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Perbedaan Tekanan Darah Sebelum dan Sesudah Paparan Heat Stress pada Pekerja Perusahaan Industri Alumunium Yogyakarta

JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 3, No 8, (2011)
Publisher : Faculty of Medicine

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Abstract

One source of danger in workplace is heat stress. Heat stress can cause changes in the cardiovascular system. The workload of heart will increase to regulate body temperature when body temperature rises due to exposure to heatstress. The objectives of this study were to find out the differences of blood pressure before and after exposure to heat stress on workers of Industrial Company Aluminium Yogyakarta. This study uses observational analytic methodwith cross sectional approach. The sample in this study that meets inclusion criteria is 25 people from two Industrial company Aluminium Yogyakarta (TS and ED). Data is collected by interview using a questionnaire to determine thecharacteristics of the respondents and measurements of heat stress, blood pressure in supine and standing position and axillary temperature. The statistical test performed using Wilcoxon match pair test with computer program. The average of heat stress in production section of Industrial Company TS Aluminium is 31.7 °C and ED Alumunium 32.6 °C. The average body temperature increased by 0.8 °C after exposure to heat stress (P <0,001). Systolic and diastolic blood pressure in supine and standing position decreased significantly after exposure to heat stress. Heat stress decreased systolic in supine (P<0,001) and standing (P<0.001) likewise diastolic in supine (P<0,001) and standing (P<0,001). Difference in systolic and diastolic blood pressure when changing body position prior heat stress compared to after heat stress no significant changes. Difference in systolic (P = 0.093) and difference in diastolic (P = 0.379). Based on this research, it can be concluded that there is significant differences in blood pressure before and after exposure to heat stress on workers of Industrial Company Aluminium Yogyakarta.

Perbedaan Kadar Resistin Pada Obes Dengan Resistensi Insulin Dan Obes Tanpa Resistensi Insulin

JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol1, No 1, (2009)
Publisher : Faculty of Medicine

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Abstract

Resistin is an adipocytokine that secreted from adipose tissue, resistin level serum increased in obese patients. Resistin has important biological activity on glucose and lipid metabolism, and can affect insulin resistance. Previous study suggested that high level resistin can induce insulin resistance and has contribution to impaired insulin sensitivity. The Objective of this study is to know differences of resistin level in obese with insulin resistance and obese without insulin resistance. This is a cross sectional study  with obesity patients recruited from General Check Up  and Endorinology  outpatients clinic Sardjito General Hospital Yogyakarta. Obese patients are subjects with body mass index (BMI) ≥ 25 kg/m2. Insulin resistance was assessed using HOMA-IR (homeostasis model assessment insulin resistance), formula calculated from fasting insulin and glucose levels.  Resistin  was measured with ELISA technique. Differences of obese with insulin resistance and obese without insulin resistance analyze using  Mann Whitney U test.   There was 48 subjects  analyzed in this study, 24 obese patients with insulin resistance and 24 obese patients without insulin resistance. Mean of resistin level was higher in obese subject with insulin resistance than without insulin resistance, but there was no significant (27,65±14,44 ng/ml vs 23,99±12,45 ng/ml, p= 0,37). From this research, it can be concluded that Resistin level in obese with insulin resistance higher than obese without insulin resistance, but no significant.Keywords: Resistin-Insulin Resistance-obese

Hubungan Kadar Glukosa Darah dengan Kulitas Hidup pada Pasien Diabetes Melitus Tipe II di RSUD Sleman Yogyakarta

JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 2, No 6, (2010)
Publisher : Faculty of Medicine

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Abstract

Diabetes mellitus is a chronic disease with blood glucose levels higher than normal. Prevalence of diabetes mellitus is increasing, especially diabetes mellitus type 2 caused by various factors like lifestyle changed that affect the quality of health care. The quality of health-related quality of life. The aim this study to investigated the relationship between blood glucose level with the quality of life in patients with diabetes mellitus type 2 in Sleman district hospital. The study is descriptive quantitative research with cross sectional analytic. Data taken from questionnaires of quality of life and the medical records patients with diabetes mellitus type 2 in Sleman district hospital, Yogyakarta. Analityc methods to shown association between blood glucose level with the quality of life in patients with diabetes mellitus type 2 used Chi-Square Test. The sample in this study were 64 cases of diabetes mellitus type 2 with inclusion criteria. Diabetes mellitus type 2 with high blood glucose level and lower quality of life as much as 41 cases. For patients diabetes mellitus type 2 with high blood glucose levels and high quality of life for as much as 4 cases. While people with diabetes mellitus type 2 with low blood glucose levels and lower quality of life as much as 5 cases. Patients of diabetes mellitus type 2 with blood glucose levels low and high quality of life as much as 14 cases. There is a significant Association between blood glucose level with the quality of life in patients with diabetes mellitus type 2 (p=0,000). This study concluded that there was a a significant Association between blood glucose level with the quality of life in patients with diabetes mellitus type 2,

HUBUNGAN ANTARA KADAR ASAM URAT SERUM DENGAN TINGKAT KEPARAHAN PENYAKIT JANTUNG KORONER DI RSU PKU MUHAMMADIYAH YOGYAKARTA

JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 6, No 2, (2014)
Publisher : Faculty of Medicine

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Abstract

Latar Belakang Penyakit jantung koroner (PJK) dikenal sebagai penyebab utama kematian. Faktor risiko yang jarang disebutkan yaitu, tingginya kadar asam urat serum. Hubungan yang pasti antara keduanya sebenarnya masih kontroversial dan masih terus diteliti kebenarannya. Beberapa penelitian menyebutkan bahwa asam urat berkorelasi dengan perburukan PJK. Tujuan Tujuan penelitian ini adalah untuk mengetahui hubungan antara kadar asam urat serum dengan tingkat keparahan penyakit jantung koroner di RSU PKU Muhammadiyah Yogyakarta. Metode Desain penelitian adalah cross sectional. Data diambil dengan metode consecutive sampling dari catatan rekam medis pasien PJK periode 1 Januari 2010 - 31 Desember 2012. Subyek penelitian adalah (1) Pasien didiagnosis dokter menderita PJK dengan kriteria PERKI, (2) Kelengkapan rekam medis meliputi nama, umur, jenis kelamin, kadar asam urat, dan tingkat keparahan PJK (kejadian komplikasi). Kadar asam urat yang dipakai adalah kadar asam urat yang pertama kali diukur saat masuk rumah sakit. Tingkat keparahan PJK dibagi kedalam PJK fatal dan non-fatal berdasarkan ada tidaknya komplikasi dan ancaman kematian. Analisis data dilakukan dengan uji Chi Square. Hasil Berdasarkan hasil analisis data dengan menggunakan uji Chi Square dari total 68 sampel penelitian (n1=n2=34) diperoleh nilai p = 0,28 dengan Rasio Prevalence = 1,643 (95% CI = 1,033 - 2,613). Kesimpulan Terdapat hubungan antara kadar asam urat serum dengan tingkat keparahan penyakit jantung koroner di RSU PKU Muhammadiyah Yogyakarta. Kata Kunci: Asam urat, tingkat keparahan, penyakit jantung koroner