Achmad Zaki
Staf Pengajar Program Studi Pendidikan Dokter Fakultas Kedokteran dan Ilmu Kesehatan Universitas Islam Negeri Syarif Hidayatullah Jakarta

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Comparison of fracture site callus with iliac crest bone marrow as the source of plastic-adherent cells Zaki, Achmad; D., Ismail H.
Medical Journal of Indonesia Vol 22, No 2 (2013): May
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (571.448 KB) | DOI: 10.13181/mji.v22i2.531

Abstract

Background: Red marrow has been described as the main source of mesenchymal stem cells although its aspiration and isolation from bone marrow was reported to have significant donor site morbidity. Since secondary bone healing occurs through formation of callus as the result of proliferation and differentiation of mesenchymal stem cells, callus may become alternative source for mesenchymal stem cells. In this study, we compared the number of plastic-adherent cells from fracture site callus and bone marrow of iliac crest after two and four weeks of culture.Methods: Sixteen New Zealand rabbits were fracturized at the femoral shaft. Then, these rabbits were taken care. After two weeks of fracturization, 3 mL iliac crest bone marrow aspiration and callus extraction of eight rabbits were cultured (group I). The other eight rabbits were treated equally after four weeks of fracturization (group II). Simultaneously, the cultures were observed after one and two weeks. Four weeks later, they were harvested. Cells were counted using Neubauer hemocytometer. The average number of cells between the sources and groups were statistically analyzed using the unpaired t-test. Results: In group I, there were 2.6 ± 0.1 x 104 cells in the culture of iliac crest bone marrow aspirate and 2.5 ± 0.1 x 104 cells in culture of callus extract from fracture site (p = 0.34). In group II, there were 2.7 ± 0.1 x 104 cells and 2.1 ± 0.1 x 104 cells, respectively (p < 0.001).Conclusion: Fracture site callus at the second week post-fracturization may be potential as source of plastic-adherent cells compared with iliac crest bone marrow. (Med J Indones. 2013;22:70-5)Keywords: Bone marrow, fracture site callus, iliac crest, long bone, mesenchymal stem cell, plastic-adherent cells
Hubungan Aktivitas Fisik Berat dengan Back Pain pada Penduduk Usia Kerja di Jawa dan Bali Zaki, Achmad
Jurnal Kesehatan Masyarakat Nasional Vol. 2 No. 4 Februari 2008
Publisher : Faculty of Public Health Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (209.556 KB) | DOI: 10.21109/kesmas.v2i4.263

Abstract

Penelitian ini bertujuan mengetahui hubungan lama aktivitas fisik berat dengan Gejala Back pain pada penduduk usia kerja 18 – 55 tahun di wilayah Pulau Jawa dan Bali. Penelitian ini menggunakan data sekunder Survei Kesehatan Nasional Tahun 2001. Penelitian ini menggunakan desain potong-lintang dengan metode analisis regresi logistik ganda. Hasil penelitian mendapatkan ada hubungan antara aktivitas fisik berat dengan gejala back pain, setelah dikontrol oleh variabel-variabel confounding seperti lama aktivitas fisik duduk atau sedikit berjalan (terkait pekerjaan ataupun tidak), jenis kelamin, dan pendidikan. Responden dengan lama aktivitas fisik berat (bekerja 1-5 jam) memiliki risiko 2,03 kali untuk mengalami gejala back pain dibandingkan kelompok yang tidak melakukan aktifitas fisik berat (95% CI 1,34-3,08). Responden dengan lama aktivitas fisik berat (bekerja >5 jam) memiliki risiko 1,60 kali untuk mengalami gejala back pain dibandingkan kelompok yang tidak melakukan aktifitas fisik berat (95% CI 0,55 - 4,63). Disarankan untuk pemberlakuan regulasi waktu kerja menggunakan metode waktu rehat pendek (short rest break), dimana pekerja yang harus bekerja selama 5-6 jam terus menerus perlu diistirahatkan di pertengahan waktu tersebut selama sekitar 20 menit.Kata kunci: Aktivitas fisik, back painAbstractThe objective of this research is to investigate the relationship between high occupational physical activity with back pain symptoms among working age population (18—55 years olds) in Java and Bali islands. This research used secondary data from National Health Survey 2001. This research was using the crosssectional design and was analyzed by multiple logistic regression. The study result shows that there are a relationship between high occupational physical activity with back pain symptoms after controlled with confounding variables such as: duration of occupational sitting and short walk activity, duration of nonoccupational sitting and short walk, gender and educational status. Respondents with duration of heavy occupational activity of 1-5 hours have 2,03 higher risk to get back pain symptoms compared to those not doing it (95% CI 1,34-3,08). Respondents with duration of heavy occupational activity of >5 hours have 1,60 risk to get back pain symptoms compared to those not doing it (95% CI 0,55 - 4,63).Keywords : Physical activity, back pain
Peningkatan Ketebalan Serat Elastin Dinding Vagina pada Prolapsus Organ Pelvis Anterior Zaki, Achmad; Mardian, Eighty; Mustokoweni, Sjahjenny
Majalah Obstetri & Ginekologi Vol 24, No 1 (2016): Januari - April
Publisher : Department of Obstetrics and Gynecology, Faculty of Medicine, Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V24I12016.31-36

