Articles
12
Documents
The Role of Antioxidant to Prevent Free Radicals in The Body

Sains Medika Vol 8, No 1 (2017): January - June 2017
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

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Abstract

AbstractAntioxidants are compounds that can counteract or reduce the negative impact oxidants in the body. Antioxidants work by donating an electron to compounds that are oxidant so that the oxidant compound activity can be inhibited. Antioxidants are classified into two, namely antioxidant enzymes and non-enzyme. Antioxidant enzymes as enzyme superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx), a non-enzyme antioxidant found in many vegetables and fruits, which include reduced glutathione (GSH), vitamin C, E, β- carotene, flavonoids, isoflavones, flavones, antosionin, catechins, and isokatekin, and lipoic acid. Low antioxidant enzymes can be used as a marker of high levels of free radicals in the body. Following review aims to provide an overview of the role of antioxidants in preventing the formation of free radicals in the body.

The Behavioral Factor Associated with The Incidence of Malariain Endemic Area

Sains Medika Vol 3, No 2 (2011): Juli-Desember 2011
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

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Abstract

Background: Magelang Regency is one of the endemic area of malaria in central Java. The working area of Health centre of Kajoran I, Banjaretno, has the highest incidence of malaria annually (Dinkes Magelang, 2010). Malaria is is transmitted through the bite of female Anopheles infected by Plasmodium sp. Its most effective prevention is vector eradication. This study was aimed at finding out the behavioral risk for the incidence of malaria.Design and Methods: In this observasional study using case control design include 40 cases and 40 controls using the simple random sampling. Chi square test followed by double-logistic regression was applied for the data analysis with p=5%. Results: Bivariate analysis on the 6 factors resulted in p<0.05 and 2 factors resulted in p>0.05. multivariate analysis showed that the habit factor of going out in the evening, installing wire gauze on the ventilation, hanging used clothes, mowing lawn, the existence of closed waste basket, washing the curtain resulted in the p=0.010 (OR = 10; 95% CI = 3.4-39.2), p=0.001 (OR = 4.1; 95% CI = 3.5-15.8), p=0.018 (OR = 3.3; 95% CI = 1.9 -16.2), p=0.044 (OR = 6.5; 95% CI = 2.1-30.9), p=0.380 (OR = 0.43; 95% CI = 0.1-1.2), p=0.002 (OR = 2.4; 95% CI =3.4 -5.6) respectively.Conclusion: The habit of going out in the evening has been shown to be most important behavioral factor associated with the malaria incidence (Sains Medika, 3(2):168-184).

The Correlation between Individual and Environmental Hygiene and Pioderma Incidence An Analytical Observational Study in Pyoderma Patient in Islamic Sultan Agung Hospital during the Period August to December 2010

Sains Medika Vol 3, No 1 (2011): Januari-Juni 2011
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

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Abstract

Background: Bacterial skin infection is the third most common health problem in Indonesia resulting from poor personal and environmental hygiene. The most common bacterial skin infection is the pyoderma. This study aims to find out relation between personal hygiene and environmental with the incidence of pyoderma in RSI Sultan Agung Semarang.Design and Methods: The study type was analytic observational with case control design. The sample consisted of 30 respondents RSI patients Sultan Agung for case group and 30 persons as control group is the neighbors of patients who have similar characteristics and are not suffering pyoderma. The data used are secondary data from medical records and primary data from questionnaires filled out by respondents, then the data were analyzed with chi-square and to determine the correlation power there was used a contingency coefficient test.Results: It was found that the good and the bad individual hygene for the case group were 3.3% and 66.7% respectively, while for the control group the good and bad individual hygene were 80.0% and 20.0% respectively. Chi-square test resulted in p=0,000 with contingency coefisien of 0.426. It was found that the good and the bad environmental hygene for the case group were 56.7% and 43.3% respectively, while for the control group the good and bad environmental hygene were 83.3% and 16.3% respectively. Chi-square test resulted in p=0,024 with contingency coefisien of 0.27.Conclusion: There was a significant correlation between the personal and environmental hygiene and poderma insicence at the RSI Sultan Agung with a moderate relationship between individual hygiene and weak relationship between environmental hygene (Sains Medika, 3(1):24-30).

The Correlation between Medical Personnel’s Attitude and Pap Smear Examination Practice at Islamic Sultan Agung Hospital Semarang

Sains Medika Vol 7, No 1 (2016): January - June 2016
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

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Abstract

Introduction: Cervical cancer is still ranked in the first place of those diseases most commonly developing in Indonesian women. It is predicted that 41 new cases occur every day, and around 20 people every day pass away of it. Cervical cancer keeps increasing because the coverage of screening through pap smear examination is low. Objective: This research aims at discovering the correlation between medical personnel’s attitude and practice of pap smear examination at Rumah Sakit Islam Sultan Agung (RISA) Semarang. Methods: The study is observational research using cross sectional design with a sample of 38 medical personnel taken randomly from 273 personnel as its population in RISA Semarang. The data are taken using questionnaire and interview with respondents, and the obtained data are analyzed using univariate and bivariate tests, using chi-square test, at a significance level < 0.05. Result: the percentage of medical personnel having regular pap smear practice is higher in medical personnel with good attitude (66.7%) compared to those with poor attitude (17.6%). The data analysis using Chi Square statistic test indicates a significant difference, p = 0.003.Conclusion: the results of this reseach show that pap smear is more commonly done by those medical personnel with good attitude than those with poor attitude