Articles

UJI AKTIVITAS ANTIHIPERKOLESTEROLEMIA EKSTRAK AIR BUAH BELIMBING WULUH (Averrhoa bilimbi Linn.) PADA PEMODELAN TIKUS JANTAN GALUR WISTAR HIPERKOLESTEROLEMIA Azhari, Bary; Luliana, Sri; Robiyanto, Robiyanto
Majalah Obat Tradisional Vol 22, No 1 (2017)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/tradmedj.24319

Abstract

Buah belimbing wuluh (Averrhoa bilimbi Linn.) memiliki aktivitas antihiperkolesterolemia. Penelitian ini bertujuan untuk mengetahui potensi antihiperkolesterolemia, menentukan dosis optimal dan mengetahui pengaruh pemberian ekstrak air buah belimbing wuluh (Averrhoa bilimbi Linn) terhadap indeks organ tikus. Hewan uji yang digunakan adalah tikus jantan galur Wistar. Hewan uji dibagi menjadi 4 kelompok, yaitu kontrol normal, kontrol negatif, kontrol positif (Simvastatin 0,18 mg/kgbb), dan ekstrak air buah belimbing wuluh dosis 63 mg/kgbb. Parameter yang dilihat adalah, kadar kolesterol total diukur dengan metode CHOD-PAP, berat badan tikus selama 50 hari, dan indeks organ yang selanjutnya diuji secara statistik (One way ANOVA). Pada parameter penurunan kadar kolesterol darah tikus antara kelompok positif dengan kelompok ekstrak air buah belimbing wuluh dosis 63 mg/kgbb tidak mengalami perbedaan bermakna secara statistik. Sedangkan, kelompok ekstrak air buah belimbing wuluh dosis 63 mg/kgbb dan kontrol negatif mengalami perbedaan bermakna (p<0,05). Simpulan, ekstrak air buah belimbing wuluh dosis 63 mg/kgbb memiliki efek antihiperkolesterolemia yang dilihat dari penurunan kadar kolesterol total dari hari ke-30 dan hari ke-50,serta secara statistik berbeda bermakna dengan kontrol negatif,  dan dapat mempengaruhi indeks organ limpa dan pankreas namun tidak mempengaruhi indeks organ ginjal, hati, jantung, dan paru-paru.
PEMANFAATAN PELEPAH SAWIT SEBAGAI SUMBER HIJAUAN DALAM RANSUM SAPI POTONG Nurhaita, Nurhaita; Ruswendi, Ruswendi; Wismalinda, Wismalinda; Robiyanto, Robiyanto
Pastura : Jurnal Ilmu Tumbuhan Pakan Ternak Vol 4 No 1
Publisher : Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/Pastura.2014.v04.i01.p09

Abstract

Tujuan penelitian adalah untuk mengevaluasi pengaruh pemanfaatan pelepah sawit sebagai sumber hijauan dalam ransum sapi potong. Pelepah sawit yang telah diamoniasi digunakan sebagai pengganti 100% rumput dengan suplementasi nutrient precursor mikroba rumen yaitu daun ubi kayu, mineral Sulfur dan Fosfor Penelitian menggunakan Rancangan Acak Kelompok dengan 5 ransum perlakuan dan 4 kelompok sapi sebagai ulangan. Sebagai perlakuan adalah ransum A= yaitu rumput lapangan, sebagai kontrol, B = pelepah sawit amoniasi , C= pelepah sawit amoniasi + suplementasi 5% daun ubi kayu, D = pelepah sawit amoniasi + suplementasi 0,4% mineral S dan 0,27% mineral P, dan E= pelepah sawit amoniasi + suplementasi mineral S,P dan daun ubi kayu. Parameter yang diukur adalah 1) Konsumsi bahan kering, dan 2) Pertambahan bobot badan. Hasil penelitian menunjukkan bahwa perlakuan tidak berpengaruh terhadap konsumsi bahan kering, namun berpengaruh terhadap pertambahan bobot badan. Pertambahan bobot badan terendah ditemukan pada ransum pelepah sawit amoniasi tanpa suplementasi (perlakuan B) namun pertambahan bobot badan pada ransum perlakuan C, D dan E hampir sama dengan perlakuan A yang menggunakan rumput. Dari penelitian ini dapat disimpulkan bahwa penggunaan pelepah sawit amoniasi dengan suplementasi daun ubi kayu dan mineral S, dan P dapat menggantikan 100% rumput dalam ransum ternak sapi dan memberikan performan yang sama dengan ransum kontrol (rumput)
The Influence of Exchange Rate, World Oil Price, and BI Rate on Airline Companie’s Return in Indonesian Stock Market Stefan, Yonatan Alvin; Robiyanto, Robiyanto
International Journal of Social Science and Business Vol 3, No 3 (2019)
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (506.549 KB) | DOI: 10.23887/ijssb.v3i3.21059

