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Stress, Nutritional Status and Blood Glucose Levels among Patients with Diabetes Mellitus Type 2 Wardani, Dyah Ayu Kusuma; Sugiarto, Sugiarto; Cilmiaty, Risya
International Journal of Public Health Science (IJPHS) Vol 7, No 4: December 2018
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/10.11591/ijphs.v7i4.14914

Abstract

Prevalence of diabetes mellitus (DM) was increased significantly. Stress increased cortisol could increase blood glucose levels while obesity could increase insulin resistance. Objective of this study was to examine correlation of stress and nutritional status with blood glucose levels in patients with DM type 2. Design study was cross sectional using 120 samples from patients with DM type 2 at Polyclinic of Internal Disease Dr. Moewardi Hospital Surakarta during April-May 2018. Variables in this study were stress with perceived stress scale 10 items (PSS-10), nutritional status with body mass index (BMI) and blood glucose levels with fasting blood glucose (FBG) and post-prandial blood glucose (PPBG) examination. The results showed that mean of FBG was 152.9±63.66 mg/dL and PPBG was 213.96±70.17 mg/dL. There was no significant correlation between stress and blood glucose levels, by FBG (p=0.389) and PPBG (p=0.202). However, there was significant correlation between nutritional status and PPBG (p=0.016), but FBG was not significant (p=0.209). In conclusion, there was significant correlation between nutritional status and PPBG in patients with DM type 2, but FBG was not significant. However, there was no significant correlation between stress and blood glucose levels in patients with DM type 2.
Prevotella intermedia and Porphyromonas gingivalis in dental caries with periapical granuloma Cilmiaty, Risya; Prasetyo, Afiono Agung; Zaini, Khilyat Ulin Nur; Rukmo, Mandojo; Putra, Suhartono Taat; Asmara, Widya
Dental Journal (Majalah Kedokteran Gigi) Vol 46, No 4 (2013): (December 2013)
Publisher : Faculty of Dental Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v46.i4.p213-217

Abstract

Background: Dental caries with necrotic pulp is a multifactorial disease that attacks enamel involving tooth pulp. The anaerobic bacteria infection in the pulp chamber could induce the formation of periapical granuloma. However, the presence of the most frequently anaerobic bacteria identified in apical periodontitis, Porphyromonas gingivalis and Prevotella intermedia, in periapical granuloma have not been confirmed. Purpose: The aims of study were to determine the presence of Porphyromonas gingivalis and Prevotella intermedia in dental caries with necrotic pulp and to determine its relation to periapical granuloma. Methods: Thirty-six patients of dental caries with necrotic pulp in Dr. Moewardi General Hospital in Surakarta, Indonesia were involved and classified into two groups, the group of patients with periapical granuloma and the group of patients without periapical granuloma. The caries tooth was extracted, and the chronic periapical tissue was swabbed and cultured on blood agar medium in anaerobic condition. The bacterial DNA was extracted from the positive cultures and subjected for Polymerase Chain Reaction (PCR). Results: Periapical granuloma was more likely found in women (OR 5.5, 95% CI=1.277-23.693; RR 2.5, 95% CI= 1.025-6.100). Black colonies bacteria were associated with periapical granuloma (OR 2.2, 95% CI=0.517-9.594; RR 1.5, 95% CI=0.655-3.623). Porphyromonas gingivalis and Prevotella intermedia were detected in group with or without periapical granuloma, however, only Prevotella intermedia was associated with periapical granuloma (OR 1.6, 95% CI=0.418-5.903; RR 1.3, 95% CI=0.653-2.393). Conclusion: The presence of Porphyromonas gingivalis and Prevotella intermedia in periapical granuloma were confirmed, however, only Prevotella intermedia were associated with periapical granuloma.Latar belakang: Karies gigi dengan pulpa nekrosis adalah penyakit multifaktorial yang menyerang enamel hingga ruang pulpa gigi. Infeksi bakteri anaerob di pulpa nekrosis dapat menginduksi pembentukan granuloma periapikal. Namun, keberadaan bakteri anaerob yang paling banyak ditemukan di periodontitis apikal, Porphyromonas gingivalis dan Prevotella intermedia, di granuloma periapikal masih perlu diteliti . Tujuan: Penelitian ini bertujuan meneliti keberadaan bakteri Porphyromonas gingivalis dan Prevotella intermedia, di karies gigi dengan pulpa nekrosis dan menganalisis kaitannya dengan granuloma periapikal. Metode: Tiga puluh enam pasien karies gigi dengan pulpa nekrosis di Rumah Sakit Umum Dr. Moewardi di Surakarta Indonesia dilibatkan dan diklasifikasikan dalam dua kelompok yaitu kelompok pasien dengan granuloma periapikal dan kelompok pasien tanpa granuloma periapikal. Gigi karies diekstraksi dan jaringan periapikal kronis diusap dan dikultur di media agar darah dalam kondisi anaerob. DNA bakteri diekstrak dari kultur yang positif dan dilakukan pemeriksaan dengan Polymerase Chain Reaction (PCR). Hasil: Granuloma periapikal lebih banyak ditemukan pada wanita (OR 5,5, 95% CI= 1,277-23,693; RR 2,5, 95% CI= 1,025-6,100). Koloni bakteri berwarna hitam diasosiasikan dengan granuloma periapikal (OR 2,2, 95% CI= 0,517-9,594; RR 1,5, 95% CI= 0,655-3,623). Porphyromonas gingivalis dan Prevotella intermedia terdeteksi di jaringan karies dental dengan atau tanpa granuloma periapikal, namun hanya Prevotella intermedia yang diasosiasikan dengan granuloma periapikal (OR 1,6, 95% CI= 0,418-5,903; RR 1,3, 95% CI= 0,653-2,393). Simpulan: Porphyromonas gingivalis dan Prevotella intermedia ditemukan di granuloma periapikal, namun hanya Prevotella intermedia yang terkait langsung dengan granuloma periapikal.
The role of Hsp0, CD-8 and IFN-γ in immunopathobiogenesis of periapical granuloma in dental caries Cilmiaty, Risya; Rukmo, Mandojo
Dental Journal (Majalah Kedokteran Gigi) Vol 47, No 1 (2014): (March 2014)
Publisher : Faculty of Dental Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v47.i1.p7-12

