Udin Bahrudin, Udin
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HUBUNGAN ANTARA INTENSITAS AKTIVITAS FISIK DAN KADAR ASAM URAT SERUM PADA POPULASI SINDROM METABOLIK Dayana, Bazilah; Bahrudin, Udin
JURNAL KEDOKTERAN DIPONEGORO Vol 4, No 4 (2015): MEDIA MEDIKA MUDA
Publisher : Jurusan Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (16.628 KB)

Abstract

Background: WHO estimated that the prevalence of metabolic syndrome was occured in 23% of male population and 12% of female population in the world. Hyperuricemia had a strong relationship with each component of metabolic syndrome. Earlier studies reported that physical activity played an important role to prevent hyperuricemia.Aim: To find out the assosiation between intensity of physical activity and serum uric acid levels in metabolic syndrome population.Methods: This study was an observational analytic study with cross-sectional design. This study was conducted in RW X, Padangsari, Banyumanik, Semarang in a population based sample aged over 40. The collected data are subject characteristics, serum uric acid levels, andintensity of physical activity. Global physical activity questionnaire (GPAQ), developed by WHO, was used to determine the intensity of physical activity. The Spearman test and chi- square test were used for the statistical analyses.Results: The data showed that 40,6% of 32 subjects with metabolic syndrome had light physical activity, 25% had moderate physical activity and 34,4% had vigorous physical activity. The examination of serum uric acid levels showed that 40,6 % of them had high serum uric acid levels. The Spearman test showed a moderate degree positive correlation between intensity of physical activity and serum uric acid levels (r=0,491; p=0,004). The chi-square test showed a significant relationship between intensity of physical activity categories and serum uric acid levels categories (p=0,023; prevalence ratio 4,17).Conclusions: There was a positive correlation with a moderate degree between intensity of physical activity and serum uric acid levels in metabolic syndrome population.
Baseline and Post-exercise High-Sensitivity C-Reactive Protein Levels in Endurance Cyclists: The Indonesian North Coast and Tour de Borobudur 2017 Study Azam, Mahalul; Lestari, Susanti; Rahayu, Sri Ratna; Fibriana, Arulita Ika; Setianto, Budhi; Widyastiti, Nyoman Suci; Suhartono, Suhartono; Susanto, Hardhono; Kartasurya, Martha Irene; Bahrudin, Udin; Eijsvogels, Thijs
The Indonesian Biomedical Journal Vol 11, No 1 (2019)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v11i1.560

Abstract

BACKGROUND: Inflammation plays an important role in the atherosclerotic process. High-sensitivity C-reactive-protein (hs-CRP) is commonly used as inflammatory biomarker. It is well known that regular physical activity lowers hs-CRP levels, while prolonged exercise induces hs-CRP elevations. However, the relationship of training and exercise characteristics with hs-CRP levels remains not well elucidated. We evaluated baseline and post-exercise hs-CRP levels and its association with training and exercise characteristics.METHODS: Eighty-eight male endurance cyclists were involved. Demographic data, health condition and training characteristics were collected. Baseline and postexercise blood-samples were collected to determine hsCRP concentrations. A hs-CRP cut-off point of 3 mg/L was used. Blood-cell count and biochemical parameters were measured at baseline. Heart rate (HR) was measured during exercise.RESULTS: Cyclists performed 7.3 hours (interquartilerange (IQR) = 5.4-7.5) of endurance exercise at intensity of 81.8 % (IQR = 74.9-85.8). Cyclists with baseline hsCRP ≥ 3 mg/L reported higher body mass, body mass index (BMI), waist-circumference and total-cholesterol. An increase in hs-CRP was following endurance exercise. Cyclists with any elevation of hs-CRP reported a higher BMI, HR during exercise and exercise intensity. Binary logistic regression analysis showed BMI (OR = 1.24, 95% CI = 1.04-1.48) and cycling distance (OR = 0.22, 95% CI = 0.06-0.76) were associated with post-exercise hs-CRP elevations.CONCLUSION: Body mass, BMI, waist-circumference, total- and HDL-cholesterol are associated with baseline hsCRP, whereas BMI and cycling distance were associated with hs-CRP elevations. These findings suggest that anthropometry parameters and lipid levels attributed to baseline hs-CRP, while anthropometry parameters and cycling intensity attributed to post-exercise hs-CRP elevations.KEYWORDS: C-reactive-protein, exercise, endurancecycling, inflammation, acute-phase-response 
Anthropometric-Parameters and Total-Cholesterol to HDL-Cholesterol Ratio are Better in Long-Distance Cyclists (Indonesia North Coast and Tour de Borobudur 2017 Study) Azam, Mahalul; Rahayu, Sri Ratna; Fibriana, Arulita Ika; Susanto, Hardhono; Kartasurya, Martha Irene; Bahrudin, Udin
Jurnal Kesehatan Masyarakat Vol 14, No 2 (2018): Jurnal KEMAS Vol.14 No.2 : November 2018
Publisher : Jurusan Ilmu Kesehatan Masyarakat Fakultas Ilmu Keolahragaan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (195.651 KB) | DOI: 10.15294/kemas.v14i2.14506

Abstract

Total-Cholesterol (TC) to HDL-Cholesterol (HDL-C) ratio in athletes is well-known to be better than sedentary people. However, information about comparison of TC/HDL-C in different groups of cyclists based on cycling touring characteristics and anthropometry parameters is lacking. This study aimed to compare TC/HDL-C ratio between groups based on the type of tour in cyclists population. Eighty-eight participants were recruited in this cross-sectional study. Mean differences of parameters between groups was analyzed by One-Way Anova and independent t-test, whereas multivariate analyses was conducted by binary logistic-regression. P value <0.05 was considered statistically significant. TC/HDL-C ratio in all groups were less than 4.5. There is no differences of TC-levels (NC240K: 216.6±55.04, TdB140K: 208.1±27.13, TdB100K: 203.1±31.95; p=0.427). But there is significantly different level of HDL-C (NC240K: 68.9±19.09, TdB140K: 52.1±13.9, TdB100K: 53.6±12.45; p=0.0001) and TC/HDL-C ratio (NC240K: 3.3±1.12, TdB140K: 4.2±1.07, TdB100K: 4.0±1.06; p=0.007). Between TC/HDL ratio groups (≥4 or <4), there were differences of weight, BMI, waist-circumference, hip-circumference and type of tour (p<0.05). Finally, BMI and type of tour were the most influential factor. Long-distance cyclists have a synergistic effect of lipid profile and anthropometry measurements, and heavier cycling tour participant, that represent cycling training habits, tend to have lower TC/HDL ratio(< 4).