Abstract

Objectives: To measure the thickness of elastin fibres on vaginal wall of patients with POP anterior and then analyse the correlation of this measurement with the degree of POP anterior.Materials and Methods: This research is an observational analytic study. Data collection was conducted with a cross sectional approach on 28 blocks paraffin of vaginal wall taken from POP anterior patients of whom went through an operation in Dr. Soetomo Hospital of Surabaya. Data was divided into four groups: degree 0/I , II, III and IV respectively (n = 7). Immunohistochemical staining was performed with antibodies elastin. Afterward, the thickness of the elastin fibres was measured by utilizing a microscope with a Leica Application Suite (LAS) software.Results: We found significant differences in the mean of thickness of elastin fibres in each group of patients with degrees of anterior POP 0/I , II , III and IV respectively 0,81 + 0,14 µm; 1,63 + 0,19 µm; 2,47 + 0,26µm and 3,19 + 0,36 µm (p < 0,0001 ). Based on Pearson correlation test, the results shows a correlation coefficient r = 0.965 (p < 0,0001).Conclusion: The thickness of elastin fibre on vaginal wall increased as the degree of POP anterior arise. Increased in the thickness of elastin fibers on the vaginal walls was the result from extracellular matriks remodelling on vaginal wall of anterior POP patient.
Peningkatan Ketebalan Serat Elastin Dinding Vagina pada Prolapsus Organ Pelvis Anterior Zaki, Achmad; Mardian K, Eighty; Mustokoweni, Sjahjenny
Majalah Obstetri & Ginekologi Vol 24, No 1 (2016): Januari - April 2016
Publisher : Majalah Obstetri & Ginekologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.v24i1.2763

Abstract

Tujuan: Mengukur ketebalan serat elastin pada dinding vagina penderita POP anterior dan menganalisis korelasi antara ketebalan serat elastin dengan derajat POP anterior.Bahan dan Metode: Penelitian ini merupakan penelitian analitik observasional secara cross sectional yang dilakukan pada 28 blok paraffin dinding vagina dari penderita POP anterior yang telah dilakukan operasi di RSUD dr. Soetomo Surabaya. Dibagi menjadi 4 kelompok: derajat 0/I, II, III dan IV dengan masing-masing (n=7). Dilakukan pewarnaan imunohistokimia dengan antibodi elastin dilanjutkan pengukuran ketebalan serat elastin menggunakan mikroskop dengan perangkat lunak Leica Application Suite (LAS).Hasil: Didapatkan perbedaan bermakna rerata ketebalan serat elastin kelompok penderita POP anterior derajat 0/I, II, III dan IV yaitu masing-masing sebesar 0,81 + 0,14 µm; 1,63 + 0,19 µm; 2,47 + 0,26µm dan 3,19 + 0,36 µm (p<0,0001). Berdasarkan hasil uji statistik korelasi pearson didapatkan koefisien korelasi r = 0,965 (P<0,0001).Simpulan: Ketebalan serat elastin pada dinding vagina bertambah dengan meningkatnya derajat POP anterior. Peningkatan ketebalan serat elastin merupakan akibat proses remodeling matriks ekstraseluler pada dinding vagina penderita POP anterior.
Hubungan Aktivitas Fisik Berat dengan Back Pain pada Penduduk Usia Kerja di Jawa dan Bali Zaki, Achmad
Jurnal Kesehatan Masyarakat Nasional Vol. 2 No. 4 Februari 2008
Publisher : Faculty of Public Health Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (209.556 KB) | DOI: 10.21109/kesmas.v2i4.263

