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Uji in Vivo Ekstrak Etanol Daun Sambung Nyawa (Gynura procumbens) Terhadap Penurunan Kadar Gula Darah Mencit (Mus musculus) Jantan Strain Swiss Webster Diabetes Mellitus Sofia, Sofia; Rinidar, Rinidar; Mariana, Mariana
Jurnal Kedokteran Syiah Kuala Vol 11, No 3 (2011): Volume 11 Nomor 3 Desember 2011
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.651 KB)

Abstract

Abstrak. Diabetes mellitus merupakan penyakit dengan gangguan metabolisme karbohidrat yang ditandai  kadar glukosa darah yang tinggi (hiperglikemi) dan adanya glukosa dalam urin (glukosuria). Tujuan penelitian ini adalah untuk mengetahui pengaruh ekstrak etanol daun sambung nyawa (Gynura procumbens) dalam menurunkan kadar gula darah mencit (Mus musculus) jantan strain Swiss Webster yang di induksi aloksan. Desain penelitian ini adalah Rancangan Acak Lengkap (RAL) dengan 5 (lima) perlakuan (N = 25). Ekstrak etanol daun sambung nyawa diberikan secara per oral dengan dosis P1 (100 mg/kgBB), P2 (150 mg/kgBB) dan P3 (200 mg/kgBB). Kelompok kontrol positif (KP) diberi glibenklamida 10 mg/kgBB dan kelompok kontrol negatif (KN) diberi akuades 0,2 cc. Analisis Varian (ANAVA) satu arah menunjukkan bahwa terdapat perbedaan yang nyata antara kelima kelompok perlakuan terhadap penurunan kadar gula darah (p<0,05). Uji LSD menjelaskan bahwa pemberian ekstrak etanol daun sambung nyawa dosis 150 mg/kgBB (P2) dan 200 mg/kgBB (P3) menunjukkan pengaruh yang bermakna terhadap penurunan gula darah mencit diabetes mellitus yang di induksi aloksan sedangkan dosis 100 mg/kgBB (P1) tidak berpengaruh. Kesimpulan penelitian ini adalah dosis efektif dalam penurunan peningkatan kadar gula darah pada Mus Musculus strain Swiss-Webster adalah 200 mg/kgBB. Abstract. Diabetes Mellitus is a disease of carbohydrate metabolism disorder characterized by high blood glucose levels (hyperglycemia) and presence of glucose in the urine (glucosuria). The aims of this study was to determine the effect of ethanol extract of Gynura procumbens leaves in lowering blood glucose levels of Mus musculus Swiss Webster- strained induced alloxan. This study conducted using a laboratory experimental design of completely randomized design (CRD), which divided into 5(five) treatment groups (N=25). Ethanol extract of Gynura procumbens leaves were administered orally with doses of P1 (100 mg/kg BW), P2 (150 mg/kg BW) and P3 (200 mg/kg BW). Positive control group (CP) were given 10 mg/kg BW of glibenklamida and negative control groups (CN) were given 0.2 cc distilled water. One-way ANOVA showed that decreasing blood glucose levels were significantly different among the five treatment groups (p<0.05). LSD test confirmed that P2 (150 mg/kg BW) and P3 (200 mg/kg BW) were significantly different in lowering blood glucose levels (p<0.05) whether P1 (100 mg/kg BW) was not.  It concluded that the most effective dose in lowering elevated levels of blood glucose was 200 mg/kgBW.
Hubungan Kondisi Lingkungan Rumah dan Perilaku Keluarga dengan Kejadian Demam Berdarah Dengue Di Kabupaten Aceh Besar Sofia, Sofia; Suhartono, Suhartono; Wahyuningsih, Nur Endah
JURNAL KESEHATAN LINGKUNGAN INDONESIA Vol 13, No 1 (2014): April 2014
Publisher : Program Studi Magister Kesehatan Lingkungan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.263 KB) | DOI: 10.14710/jkli.13.1.30 - 38

