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Deteksi Cemaran Boraks, Formalin, Analisis Proksimat serta Persepsi Pembeli dan Pedagang Bakso yang Berada di Kota Lhokseumawe Mirzal, Juni; Rinidar, Rinidar; Razali, Razali; Sugito, Sugito; Nurliana, Nurliana
Jurnal Teknologi dan Industri Pertanian Indonesia Vol 8, No 2 (2016): Vol.(8) No.2, October 2016
Publisher : Agricultural Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17969/jtipi.v8i2.6269

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Meatballs are one of the foods that undergo processing and meatballs are very popular with people of various backgrounds and ages, where the meatballs assessed consumer acceptance of the characteristics that suit the tastes of consumers without regard to nutrition and food safety standards. This research aims to detect any contamination of borax and formaldehyde in meatballs circulating in the town of Lhokseumawe, analyze the levels proximate to the meatballs circulating in the town of Lhokseumawe, and to determine the level of consumer knowledge meatballs to formaldehyde and borax as harmful preservatives. The samples are meatball sauce and meatball skewers taken from meatballs traders in the city of Lhokseumawe. Results of research on the meatball sauce sold in the shop found a 12.5% positive samples containing borax, while samples meatball skewers sold in schools is not found contamination borax, formalin as well as in the examination did not reveal any contamination of formaldehyde in the meatball sauce and skewers. The test results of proximate levels meatball soup obtained average values and standard deviations where the protein content of 9.43 ± 1.00, 10.53 ± 4.08 fat content, water content of 65.88 ± 3.51, ash content 2 , 76 ± 0.65 and 11.40 ± carbohydrate content of 3.33 and between levels of education and knowledge of the relationship between education and knowledge meatballs consumers to the dangers of borax and formaldehyde when used in food products (P <0.05). Conclusions 12.5% found gravy meatball stall containing borax, and not found any contamination of formaldehyde in the sauce and meatballs skewers and education levels affect the buyer meatballs knowledge about the dangers of formaldehyde and borax, proximate levels meatballs sold in some gravy meatball stall in the town of Lhokseumawe meet the standard values proximate levels meatballs issued by SNI.
The Potency of Sernai (Wedelia biflora) Leaf Water Extract as Antipyretic Compared to Amino Fenol Derivate and Salicylic Acid on Mice (Mus Musculus) Rinidar, Rinidar; Armansyah, Teuku; Putri, Tesha Aprilya
Jurnal Medika Veterinaria Vol 8, No 2 (2014): J. Med. Vet.
Publisher : UNIVERSITAS SYIAH KUALA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (150.479 KB) | DOI: 10.21157/j.med.vet..v8i2.3358

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The study was conducted to screen the antipyretic activity of aqueous of extract of the leaves of sernai (Wedelia biflora) with split-plot design. Eighteen healthy mice weighing between (20-25 g), aged 2-3 months were divided into six groups of three animals each: negative control group were given distilled water (P0), P1, and P2 as a positive control respectively given salicylic acid 42.25 mg/kg body weight, the amino phenol 25 mg/kg body weight, group P3, P4, and P5 given of sernai leaf aqueous extract at a concentration of 50, 75, and 100% respectively. The initial rectal temperature of each animal was recorded by digital thermometer. The pyrexia was induced by injecting a solution of 12.5% peptone. The difference in temperature was observed every 30 minutes for 3 hours and respective time interval was found out by statistical method. The results showed that the water extract of leaves sernai with various concentrations significantly different (P<0.01) with an observation time. Average temperatures in the P5 mice was significantly different (P<0.05) with P0. P3 and P4 is not significantly different from P0, but P3 and P4 significantly different (P<0.05) with P2 and not significantly different from P1. P5 was not significantly different from the P2 and P1 significantly different. It was concluded that the aqueous extract of leaves sernai potential as an antipyretic in mice and at concentrations of 50 and 75% effective in reducing fever in mice tend equivalent to the amino phenol, while the concentration of 100% with salicylic acid.Key words: amino fenol, antipyretic, salicylic acid, sernai
