Fransiska R. Zakaria
Departemen Ilmu dan Teknologi Pangan, Fakultas Teknologi Pertanian, Institut Pertanian Bogor, Bogor

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AKTIVITAS ANTIOKSIDAN EKSTRAK DIKHLOROMETANA DAN AIR JAHE (Zingiber officinale Roscoe) PADA ASAM LINOLEAT [Antioxidant Activity of Ginger (Zingiber officinale Roscoe) Dichloromethane and Water Exctract on Linoleic Acid] Septiana, Aisyah Tri; Muchtadi, Deddy; Zakaria, Fransiska R.
Jurnal Teknologi Dan Industri Pangan Vol 13, No 2 (2002): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.6066/4336

Abstract

 AKTIVITAS ANTIOKSIDAN EKSTRAK  DIKHLOROMETANA DAN AIR JAHE  (Zingiber officinale Roscoe) PADA ASAM LINOLEAT  [Antioxidant Activity of Ginger (Zingiber officinale Roscoe) Dichloromethane and Water Exctract  on Linoleic Acid] Aisyah Tri Septiana 1) , Deddy Muchtadi 2)  dan Fransiska R. Zakaria 2) 1) Jurusan Teknologi Pertanian, Fakultas Pertanian, UNSOED Purwokerto 2) Program Studi Ilmu Pangan, Fakultas Teknologi Pertanian, IPB-Bogor ABSTRACT     Antioxidant activity of various ginger extracts are different.  The aims of this work are to determine the antioxidant activity of ginger extracts on linoleic acid. The antioxidant activities were tested on  linoleic acid supplemented with water and dichloromethane extract of ginger.   The antioxidant  activity was tested by measuring malonaldehide absorbance.  Total phenol and iron content  of the extracts were analyzed by spectrometry.  This research showed that antioxidant activity of water and dichloromethane extract of ginger was stronger than a-tocopherol, and antioxidant activity of dichloromethane extract is stronger than water extract of ginger.  Antioxidant activity of ginger extracts, seems to be correlated with  the  total phenol and iron contents.   Key  words :  Antioxidant, linoleic acid, dichloromethane, malonaldehide, and extract of ginger.
EFEK KONSUMSI MINUMAN BUBUK KAKAO (Theobroma cacao L.) BEBAS LEMAK TERHADAP SIFAT ANTIOKSIDATIF LIMFOSIT SUBYEK PEREMPUAN [The Effect of Fat Free Cocoa (Theobroma Cacao L.) Powder Drinks Consumption on Antioxidative Activity of Lymphocyte of Women Subjec Erniati, .; Zakaria, Fransiska R.; Priosoeryanto, Bambang Pontjo
Jurnal Teknologi Dan Industri Pangan Vol 23, No 1 (2012): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.6066/5299

Abstract

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Analisis Persepsi Konsumen terhadap Produk Minyak Sawit Merah Sebagai Minyak Kesehatan (Studi Kasus: Perumahan Ciomas Permai, Bogor) Bardhani, Muhammad Alif; Zakaria, Fransiska R.; Palupi, Nurheni Sri
MANAJEMEN IKM: Jurnal Manajemen Pengembangan Industri Kecil Menengah Vol 4, No 2 (2009): Manajemen IKM
Publisher : Institut Pertanian Bogor

