Tongku N. Siregar, Tongku
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Histopathological Change of White Mouse Ovary as a Result of Ethylene Glycol Intoxication Budiman, Hamdani; Akmal, Muslim; N. Siregar, Tongku
Jurnal Kedokteran Hewan Vol 2, No 2 (2008): J. Ked. Hewan
Publisher : Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (614.122 KB) | DOI: 10.21157/j.ked.hewan.v2i2.9782

Abstract

This research was aimed to know histopathology change of white mouse ovary as result of EG intoxication. Eight white mice randomly divided into three treatment groups and one control group. Treatment of P1 group was given 10 ml EG/L drinking water, P2 was given 20 ml EG/L drinking water, and P3 was given 30 ml EG/L drinking water for two weeks. Control group was given aquadest. Then, white mice were euthanized and ovaries sample were taken for histology observation. The result for treatment groups (P1 and P2) had shown ovary hyperemic (congest). But, the change is worst in P2 rather than P1. Changes in P3 treatment group had shown ovary hyperemic (congest) and leukocyte infiltration in follicular antrum and follicular necrosis causing lost of ovum cell (cariolysis). Poisoned of EG in white mouse can cause inflammation and necrosis of ovary follicle thus the formed of ovum cell was failed (ovogenesis).
Maturation of Nile-Tilapia (Oreochromis niloticus) Oocytes With Exposed by Goat Inhibin Isolated from Granulose Cells Linggi, Yulianus; A, Aulanni’am; Risjani, Yenni; N. Siregar, Tongku
Jurnal Kedokteran Hewan Vol 1, No 1 (2007): J. Ked. Hewan
Publisher : Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (210.88 KB) | DOI: 10.21157/j.ked.hewan.v1i1.3118

Abstract

The present study aimed to investigate the role of inhibin in the regulation of oocytesmaturation. Inhibin was isolated from goat granulose cells and injected by intraperitoneal in to femaleNile-Tilapia. Three days later its gonad was taken by decapitation and the change of oocyte was evaluatedunder microscope. Results showed that average of percentages of oocytes that undergo maturated after exposed with inhibin of 0, 20, 40, and 60µg/individual 50.05, 29.44, 21.46, and 30.83%, respectively.The exposure of doses of goat inhibin in Nile-Tilapia showed significantly different (P<0.01) to percentages of mature oocytes. It was conluded that exposition of goat inhibin from granulose cells caninducing the maturation of Nile-Tilapia oocytes.Keywords: inhibin, maturation, oocytes