Analisis Risiko Karakteristik, Sosial Ekonomi, Perilaku dan Kondisi Lingkungan Rumah terhadap Kejadian Malaria Sukiswo, Susy Sriwahyuni; Rinidar, Rinidar; Sugito, Sugito
Jurnal Kesehatan Masyarakat Nasional Vol 9 No. 2 November 2014
Publisher : Faculty of Public Health Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (263.51 KB) | DOI: 10.21109/kesmas.v9i2.511

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Malaria merupakan penyakit menular yang menjadi perhatian global. Kecamatan Arongan Lambalek merupakan daerah rawan malaria di Kabupaten Aceh Barat dengan kategori Medium Incidence Area dengan nilai Annual Parasite Incidence (API) 3,67 per 1000 penduduk masih di atas target API Nasional pada fase eliminasi API kurang dari 1 per 1000 penduduk tahun 2013. Penelitian ini bertujuan menganalisis karakteristik, sosial ekonomi, perilaku, dan kondisi lingkungan rumah yang berpengaruh terhadap kejadian malaria di Kecamatan Arongan Lambalek, Kabupaten Aceh Barat. Jenis penelitian ini adalah observasional analitik dengan pendekatan kasus kontrol dengan metode penarikan sampel yaitu purposive sampling. Jumlah sampel dalam penelitian ini terdiri 33 kasus dan 33 kontrol, kelompok kasus adalah orang yang dinyatakan positif malaria sedangkan kelompok kontrol orang yang dinyatakan negatif berdasarkan pemeriksaan mikroskopis/rapid diagnostic test tahun 2014. Analisis statistik yang digunakan analisis univariat, bivariat (kai kuadrat), dan multivariat (regresi logistik). Hasil analisis bivariat diketahui ada lima variabel yang berpengaruh, yaitu pekerjaan (p = 0,000, OR = 0,05), pengetahuan (p = 0,000; OR = 17,5), sikap (p = 0,001; OR = 7,43), tindakan (p = 0,000; OR = 9,8), dan lingkungan (p = 0,000; OR = 9,0). Berdasarkan hasil analisis multivariat, pengetahuan adalah determinan yang paling berpengaruh (p = 0,006; OR = 12,783, CI 95% = 2,045–79,893). Penyuluhan yang intensif mengenai malaria perlu dilakukan untuk lebih menambah pengetahuan dan informasi masyarakat. The Risk Analysis of Characteristic, Socioeconomics, Behavioral, and Home Environment Conditions toward Malaria IncidenceMalaria is an infectious disease of global concern. The Subdistrict of Arongan Lambalek in West Aceh which belongs to the Medium Incidence Area category was a malaria endemic area with Annual Parasite Incidence (API) 3,67 at 1000 population in 2013. The API was higher than national API on elimination phage less than 1 at 1000 population. The objective of this research was to analyze the characteristic, socioeconomic, behavioral, home environment conditions to determine of malaria incidence in Arongan Lambalek Subdistrict, of West Aceh District. This research was analytic observational case control approach with purposive sampling method. The number of samples in this study comprised 33 cases and 33 controls, the cases are people who tested positive for malaria, while the control group of people who tested negative by examination microscopic/rapid diagnostic test in 2014. The statistical analysis used univariate, bivariate (chi-square), and multivariate (logistic regression). The results of the bivariate analysis are five variables known to affect malaria, they are job (p = 0.000, OR = 0.05), knowledge (p = 0.000; OR = 17.5), attitude (p = 0.001; OR = 7.43 ), action (p = 0.000; OR = 9.8), and the environment (p = 0.000; OR = 9.0). Based on the results of the multivariate analysis (logistic regression) knowledge is the most dominan determinan (p = 0.006; OR = 12.783, 95% CI = 2.045 to 79.893). Intensive counseling regarding malaria is needed, to make people know more knowledge and information about malaria.
