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EFEK ROSELLA MERAH KERING TERHADAP KADAR MDA SERUM TIKUS STRAIN WISTAR YANG DI PAPAR ASAP ROKOK Herdiani, Novera; Afridah, Wiwik
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 2 (2017): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i2.606

Abstract

Abstract: Cigarette smoke contains free radicals. Currently the number of smokers in Indonesia arestill high. This study aims to analyze the effects of red rosella of dried on the prevention of theincrease of Malondialdehyde (MDA) serum of strain wistar rats exposed to cigarette smoke. Thetotal sample of 24 male rats and divided into four groups: negative control, positive control, treatment of red rosella on dried dose 540 mg/bw, and red rosella on dried dose 810 mg/bw. Negativecontrol only given with standard feed. Positive control given by standard feed and exposed to 2cigarettes a day. Treatment group were feed by standard and red rosella of dried in the morning andexposed to 2 cigarettes after that. This study was conducted for 21 days. At the end of the study,blood serum was analyzed to determine MDA. The results of the study of MDA serum test isanalyzed with One Way ANOVA and followed by Tukey LSD test at 5% level. The giving of redrosella on dried dose 540 mg/bw and red rosella on dried dose 810 mg/bw can significantly preventthe increase of MDA serum in strain wistar rats exposed to cigarette smoke.
GAMBARAN HISTOPATOLOGI PARU TIKUS WISTAR SETELAH DIBERI PAPARAN ASAP ROKOK Herdiani, Novera; Putri, Endah Budi Permana
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 2 (2018): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i2.583

Abstract

Abstract: Cigarette smoke is the main cause of lung obstruction. One of the obstructions in real that iscaused by cigarette smoke is oxidative stress. Oxidative stress trigger inflammation response occur andlung obstruction. Cigarette smoke able to cause lung histopathology changes like lungs obstruction onalveolus wall. Red dragon fruit extract tackle free radical then able to against the oxidative stress. Theobjective of this study to examines the image of rat lung histopathology under exposed cigarette smoke.Twenty four Wistar rats divided four groups: negative control, positive control, red dragon fruit extracttreatment of 7,2 g/200 g WB, and red dragon fruit extract10,8 g/200 g WB. Negative control only givenstandard feed. Positive control given standar feed and exposed 21 cigarette per day. Treatment groupgiven feed during 21 days. In the 22nd day rats be sacrificed, the lung taken out for observation andimage of rat lung histopathology changes by making lung organ histopathology preparationhematoxicillin Eosion (HE) staining and observed under magnification light microscope 400x. The endresult of the study indicate the finding of changes in lung histopathology such as obstruction level overthe lung tissue higher, alveolar macrophage covered alveoli after being exposed cigarette smoke. Groupwhich does not exposed cigarette smoke, lung alveolus macrophage in normal condition, there are noobstruction or alveolus macrophage occurred, its alveolar macrophage does no covering alveoli.Treatment group administered fruit dragon extract dose 10,8 g/200 g WB and dose 7,2 g/200 g WB seemalmost the same with negative control treatment. Conclusion of the research is cigarette smoke exposecan influence the number of alveolar macrophage on wistar rats. Suggestion very required furtherresearch on oxdative stress parameter.
PEMILIHAN TEKNIK SAMPLING BERDASARKAN PERHITUNGAN EFISIENSI RELATIF Arieska, Permadina Kanah; Herdiani, Novera
Jurnal Statistika Universitas Muhammadiyah Semarang Vol 6, No 2 (2018): Jurnal Statistika
Publisher : Program Studi Statistika, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Muham

