M Nur Salim, M Nur
Laboratorium Patologi, Fakultas Kedokteran Hewan UNSYIAH

Published : 5 Documents
Articles

Found 5 Documents
Search

EFFECTS OF PAPAYA LEAF EXTRACT ADMINISTRATION IN CHICKENS: I. DUODENUM PATHOPHYSIOLOGICAL RESPONSE Kamaruddin, Mufti; Salim, M Nur
Jurnal Sain Veteriner Vol 18, No 1&2 (2000)
Publisher : Fakultas Kedokteran Hewan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (71.575 KB)

Abstract

The pathophysiological effects of papaya leaf extract administration were studied in 20 local-three month-old chickens weighing 577±69.979 g. The chickens were randomly evenly divided into 4 groups. P0 group just orally received one single dose Of 3.0 ml aquadest. The P1 P2 P3 and P4 groups were treated orally with one single dose of 1,5 ml, 2.0ml, 2.5 ml and 3.0 ml papaya leaf extract respectively. The extract was made from 400 g papaya leaves, extracted directly by simple traditional methods. Four days after treatment, the chickens were sacrificed, the duodenum were excised for macroscopic examinations, than fixed in 10% formalin prepared for microscopic examination using paraffin method and routine hematoxylin-eosin staining. The results indicated that pathological duodenum effects occurred in groups P2, P3 and P4. Macroscopically, the duodenum were hyperaemic and haemorrhagic. Microscopically the duodenum of these groups showed erosions of ephitelial mucous cells, hyperaemic and haemorrhagic propia. The P0 and Pt did not show any macroscopic and microscopic changes. It was concluded that one single dose of 3.0 ml aquadest or 1.5 ml of papaya leaf did not cause any pathophysiological effects in duodenum chicken, but a single dose of 2.0 ml, 2.5 ml or 3.0 ml did. The greater the dose the worse the effects.          
EFEK PEMBERIAN MINYAK JELANTAH TERHADAP GAMBARANHISTOPATOLOGIS HATI TIKUS PUTIH (Rattus norvegicus) Aisyah, Siti; Budiman, Hamdani; Florenstina BR. G, Dessy; Aliza, Dwinna; Salim, M Nur; Balqis, Ummu; Armansyah, T.
Jurnal Medika Veterinaria Vol 9, No 1 (2015): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.665 KB) | DOI: 10.21157/j.med.vet..v9i1.2989

Abstract

Penelitian ini bertujuan mempelajari gambaran histopatologi hati tikus putih (Rattus norvegicus) akibat mengonsumsi minyak jelantah.  Duapuluh ekor tikus berumur 3 bulan dengan bobot badan ±250 g dibagi atas 4 kelompok perlakuan dan setiap kelompok terdiri at as 5 ekor. Perlakuan K1 (minyak goreng curah), K2, K3, dan K4 (minyak jelantah 3x, 6x, dan 9x pemakaian). Perlakuan dilakukan selama 60 hari, dan pada hari ke 61 dilakukan eutanasia yang dilanjutkan dengan nekropsi. Hati tikus diambil dan difiksasi dalam larutan buffered neutral formaline 10%untuk diproses sediaan histopatologis dan diwarnai dengan hematoksilin dan eosin (HE). Hasil penelitian menunjukkan bahwa hati berwarna coklat kehitaman, bengkak, dan ditemukan nodul multi fokal dengan konsistensi padat. Secara histopatologi terjadi peningkatan kongesti, degenerasi cloudy swelling, dan nekrosis sel
EFEKTIVITAS SALEP GETAH JARAK PAGAR (Jatropha curcas, Linn) PADA FASE EPITELISASI PENYEMBUHAN LUKA SAYAT MENCIT (Mus musculus) fauzy, fauzy; Salim, M Nur; Nazaruddin, Nazaruddin
JURNAL ILMIAH MAHASISWA VETERINER Vol 1, No 3 (2017): MEI - JULI
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (857.793 KB) | DOI: 10.21157/jim vet..v1i3.3311

Abstract

ABSTRAK                      Penelitian ini bertujuan untuk mengetahui tingkat efektivitas pemberian salep getah jarak pagar 10% (Jatropha curcas, Linn) pada fase epitelisasi penyembuhan luka sayat kulit mencit (Mus muskulus). Penelitian menggunakan rancangan acak lengkap (RAL) dengan tiga kelompok perlakuan dan tiga kali ulangan. Digunakan 9 ekor mencit jantan, dengan berat badan 30-40 gram diadaptasikan selama 7 hari di dalam kandang percobaan dengan pemberian pakan komersil dan minum secara ad libitum. Pembuatan luka sayat pada daerah punggung sepanjang 2 cm sampai subcutan. Setelah perlakuan dilakukan perawatan luka pada pukul 08.00 dan 18.00 WIB. Pada kelompok kontrol (KI) dioleskan vaselin kuning, kelompok perlakuan (KII) dioleskan salep getah jarak pagar 10% dan pada kelompok perlakuan (KIII) dioleskan gentamisin 0,1%. Sampel kulit diambil pada hari ke-8 dan diamati secara histopatolgi. Rata-rata jumlah fibroblas pada K1, K2, dan K3 adalah 80,33±2,52, 435,00±7,00, dan 247,67±4,04. Hasil uji ANAVA menunjukkan ada pengaruh yang sangat nyata (P<0,01) antara KI, KII, dan KIII. Dapat disimpulkan bahwa salep getah jarak pagar 10% memiliki potensi mempercepat fase epitelisasi penyembuhan luka sayat pada kulit mencit. Kata Kunci : Getah jarak pagar, Jatropha curcas, Linn., Luka sayat.
PENGARUH PEMBERIAN EKSTRAK KULIT BATANG JALOH TERHADAP GAMBARAN MIKROSKOPIS GINJAL TIKUS PUTIH (Rattus novergicus) YANG DIINFEKSI (Trypanosoma evansi The Effect of Wilow Bark Ekstract Administration on Microscopic Feature of Male Rats (Rattus novergicus) Kidney Infected with Trypanosoma evansi) Nurdiniyah, Nurdiniyah; Nazaruddin, Nazaruddin; Sugito, Sugito; Salim, M Nur; Fahrimal, Yudha; Aisyah, Siti
Jurnal Medika Veterinaria Vol 9, No 2 (2015): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (480.606 KB) | DOI: 10.21157/j.med.vet..v9i2.3949