Motilitas Ascaridia galli Dewasa dalam Larutan Ekstrak Etanol Biji Palem Putri (Veitchia merrillii) Balqis, Ummu; Darmawi, Darmawi; Maryam, Maryam; Muslina, Muslina; Hamzah, Abdullah; Daud, Razali; Hambal, Muhammad; Rinidar, Rinidar; Harris, Abdul; Muttaqien, Muttaqien; Azhar, Azhar; Eliawardani, Eliawardani
Jurnal Agripet Vol 16, No 1 (2016): Volume 16, N0. 1, April 2016
Publisher : Agricultural Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.142 KB) | DOI: 10.17969/agripet.v16i1.3022

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ABSTRAK. Tujuan penelitian ini untuk mengetahui motilitas Ascaridia galli dewasa dalam ekstrak etanol biji Veitchia merrillii. Ekstrak etanol V. merrillii dianalisis fitokimia. Sebanyak 16 ekor cacing A. galli dewasa dibagi kedalam empat kelompok. Cacing pada kelompok pertama adalah kelompok tanpa perlakuan. Cacing pada kelompok kedua diberi 0,6 mg/ml levamisole. Cacing pada masing-masing kelompok ketiga dan keempat diberi 50 dan 100 mg/ml crude ekstrak biji V. merrillii. Motilitas A. galli ditentukan dalam skor persentase setelah 12, 24, 36 jam dengan menggunakan kriteria: 3 (badan bergerak), 2 (hanya sebagian badan bergerak), 1 (tidak bergerak tetapi masih hidup), 0 (mati). Hasil fitokimia V. merrillii mengandung alkaloids, saponins, tannins, flavonoids, terpenoids. Ekstrak biji V. merrillii dosis 100 mg/ml secara in vitro dapat mempersingkat selama 12 jam waktu motilitas cacing A. galli dewasa. Penelitian ini mengindikasikan potensi anthelmintik berbasis herbal untuk pengendalian A. galli.  (Motility of Ascaridia galli adult worms in vitro in ethanolic extracts of Nuts Veitchia merrillii) ABSTRACT. The purpose of this research was to know the motility of Ascaridia galli adult worms in aqueous ethanolic extracts of nuts Veitchia merrillii. The ethanolic extract of the V. merrillii was analyzed. Amount of sixteen head A. galli adult worms were divided into four groups. The first group, worms were left as un-treated normal controls. The second group, worms were treated with concentrations of 0,6 mg/ml levamisole. The third and fourth group, worms were treated with crude aqueous ethanolic extract of 50 and 100 mg/ml concentrations nuts of the V. merrillii, respectively. Motility of A. galli were determined after 12, 24, 36 hour by mean of persentage scored using the following criteria: 3 (moving whole body), 2 (moving only parts of the body), 1 (immobile but alive), and 0 (died). The result of phytochemical V. merrillii contains alkaloids, saponins, flavonoids, tannins, and terpenoids. V. merrillii nuts extract concentrations of 100 mg/ml in vitro can shorten the time motility A. galli adult worms for 12 hours. The study indicated the potential for developing herbal-based anthelmintics to control A. galli.
