Nurlaila Ayu Purwaningsih, Nurlaila Ayu
Articles
2
Documents
‚Äč
Antiinflamatory Activity Test N-Hexane Extract of Breadfruit Leaf (Artocarpus altilis) for Erythema on Skin White Rat (Rattus novergiccus)

Journal of Agromedicine and Medical Sciences Vol 2, No 3 (2016)
Publisher : Medical Faculty of Jember University (Fakultas Kedokteran Universitas Jember)

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Abstract

Ultraviolet radiation (UV) is part of a spectrum of electromagnetic radiation emitted by the sun. UV-C has the shortest wavelength than the wavelength of UV-A and UV-B. UV-C is able to penetrate the earth due to the reduction of ozone in the stratosphere and is capable of causing skin cancer. The initial symptoms of cancer of skin erythema. Researchers used the N-Heksane extract of leaves of breadfruit for the treatment of erythema skin white rat (Rattus novergiccus) were exposed to UV-C radiation for 168 hours. Rats were divided into two groups of control and three experimental groups. The control group was not given the therapy and were treated dexamethasone 1 mg / kg / day while the experimental group was given the extract N-Heksane leaves of breadfruit (Artocarpus altilis) at a dose of 50 mg / kg / day, 100 mg / kg / day and 200 mg / kg /day. The method used is pure experimental (true experimental design) in vivo by design pretest-posttest control group design. Results are extensive changes erythema and ultrastructural changes in the epidermis and dermis rats were observed microscopically before and after therapy in rats irradiated skin UV-C light.Keywords: N-Hexane Extract Leaves Breadfruit (Artocarpus altilis), rat (Rattus novergiccus), UV-C radiation

The Correlation between HIV/AIDS Positive Pregnant Mother with Infant APGAR Score in RSD dr. Soebandi Jember

Journal of Agromedicine and Medical Sciences Vol 4 No 3 (2018)
Publisher : Medical Faculty of Jember University

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Abstract

Human Immunodeficiency Virus (HIV) is a virus that decreased immunity and a set symptoms of diseases called Acquired Immune Deficiency Syndrome (AIDS). One of the major risk factors for HIV transmission is perinatal transmission about 2.8% during pregnancy, delivery, and postpartum. HIV positive mothers have a potential to give birth infants with low APGAR. APGAR Score was used as a reference to determine asphyxia in the first and fifth minutes of life. The purpose of this research were to determine the correlation between HIV/AIDS positive pregnant mother with infant APGAR Score and to determine the other factors that affect the infant APGAR Score in RSD dr. Soebandi Jember. This research used observational analytic survey method with cross sectional design using medical record of HIV positive and negative pregnant women from August 2014-July 2017 in RSD dr. Soebandi Jember as a subject that qualify the inclusion and exclusion criteria. This research used case group sampling technique by total sampling and control group by simple random sampling each 52 samples. Test result of the correlation between HIV/AIDS positive pregnant mother with infant APGAR Score using Chi-Square test obtained p value=1.000 (OR=1.13) that means there was no significant correlation. Test result of the correlation between the other factors that affect infant APGAR Score concluded that there were no significant correlation. Keywords: pregnant mother, HIV/AIDS, APGAR Score, infant