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Background: Dengue Hemorrhagic Fever (DHF) is a communicable disease caused by dengue virus known as the most spread disease in the world. In Aceh Besar district, DHF cases were found annually, 156 cases was recorded in 2013 (IR=42,0 per100.000 people), 1 case of death was reported (CFR=0,88%). It was seen that almost household had breeding places and used materials which can trun into breading places of Aedes aegypti. This research was to analyze the relationship of household environmental condition and family behavior to the incidence of DHF. Methods: This research was observational analytic study using case control design with total samples of 150 respondents, consisted of 75 cases and 75 control. Data analysis were using Chi-Square and Logistic Regression. Results: The result was that there was significant relationship between breeding place in household (p=0,000 and OR = 5,5), temperature in house (p=0,000 and OR= 4,0) and habits of cleaning up water container (p=0,000 and OR= 4,7) to the incidence of DHF. Conclusion: Community can prevent the cycle of DHF transmission by doing activities such as egg, larva, pupa eradication in its breading places, cleaning up water container at least, once in less then 7 days and actively perform 3 M Plus activities. Coordination between various stake holders is needed to observe sanitation of environment so then breeding places will not exist for Aedes aegypti. Keywords: Residence environment, family behavior, DHF
PENGUATAN KELOMPOK TANI MELALUI OPTIMALISASI DAN SINERGI LINGKUNGAN SOSIAL Subekti, Sri; Sudarko, Sudarko; Sofia, Sofia
Jurnal Sosial Ekonomi Pertanian Vol 8, No 3 (2015): JSEP
Publisher : Jurnal Sosial Ekonomi Pertanian

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Abstract

The purpose of this research is to analyze the process of strengthening farmer groups through the optimization of environmental and social synergy in farmer groups. The results showed the strengthening of farmer groups can be grown by increasing the synergistic relationship between farmer groups with the social environment. Social environment that can support the strengthening of farmer groups are farmers, gapoktan, Department of Agricultural, Research Institute, Laboratory of pests and diseases, PPAH, financial institutions, HIPPA, traders, kiosk production facilities and universities.Keywords: farmer groups, social environmental, synergy
FAKTOR-FAKTOR YANG MENDASARI MASYARAKAT SEKITAR TAMAN NASIONAL MERU BETIRI MENGAMBIL RAFFLESIA Zollingeriana Kds. Fatmawati, Nurlela; Mustapit, Mustapit; Sofia, Sofia
JSEP (Journal of Social and Agricultural Economics) Vol 11 No 2 (2018)
Publisher : University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (360.139 KB) | DOI: 10.19184/jsep.v11i2.8615

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Rafflesia zollingeriana Kds. is the only endemic Rafflesia species in Meru Betiri National Park. The threatened status is on endangered. But, the people who resident in around of forest belief this plant have a savour in health as traditional medicine and threatened by theft. The purpose of the research is to knows a). Perceptions of the community around Meru Betiri National Park to Rafflesia zollingeriana Kds. b). Affecting factor the community take Rafflesia zollingeriana Kds. in Meru Betiri National Park area. and c). Actors involved in the activities of the Rafflesia zollingeriana Kds. This research did at Bandealit and Wonosari resort by qualitative method. The results showed that the perception of society is divided into two: economic and social aspects. On the economic aspect, people consider that this plant has a high selling value and can help increase revenue. Based on the social aspect, the daily life of the community around the area is so close from the forest. The main factor that affecting the people around Meru Betiri National Park takes Rafflesia zollingeriana kds. is a factor of economic necessity and social life. Supporting factors is couses the low knowledge of conservation efforts, Low educational, and cultural factors of society who still use traditional medicine as an alternative treatment. The actors involved in taking Rafflesia zollingeriana kds. are buyers, community takers, processors, and sellers.
Peranan Media Pengajaran dalam Pembelajaran Bahasa Sofia, Sofia
Al-Hikmah Journal for Religious Studies Vol 13, No 1 (2012)
Publisher : Fakultas Adab dan Humaniora UIN Alauddin

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Teaching language is like the adults (father-mother) teach their baby to practice speaking. Naturally, a child or a baby just imitates or repeat what the adults say. However, to accelerate and to grow up their skill in uttering the word media is needed, because it has function to make something abstract to be real and concret, as well as, to ease baby or children understand what they hear. Such this case accure in teaching and learning process where media is treated as a means of transferring knowledge. Good media leads a teacher or lecturer to good educative interactions in which it could strengthen the method of learning
Efisiensi Biaya dan Prospek Pengembangan Budidaya Tanaman Cabe Jawa Muzakki, Ahmad; Soetriono, Soetriono; Sofia, Sofia
SOROT Vol 13, No 2 (2018)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/sorot.13.2.6253