PENGARUH PEMBERIAN EKSTRAK DAUN BINAHONG (Anredera cordifolia) TERHADAP PROSES PENYEMBUHAN LUKA INSISI (Vulnus incisivum) PADA MENCIT (Mus musculus) Pebri, Ines Gusti; Rinidar, Rinidar; Amiruddin, Amiruddin
JURNAL ILMIAH MAHASISWA VETERINER Vol 2, No 1 (2017): NOVEMBER - JANUARI
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (552.273 KB) | DOI: 10.21157/jim vet..v2i1.5655

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Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak daun binahong (Anredera cordifolia) terhadap proses penyembuhan luka insisi pada mencit (Mus musculus).Hewan coba yang digunakan mencit sebanyak 12 ekor, berjenis kelamin jantan, berumur 2-3 bulan dan berat badan 20-50 gram. Luka insisi dibuat pada punggung mencit menggunakan scalpel sepanjang 1cm. Penelitian ini menggunakan rancangan acak lengkap (RAL) dengan 4 perlakuan dan 3 ulangan.Perawatan dilakukan 1 kali sehari selama 14 hari yaitu K1 diberi aquades, K2 (ekstrak daun binahong 5%), K3 (ekstrak daun binahong 10%), dan K4 (ekstrak daun binahong 15%).Parameter proses penyembuhan luka yang diamati adalah ukuran luka, kemerahan dan udema, terbentuknya keropeng dan terlepasnya keropeng yang diukur dalam satuan hari. Data hasil pengamatan dianalisis secara deksriptif. Hasil penelitian menunjukkan bahwa dosis 15%  menunjukkan hasil kesembuhan yang lebih cepat pada luka insisi dibandingkan dengan aquades, ekstrak daun binahong 5%, dan 10%. Disimpulkan bahwa pemberian ekstrak daun binahong pada konsentrasi 15% dapat menyembuhkan dan mempercepat proses penyembuhan luka insisi pada mencit dibandingkan dengan konsentrasi 10% dan 5%.This study aims to determine the provision leaves extract Binahong (Anredera cordifolia) towards the wounds healing insision in mice (Mus musculus). This experiment used 12 mice, male, aged 2-3 months old and weight 20-50 grams. Insision was made on the backs of mice using a scalpel as 1 cm long. Completely Randomized Design (CDR) was used in this study with 4 treatment groups and 3 repepetitions. Treatment is done once a day for 14 days which K1 is given aquades, K2 (binahong leaf extract 5%), K3 (binahong leaf extract 10%) and K4 (binahong leaf extract 15%).The parameter of the wounds healing process observed were wound siza, redness and udema, the formation of scabs and the removal of scabs measured in units of days. This analysis is done by using descriptive analysis. The result showed that leaf extract binahong 15%  speed up the healing incision wound mice rather than aquades,leaf extract binahong 5% and 10%. It was concluded that leaf extract binahong 15% speed up the wounds healing incision of mice rather than leaf extract binahong 10% and 5%.
DETEKSI ANTIBODI VIRUS AVIAN INFLUENZA SUBTIPE H5N1 PADA BURUNG MERPATI (Columba livia) (Detection Antibodies of Avian Influenza Virus Subtype H5N1 on Pigeon (Columba livia) ) Erina, Erina; Harahap, Abdullah Azmi; Abrar, Mahdi; Helmi, Teuku Zahrial; Salim, Muhammad Nur; Rinidar, Rinidar
JURNAL ILMIAH MAHASISWA VETERINER Vol 3, No 1 (2018): NOVEMBER-JANUARI
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (703.824 KB) | DOI: 10.21157/jim vet..v3i1.9903