Abstract

In an effort to support the economic growth of Indonesia, an infrastructure development is carried out to achieve the national development. It brings positive influences on transportation companies in Indonesia. Many companies list their shares to Indonesia Stock Exchange, including PT. Garuda Indonesia (Persero) Tbk (IDX code: GIAA) and PT. AirAsia Indonesia Tbk (IDX code: CMPP), aiming to have additional capital sources. The two companies can be such a reference for investors to make investments, but they still need to consider the macro factors attached. This study examines the influende of exchange rate, world oil price, and Bank Indonesia (BI) rates on the GIAA and CMPP stock returns. The analysis technique used was Generalize Autoregressive Conditional Heteroscedasticity (GARCH) and daily data starting from their IPO to February 28th, 2019. The results showed that the exchange rate negatively affected the GIAA and CMPP stock returns, while the world oil prices only negatively affected the CMPP stock return, and the BI rates only negatively affected the GIAA stock return. In general, the investors are suggested not to buy the GIAA and CMPP shares when the IDR exchange rate weakens against the US dollar exchange rate.
PERFORMANCE EVALUATION AND RISK AVERSION RATE FOR SEVERAL STOCK INDICES IN INDONESIA STOCK EXCHANGE Robiyanto, Robiyanto
Jurnal Manajemen dan Kewirausahaan Vol 19, No 1 (2017): MARCH 2017
Publisher : Institute of Research and Community Outreach - Petra Christian University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.9744/jmk.19.1.60-64

Abstract

There are numerous stock indices in Indonesia Stock Exchange. Several of them are LQ-45, MBX, DBX, JII, SRI-KEHATI, PEFINDO-25, BISNIS-27, IDX-30 and KOMPAS-100. Unfortunately there are limi­ted researches which have been done to measure those indices performance specifically. The same condition also occurs on risk aversion level usage in Indonesia Stock Exchange, only few numbers of researches use this me­a­surement in the portfolio valuation. Based on that, this research measured the performance and risk aversion rate of those indices in Indonesia Stock Exchange. The results of this study were SRI-KEHATI becomes the best performer with the highest risk aversion rate, while Jakarta Islamic Index (JII) produces the lowest positive per­formance with the lowest risk aversion rate. This finding shows that sharia stocks’ characters (i.e. usury free) could give relieveness and convenience regardless its per­formance.
Profil Penggunaan Antidiabetik pada Pasien Diabetes Melitus Gestasional di Puskesmas Wilayah Kecamatan Pontianak Kota Anisya, Kharina; Robiyanto, Robiyanto; Nurmainah, Nurmainah
Indonesian Journal of Clinical Pharmacy Vol 8, No 1 (2019)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2019.8.1.72