Abstract

Background: The incidence of dental caries with periapical granulomas in Indonesia is quite high. However, the mechanism of the formation of periapical granulomas in dental caries caused by bacterial infection in immunopathobiogenesis cannot be explained completely. Thus, this explanation is necessary in order to be used as a basis for diagnostic, preventive and therapeutic measures. Purpose: This research was aimed to determine the role of Hsp60, CD-8 and IFN-γ in immunopatobiogenesis of periapical granuloma in dental caries. Methods: This research was an analytic observational study with cross sectional approach. Samples of this research were 36 teeth of patients with dental caries, consisting of 18 caries teeth with periapical granulomas and 18 caries teeth without periapical granulomas. The variables observed in this research were Hsp60, CD-8 and IFN-γ. Measurements were conducted by using immunohistochemical methods on periapical tissue. Results: The mean of Hsp60, CD-8 and IFN-γ in granuloma group was significantly higher than those in non granuloma group (p<0.05). The positive role of IFN-γ on the incidence of granulomas appeared to be more prominent. Conclusion: The study suggested that in immunopathobiogenesis of periapical granuloma in dental caries, Hsp60, CD-8 and IFN-γ played important roles, but the role of IFN-γ was found to be more prominent.Latar belakang: Angka kejadian gigi karies dengan granuloma periapikal di Indonesia cukup tinggi, Namun mekanisme terbentuknya granuloma periapikal pada gigi karies yang disebabkan oleh infeksi bakteri secara imunopatobiogenesis belum dapat dijelaskan secara tuntas. Adanya penjelasan ini diperlukan agar dapat digunakan sebagai dasar pengembangan diagnosis, langkah preventif dan terapinya. Tujuan: Penelitian ini bertujuan untuk mengetahui peran Hsp60, CD-8 dan IFN-γ dalam immunopatobiogenesis dari granuloma periapikal karies gigi. Metode: Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross sectional. Sampel dari penelitian ini adalah 36 gigi pasien dengan karies, yang terdiri dari 18 karies gigi dengan granuloma periapikal dan 18 karies gigi tanpa granuloma periapikal. Variabel yang diamati adalah Hsp60, CD-8 dan IFN-γ. Pengukuran dilakukan dengan menggunakan metode imunohistokimia pada jaringan periapikal. Hasil: Rerata Hsp60, CD-8 dan IFN-γ pada kelompok granuloma secara signifikan lebih tinggi dibanding kelompok non granuloma (p <0,05). Peran positif dari IFN-γ terhadap kejadian granuloma tampaknya lebih menonjol. Simpulan: Studi ini menunjukkan bahwa dalam imunopatobiogenesis dari granuloma periapikal karies gigi, Hsp60, CD-8 dan IFN-γ memainkan peran penting, tetapi peran IFN-γ ditemukan lebih menonjol.
HUBUNGAN BEBERAPA FAKTOR DENGAN STUNTING PADA BALITA BERAT BADAN LAHIR RENDAH Lubis, Frienty Sherlla Mareta; Cilmiaty, Risya; Magna, Adi
Jurnal Kesehatan Kusuma Husada Vol. 9 No. 1, Januari 2018
Publisher : STIKes Kusuma Husada Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34035/jk.v9i1.254