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 Penelitian Penelitian ini bertujuan untuk mendeteksi antibodi spesifik terhadap virus Avian Influenza subtipe H5N1 pada burung merpati. Penelitian ini dilaksanakan di Laboratorium Mikrobiologi Fakultas Kedokteran Hewan Universitas Syiah Kuala, Darussalam Banda Aceh. Penelitian ini menggunakan sampel serum darah burung merpati sebanyak 25 sampel. Pengambilan sampel darah merpati menggunakan spuit 3cc melalui vena brachialis di kiri ataupun kanan bawah sayap merpati, kemudian didiamkan selama 6-10 jam dengan posisi miring. Darah dibiarkan  hingga terpisah dari serum, kemudian serum dikoleksi dan disimpan di suhu -20°C. Serum sebelum digunakan  terlebih dahulu di simpan pada suhu 56°C selama 30 menit untuk menginaktifasi komplemen. Pemeriksaan sampel tersebut menggunakan uji Hemaglutinasi Inhibisi (HI). Hasil dari penelitian ini menunjukkan bahwa dari 25 sampel serum yang diperiksa, 22 sampel (88%) positif mengandung antibodi terhadap virus Avian Influenza subtipe H5N1 namun 3 sampel (12%) tidak mengandung titer antibodi terhadap virus Avian Influenza subtipe H5N1. Dapat disimpulkan bahwa merpati tersebut pernah terpapar oleh virus Avian influenza subtipe H5N1. Kata kunci: merpati, avian influenza, antibodi, uji hiABSTRACT This study aims to detect specific antibodies of  Avian Influenza virus H5N1 subtype on pigeons. This study was carried out at the Microbiology Laboratory, Faculty of Veterinary Medicine, Syiah Kuala University, Banda Aceh. This study used 25 pigeon blood serum samples. Pigeons blood sampling using 3cc syringe through the brachial vein on the left or right under the pigeons wings, then allowed to stand for 6-10 hours with a sloping position. The blood is left frozen so that the serum is separated, then the serum is collected and stored at -20 ° C. Serum samples of pigeons before being used inactivated first at 56 ° C temperature for 30 minutes. Examination of these samples uses the Hemaglutination Inhibition (HI) test. The results of this study showed that the 25 examined serum samples, 22 positive samples contained antibody titers of the H5N1 subtype Avian Influenza virus and only 3 negative samples contained antibody titers against the Avian Influenza virus subtype H5N1. The presence of antibodies formed in the pigeons serum showed that the pigeon had been exposed to the H5N1 subtype Avian Influenza virus. Keywords: pigeon, avian influenza, antibody, hi test 
PENGARUH PEMBERIAN EKSTRAK KULIT BATANG JALOH (Salix tetrasperma Roxb) DAN SERBUK DAUN SINGKONG (Manihot esculenta Crantz) TERHADAP PERTAMBAHAN BOBOT BADAN AYAM BROILER (Effect of Willow (Salix tetrasperma Roxb) Bark Extract and Cassava (Manihot esculenta Crantz) Leaf Powder Supplementation on Weight Gain of Broiler Chickens) Harfinda, Hanum; Rinidar, Rinidar; Armansyah, T.; Sugito, Sugito; Sabri, Mustafa; Winaruddin, Winaruddin
Jurnal Medika Veterinaria Vol 10, No 1 (2016): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (228.132 KB) | DOI: 10.21157/j.med.vet..v10i1.4039

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This study’s purpose is to determine the effect of supplementation of willow bark extract (1000 mg/L) in drinking water and 15% cassava leaf powder in feed on broiler weight gain. This study was designed using completely randomized design (CRD) in which 20 broiler chickens were divided into four treatment groups with five broiler per each treatment. Control group (P0) was only given commercial feed, P1 (commercial feed + cassava leaf powder), P2 (commercial feed + willow bark extract), and P3 (commercial feed + cassava leaf powder and willow bark extract). Data were analyzed using analysis of variance and followed by Duncan test. The results showed that P2 significantly different (P<0.01) compare to P0 and P3, and different (P>0.05) from P1. Group P1 was different (P<0.05) from group P3, but P3 showed no significant different (P>0.05) to P0 on weight gain. whereas feed intake was similar among treatments, however food conversion was differ among treatments. In conclusion, combination of willow bark extract and cassava leaf powder could not increase broiler chickens weight gain.