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Abstract

Metode sampling yang dapat digunakan untuk pengambilan sampel antara lain Simple Random sampling dan Stratified Sampling. Pada Simple Random Sampling, setiap elemen populasi memiliki kesempatan yang sama untuk diambil. Sedangkan Stratified Sampling adalah teknik pengambilan sampel dengan membuat strata (tingkatan/kelas) didalampopulasi. Kedua metode sampling ini akan dibandingkan untuk memperoleh Margin of Error (MoE) yang lebih kecil pada data Indeks Massa Tubuh (IMT)  Mahasiswa Fakultas Kesehatan Universitas Nahdlatul Ulama Surabaya. Didapatkan bahwa nilai varian penduga parameter pada Stratified Sampling lebih kecil dibandingkan dengan Simple Random Sampling. Penghitungan efisiensi relatif menunjukkan bahwa nilai varianpenduga parameter pada teknik Simple Random Sampling 1,3 kali lebih besar dibandingkan dengan Stratified Sampling. Secara deskriptif, dapat disimpulkan bahwa stratified sampling lebih efisien digunakan untuk data IMT Mahasiswa dibandingkan teknik Simple Random Sampling.  Kata kunci : Simple Random sampling,  Stratified Sampling, Efisiensi Relatif
ADMINISTRATION OF RED ROSELLA’S PETALS EXTRACT (Hibiscus sabdariffa) INCREASE LEVEL OF SUPEROXIDE DISMUTASE (SOD) WISTAR RATS WHICH INDUCED BY REPETEADLY HEATED COOKING OIL Herdiani, Novera; Wirjatmadi, Bambang; Adriani, Merryana
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Background:  repeatedly heated cooking oil is cooking oil that is used many times, had saturated fatty acids containing free radicals. Red rosella petals extract contains antioxidants to minimize the effects of repeatedly heated cooking oil that can raise the levels of SOD. The aim of this study was to analyzed the effect of red rosella’s petals extract against oxidative stress of Wistar rats were induced by repeatedly heated cooking oil with examine levels of  serum SOD.This research was conducted True Experimental Laboratory with a completely randomized design (CRD) and use the post test. The sample consisted of 24 male rats were divided 4 groups: negative control (fed with standard diet); positive control (fed with standard diet + administered by repeatedly heated cooking oil as much as 2.1 ml / kg bw); treatment group dose I (fed with standard diet + administered by red rosella extract dose 540 mg / kg bw + repeatedly heated cooking oil as much as 2.1 ml / kg bw), and treatment group dose II (fed with standard diet + administered by red rosella extract dose 810 mg / kg bw + repeatedly heated cooking oil as much as 2.1 ml / kg bw). Analysis of data using statistical test One Way ANOVA and Tukey HSD (α = 0.05).Results: There were significant differences (p = 0.000) between groups. Red rosella extract treatment group dose 810 mg / kg bw and 540 mg / kg bw were significantly different from the positive control (p = 0.000). Red rosella extract group dose 540 mg / kg bw was significantly different from the negative control (p = 0.000). Red rosella extract group dosage of 810 mg / kg bw was not differ significantly from the control group (p = 0.171).Conclusion: The red rosella’s petals extract dose of 810 mg / kg bw and dose of 540 mg / kg bw were able to prevent oxidative stress. Optimal deose of red rosella petals extract dose of 810 mg / kg bw was the most effective, because the higher antioxidant activity (67.33%) at dose 810 mg / kg bw dose than 540 mg / kg bw.
EFEK ANTIOKSIDAN EKTRAK BUAH NAGA MERAH (Hylocereus polyrhizus) TERHADAP MAKROFAG ALVEOLAR TIKUS YANG DIPAPAR ASAP ROKOK Herdiani, Novera; Putri, Endah Budi Permana
Conference on Innovation and Application of Science and Technology (CIASTECH) CIASTECH 2018 "Inovasi IPTEKS untuk mendukung Pembangunan Berkelanjutan"
Publisher : Universitas Widyagama Malang

