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THE CLINICAL PROFILES OF AVIAN INFLUENzA IN ENDEMIC AND NON-ENDEMIC REGIONS IN INDONESIA. HOSPITAL-BASED STUDIES AND ITS IMPLICATION ON CLINICAL MANAGEMENT IN THE FUTURE Wibisono, Muhammad Jusuf; Meliana, Resti Yudhawati
Indonesian Journal of Tropical and Infectious Disease Vol 1, No 3 (2010)
Publisher : Institute of Topical Disease

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (974.019 KB) | DOI: 10.20473/ijtid.v1i3.2192

Abstract

Indonesia is a greatest burden country of H5N1 avian influenza (AI) virus infection in the world, since first outbreak in Central Java 2005 until August 2010 there was 168 confirmed cases and 138 dead cases. The incidence increasing rapidly in widespread area endemic in Java, Sumatera, Bali and Sulawesi, and sporadic outbreaks in other areas. The World Health Organization stated that AI still became a treat in the next pandemic. H5N1 AI virus infection spreads in almost all provinces, but its endemic in Jakarta, Tangerang and Banten and in other area such Surabaya, Bali were sporadic outbreaks. There are 27 confirmed H5N1 AI infection cases in Jakarta from 296 suspected cases, while in Surabaya only 5 confirmed H5N1 AI infection cases from 12 suspected cases. The age of patient mean with H5N1 AI infection was 16.9 ± 11.6 yo in Jakarta and 24 ± 8.51 yo in Surabaya. There was no difference between male and female. Mortality rate was 77.7% in Jakarta and 60% in Surabaya. A large number of case has indirect contact history, predominantly by visiting market or areas where outbreaks of poultry disease. The clinical feature H5N1 AI virus infection could manifest as mild until severe pneumonia that often progress rapidly to ARDS. In Jakarta, 74% case showed abnormality chest radiography as bilateral pneumonia, while in Surabaya showed lobar pneumonia and bilateral pneumonia. Management patient of H5N1 AI infection is supportive therapy and antiviral, whereas a large number of cases needed mechanical ventilator support.
Primary Pulmonary Lymphoma with Superior Vena Cava Syndrome Rosyid, Alfian Nur; Meliana, Resti Yudhawati
Biomolecular and Health Science Journal Vol 1, No 2 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.449 KB) | DOI: 10.20473/bhsj.v1i2.9858

Abstract

Primary Pulmonary Lymphoma (PPL) is a clonal proliferation of lymphoid cells that involve one or two lungs (parenchyma and or bronchi. PPL is found in approximately 0.4% of all lymphoma cases and 3.6% of NHL cases. Five years survival rate at stage I and II is 90%, and 80% in stage III and IV. A 63-year-old male farmer presented with chief complaint of shortness of breath for one week before admission and preceded by coughing for a month, loss of appetite and night sweating. There was an abnormal physical examination on the right side of the chest with non-tender lymph node enlargements in the right supraclavicular and neck region and superior vena cava syndrome. CT guided FNAB suggesting NHL. Patient was treated with CHOP chemotherapy regiment. However, with high grade lymphoma, patient did not respond well.