Abstract

Pada masa kehamilan, terjadi perubahan-perubahan fisiologis yang berpengaruh terhadap metabolisme karbohidrat sehingga mengakibatkan kehamilan tersebut bersifat diabetogenik. Berbagai faktor dapat mengganggu keseimbangan metabolisme karbohidrat dengan meningkatnya usia kehamilan sehingga terjadi gangguan toleransi glukosa. Keadaan ini dikenal dengan diabetes melitus gestasional (DMG). DMG termasuk jenis penyakit diabetes melitus (DM) yang terjadi pada saat kehamilan. DMG, jika tidak ditangani dengan tepat, dapat berisiko menjadi DM tipe 2 di masa mendatang. Untuk itu, pengobatan DMG perlu dilakukan dengan pendekatan nonfarmakologi dan farmakologi untuk mencegah terjadinya DM tipe 2 dalam jangka waktu yang panjang. Penelitian ini bertujuan untuk mendeskripsikan penggunaan antidiabetik pada pasien diabetes melitus gestasional di Puskesmas Wilayah Kecamatan Pontianak Kota. Penelitian ini menggunakan metode observasional dengan rancangan penelitian potong lintang yang bersifat deskriptif. Pengumpulan data dilakukan secara retrospektif berdasarkan data rekam medis pasien DMG rawat jalan di Puskesmas Wilayah Kecamatan Pontianak Kota periode Januari 2016–September 2017. Sampel penelitian yang memenuhi kriteria inklusi sebanyak 32 pasien. Dari hasil penelitian, diperoleh obat yang dominan digunakan untuk mengatasi DMG pada wanita hamil adalah metformin (78,13%) yang merupakan golongan biguanida, dan sisanya menggunakan gliburid (21,88%) yang merupakan golongan sulfonilurea. Simpulan dari penelitian ini adalah golongan biguanida banyak digunakan untuk mengatasi DMG pada wanita hamil trimester kedua dan ketiga.Kata kunci: Diabetes melitus gestasional, gliburid, metformin Antidiabetic Use Profile on Gestasional Diabetes Mellitus Patients at Community Health Center in Region of Center PontianakAbstractDuring pregnancy, there are physiological changes affecting on carbohydrate metabolism which cause a diabetogenic pregnancy. Various factors can disrupt the balance of carbohydrate metabolism with increasing gestational age, resulting in impaired glucose tolerance. This condition is known as gestational diabetes mellitus (GDM). GDM is a type of diabetes mellitus (DM) that occurs during pregnancy. GDM, if not handled properly, can be at risk of becoming type 2 DM in the future. Therefore, GDM treatment needs to be done with non-pharmacology and pharmacology approach to prevent the occurrence of DM type 2 in the long term. The objective of this research was to describe the use of oral antidiabetics on gestational diabetes mellitus patients at community health center in Region of Center Pontianak. This research employed observational method with descriptive cross-sectional study design. The data collection was done from medical record of gestasional diabetes mellitus outpatients at community health center in Region of Center Pontianak in the period of January 2016–September 2017. A total of 32 patients fulfilled the inclusion criteria. The results showed that drugs dominantly taken as GDM treatment during pregnancy was metformin (78.13%) which is biguanide group, while the rest was glyburide (21.88%) which is sulfonylurea group. The conclusion of this research is biguanide group was mostly used to treat GDM for pregnancy during the second trimester and third trimester.Keywords: Gestational diabetes mellitus, glyburide, metformin
Potensi Ekstrak Etanol Daun Petai (Parkia speciosa Hassk.) Terhadap Kadar Superoksida Dismutase (SOD) pada Plasma Tikus yang Mengalami Stres Oksidatif Butarbutar, Ruth Haryanti; Robiyanto, Robiyanto; Untari, Eka Kartika
Pharmaceutical Sciences and Research (PSR) Vol 3, No 2 (2016)
Publisher : Directorate of Research and Community Engagement, Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.7454/psr.v3i3.3539

Abstract

Cigarette smoke is free radicals superoxide resources that contains, hydrogen peroxide, hidrosil and peroksil. Superoxide dismutase (SOD) is an enzymatic antioxidant that protect cells from oxidative stress by catalize superoxide dismutase (O2*) into O2 and H2O2. The aimed of this study was to determine the potential of ethanolic extract of petai leaves against plasma SOD enzyme activity in animals that was exposed by cigarette smoke. The extract was made by maseration method using ethanol 96%. Thirty-six rats Sprague Dawley strain were divided into six groups:&nbsp; normal group was not given treatment, negative group received 10% CMC-Na, positive control group received vitamin E, and treatment group received ethanolic extract of petai leaves 50; 100; 250 mg/kgBW of mice. All rats were treated for 14 days. SOD activity was measured by UV-Visible spectrophotometer at a wavelength of 505 nm. Statistical analysis using One Way ANOVA. The mean value of SOD activity for normal, negative control, positive control and the group receiving the ethanolic extract of petai leaves dose of 50; 100; 250 mg/kg in a row is 37.979 &plusmn; 3708; 59.932 &plusmn; 3085; 48.552 &plusmn; 1234; 57.239 &plusmn; 2102; 50.774 &plusmn; 1632; 59.124 &plusmn; 4849. The result showed ethanolic extract of petai leaves affected on the activity of SOD was dose of 100 mg/kg.
The Volatility–Variability Hypotheses Testing and Hedging Effectiveness of Precious Metals for the Indonesian and Malaysian Capital Markets Robiyanto, Robiyanto; Wahyudi, Sugeng; Pangestuti, Irene Rini Demi
Gadjah Mada International Journal of Business Vol 19, No 2 (2017): May-August
Publisher : Master in Management, Faculty of Economics and Business, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/gamaijb.26260

