Tetty Yuniaty
Department of Child Health, Faculty of Medicine, Universitas Padjadjaran-Dr. Hasan Sadikin General Hospital

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TYT Curve : Pilot Study on Alternatives Standards of Reference to Determine Intrauterine Growth in Low Resource Setting In Indonesia

International Journal of Integrated Health Sciences VOL 2, NO 1, July (2014)
Publisher : International Journal of Integrated Health Sciences

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Abstract

Objective: To develop a new intrauterine growth curve based on local population for accurate intrauterine growth retardation (IUGR) infant identification. Methods: An observational analytic method was applied to develop Tina-Yessika-Tetty (TYT) curve derived from 13,405 neonatal anthropometric measurements taken from the medical record database of Dr. Hasan Sadikin General Hospital, Bandung, Indonesia. The infants included in this study were born during the period of January 1st, 2005 to December 31st, 2009. The new curve was then compared to the Lubchenco and Alisjahbana curves. Only 6,814 data met the inclusion and exclusion criteria.    Results: The mean birth weight in this study was lower compared to that of the Lubchenco and Alisjahbana studies. Comparison of the three curves showed that there was a significant difference among the three curves (R=0.998, R2=0.996, p<0.001), which indicates a probability for a newborn classification.Conclusions: TYT curve may be used as an alternative to identify IUGR immediately after birth, especially when detection during pregnancy is not available in low resource setting. A prospective study with a larger population is needed; However, this study has provided an evidence to support the need for timely evaluation for such growth chart as they change over time.    Keywords: Alisjahbana curve, intrauterine growth, Lubchenco curve, TYT curveDOI: 10.15850/ijihs.v2n1.271

Validitas Skoring Hematologi Rodwell Untuk Deteksi Dini Sepsis Neonatorum Awitan Dini

Sari Pediatri Vol 16, No 5 (2015)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

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Abstract

Latar belakang. Sepsis neonatorum awitan dini adalah sindrom klinis dengan gejala infeksi sistemik yangmerupakan penyebab utama kesakitan dan kematian pada neonatus. Diagnosis sepsis neonatorum seringkalisulit karena gejala klinisnya tidak khas. Pemeriksaan biakan darah sebagai baku emas, memerlukan waktu48-72 jam. Sistem skoring hematologi (SSH) Rodwell dapat digunakan sebagai alat bantu deteksi dinisepsis neonatorum awitan dini.Tujuan. Menentukan nilai sensitivitas dan spesifisitas SSH Rodwell dalam mendeteksi sepsis neonatorumawitan dini.Metode. Penelitian deskriptif dengan rancangan potong lintang dilakukan di RSUP dr. Hasan SadikinBandung antara bulan September sampai November 2013. Subjek penelitian adalah neonatus berumurkurang atau sama dengan 5 hari dengan faktor risiko sepsis neonatorum.Hasil. Pada neonatus ditemukan hasil biakan darah positif 45 (40,9%) subjek. Sistem skoring hematologiRodwell memiliki sensitivitas 100% dan spesifisitas 66% untuk mendeteksi sepsis neonatorum awitandini.Kesimpulan. Pemeriksaan SSH Rodwell memiliki nilai sensitivitas tinggi dan nilai spesifisitas sedang dalammenegakkan diagnosis sepsis neonatorum awitan dini.

TYT Curve : Pilot Study on Alternatives Standards of Reference to Determine Intrauterine Growth in Low Resource Setting In Indonesia

International Journal of Integrated Health Sciences Vol 2, No 1 (2014)
Publisher : International Journal of Integrated Health Sciences

Show Abstract | Original Source | Check in Google Scholar

Abstract

Objective: To develop a new intrauterine growth curve based on local population for accurate intrauterine growth retardation (IUGR) infant identification. Methods: An observational analytic method was applied to develop Tina-Yessika-Tetty (TYT) curve derived from 13,405 neonatal anthropometric measurements taken from the medical record database of Dr. Hasan Sadikin General Hospital, Bandung, Indonesia. The infants included in this study were born during the period of January 1st, 2005 to December 31st, 2009. The new curve was then compared to the Lubchenco and Alisjahbana curves. Only 6,814 data met the inclusion and exclusion criteria.    Results: The mean birth weight in this study was lower compared to that of the Lubchenco and Alisjahbana studies. Comparison of the three curves showed that there was a significant difference among the three curves (R=0.998, R2=0.996, p<0.001), which indicates a probability for a newborn classification.Conclusions: TYT curve may be used as an alternative to identify IUGR immediately after birth, especially when detection during pregnancy is not available in low resource setting. A prospective study with a larger population is needed; However, this study has provided an evidence to support the need for timely evaluation for such growth chart as they change over time.    Keywords: Alisjahbana curve, intrauterine growth, Lubchenco curve, TYT curveDOI: 10.15850/ijihs.v2n1.271

Impact of Bifidobacterium lactis supplementation on fecal microbiota in infants delivered vaginally compared to Caesarean section

Paediatrica Indonesiana Vol 53 No 2 (2013): March 2013
Publisher : Indonesian Pediatric Society

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Abstract

Background It has been reported that infants born by Caesareansection have altered gut microbiota, with lower n umbers ofbifidobacteria and Bacteroides, compared to that of infants whowere delivered vaginally. Probiotic supplementation has beenreported to have beneficial effects on the immune response,generally in relation to allergies.Objective To assess the effect of Bifidobacterium lactis (B. lactis)supplementation on the presence of B. lactis and bifidobacteriacounts in stool of infants during the first 2 months of life .Methods We conducted an observational study of 122 healthy,breast-fed infants delivered vaginally or by Caesarean section.Infants assigned to the test group received breast milk and formulasupplemented with the B. lactis probiotics. Infants in the controlgroup received breast milk and formula without probiotics.The presence of B. lactis and stool bifidobacteria counts weredetermined at 1 month and 2 months of age. Growth, morbidity,serum immune markers, and stool immunoglobulin (lg) A werealso assessed.Results B. lactis was more frequently detected in the stool ofinfants who received breast milk and probiotic-supplementedformula than in stool of infants who received breast milk andnon-supplemented formula, both at 1 month and 2 months ofage (OR 1,263; 95%Cl 11 to 15 1,030; P=0.003) . Of infants whoreceived probiotic-supplemented formula, B. lactis was detected in80% of those delivered by Caesarean section and in 3 8% of thosedelivered vaginally, at the 1-month mark. In infants delivered byCaesarean section, the mean stool bifidobacteria level at 1 monthwas significantly higher in the probiotic-supplemented groupcompared to that of the non-supplemented group (P=0.021) .Conclusion Early bifidobacteria supplementation of infants,particularly those delivered by Caesarean section, is associatedwith higher levels of stool bifidobacteria. Anthropometric datasuggests beneficial effect s of bifidobacteria supplementationon infant growth, though most are not statistically significant.