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Abstract

Asap rokok mengandung radikal bebas yang membahayakan tubuh. Apabila radikal bebas terlalu banyak maka antioksidan tidak mampu mengatasinya. Buah naga merah merupakan sumber antioksidan. Penelitian ini bertujuan untuk menganalisa aktivitas antioksidan ekstrak buah naga merah dan makrofag alveolar tikus dipapar asap rokok. Total sampel 24 tikus jantan dan dibagi 4 kelompok: kontrol negatif, positif, perlakuan ekstrak buah naga merah dosis 7,2 g/200 g BB, dan 10,8 g/200 g BB. Kontrol negatif hanya diberi pakan standar. Kontrol positif diberi pakan standar dan dipapar 2 rokok/hari. Kelompok perlakuan diberi pakan standar dan ekstrak buah naga merah di pagi hari dan setelah itu dipapar 2 rokok. Penelitian dilakukan selama 21 hari. Antioksidan ekstrak buah naga merah diuji dengan metode DPPH dan paru tikus diamati dengan pewarnaan Hematoksilin Eosin (HE) untuk menentukan makrofag alveolar. Makrofag alveolar dianalisis One Way ANOVA dan uji HSD. Hasil penelitian menunjukkan ekstrak mengandung 16181 ppm antioksidan. Makrofag alveolar kontrol positif berbeda nyata dengan semua perlakuan lainnya. Pemberian ekstrak dapat menangkal radikal bebas dan mencegah peningkatan jumlah makrofag alveolar pada tikus dipapar asap rokok.
GAMBARAN POLA MAKAN DAN AKTIVITAS FISIK PENDERITADIABETES MELLITUS DI RW 01 KELURAHAN JAGIR SURABAYA Herdiani, Novera
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 2 No 2 (2018): Medical Technology and Public Health Journal September 2018
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v2i2.568

Abstract

Diabetes Mellitus (DM) is a group of hitrogen disorder characterized by the increased of bloodglucose level or hyperglycemia. It was reported from WHO that population study of Diabetes Mellitusin various countries, the number of Diabetes Mellitus patients in 2000 in Indonesia got the biggest4th rank of the Diabetes Mellitus patients number with prevalence of 8.4 million inhabitants. HandlingDiabetes Mellitus sufferers is a lifelong responsibility. Therefore, handling Diabetes Mellitus needsinitiative and regularity so all sufferers should understand how to run diet and exercise to control thedisease. The purpose of this study is to find out the description of eating and physical activity patternsof Diabetes Mellitus sufferers in RW 01, Kelurahan Jagir Surabaya. The design of the study used wascross-sectional, the sample was 56 people which selection was carried out by sampling techniqueused a Consecutive Sampling. The variable in this study was eating and physical activity patterns ofDiabetes Mellitus patients. The data were collected through questionnaires, then the statistical datawere processed descriptively by using common and frequency distribution tables used scoring datacollection procedures. The result of the study of Eating pattern of Diabetes Mellitus sufferers, 54%of the patients had lack of the calories needs in a day, based on the fulfillment of the diet schedule,more than half diabetics (70%) did not conduct an eating schedule and based on the consumption ofsweet foods (68%) diabetics consumed food sweet. The result of physical activity of the diabeticswhose age was <30 years was varied 33.33% with the result of less physical activity and optimalphysical activity as 4 people (57.14%) were college educated. The result which was varied that 50%had high school education with less physical activity, while the patients whose education waselementary and junior high had physical activity minimally. Based on the result, it is concluded thatall Diabetes Mellitus sufferers (100%) have not met a good eating pattern, physical activity patternsof Diabetes Mellitus patients (30%) have` less physical activity.
GAMBARAN POLA MAKAN DAN AKTIVITAS FISIK PENDERITA DIABETES MELLITUS DI RW 01 KELURAHAN JAGIR SURABAYA Herdiani, Novera
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 1 No 2 (2017): Medical Technology and Public Health Journal September 2017
Publisher : UNUSA Press

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Abstract

Diabetes Mellitus (DM) is a group of hitrogen disorder characterized by the increased of blood glucose level or hyperglycemia. The number of Diabetes Mellitus patients in 2000 in Indonesia got the biggest 4 rank with prevalence of 8.4 million inhabitants. Therefore, handling Diabetes Mellitus needs diet and exercise to control the disease. The purpose of this study is to find out the description of eating and physical activity patterns of Diabetes Mellitus sufferers in RW 01, Kelurahan JagirSurabaya. The design of the study used was cross-sectional, the sample was 56 people. The variable in this study was eating and physical activity patterns of Diabetes Mellitus patients. The data were collected through questionnaires, then the statistical data were processed descriptively by using common. The result of the study of Eating pattern of Diabetes Mellitus sufferers, 54% of the patients had lack of the calories needs in a day, based on the fulfillment of the diet schedule 70% did notconduct an eating schedule and based on the consumption of sweet foods 68%. The result of physical activity of the diabetics whose age was <30 years was varied 33.33% with the result of less physical activity and optimal physical activity as 4 people (57.14%). The result which was varied that 50% had high school education with less physical activity. Based on the result, it is concluded that all Diabetes Mellitus sufferers (100%) have not met a good eating pattern, physical activity patterns of Diabetes Mellitus patients (30%) have` less physical activity.
TREN KEJADIAN KERACUNAN MAKANAN DIBERBAGAI WILAYAH DI INDONESIA TAHUN 2014 DAN TAHUN 2015 Rhomadhoni, Muslikha Nourma; Firdausi, Nurul Jannatul; Herdiani, Novera
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 2 No 1 (2018): Medical Technology and Public Health Journal March 2018
Publisher : UNUSA Press