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Product of red palm oil is a new product which is still not marketed yet insufficient quantity so that it is not recognized by many people. Because of that, it needs promotion about the benefit and quality for the consumer. The approach in this research is market or selling the product of red palm oil to the respondent through direct marketing (door to door), and at the same time do the analysis of consumer’s perception to the product of red palm oil. In general the aim of this research is to know consumer’s perception in getting decision of buying and strategy alternative which can be done in marketing of red palm oil in Perumahan Ciomas Permai, Bogor. Location of this research is in Perumahan Ciomas Permai, Blok B Desa Ciapus Kecamatan Ciomas Kabupaten Bogor. The method of this research is case study with descriptive and quantitative analysis with multiple regression. The processing and data analysis were done with application of Microsoft Excel, which is shown in the form of tabulation and correlation matrix and analysis multiple regression linear with counting use computer program SPSS. The number of respondent were 35 people who represent middle household. Based on the research, through direct marketing and consumer’s analysis, it was found that there were four factors which influence the process of buying decision red palm oil namely price, color, content of nutrient and the packaging. The strategy of marketing which can be done for the product of red palm oil is maintain and improve the quality of red palm oil (the hygienic control, quality, purity, color and nutrient content), giving a discount in a certain sales, promotion by distributing brochure and leaflet, service of delivery and guarantee the continuity of red palm oil availability.   Key words:       direct marketing, consumer’s analysis, red palm oil, multiple regression linear, decision of buying
PENGARUH EKSTRAK JAMU TERHADAP AKTIVITAS SEL NATURAL KILLER DALAM MELISIS ALUR SEL LEUKIMIA (K-562) SECARA IN VITRO [The Effects of Commercial “Jamu” Extracts on Natural Killer Cell Activity in Lysing Leukemic Cell Line (K-562 ) in vitro] Zakaria, Fransiska R.; D.C., Elisa Veronica
Jurnal Teknologi Dan Industri Pangan Vol 12, No 1 (2002): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.6066/7019

Abstract

PENGARUH EKSTRAK JAMU TERHADAP AKTIVITAS SEL NATURAL KILLER DALAM MELISIS ALUR SEL LEUKIMIA (K-562) SECARA IN VITRO [The Effects  of Commercial “Jamu” Extracts on Natural Killer Cell  Activity in Lysing Leukemic Cell Line (K-562 ) in vitro] Fransiska R. Zakaria 1) , dan Elisa Veronica D.C. 2) 1) Jurusan Teknologi Pangan dan Gizi, Fateta-IPB                       2) Alumni Jurusan Teknologi Pangan dan Gizi, Fateta-IPB ABSTRACT Natural killer (NK) cell consitutes white blood cells which specifically functions in lysing tumor and virus invected cells. In this research, a commercial “Jamu”  was tested to observe its effect on NK cells activity against leukemic cell lines (K562) in vitro. Jamu was extracted with hot water, diluted and added into cell cultures consisted of a mixture of human peripheric limphocyte cells, as the source of the effector NK cells, and K562 cell line i.e., the target cells which were cell line derived from human leukemia and had been labelled with H3-thymidine. The mixture of the cells were made by culturing the two cells at the ratio of 50:1 and 100 : 1, respectively. The results showed that lysing activity of NK cells in the presence of “Jamu” water extract measured as lysing percentage and lysing index increased only slightly, which were not statiscally significant. It should be considered that the test used in this research represents only a part of the lysing mechanism by NK cells against the target cells.  An in vivo test  for a period of time will be recessary to elucidate ffurther this NK cell activity. Key words : “ Natural Killer” Cell, Leucemic, Cell Line,  and  “jamu“  extracts  
PENGHAMBATAN EKSTRAK SORGUM (Sorghum Bicolor) TERHADAP PROLIFERASI SEL KANKER LIMFOMA Salimi, Yuszda K.; Zakaria, Fransiska R.
Sainstek VOL 06, NO 05, 2012
Publisher : Sainstek