Abstract

Penelitian ini bertujuan mengetahui hubungan lama aktivitas fisik berat dengan Gejala Back pain pada penduduk usia kerja 18 – 55 tahun di wilayah Pulau Jawa dan Bali. Penelitian ini menggunakan data sekunder Survei Kesehatan Nasional Tahun 2001. Penelitian ini menggunakan desain potong-lintang dengan metode analisis regresi logistik ganda. Hasil penelitian mendapatkan ada hubungan antara aktivitas fisik berat dengan gejala back pain, setelah dikontrol oleh variabel-variabel confounding seperti lama aktivitas fisik duduk atau sedikit berjalan (terkait pekerjaan ataupun tidak), jenis kelamin, dan pendidikan. Responden dengan lama aktivitas fisik berat (bekerja 1-5 jam) memiliki risiko 2,03 kali untuk mengalami gejala back pain dibandingkan kelompok yang tidak melakukan aktifitas fisik berat (95% CI 1,34-3,08). Responden dengan lama aktivitas fisik berat (bekerja >5 jam) memiliki risiko 1,60 kali untuk mengalami gejala back pain dibandingkan kelompok yang tidak melakukan aktifitas fisik berat (95% CI 0,55 - 4,63). Disarankan untuk pemberlakuan regulasi waktu kerja menggunakan metode waktu rehat pendek (short rest break), dimana pekerja yang harus bekerja selama 5-6 jam terus menerus perlu diistirahatkan di pertengahan waktu tersebut selama sekitar 20 menit.Kata kunci: Aktivitas fisik, back painAbstractThe objective of this research is to investigate the relationship between high occupational physical activity with back pain symptoms among working age population (18—55 years olds) in Java and Bali islands. This research used secondary data from National Health Survey 2001. This research was using the crosssectional design and was analyzed by multiple logistic regression. The study result shows that there are a relationship between high occupational physical activity with back pain symptoms after controlled with confounding variables such as: duration of occupational sitting and short walk activity, duration of nonoccupational sitting and short walk, gender and educational status. Respondents with duration of heavy occupational activity of 1-5 hours have 2,03 higher risk to get back pain symptoms compared to those not doing it (95% CI 1,34-3,08). Respondents with duration of heavy occupational activity of >5 hours have 1,60 risk to get back pain symptoms compared to those not doing it (95% CI 0,55 - 4,63).Keywords : Physical activity, back pain
Model Fuzzy Tsukamoto untuk Klasifikasi dalam Prediksi Krisis Energi di Indonesia Zaki, Achmad; Santoso, Heru Agus
Creative Information Technology Journal Vol 3, No 3 (2016): Mei - Juli
Publisher : UNIVERSITAS AMIKOM YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (846.548 KB) | DOI: 10.24076/citec.2016v3i3.76

Abstract

Krisis energi dunia juga terjadi di Indonesia. Cadangan energi di Indonesia terutama energi fosil (minyak bumi, batubara, dan gas alam) semakin hari semakin menyusut. Ketersediaan akan energi fosil juga semakin berkurang karena peningkatan konsumsi energi per kapita. Untuk memprediksi krisis energi di Indonesia, paper ini mengusulkan pengembangan sistem inferensi fuzzy sukamoto untuk klasifikasi krisis energi berdasarkan parameter jumlah produksi, konsumsi energi dan faktor penggerak kebutuhan energi, yakni GDP dan populasi penduduk. Luaran dari sistem ini adalah klasifikasi berdasarkan parameter tersebut, yaitu kondisi aman, waspada dan krisis. Hasil eksperimen menunjukan sistem yang dibangun menghasilkan tingkat akurasi pada minyak bumi 90%, batubara 100 % dan gas alam 100%. Dengan adanya sistem ini diharapkan mampu memberikan peringatan dini dan pendukung keputusan bagi pemerintah atau pihak instansi terkait dalam memberikan penangan atau solusi terhadap masalah krisis energi. World energy crisis also occurred in Indonesia. Energy reserves in Indonesia, especially fossil fuels (petroleum, coal, and natural gas) are increasingly shrinking. The availability of fossil energy will also be on the wane because of an increase in energy consumption per capita. To predict the energy crisis in Indonesia, this paper proposes the development of sukamoto fuzzy inference systems for classification energy crisis based on parameters the amount of production, energy consumption and energy demand driven factors, namely GDP and population. Outcomes of this system is the classification based on these parameters, i.e., a safe condition, alert and crisis. The experimental results show the system produce levels of accuracy at 90% petroleum, natural gas 100% and CoA, 100%. This system are expected to provide an early warning and decision support for the government or the relevant agencies in giving the handlers or the solution to the problem of energy crisis. 
STRATEGIES FOR SUCCESSFUL FAMILY-OWNED BUSINESS Zaki, Achmad; Rahayu, Mintarti; Susilowati, Christin
Jurnal Aplikasi Manajemen Vol 16, No 2 (2018)
Publisher : Jurusan Manajemen Fakultas Ekonomi dan Bisnis Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jam.2018.016.02.04

Abstract

This study aimed at explaining the strategies of success in running family-owned enterprise to enable the next generation to develop the company which had been established by previous generations. This was a qualitative research with a case study approach conducted on military equipment business inTulungagung Regency. The results of this study indicated that the strategies of success in family-owned companies were through the process of selection of candidates for the next generation of the company and handing over all power to the elected candidates. Conflicts emerged inside the process of selection or determination of business leaders but through meetings orde liberation with all members of the second generation and produced an agreement that three of the six children of the family went into the organizational structure to manage the business. While the other three children set up their own business, however, the three children were still related to the development of family companies.