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Food poisoning is a condition that arises from consuming foods that contain toxins, for example: mushrooms, shellfish, pesticides, milk, toxic materials due to food and bacteria decomposition. WHO reports that approximately 70% of diarrhea cases in developing countries are caused by contaminated food that is mostly from food in catering and restaurant. In the United States poisoning cases occur in 20% in restaurants, 3% in the food industry. In Europe the source of contamination is 46% from home, restaurant / hotel (15%), 8% banquet, health facility and canteen respectively 6% and school 5%. Incidence of risk of poisoning increased due to microbial factors, host factors and factors related to diet. In Indonesia through the Drug and Food Control Agency (BPOM) has been inventoried poisoning events through online news in one year. This study aims to determine the trend of food poisoning incidence in various regions in Indonesia 2014 and 2015. By identifying the number of food poisoning events in 2014, identify the causes of poisoning events in 2014, identify the number of incidents of food poisoning in 2015, identify the causes of poisoning events in 2015, Analyzing the trend of food poisoning events in 2014 and 2015. Toxicity identification results in 2014 contained 186 total occurrences. The 2015 poisoning identification results contained 153 total incidents, with various causal factors, ranging from food, natural toxins, pesticides, mixtures, and environmental pollution. Incidence of poisoning in 2014-2015 decreased 28% in one year. In 2014 there were a total of 186 events and by 2015 there were a total of 153 events.
SOSIALISASI JAJANAN SEHAT SEBAGAI UPAYA PERBAIKAN STATUS GIZI PADA ANAK SEKOLAH DASAR DI SD MIFTAKHUL ULUM RUNGKUT SURABAYA Adriansyah, Agus Aan; Herdiani, Novera; Wijaya, Satriya
JURNAL PENGEMBANGAN KOMUNITAS Vol 1 No 1 (2017): July
Publisher : JURNAL PENGEMBANGAN KOMUNITAS