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Abstract

Cancer is a disease caused by irregular and uncontrolled cell growth. Sorghum (Sorghum bicolor) contains antioxydant substances and fiber, supposed to have anticancer property. The aim of this research is to examine the inhibitory effect of whole sorghum (S0) and half polished (S50) sorghum grain extract on proliferating lymphoma cancer cell Raji. Extraction of sorghum grain used extraction method based on solvent polarity of hexane, ethyl acetate and ethanol. Cytotoxic testing lethal concentration 50 (LC50) was done by BSLT method. Lymphocyte proliferative activity and inhibition of cancer cells were conducted by MTT method. The extract were also able to increase cell proliferation of lymphocytes (2-71%). Sorghum extract could inhibit the growth of Raji cells ( 80.08%). The results showed that sorghum extract could inhibit cancer cell proliferation.
PENGARUH EKSTRAK JAMU TERHADAP AKTIVITAS SEL NATURAL KILLER DALAM MELISIS ALUR SEL LEUKIMIA (K-562) SECARA IN VITRO [The Effects of Commercial “Jamu” Extracts on Natural Killer Cell Activity in Lysing Leukemic Cell Line (K-562 ) in vitro] Zakaria, Fransiska R.; D.C., Elisa Veronica
Jurnal Teknologi dan Industri Pangan Vol 13, No 1 (2002): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Natural killer (NK) cell consitutes white blood cells which specifically functions in lysing tumor and virus invected cells. In this research, a commercial ?Jamu?  was tested to observe its effect on NK cells activity against leukemic cell lines (K562) in vitro. Jamu was extracted with hot water, diluted and added into cell cultures consisted of a mixture of human peripheric limphocyte cells, as the source of the effector NK cells, and K562 cell line i.e., the target cells which were cell line derived from human leukemia and had been labelled with H3-thymidine. The mixture of the cells were made by culturing the two cells at the ratio of 50:1 and 100 : 1, respectively. The results showed that lysing activity of NK cells in the presence of ?Jamu? water extract measured as lysing percentage and lysing index increased only slightly, which were not statiscally significant. It should be considered that the test used in this research represents only a part of the lysing mechanism by NK cells against the target cells.  An in vivo test  for a period of time will be recessary to elucidate ffurther this NK cell activity.
AKTIVITAS ANTIOKSIDAN EKSTRAK DIKHLOROMETANA DAN AIR JAHE (Zingiber officinale Roscoe) PADA ASAM LINOLEAT [Antioxidant Activity of Ginger (Zingiber officinale Roscoe) Dichloromethane and Water Exctract on Linoleic Acid] Septiana, Aisyah Tri; Muchtadi, Deddy; Zakaria, Fransiska R.
Jurnal Teknologi dan Industri Pangan Vol 13, No 2 (2002): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

    Antioxidant activity of various ginger extracts are different.  The aims of this work are to determine the antioxidant activity of ginger extracts on linoleic acid. The antioxidant activities were tested on  linoleic acid supplemented with water and dichloromethane extract of ginger.   The antioxidant  activity was tested by measuring malonaldehide absorbance.  Total phenol and iron content  of the extracts were analyzed by spectrometry.  This research showed that antioxidant activity of water and dichloromethane extract of ginger was stronger than a-tocopherol, and antioxidant activity of dichloromethane extract is stronger than water extract of ginger.  Antioxidant activity of ginger extracts, seems to be correlated with  the  total phenol and iron contents. 
EFEK KONSUMSI MINUMAN BUBUK KAKAO (Theobroma cacao L.) BEBAS LEMAK TERHADAP SIFAT ANTIOKSIDATIF LIMFOSIT SUBYEK PEREMPUAN [The Effect of Fat Free Cocoa (Theobroma Cacao L.) Powder Drinks Consumption on Antioxidative Activity of Lymphocyte of Women Subjec Erniati, .; Zakaria, Fransiska R.; Priosoeryanto, Bambang Pontjo
Jurnal Teknologi dan Industri Pangan Vol 23, No 1 (2012): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