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Penelitian ini bertujuan untuk menganalisis pendapatan petani terhadap budidaya, menganalisis efisiensi biaya, dan menganalisis prospek pengembangan budidaya cabe jawa. Lokasi penelitian ditentukan dengan menggunakan purposive method, yaitu di Desa Bagorejo Kecamatan Gumukmas Kabupaten Jember. Metode penelitian yang digunakan adalah metode deskriptif dan analitik. Metode pengambilan sampel menggunakan total sampling, untuk menjawab permasalahan pendapatan dan efisiensi biaya, sedangkan purposive sampling untuk menjawab permasalahan prospek pengembangan budidaya cabe jawa. Pengambilan data menggunakan metode wawancara dan observasi. Sedangkan analisa data dengan analisis pendapatan, R/C ratio, dan analisis medan kekuatan (FFA). Hasil penelitian menunjukkan bahwa budidaya cabe jawa memiliki pendapatan yang menguntungkan karena penerimaan lebih besar dibandingkan dengan total biaya yang dikeluarkan, biaya budidaya cabe jawa tergolong efisien karena memiliki nilai R/C ratio lebih dari satu. Prospek pengembangan budidaya cabe jawa tergolong baik dikarenakan total nilai faktor pendorong lebih besar dibandingkan faktor penghambat, sehingga budidaya cabe jawa baik untuk dilanjutkan.This study aims to analyse the income of farmers on the cultivation, analyse the efficiency of the cost, and analyse the prospects for the development of Javanese chilli cultivation in Bagorejo Village. The research location was determined by using the purposive method, namely in Bagorejo Village, Gumukmas Subdistrict, Jember Regency. The research used the descriptive and analytic method. The sampling method used total sampling to answer income problems and cost efficiencies, while purposive sampling was to answer the issue of the development prospects of Javanese chilli cultivation. The analysis used revenue analysis, R/C ratio, and force field analysis (FFA). The results of the research showed that: Javanese chilli cultivation had a favourable income because the revenue was higher than the total cost of cultivation. The total cost of Javanese chilli cultivation was efficient because it had an R/C ratio of more than one. The development prospects of Java chilli cultivation was good because the total value of the driving factors was higher than the inhibiting factors of Javanese chilli cultivation, so it was good to be developed.
METAL CONTAMINATION OF THREE COMMERCIALLY FISH SPECIES COLLECTED FROM ACEH (INDONESIA) AND PENANG (MALAYSIA) Sofia, Sofia
Jurnal Kedokteran Hewan Vol 3, No 2 (2009): J. Ked. Hewan
Publisher : Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v3i2.9787

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Concentrations of lead (Pb), cadmium (Cd), and copper (Cu) were determined in muscle and liver tissue in the three commercially fish species, the Indian mackerel (Rastrellinger kanagurta), the tuna (Euthynnus affinis), and the tripletail (Lobotes surinamensis) collected from Aceh (Indonesia) and Penang (Malaysia). In this study, metal concentrations were found highest in the liver tissue compared to the muscle for all fish species (P<0.05). Concentrations ofmetals in the liver were in the range of 0.05 to 0.4 0g/g dry wt for Pb, from 0.13 to 0.67 0g/g dry wt. for Cd, and 1.17 to 3.54 0g/g dry wt. for Cu. While in the muscle, Pb content were in the range of 0.02 to 0.14 0g/g dry wt.; Cd at below 0.12 0g/g dry wt.; and Cu at below 0.54 0g/g dry wt. On the average, among locations, Pb, Cd, and Cu contamination were found significantly higher (P<0.05) in samples collected from Aceh (Indonesia). However, levels of metals in the fish studied were not exceeded the guideline values for food as recommended by Ministry of Agriculture, Fisheries, and Food, UK and the Ministry of Health Malaysia.
Hubungan Lama Memulung Dan Penggunaan Alat Pelindung Diri Dengan Kejadian Penyakit Di Tempat Pembuangan Akhir Sampah sofia, sofia; Kartini, Kartini
AcTion: Aceh Nutrition Journal Vol 1, No 1 (2016): Volume 1 No 1 Tahun 2016
Publisher : Jurusan Gizi Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (168.388 KB) | DOI: 10.30867/action.v1i1.8

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Angka kesakitan pada pemulung tinggi, namun jarang terdeteksi dan tidak ada laporan dari pemulung karena rendahnya kemampuan terhadap akses pelayanan kesehatan. Penelitian ini bertujuan untuk mengetahui hubungan lama memulung dan penggunaan alat pelindung diri terhadap kejadian penyakit pada pemulung.Jenis penelitian bersifat deskriptif analitik dengan desain crossectional menggunakan uji Chi-Square. Sampel dalam penelitian ini seluruh pemulung yang terdata di TPA Gampoeng Jawa Kota Banda Aceh sebanyak 57 orang. Hasil penelitian menunjukkan ada hubungan lama bekerja sebagai pemulung dengan kejadian penyakit pada pemulung di TPA Gampoeng Jawa Kota Banda Aceh dengan nilai p = 0,02. Tidak ada hubungan antara penggunaan APD oleh pemulung dengan kejadian penyakit pada pemulung di TPA Gampoeng Jawa Kota Banda Aceh dengan nilai p = 0,77.Perlu adanya pembinaan terhadap pemulung dari pihak terkait untuk menjaga dan meningkatkan personal higyene pemulung dan membiasakan untuk pemeriksaan kesehatan secara rutin.
Faktor Risiko Lingkungan dengan Kejadian ISPA pada Balita Di Wilayah Kerja Puskesmas Ingin Jaya Kabupaten Aceh Besar Sofia, Sofia
AcTion: Aceh Nutrition Journal Vol 2, No 1 (2017): AcTion Vol 2 No 1 Tahun 2017
Publisher : Jurusan Gizi Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (555.724 KB) | DOI: 10.30867/action.v2i1.35

