Yuli Hermansyah, Yuli
Fakultas Kedokteran Universitas Jember

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Efek Ekstrak Air Kulit Buah Delima (Punica granatum L) terhadap Salmonella typhimurium secara In Vivo (The Effect of Pomegranate (Punica granatum L) Peel Aqueous Extract on Salmonella typhimurium In Vivo) Purwani, Anastasia Citra; Agustina, Dini; Hermansyah, Yuli
Pustaka Kesehatan Vol 3, No 2 (2015)
Publisher : Pustaka Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (218 KB)

Abstract

Salmonella typhi infection is commonly treated by an antimicrobial agent such as levofloxacin. At the moment, herbal usage has risen as an alternative therapy. Pomegranate (Punica granatum L) is a commonly used herb which contains flavonoid as its major active compound. Aqueous extract of pomegranate peel had been known for its antimicrobial effect to S. typhi on in vitro study. The aim of this research was to investigate the activity of aqueous extract of pomegranate peel to S. typhimurium in vivo and find the antimicrobial effect of different concentrations. The study was conducted by using typhoid fever model in mice infected by S. typhimurium. Each mice was treated with aqueous pomegranate peel extract in three consentrations: 0,65 mg/ml, 1,3 mg/ml and 2,6 mg/ml for treatment groups and levofloxacin 1,3 mg/ml for positive control group. Ileum of each mice was isolated and cultured. The result of post hoc LSD test showed that negative control group significantly different with treatment group and the result of Pearson test showed p=0,000 and r = -0,865. In conclusion, aqueous extract of pomegranate peel had an antimicrobial activity on S. typhimurium in vivo where the higher extract concentration the lesser number of S. typhimurium colony.   Keywords: Antimicrobial, Pomegranate, Salmonella typhimurium
Efek Ekstrak Air Kulit Buah Delima (Punica granatum L) terhadap Salmonella typhimurium secara In Vivo (The Effect of Pomegranate (Punica granatum L) Peel Aqueous Extract on Salmonella typhimurium In Vivo) Purwani, Anastasia Citra; Agustina, Dini; Hermansyah, Yuli
Pustaka Kesehatan Vol 3 No 2 (2015)
Publisher : UPT Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (218 KB)

Abstract

Salmonella typhi infection is commonly treated by an antimicrobial agent such as levofloxacin. At the moment, herbal usage has risen as an alternative therapy. Pomegranate (Punica granatum L) is a commonly used herb which contains flavonoid as its major active compound. Aqueous extract of pomegranate peel had been known for its antimicrobial effect to S. typhi on in vitro study. The aim of this research was to investigate the activity of aqueous extract of pomegranate peel to S. typhimurium in vivo and find the antimicrobial effect of different concentrations. The study was conducted by using typhoid fever model in mice infected by S. typhimurium. Each mice was treated with aqueous pomegranate peel extract in three consentrations: 0,65 mg/ml, 1,3 mg/ml and 2,6 mg/ml for treatment groups and levofloxacin 1,3 mg/ml for positive control group. Ileum of each mice was isolated and cultured. The result of post hoc LSD test showed that negative control group significantly different with treatment group and the result of Pearson test showed p=0,000 and r = -0,865. In conclusion, aqueous extract of pomegranate peel had an antimicrobial activity on S. typhimurium in vivo where the higher extract concentration the lesser number of S. typhimurium colony.   Keywords: Antimicrobial, Pomegranate, Salmonella typhimurium
The Correlation Between Carbohydrate Consumption with Blood Pressure Levels of Elderly Communities in Sumbersari Jember Cinintya, Revin Fiona; Rachmawati, Dwita Aryadina; Hermansyah, Yuli
Journal of Agromedicine and Medical Sciences Vol 3, No 1 (2017)
Publisher : Medical Faculty of Jember University (Fakultas Kedokteran Universitas Jember)

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Abstract

The increasing population of elderly causes getting more complex illness because impairment in  organ function, one of them is the blood vessels. Blood vessels will have decreased nitrite oxide that causes atherosclerosis, as the primary cause of the hypertension. The change of lifestyle and nutrient factor is related to the incident of hypertension. Meanwhile, Indonesians tend to prefer food sources of carbohydrate. The purpose of this research is to analyze relations between consumption of carbohydrate with blood pressure on elderly from active members of Karang Wreda Sriwijaya and Semeru Jaya Sumbersari Jember about 47 samples. This research is an analytic observational research with the cross sectional methods. In this research, samples were interviewed to describe the charracteristic ( the age, sex, the history of hypertension). Then samples were interviewed to know their carbohydrate consumption using 24-hours Food Recall method three times in different time with the maximum of two weeks and the blood pressure was checked with a mercurial sphygmomanometer. The results of this research based on the correlation of Spearman obtained a value of p=0,00 for the number of subject’s carbohydrates consumption with systolic blood pressure and p=0,02 for diastolic pressure. The conclusion is there is a correlation between carbohydrates consumption with systolic and diastolic blood pressure.Keywords: carbohydrates consumption, blood pressure, elderly  
The Effect of Hemodialysis on Kinetic Segment of Left Ventricular in Stage V Chronic Kidney Diseases Patients Kamasita, Systriana Esi; Suryono, Suryono; Nurdian, Yudha; Hermansyah, Yuli; Junaidi, Edy; Fatekurohman, Mohamat
NurseLine Journal Vol 3 No 1 (2018): Mei 2018
Publisher : Faculty of Nursing, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/nlj.v3i1.6506