PENGARUH PENAMBAHAN EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus polyrhizus) DALAM MEDIA SITRAT KUNING TELUR TERHADAP DAYA TAHAN HIDUP SPERMATOZOA SAPI ACEH YANG DISIMPAN PADA SUHU 4℃ (The Effect of Adding Peels Red Dragon Fruit Extract (Hylocereus polyrhizus) into Citrate-Yolk Medium to the Survival of the Aceh Cattle Spermatozoa Stored at Temperature 4℃) Wahyuni, Sonya Tri; dasrul, dasrul; hamdan, hamdan; melia, juli; rinidar, rinidar; siregar, tongku N
JURNAL ILMIAH MAHASISWA VETERINER Vol 2, No 2 (2018): FEBRUARI - APRIL
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (138.111 KB) | DOI: 10.21157/jim vet..v2i2.6888

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Penelitian ini bertujuan mengetahui pengaruh penambahan ekstrak kulit buah naga merah dalam media sitrat kuning telur terhadap daya tahan hidup spermatozoa sapi aceh setelah pendinginan. Semen ditampung dari 1 ekor pejantan umur 3 tahun sehat, menggunakan vagina buatan. Semen yang berkualitas baik dibagi ke dalam 5 kelompok perlakuan penambahan ekstrak kulit buah naga merah; 0,00 g/100 ml (P0); 0,2 g/100 ml (P1); 0,4 g/100 ml (P2); 0,6 g/100 ml (P3); dan 0,8 g/100 ml (P4) dalam media sitrat kuning telur dan disimpan dalam suhu 4. Pengamatan daya tahan hidup spermatozoa dilakukan setiap hari selama 5 hari. Data yang diperoleh dianalisa dengan analysis of varian(ANOVA) pola satu arah yang dilanjutkan dengan uji berganda Duncan. Hasil pengamatan daya tahan hidup spermatozoa setelah pendinginan pada perlakuan P0; P1; P2; P3; dan P4 secara berturut-turut 3,8; 4,6; 3,6; 1,0; dan 0,0 hari. Hasil penelitian ini menunjukkan bahwa penambahan ekstrak kulit buah naga merah dalam media sitrat kuning telur berpengaruh secara nyata (P<0,05) terhadap daya tahan hidup spermatozoa. Penambahan ekstrak kulit buah naga merah 0,2 g/100 ml dalam media sitrat kuning telur menghasilkan daya tahan hidup spermatozoa sapi aceh lebih baik selama penyimpanan pada suhu 4. (This study aims to determine the effect of peels red dragon fruit extract addition into citrate-yolk medium on viability of aceh cattle sperm after cooling. Semen was collected from 1 healthy male aged 3 years, using artificial vagina. Good quality semen was divided into 5 groups; addition of peels red dragon fruit extract 0.0 g/100 ml (P0); 0.2 g/100 ml (P1); 0.4 g/100 ml (P2); 0.6 g/100 ml (P3); and 0.8 g/100 ml (P4) into citrate-yolk medium, and stored in a temperature of 4. Observation of sperm viability were done every day up to day 5. The data obtained was analyzed with the one-way analysis of variance (ANOVA), followed by multiple test Duncan. Results show sperm viability after cooling in the groups P0; P1; P2; P3; and P4 respectively was 3.8 days, 3.6 days, 4.6 days, 1.0 day, and 0.0 day. The results show that the addition of peels red dragon fruit extract in citrate-yolk medium affects significantly (P<0.05) sperm viability. The addition 0.2 g/100 ml peels red dragon fruit extract into citrate-yolk medium during storage in a temperature of 4 results greater sperm viability.)