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Acute Respiratory Infection (ARI) is still one public health problem that is important to note, because it is an acute illness and can even cause death in infants in developing countries, including Indonesia. In general, there are three the risk factors of ARI namely environmental factors, individual factors of children, and behavioral factors. The aim of research to find out the environmental risk factors with the incidence of  ARI  in Toddlers in Public Health Center of Ingin Jaya, Aceh Besar district. This type of research is an analytic survey with cross-sectional study approach. The sample size is calculated using the formula Lemeshow of 100 respondents, samples were taken randomly. Data analysis using Chi-Square test. The results showed that the level of humidity in the home (p= 0,039), smoking habits of family members in the home (p= 0,001), and the habit of using mosquito coils in the home (p= 0,003) as a risk factor for ISPA to children in Region Public Health Center of Ingin Jaya, Aceh Besar district. Conclusion, risk factor of ARI in the toddler that is a smoking habit, usage habit of mosquito coil and air humidity. Suggestions, the public in order to maintain air quality in the home environment to avoid various transmission of infectious diseases.Keywords: Air humidity, habits, environment, ARIPenyakit Infeksi Saluran Pernafasan Akut (ISPA) masih menjadi salah satu masalah kesehatan masyarakat yang penting untuk diperhatikan, karena merupakan penyakit akut dan bahkan dapat menyebabkan kematian pada balita di berbagai negara berkembang termasuk  Indonesia. Secara umum ada 3 (tiga) faktor risiko terjadinya ISPA yaitu faktor lingkungan, faktor individu anak, serta faktor perilaku. Tujuan penelitian untuk mengetahui faktor risiko lingkungan dengan kejadian ISPA pada Balita di wilayah kerja Puskesmas Ingin Jaya Kabupaten Aceh Besar. Jenis penelitian adalah survey analitik dengan pendekatan Crossectional study. Besarnya sampel dihitung dengan menggunakan rumus lameshow yaitu 100 responden, sampel diambil secara acak sederhana. Analisa data dengan menggunakan uji Chi-Square. Hasil penelitian menunjukkan bahwa tingkat kelembaban udara dalam rumah (p=0,039), kebiasaan merokok anggota keluarga dalam rumah (p=0,001), dan kebiasaan menggunakan obat nyamuk bakar di dalam rumah (p=0,003) sebagai faktor risiko kejadian ISPA pada Balita di wilayah kerja Puskesmas Ingin Jaya Kabupaten Aceh Besar. Kesimpulan, faktor risiko ISPA pada balita yaitu kebiasaan merokok, kebiasaan penggunaan obat nyamuk bakar dan kelembaban udara. Saran, masyarakat agar dapat menjaga kualitas udara dilingkungan rumah agar terhindar dari berbagai penularan penyakit infeksi. Kata kunci: Kelembaban udara, kebiasaan, lingkungan, ISPA
Peran UD. Bersama Sejahtera Terhadap Nelayan Rajungan di Desa Tanjung Kecamatan Pademawu Kabupaten Pamekasan Alviansyah, Riezky; Sofia, Sofia; Widjayanthi, Lenny
Jurnal Ekonomi Pertanian dan Agribisnis Vol 2, No 5 (2018)
Publisher : Department of Agricultural Social Economics, Faculty of Agriculture, Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jepa.2018.002.05.8

Abstract

Penelitian ini bertujuan untuk: (1) mengetahui alasan nelayan menjual rajungan kepada UD. Bersama Sejahtera, (2) mengetahui peran UD. Bersama Sejahtera terhadap nelayan rajungan. Penentuan informan dilakukan secara sengaja (purposive sampling). Pengumpulan data menggunakan tiga metode (wawancara, observasi, dokumentasi) dan dianalisis menggunakan model Miles dan Huberman. Uji keabsahan data menggunakan triangulasi sumber. Hasil penelitian menunjukkan bahwa: (1) terdapat lima alasan nelayan menjual rajungan kepada UD. Bersama Sejahtera, yaitu adanya jaminan pasar, adanya pinjaman modal, adanya pinjaman alat tangkap, adanya jaminan harga, syarat yang tidak ketat terkait dengan kualitas rajungan dan angsuran pinjaman, (2) terdapat tiga peran perusahaan terhadap nelayan rajungan, yaitu sebagai penyedia modal dan alat tangkap, sebagai penyedia pasar dan juga sebagai penyampai informasi terkait harga dan kualitas rajungan