Abstract

Chronic kidney disease (CKD) stage V attacks other organs such as heart that can cause cardiovascular disease (CVD). One of them is CVD caused by CKD stage V that is the kinetic segment of left ventricle. Cardiovascular disease occurs due to excess fluid and buildup of uremic toxin. Chronic kidney disease stage V can not be cured so it requires therapy that is hemodialysis (HD). Hemodialysis can reduce excess fluid, uremic toxin, and maintain electrolyte balance in stage V stage. Improved fluid and decreased uremic toxin can reduce the burden of the heart and strain so that blood supply to certain myocardial areas increases and the left ventricular kinetic segment increases. The purpose of this study is to determine the effect of HD on left ventricular kinetic changes in CKD stage V patients in dr. Soebandi hospital in Jember. The research design used was quasi-experimental one group pretest-postest design. The sample was 30 patients. Respondents were determined by nonprobability sampling technique with purposive sampling method. The data used are primary data and secondary data. Data analysis using Wilcoxon test. Based on the results of the study, the distribution of the sample based on the age of the most in the range of 45-54 years, based on the sex obtained more women, based on the duration of hemodialysis obtained the period of most hemodialysis> 24 months and based on blood pressure before and after hemodialysis obtained patients with hypertension. Hypothesis test using Wilcoxon test got p-value (0.000). From the results of the analysis can be concluded that there is influence of hemodialysis on kinetic segment of left ventricle in patient of CKD stage V in dr. Soebandi hospital in Jember.   
Hemodialysis Effect on Systolic Left Ventricular Function in Stage V Chronic Kidney Disease Patients Ramadhan, Hazbina Fauqi; Hermansyah, Yuli; Wisudanti, Desie Dwi; Suryono, Suryono
Journal of Agromedicine and Medical Sciences Vol 4 No 3 (2018)
Publisher : Medical Faculty of Jember University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v4i3.6543

Abstract

Chronic kidney diasease (CKD) is one of world health problem with increased incidence. Kidney function impairment contribute to cardiovascular complication that has been the main cause of CKD patient death. The impairment of cardiovascular function mainly caused by decreased of systolic left ventricular function. Stage V CKD patients need renal replacement therapy such as hemodialysis. Hemodialysis known to has positive effect on cadiovascular function by decreasing volume overload and uremic toxin. Echocardiography is a non-invasive method to assess cardiovascular function i.e. systolic left ventricular function. The aim of this study is to describe the improvement of  systolic left ventricular function in stage V CKD patients after going through hemodialysis. The subject of this study are 30 patients, ≥18 years old diagnosed with Stage V CKD and undergo routine hemodialysis in RSD dr. Soebandi Jember. The data analyzed with Wilcoxon test and shown significance (p=0,000). This study concludes there is a significant improvement on systolic left ventricular function in CKD patients before and after hemodialysis in RSD dr. Soebandi Jember. Keywords: Systolic Left Ventricular Function, Hemodialysis, Chronic Kidney Disease, Echocardiography
Uji Aktivitas Fraksi Diklorometana Ekstrak Metanol Bangle (Zingiber cassumunar Roxb.) sebagai Terapi Komplementer Malaria secara In Vivo (The Activity Test of Dichloromethane Fraction of Bangle (Zingiber cassumunar Roxb.) Methanolic Extract as Complement Rachmadenawanti, Edda; Hermansyah, Bagus; Hermansyah, Yuli
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Penerbitan Universitas Jember

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Abstract

World Malaria Report reported that Malaria threats 40% of world population in six regions and ninety seven endemic countries. This study aimed to investigate the activity of dichloromethane fraction of Bangle as a complementary therapy of malaria in vivo. This was true experimental laboratories study using 28 mice of Balb/c, divided into seven groups. Five treatment groups were given five dose of dichloromethane fraction of Bangle methanolic extracts as imunostimulant before malaria infection and during malaria therapy by combining with malaria standard therapy. K(+) group was given malaria standard therapy. K(-) group was not given any therapy after infection. Inhibition percentage of malaria parasite in K(-) was 0 and K(+) was 24,74%. The treatment group of 0,09 mg/grBW had the highest inhibition percentage, as many as 88,19%. It declined by decreasing dose of fraction. The result of pearson correlation showed very strong correlation (r=0,880). The Ic50 value of dichloromethane fraction of Bangle methanolic extract as a complementary therapy was 0,008 mg/grBW. In conclusion, dichloromethane fraction of Bangle methanolic extract had immunostimulant effect and antimalarial activity in vivo.   Key words: bangle, complementary therapy, inhibition percentage, malaria
Pengaruh Beban Kerja Fisik terhadap Tingkat Disabilitas Pasien Nyeri Punggung Bawah di RSD dr. Soebandi Jember (Influence of Workload Level on Low Back Pain Patient’s Physical Disabilities at RSD dr. Soebandi Jember) Nugroho, Imam Adi; Marchianti, Ancah Caesarina Novi; Hermansyah, Yuli
Pustaka Kesehatan Vol 5 No 2 (2017)
Publisher : UPT Penerbitan Universitas Jember

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Abstract

Disability is a condition that the patient loss of opportunities to take a part in normal life due to physical, mental and social barrier. Disability is commonly caused by low back pain. Physical workload is the one of risk factors of low back pain. The purpose of study was to measure the influence of physical workload and disability caused by low back pain at RSD dr. Soebandi Jember. This research was analytic observational study with cross sectional approach. Physical workload was measured by Self Measured Quistionere Physical Demand and disability was measured by Oswestry Disability Index. Physical workload was divided into manual handling and work postures. As many as 32 samples were collected during May-June 2016. The data were analyzed by Spearman correlations test and showed there were no significantly influence between manual handling (α=0,769), work postures (α=0.763) and disability. Spearman correlation test also showed there were no relationship between manual handling (r=0,055), work postures (r=-0,054) and disability. Thus it, can be concluded that there were no influence between physical workload and disability caused by low back pain in RSD dr. Soebandi Jember. Keywords: Low back pain, physical workload, disability