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Abstract

The health benefits of cocoa both in vivo and in vitro have been reported in many studies. Cocoa is a rich source of flavonoids known to have antioxidant activity, such as catechin, epicatechin and procyanidin. The aim of this research was to evaluate the effect of fat free cocoa powder drink consumption on antioxidative properties and proliferation activities of woman lymphocyte. Healthy woman subjects were divided into cocoa group (n = 9) and control group (n = 9). Cocoa powder drink containing skim milk and sugar was given to the cocoa groups every morning for 25 days. The control group received only water containing skim milk and sugar. Both cocoa and control group received physical medical checkup at the beginning and at the end of the intervention. Their peripheral blood was taken for lymphocyte antioxidant analysis. The measured antioxidant properties consisted of antiradical activity by DPPH method, malonaldehyde (MDA) and glutathione levels. The data of cocoa group showed that there was a significant increase (p ? 0.05) in antiradical level from 31+11.2 to 40.19+7.42% and glutathione from 48.2±10.5 to 66.7±15.9 ?mol/land a decrease in MDA level in the lymphocyte (p < 0.05) from 2.98±2.21 to 1.29±0.33 ?mol/las compared to the control group (from 25.77±6.9 to 26.79±6.12%; 34.7±20.7 to 37.8±19.2 ?mol/land 3.01±1.53 to 2.069±0.707 ?mol/l respectively) after consumption of the cocoa powder drink. The results of this research revealed that fat free cocoa powder has a strong antioxidant activity which was manifested up to the blood cells.
PENGARUH MINUMAN DIPERKAYA CINNULIN TERHADAP MDA DAN SENYAWA INFLAMASI PLASMA PENDERITA DMT2 Putri S., Nawasari Indah; Prangdimurti, Endang; Zakaria, Fransiska R.
Jurnal Teknologi dan Industri Pangan Vol 27, No 1 (2016): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.6066/jtip.2016.27.1.51

Abstract

 Cinnamon has been used as a traditional treatment for thousands of years. Aqueous cinnamon extract namely cinnulin is known to have  positive effects on type-2 diabetes mellitus (T2DM). We aimed to study the effect of cinnulin enriched drink rich in polyphenols on plasma malondialdehyde (MDA), interleukin-6 (IL-6) and cyclooxygenase-2 (COX-2) in T2DM patients. 255 mg of cinnulin was mixed with tea extract into a 2.5 gram of instant drink with alumunium foil as the packaging material. A single blind study were performed on 33 respondents with T2DM from Dramaga District. Respondents were divided into three groups, i.e. group given cinnulin enriched drink (1), instant tea drink (2), and none of the products (control) (3). Group 1 and 2 were assigned to drink two sachetsof the products a day for 5 weeks. The MDA content of all groups remain unchanged after treatment although slightly increased (Wilcoxon, P>0.050) and no differences between groups was observed (P>0.050) suggesting that high phenolic content in the producst cause a reverse effect. Both inflammation marker (IL-6 and COX-2) decreased significantly for groups given cinnulin enriched drink and instant tea, whereas there is a significant increase for IL-6 and a significant decrease for COX-2 in control group. These results conclude that cinnulin enriched drink can be used as an antiinflammation drink for T2DM.
PERBAIKAN STATUS ANTIOKSIDAN PENDERITA DIABETES TIPE 2 DENGAN TAHU KEDELAI HITAM KAYA SERAT Triandita, Nanda; Zakaria, Fransiska R.; Prangdimurti, Endang; Putri, Nela Eska
Jurnal Teknologi dan Industri Pangan Vol 27, No 2 (2016): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.6066/jtip.2016.27.2.123

Abstract

Type 2 diabetes mellitus (T2DM) is a non-insulin dependent diabetes, because insulin is not secreted by beta cell pancreas or dysfunction of insulin reseptors. The purposes of this research were to evaluate the effect of dietary fiber rich- tofu from black soybean on the antioxidant plasma status, malonaldehide (MDA) and hepatic marker in T2DM patients. One group (n=11) of patients was given 80 g of tofu for 30 days while the control group (n=11) was not. No significant differences was observed pertaining the characteristics of both groups before interventions (age, body mass index, body weight, body high, systolic blood pressure, diastolic blood pressure and fasting blood glucose). The antioxidant activity, MDA and AST/ALT of both groups were analyzed from plasma at day-0 and day-30. Antioxidant activity was analyzed by DPPH method, MDA level with TBARS method, and AST/ALT by International Federation of Clinical Chemistry (IFCC) method. The result showed that the plasma antioxidant increased (4.77±9.49%), but the MDA (2.11±1.73 nmol/mL) and AST (7.73±16.72 U/L)/ ALT (3.55±12.79 U/L) level decreased. Rich dietary fiber tofu from black soybean may have potential use for improving the health status of T2DM patients.