare disease compared to other types of cancer. However, special issue should be applied in order to maximize benefit for mother without harming the fetus.Methods: We present a case of 37-year-old, five months pregnant woman who came to the hospital with chief complain of shortness of breath. Later on, she was found to have a stage IV Non-Small Cell Lung Cancer (NSCLC) with adenocarcinoma subtype.Result: This may be the first lung cancer in pregnancy reported in Indonesia. Being a developing country, several challenges emerged before diagnosing patient of having lung cancer.Conclusion: Careful considerations along with multidisciplinary approach are necessary to provide the best care for the patient.