Abstract

This study evaluates the use of futures contracts for precious metals to hedge against stock market risks and their hedging effectiveness on the Indonesian Stock Exchange (IDX) and the Kuala Lumpur Stock Exchange (KLSE). This study found that gold was the most effective hedging instrument, since it produced the highest hedging effectiveness both on the IDX and the KLSE among the other precious metals. None of the hedged portfolios had a higher Sharpe’s ratio than the unhedged one on the IDX; however, all the hedged portfolios on the KLSE had a higher Sharpe’s ratio than the unhedged ones. Almost all the hedged portfolios could produce a higher Treynor’s ratio than the unhedged portfolios, both on the IDX and the KLSE. In general, this study concluded that studying some precious metals could reduce the investment risk, which was shown through the variance produced by the smaller portfolios, while gold can improve the risk-adjusted performance.
THE INFLUENCE OF INFLATION RATE, BI RATE, AND EXCHANGE RATE TO THE FINANCIAL SECTOR INDEX RETURN IN THE INDONESIAN STOCK MARKET Yunita, Yunita; Robiyanto, Robiyanto
Jurnal Manajemen dan Kewirausahaan Vol 20, No 2 (2018): SEPTEMBER 2018
Publisher : Institute of Research and Community Outreach - Petra Christian University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.806 KB) | DOI: 10.9744/jmk.20.2.%p

Abstract

The objective of this study is to find out how macroeconomic factors such as exchange rate changes, BI rate and inflation rate can affect the financial sector stock price index in IDX from 2011 until 2017. Generalize Autoregressive Conditional Heteroscedasticity (GARCH) is used as the analysis method in this research to find the fittest model. The results are, only exchange rate change that has significant effect to financial sector stock price index. Inflation and BI rate has no significant effect to financial sector stock price index return.
THE EFFECT OF GOLD PRICE CHANGES, USD/IDR EXCHANGE RATE CHANGES AND BANK INDONESIA (BI) RATE ON JAKARTA COMPOSITE INDEX (JCI)’S RETURN AND JAKARTA ISLAMIC INDEX (JII)’S RETURN Robiyanto, Robiyanto
Jurnal Manajemen dan Kewirausahaan Vol 20, No 2 (2018): SEPTEMBER 2018
Publisher : Institute of Research and Community Outreach - Petra Christian University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.9744/jmk.20.1.%p

Abstract

This study examines the effect of gold price (in Rupiah) changes, US Dollar exchange rate changes against Rupiah (USD / IDR), and BI rate on Jakarta Composite Index (JCI) return and Jakarta Islamic Index (JII) return in Stock Exchange Indonesia during the period of June 2008 to September 2017. The data used in this study was obtained from the official website of Bank Indonesia and Bloomberg. Data analysis was done by using multiple regression techniques by previously doing classical assumption test. The result of this research is that the exchange rate of USD / IDR changes and BI rate have a significant negative effect on JCI return. The study also found that the USD / IDR exchange rate changes and BI rate have a significant negative effect on JII return, but the gold price (in Rupiah) changes has a significant positive effect on JII return.
PERFORMANCE EVALUATION AND RISK AVERSION RATE FOR SEVERAL STOCK INDICES IN INDONESIA STOCK EXCHANGE Robiyanto, Robiyanto
Jurnal Manajemen dan Kewirausahaan Vol 19, No 1 (2017): MARCH 2017
Publisher : Institute of Research and Community Outreach - Petra Christian University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (213.28 KB) | DOI: 10.9744/jmk.19.1.60-64

Abstract

There are numerous stock indices in Indonesia Stock Exchange. Several of them are LQ-45, MBX, DBX, JII, SRI-KEHATI, PEFINDO-25, BISNIS-27, IDX-30 and KOMPAS-100. Unfortunately there are limi­ted researches which have been done to measure those indices performance specifically. The same condition also occurs on risk aversion level usage in Indonesia Stock Exchange, only few numbers of researches use this me­a­surement in the portfolio valuation. Based on that, this research measured the performance and risk aversion rate of those indices in Indonesia Stock Exchange. The results of this study were SRI-KEHATI becomes the best performer with the highest risk aversion rate, while Jakarta Islamic Index (JII) produces the lowest positive per­formance with the lowest risk aversion rate. This finding shows that sharia stocks’ characters (i.e. usury free) could give relieveness and convenience regardless its per­formance.