FRAKSI METANOL DAUN SERNAI (Wedelia biflora) SEBAGAI ANALGESIK PADA MENCIT PUTIH (Mus musculus) YANG DIINDUKSI ASAM ASETAT GLASIAL Rinidar, Rinidar; TR, T Armansyah; Putra, Irsyad Arfi
JURNAL ILMIAH MAHASISWA VETERINER Vol 1, No 1 (2017): NOVEMBER - JANUARI
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (307.471 KB) | DOI: 10.21157/jim vet..v1i1.2235

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Penelitian ini bertujuan mengetahui potensi fraksi metanol daun sernai sebagai analgesik pada mencit putih (Mus musculus) yang diinduksi asam asetat glasial. Hewan coba dalam penelitian ini adalah 25 ekor mencit. Sampel penelitian yang digunakan adalah tumbuhan sernai yang berumur lebih dari 1 tahun setelah ditanam dan panjang tanaman telah lebih dari 0,3 meter. Pembuatan ekstrak metanol dilakukan secara maserasi dari serbuk daun sernai. Pembuatan fraksi metanol dilakukan dengan melarutkan ekstrak kental metanol menggunakan pelarut heksan. Penelitian ini menggunakan rancangan acak lengkap (RAL) pola split plot terdiri atas 5 perlakuan dan 5 ulangan. Kontrol negatif diberi akuades (P0), kontrol positif diberi ibuprofen (P1), dan kelompok (P2, P3, P4) diberi fraksi metanol daun sernai dengan dosis 30, 45 dan 60 mg/kg bb. Uji efek analgesik dilakukan dengan metode abdominal writhing. Data dianalisis dengan analisis varian dan dilanjutkan dengan uji Duncan. Hasil penelitian menunjukkan bahwa fraksi metanol daun sernai memiliki pengaruh yang nyata (P<0,05) terhadap penurunan geliat mencit. Uji lanjut Duncan kelompok P2 dan P3 tidak berbeda nyata (P>0,05) dengan kelompok P1, berbeda nyata (P<0,05) dengan P0. Kelompok P4 berbeda nyata (P<0,05) dibandingkan kelompok P0. Disimpulkan bahwa fraksi metanol daun sernai memiliki potensi sebagai analgesik.Kata kunci: ibuprofen, analgesik, daun sernai.The aim of this study was to understand the potential of methanol fraction of sernai leaves as an analgesic in mice (Mus musculus) experimentally induced by glacial acetic acid. Total of samples were 25 mice. Sample of research was sernai 1 year old and length more than 0.3 meters. Methanol extract made by maceration of sernai powder and dissolved using hexane. This study used a complete randomized design (CRD) with split plot pattern consist of 5 groups and 5 repetitions. Group (P0) as negative control was given aquadest, group (P1) as positive control was given ibuprofen, and group (P2, P3, P4) were given metanol fraction of beach sunflower leaves of 30 mg/kg bw, 45 mg/kg bw and 60 mg/kg bw doses. The analgesic effect used abdominal writhing method. The data was analyzed by analysis of variant and Duncan. The result of the experiment showed that methanol fraction of beach sunflower leaves had significant effect (P<0,05) to reduce pain streching movements in mice. Duncan analysis showed that group P2 and P3 was not significantly different (P>0,05) with group P1 but significantly different (P<0,05) to group P0. Group P4 was significantly different (P<0,05) with group P0. So that methanol fraction of beach sunflower leaves has potential as analgesic.Keyword: ibuprofen, analgesic, beach sunflower leaves.