Abstract

The aims of this study was to examine the ability of willow bark extract to prevent kidney tissue damage from T. evansi infection. This study used 25 rats which were randomly divided into 5 treatment groups, each groups consisted of 5 rats. Rats in control group (K0) were not infected with T. evansi and without administration of willow bark extract. Group 1 (P1) was infected with 103/0,3 ml of T. evansi without willow bark extract administration. Group 2, 3, and 4 were infected with 103/0.3 ml T. evansi and received willow bark extract at dose of 30, 45, and 60 mg/kg bw, respectively. Willow bark extract were administered for 3 days consecutively. On day 4, the rats were sacrificed using chloroform and the kidneys were collected for histopathological examination. Data were analyzed descriptively. The results showed that the administration of willow bark extract at doses of 30 and 45 mg/kg bw were able to prevent damage of tubule cells and glomerular renal, while the administration of 60 mg/kg bw resulted in kidney damage, indicated by necrosis in tubular glomerular cells. It could be concluded that willow bark extract at doses of 30 and 45 mg/kg bw were effective to prevent tissue damage in kidneys.Key words: kidneys, willow, Trypanosoma evansi
KUALITAS SPERMATOZOA SAPI ACEH HASIL SEXING MENGGUNAKAN METODE ELEKTRIK DENGAN VOLTASE 1,5 VOLT DAN 3,0 VOLT DALAM MEDIA SITRAT KUNING TELUR (Spermatozoa Quality of Aceh Cattle based on Sexing Using Electrical Method by Voltages 1,5 Volt and 3,0 Volt in Yolk Sac Citrate Media) nengsih, nadya septia; Dasrul, Dasrul; Akmal, Muslim; Zainuddin, Zainuddin; Riady, Ginta; Salim, M Nur
JURNAL ILMIAH MAHASISWA VETERINER Vol 3, No 2 (2019): FEBRUARI-APRIL
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (602.055 KB) | DOI: 10.21157/jim vet..v3i2.11202

Abstract

ABSTRAKSalah satu bioteknologi reproduksi yang dapat dimanfaatkan sebagai pemisahan spermatozoa kromosom X dan Y adalah sexing spermatozoa menggunakan metode elektrik. Penelitian ini bertujuan untuk mengetahui pengaruh sexing menggunakan metode elektrik dengan voltase 1,5 volt dan 3,0 volt dalam media sitrat kuning telur terhadap kualitas spermatozoa sapi aceh. Penelitian ini menggunakan rancangan acak lengkap (RAL) dengan pola satu arah terdiri atas tiga  perlakuan dan dianalisis dengan analisis varian (ANAVA). Perlakuaan dalam penelitian ini adalah voltase yang terdiri dari kontrol (P0) 1,5 volt ( P1), dan 3,0 volt (P2). Parameter yang dilihat pada penelitian ini meliputi motilitas, viabilitas, dan abnormalitas. Hasil penelitian menunjukan terjadi penurunan kualitas spermatozoa setelah proses pemisahan menggunakan metode elektrik terdapat perbedaan secara nyata (P<0,05). Sexing spermatozoa  menggunakan metode elektrik yang dialiri arus listrik dengan voltase 3,0 volt terhadap kualitas spermatozoa sapi aceh lebih terjadi penurunan dibanding yang dialiri arus listrik dengan voltase 1,5 volt. Berdasarkan hasil tersebut dapat di simpulkan terdapat perbedaan kualitas soermatozoa sapi aceh hasil sexing menggunakan metode elektrik dengan voltase 1,5 volt dan 3,0 volt dalam media sitrat kuning telur.Kata kunci: kualitas spermatozoa, sapi aceh, sexing metode elektrik ABSTRACT                One of the reproductive biotechnology that can be used as a separation of  X and Y chromosome spermatozoa is sexing spermatozoa using an electric method. The aim of this study was to determine the effect of sexing using electric method by voltages 1,5 volt and 3,0 volt in the yolk sac citrate media against spermatozoa quality of  aceh cattle. This study used a completely randomized design (CRD)  in one-way pattern consisting of three treatments and analyzed by analysis of variance (ANOVA). The treatment in this study was the voltages that consists of controls (P0) 1.5 volts (P1), and 3,0 volts (P2).The observed parameters include motility, viability, and abnormality of sperm. The results showed a decrease in the quality of spermatozoa after sexing uses the electric method there were significant differences (P <0.05). Sexing spermatozoa using an electric method that is electrified with a voltage of 3,0 volts against spermatozoa quality of aceh cattle has decreased more than  the electric current with a voltage of 1.5 volts. Based on the results it can be concluded there are differences inthe quality of spermatozoa sexing uses an electric method by a voltage of 1.5 volts and 3,0 volts in the yolk sac citrate media.Keyword: spermatozoa quality, aceh cattle, sexing electric method