Abstract

Stunting merupakan salah satu masalah gizi yang utama pada anak di Indonesia. Stunting menjadi masalah yang serius karena dikaitkan dengan kualitas sumberdaya manusia di kemudian hari. Anak dengan BBLR(Berat Badan Lahir Rendah) beresiko lebih tinggi menjadi stunting. Tujuan untuk mengetahui hubungan antara IMD (Inisiasi Menyusu Dini), dan BBLR dengan stunting pada anak usia 12-24 bulan dengan berat badan lahir rendah. Jenis penelitian adalah observasional analitik dengan menggunakan desain penelitian cross-sectional. Subjek penelitian ditentukan dengan purposive sampling. Subjek terdiri dari 82 balita yang berusia 12-24 bulan dengan BBLR di 2 kecamatan di Kota Surakarta. Pengumpulan data dilakukan dengan wawancara langsung dan pengukuran antropometri. Uji statistik Chi-square digunakan untuk menganalisis hubungan antara variabel IMD dengan stunting dan uji Anova digunakan untuk menganalisis hubungan antara variabel BBLR dengan stunting. Hasil: IMD tidak berhubungan signifikan dengan kejadian stunting (X² = 0,286, p = 0,593), berat badan lahir rendah (BBLR) berhubungan signifikan dengan kejadian stunting pada α 10 % ( F = 1,561, p = 0,087). Kesimpulan: ada hubungan antara Berat Badan Lahir Rendah dengan Kejadian Stunting. Stunting is one of the main nutritional problems in children in Indonesia. Stunting becomes a serious problem because it is associated with the quality of human resources in the future. Children with LBW (Low Birth Weight) are at higher risk of becoming stunting. Objective: To know the relationship between IMD, and LBW with stunting in children aged 12-24 months with low birth weight. The type of research is observational analytic by using cross-sectional research design. Research subject is determined by purposive sampling. Subject consisted of 82 children aged 12-24 months with LBW in 2 districts in Surakarta. Data collection is done by direct interview and anthropometry measurement. Chi-square statistical test is used to analyze the relationship between IMD variable with stunting and Anova test is used to analyze the relationship between LBW variable with stunting. The result: IMD was not significantly associated with stunting incidence (X² = 0.286, p = 0,593), low birth weight (LBW) was significantly associated with stunting incidence at α 10% (F = 1.561, p = 0.087). Conclusion: there is a relationship between Low Birth Weight with Stunting Event.
Pendidikan Kesehatan Gigi dan Mulut serta Praktek Menggosok Gigi Pada Anak Berkebutuhan Khusus (ABK) Saptiwi, Betty; Cilmiaty, Risya; Susanti, Widia; Handayani, Selfi
ABDIMAS UNIVERSAL Vol 1 No 2 (2019): Oktober
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Balikpapan (LPPM UNIBA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36277/abdimasuniversal.v1i2.35

Abstract

Special Needs Children in SLB Anugerah, Colomadu, Karanganyar, Central Java, are still difficult to practice how to brush teeth correctly and still lack of understanding of oral health, so that the hygiene and dental health status and mouth are still lacking. Therefore it is necessary to fix it. The purpose of this activity is to carry out one component of the Higher Education Tri Dharma that is community service. The benefits of this service are for special needs students to increase their knowledge about oral health and improve their skills in brushing their teeth properly. The dedication method is a lecture on how to maintain dental and oral health as well as the practice of brushing teeth along with the target audience, all Special Needs Children in SLB Anugerah, Colomadu, Karanganyar. A total of 52 people were present. The results of the dedication showed that 42.3% of the targets were able to practice brushing teeth with enough categories and 57.7% were still in the poor category. Meanwhile, no one has been categorized as good. The conclusion of this dedication is, the practice of brushing Special Needs Children teeth in SLB Colomadu, Karanganyar is still in the category of sufficient and insufficient so that it is necessary to follow up this service activity by involving parents at home in monitoring the maintenance of dental and oral health of Special Needs Children.