PENGARUH EKSTRAK ETANOL DAUN JAMBLANG (Syzygium cumini (L.) SKEELS) TERHADAPT GLUKOSA DARAH PADA TIKUS PUTIH (Rattus norvegicus) DIABETES MELLITUS YANG DIINDUKSI STREPTOZOTOSIN Mustika, Delvy Yuana; NA, Zuhrawaty; Harris, Abdul; Rinidar, Rinidar; Asmilia, Nuzul; Hasan, Muhammad
JURNAL ILMIAH MAHASISWA VETERINER Vol 1, No 4 (2017): AGUSTUS-OKTOBER
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (28.876 KB) | DOI: 10.21157/jim vet..v1i4.4349

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol daun jamblang terhadap kadar glukosa darah pada tikus putih diabetes mellitus yang diinduksi Streptozotosin (STZ). Hewan coba yang digunakan adalah 15 ekor tikus putih jantan dengan berat badan 200-250g. Tikus secara acak dibagi menjadi 5 kelompok perlakuan masing-masing terdiri dari 3 ekor. Kelompok control negatif  (KN) tidak diinjeksi STZ dan tidak diberi Ekstrak Etanol Daun Jamblang (EEDJ), kelompok control positif (KP) diinjeksi STZ 40 mg/kg BB dan tidak diberi EEDJ, kelompok P1, P2, dan P3 diinjeksi STZ 40 mg/kg BB dan diberi EEDJ dengan dosis masing-masing 100 mg/kg BB, 150 mg/kg BB dan 200 mg/kg BB. Pemberian EEDJ diberikan secara oral selama 14 hari. Penelitian ini menggunakan metode Rancangan Acak Lengkap pola searah. Hasil analisis varian menunjukkan bahwa perlakuan pemberian EEDJ berpengaruh sangat nyata (P<0,01) terhadap penurunan kadar glukosa darah tikus. Rata-rata kadar glukosa darah tikus kelompok KN (110,33±8,38 mg/dL), KP (448,00±40,33 mg/dL), P1 (100,00±8,34 mg/dL), P2 (103,33±5,68 mg/dL) dan P3 (92,00±6,08 mg/dL). Dari hasil penelitian dapat disimpulkan bahwa pemberian EEDJ dapat menurunkan kadar glukosa darah tikus putih jantan diabetes mellitus yang diinduksi STZ. Dosis EEDJ yang efektif untuk menurunkan kadar glukosa darah adalah 200 mg/kg BB.
Co-Authors Abdul Harris Abdullah Hamzah, Abdullah Al Azhar Amiruddin Amiruddin Azhar Azhar Br. Hasibuan, Siti Prawitasari Darmawi Darmawi Dasrul Dasrul Dian Masyitha Eliawardani Eliawardani, Eliawardani Elsavira, Radhika Erdiansyah Rahmi Erina Erina Erwin Erwin Fakhrurrazi Fakhrurrazi Gholib Gholib, Gholib Hadi, Devy Kartika Hamdan Hamdan Hamny Hamny Harahap, Abdullah Azmi Harfinda, Hanum Heryanita, Yola Ira Susanti Juli Melia M Hasan M. Aman Yaman M. Hasan M. Jalaluddin, M. Maghfirah, Siti Mahdi Abrar Mariana Mariana Maryam Maryam Mauliza, Dewi Mirzal, Juni Muhammad Hambal Muhammad Hasan Muhammad Iqbal Muhammad Isa Muhammad Jalaluddin, Muhammad Muslina Muslina, Muslina Mustafa Sabri Mustika, Delvy Yuana Muthmainnah A, Nafsul Muttaqien Muttaqien, Muttaqien NA, Zuhrawaty Nasrun, Diana Noviandi, Idham NURLIANA NURLIANA Nuzul Asmilia Pebri, Ines Gusti Putra, Irsyad Arfi Rahmatia, Annisa Rizka Rasmaidar Rasmaidar Razali Daud Razali Razali Riandi, Lian Varis Rizki Aulia Roslizawaty Roslizawaty, Roslizawaty Rosmaidar Rosmaidar, Rosmaidar Rusli Rusli S, Susy Sriwahyuni Safika, Safika Salim, Muhammad Nur Sayuthi, Arman Siti Hajar Sofia Sofia, Sofia Sri Wahyuni Sugito Sugito Susy Sriwahyuni Sukiswo, Susy Sriwahyuni Syahputra, Yandi T Armansyah, T T. Armansyah T. Armansyah TR, T. Armansyah T. Fadrial Karmil Tesha Aprilya Putri, Tesha Aprilya Teuku Armansyah Teuku Zahrial Helmi Tongku N Siregar TR, T Armansyah Ummu Balqis Vara Tassa Sutari, Vara Tassa Wahyuni, Sonya Tri Wenny Novita Sari Winaruddin Winaruddin Yudha Fahrimal Zulkarnaini Zulkarnaini Zuraidawati Zuraidawati, Zuraidawati