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Jajanan yang dijual pedagang keliling sering berada di depan lingkungan sekolah. Badan Pengawasan Makanan dan Minuman menyatakan terdapat 40% jajanan tidak layak dimakan. Kandungan boraks, serta formalin masih mendominasi kandungan zat-zat berbahaya pada jajanan anak-anak di sekolah-sekolah. Jajanan di sekolah memang beranekaragam dan lebih menarik minat daripada bekal yang dibawa dari rumah. Namun jajanan yang menarik tersebut justru miskin gizi dan jauh dari kata sehat. Berkaitan dengan fenomena tersebut, maka perlu adanya sosialisasi mengenai macam-macam, pengolahan, dan kelayakan konsumsi jajanan yang banyak dijual agar anak-anak dapat mengerti sehingga dapat memilih dan membedakan antar jajanan yang sehat dan tidak. Pengabdian masyarakat ini bertujuan untuk menambah pengetahuan dan kepedulian pada siswa untuk lebih memperhatikan berbagai macam jajanan yang dijual bebas demi menjaga status gizi pada masa anak-anak. Manfaat dari kegiatan ini adalah diharapkan dapat meningkatkan pengetahuan dan kepedulian seluruh siswa dalam memilih makanan atau jajanan yang sehat dan bergizi guna pendukung perkembangan generasi muda penerus bangsa yang dapat memajukan bangsa. Kegiatan intervensi yang dilakukan dengan dua metode yakni pelaksanaan sosialisasi perilaku bahaya membeli jajanan sembarangan di lingkungan SD Miftakhul Ulum Surabaya dan melakukan demo bagimana cara membuat jajanan yang sehat, bergizi, dan baik untuk perkembangan dan pertumbuhan anak. Kegiatanintervensi yang dilakukan disertai dengan pemberian pretest dan posttest. Sedangkan untuk memberikan pengetahuan kepada orangtua tentang informasi jajanan sehat, setiap siswa diberi brosur agar orangtua juga ikut mengawasi anaknya agar tidak membiarkan anak membeli jajan sembarangan. Di akhir kegiatan, setiap peserta melakukan kegiatan pengukuran tinggi dan berat badan untuk melihat status gizi mereka. Sasaran sosialisasi jajanan sehat adalah siswa SD Miftakhul Ulum Surabaya kelas 6A, 6B dan 6C secara langsung, serta guru maupun kepala sekolah secara tidak langsung. Hasil yang diperoleh pada kegiatan pengabdian masyarakat ini adalah peserta sosialisasi jajanan sehat merupakan siswa/siswi kelas 6 SD Miftakhul Ulum Surabaya dengan jumlah keseluruhan adalah 81 siswa/siswi. Sebagian besar merupakan siswa/siswi yang berusia 12 tahun (56,80%), sebagian besar berjenis kelamin laki-laki (55,60%). Peserta paling banyak adalah peserta dengan tinggi badan 130-140 cm (37,00%), dan berat badan 31-40 kg (46,90%). Berdasarkan penilaian BMI sebagian besar memiliki berat badan yang rendah (56,80%). Hasil evaluasi menurut penilaian pre test dan post test diketahui sebagian besar memiliki pengetahuan yang tetap (58,00%). Anak laki-laki lebih memiliki masalah pada status gizinya. Anak laki-laki sering mengalami berat badan rendah dan juga mengalami berat badan berlebih daripada anak perempuan. BMI anak laki-laki pada masa pra-sekolah menurun dan sejalan dengan bertambahnya usia maka BMI nya meningkat. Apapun jenis kelamin seseorang, bila dia masih produktif, berpendidikan, atau berpengalaman maka dia akan cenderung mempunyai tingkat pengetahuan yang tinggi. Rata-rata nilai evaluasi posttest lebih baik daripada pretest. Hal ini menandakan adanya efektivitas sosialisasi dalam meningkatkan pengetahuan.
PELATIHAN PEMBUATAN BEKAL SEHAT SECARA MANDIRIBAGI ANAK USIA SEKOLAH DI SDN MARGOREJO V SURABAYA Handayani, Dwi; Herdiani, Novera; Ayu, Friska
JURNAL PENGEMBANGAN KOMUNITAS Vol 2 No 1 (2018): August
Publisher : JURNAL PENGEMBANGAN KOMUNITAS

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Keamanan pangan jajanan berperan penting dalam pertumbuhan dan perkembangan anak sekolah. Kondisi lingkunganSDN Margorejo V Surabayabanyak terdapat penjual jajanandengan kualitas produk olahannya yang kurang baik. Selain itu masih sedikit anak sekolah yang membawa bekal sendiri dari rumah. Oleh sebab itu, perlu adanya penyuluhan tentang pemilihan jajanan sehat dan pelatihan pembuatan bekal sehat secara mandiri kepada siswa sekolah dasar. Kegiatan ini bertujuan menambahpengetahuan dan meningkatkan partisipasi siswa untuk menyediakan bekal sehat secara mandiri. Kegiatan dalam pengabdian masyarakat, yaitu pengukuran pengetahuan sebelum dan sesuda intervensi (pre-post test). Intervensi berupa penyuluhan jajanan. Hasil penilaian pengetahuan peserta sosialisasi (sebelum-sesudah) diketahui sebagian besar para peserta mengalami peningkatan pengetahuan mengenai jajanan sehat (56,1%). Setelah itu dilakukan pelatihan pembuatan bekal sehat dan pemberian buku resep menu bekal sehat kepada orang tua. Sebagian besar siswa (89,0%) menyukai metode praktik langsung, karena lebih mudah dipahami dan berkeinginan mencoba membuat bekal sehat bersama orang tuanya di rumah. Pihak sekolah perlu mendukung gerakan membawa bekal sehat melalui kebijakan/peraturan dan pemenuhan fasilitas kantin sehat. Kegiatan tersebut juga perlu didukung oleh partisipasi orang tua.