Jenny Sunariani, Jenny
Unknown Affiliation

Published : 10 Documents
Articles

Found 2 Documents
Search
Journal : Indonesian Journal of Tropical and Infectious Disease

THE EFFECTS OF NICOTINE ON THE PERIODONTAL TISSUE Herawati, Herawati; Sunariani, Jenny
Indonesian Journal of Tropical and Infectious Disease Vol 1, No 3 (2010)
Publisher : Institute of Topical Disease

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (314.992 KB) | DOI: 10.20473/ijtid.v1i3.2199

Abstract

Tobacco contains thousands of chemical substances which known to be harmful to periodontal tissues. Nicotine was considered as the most toxic substances to periodontal tissues. The datas in this review indicate that smoking may have a significant role in the initiation and progression of periodontal destruction. The conclusion of this and the other studies indicate that smokers have a less favorable response to periodontal therapy than non smoker. Nicotine is potentially toxic substances that have a detrimental effect on periodontal tissue, by altering the host response or directly damage the cells of normal periodontium.
MECHANISMS OF PERIODONTITIS - INDUCED ATHEROSCLEROSIS Hudyono, Rikko; Sunariani, Jenny
Indonesian Journal of Tropical and Infectious Disease Vol 1, No 3 (2010)
Publisher : Institute of Topical Disease

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (691.999 KB) | DOI: 10.20473/ijtid.v1i3.2197

Abstract

Nowadays CVD become the most common cause of death in US and worldwide. Atherosclerosis plays an important role in CVDs pathogenesis. Atherosclerosis decreases the elasticity of the vascular. Atherosclerosis shares the same risk factor as CVD, in which obesity, hyperlipidemia, hypertension and lack of physical activity may initiate it. However, 50% of all CVD patients are lack of the usual causes of CVD. The purpose of this review is to reveal the mechanism of periodontitis-induced atherosclerosis. Inflammation and autoimmune disease might play an important role in initiate the CVD. Periodontitis is one of the oral diseases which can cause systemic inflammation and may induce the atherosclerosis. Porphyromonas gingivalis (Pg) which is the major cause of periodontitis can induce it by expressing protein gp130 in its fimbriae. Periodontics patients are prone to have bacteremia by daily routine oral hygiene activity. Chronic bacteremia may alter the endothelial physiology, which is resulted in neointima formation, EC dysfunction, and lipid accumulation. It is concluded that periodontitis may play an important role in initiation and progression of atherosclerosis.