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Management of Lowe syndrome: a case report Prasetyo, Risky Vitria; Setiawan, Heru; Soemyarso, Ninik Asmaningsih; Noer, Mohammad Sjaifullah; Irwanto, Irwanto; Gunawan, Prastiya Indra; Loebis, Rozalina; Utomo, Sri Andreani; Tirthaningsih, Ni Wayan
Paediatrica Indonesiana Vol 55 No 3 (2015): May 2015
Publisher : Indonesian Pediatric Society

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Abstract

Lowe syndrome (the oculocerebrorenal syndrome of Lowe, OCRL) is a multisystem disorder characterized by anomalies affecting the eyes, nervous system and kidneys.1-3 The disorder was first recognized by Lowe et al. in 1952, and described as a unique syndrome with organic aciduria, decreased renal ammonia production, hydrophthalmos, and mental retardation. In 1954, renal Fanconi syndrome was recognized as being associated with Lowe syndrome and in 1965, a recessive X-linked pattern of inheritance was determined.2,4 Lowe syndrome is a very rare disease, with an estimated prevalence in the general population of 1 in 500,000. According to the Lowe Syndrome Association (LSA) in the USA, the estimated prevalence is between 1 and 10 affected males in 1,000,000 people, with 190 living in the year 2000. The Italian Association of Lowe Syndrome estimated that there were 34 Lowe syndrome patients (33 boys and one girl) living in Italy in the year 2005.2,4,5 It almost exclusively affects males.6 Physicians may not be familiar with Lowe syndrome due to its rarity.4
Pengaruh Penggunaan Gadget terhadap Penurunan Kualitas Penglihatan Siswa Sekolah Dasar Puspa, Andriana Kirana; Loebis, Rozalina; Nuswantoro, Djohar
Global Medical & Health Communication (GMHC) Vol 6, No 1 (2018)
Publisher : Faculty of Medicine Universitas Islam Bandung

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Abstract

Layar gadget yang menggunakan tulisan kecil akan memunculkan gejala computer vision syndrome. Lebih dari 90% pengguna komputer dalam waktu lama mengalami mata lelah, penglihatan buram, penglihatan ganda, pusing, dan mata kering. Penelitian ini bertujuan mengetahui kualitas penglihatan siswa-siswi Sekolah Dasar yang menggunakan gadget dalam jangka waktu yang lama. Penelitian analitik observasional cross-sectional dengan 43 subjek di SD Muhammadiyah 4 Surabaya pada Maret–November 2015 dengan mengambil data primer, yaitu kuesioner serta pemeriksaan mata Snellen chart dan tear break-up time test. Hasil kuesioner diolah untuk mengetahui tingkat paparan. Hasil pemeriksaan mata dan tingkat paparan dihitung dengan rasio prevalensi dan uji hipotesis chi-kuadrat dengan tingkat kepercayaan 95%. Hasil kuesioner didapatkan kategori paparan ringan 56%, sedang 23%, dan berat 21%. Pemeriksaan Snellen chart diperoleh hasil tajam penglihatan menurun pada 47% dan normal pada 54%. Hasil tear break-up time test diperoleh mata kering sebanyak 88% dan tidak mengalami sebanyak 12%. Simpulan, seluruh tingkat kategori paparan mempunyai risiko kecil untuk mengalami penurunan atau gangguan tajam penglihatan, tetapi mempunyai risiko yang sama besar untuk mengalami mata kering. THE USING OF GADGET AND ITS EFFECT OF DECREASING THE QUALITY OF ELEMENTARY SCHOLLS STUDENTSThe small fonts in a gadget’s screen evokes the symptoms of computer vision syndrome. More than 90% computer users may experience eyestrain, blurred vision, diplopia, dizziness and dry eyes after prolonged use. The purpose of this study was to ascertain the vision quality in elementary students that has been using gadgets for long period. An observational analytic cross-sectional study in 43 subjects of SD Muhammadiyah 4 Surabaya on March until November 2015 by taking primary data, specifically questionnaire and eye examination Snellen chart and tear break-up time test. The questionnaire’s result will be calculated to acknowledge the level of exposure. The result of the eye examination and level of exposure will be calculated with prevalence ratio and chi-square hypothesis test by 95% confidence interval. The result from the questionnaire was 56% of subjects were light exposure category, 23%  were moderate and 21% were severe. The examination with Snellen chart results in the decreasing of visual acuity in 47% subjects and normal in 54% subjects. The results of tear break-up time test was the incidence of dry eyes was 88% and no experience of dry eyes was 12%. In conclusion, all categories of exposure have a small risk of decreased or disorder of visual acuity, but have the similar high-level of risk in experiencing dry eyes.
The Correlation between Family Socioeconomic Status and the Delayed Treatment of Retinoblastoma Patients at Dr. Soetomo General Hospital Surabaya Naimatuningsih, Nanning; Soebagjo, Hendrian; Setiawati, Rosy; Loebis, Rozalina
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol 10, No 2 (2019): VOL X, NO. 2 (2019) : Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

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Abstract

Introduction: Retinoblastoma is a cancer with the highest incidence in children and the second type of cancer that most often causes death in children in Indonesia. The level of delay in attending treatment for retinoblastoma patients in Dr. Soetomo General Hospital Surabaya is still high because in general the patients come with an advanced stage, they are already in serious condition or with a poor prognosis. Treatment delay from the patients can be caused by the patients that are not feeling disturbed by the disease, not aware of the dangers of the disease, feel afraid, have no cost, the family does not allow them to see the doctor, and the health facilities are unaccessable. One of the factors that influence decision making whether or not someone comes to seek treatment is their socioeconomic status. A high education level will make it easier for a person or society to obtain and understand information to solve health problems that are happening in their families, and then with a high level of occupation and income, people are able to choose health services for themselves. The aim of this research is to analyze the correlation between family socioeconomic status with the delayed treatment for retinoblastoma patients at Dr. Soetomo General Hospital Surabaya.Methods: This research used observational analytic cross-sectional study. This research was conducted with the help of 33 retinoblastoma patients and families of retinoblastoma patients in the Outpatient Unit of the Poli Onkologi Satu Atap (POSA) Mata at Dr. Soetomo General Hospital Surabaya, and was taken by total sampling.Results: The results were obtained from 33 samples, 18.2% of patients came with a good prognosis, and 81.8% of patients came with a poor prognosis. The Fisher’s Exact Test analysis (α = 0.05) was used to determine the correlation between the father’s educational level and the delayed treatment of retinoblastoma patients (p = 0.322), correlation between the mother’s educational level and the delayed treatment of retinoblastoma patients (p = 0.129), correlation between the father’s level of occupation and the delayed treatment of retinoblastoma patients (p = 0.028), correlation between the mother’s occupational level and the delayed treatment of retinoblastoma patients (p = 0.640), correlation between the family income level and the delayed treatment of retinoblastoma patients (p = 0.026).Conclusion: There were significant correlation between father’s occupational level and family income level with the delayed treatment of retinoblastoma patients. Meanwhile there were no significant correlation between father’s educational level, mother’s educational level, and mother’s occupational level with the delayed treatment of retinoblastoma patients.