. Wulandari
Program studi Farmasi FKIK, UIN Syarif Hidayatullah Jakarta

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Addition of conjugated linoleic acid in whole milk improves lipid profile in high fat diet induced hypercholesterolemia of rats Farmawati, Arta; Kusuma, Rio Jati; Iswara, Bayu Sigha; Wulandari, .; Utami, Kurniati Dwi; Kandarina, Istiti
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 48, No 4 (2016)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (449.571 KB) | DOI: 10.19106/JMedSci004804201601

Abstract

Conjugated linoleic acid (CLA) is an isomer of linoleic acid that has been shown to havemany beneficial effects in prevention of atherosclerosis, hypertension, cardiovasculardiseases and improve immune function. Although majority of CLA in the diet are derivedfrom dairy product such as milk, however, the content of CLA in milk is affected by cow’sdiet. The aim of this study was to investigate the beneficial effect of CLA supplementationin milk for improving lipid profile in high fat diet of rats. Twenty four male Sprague Dawleyrats aged 8 weeks were given high fat diet for 3 weeks to induce hypercholesterolemia.Six rats were maintained in standard diet as control. Rats then were divided into 4 groupsi.e. normal control, negative control, high fat diet+CLA 0.5%, high fat diet + CLA 0.5%supplemented skim milk, and high fat diet + CLA 0.5% supplemented whole milk. Bloodsample was drawn after high fat diet induced hypercholesterolemia and after 4 weeksof treatment for total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDLcholesterol), and high density lipoprotein cholesterol (HDL cholesterol) analysis. Bodyweight was measured each week. Results showed that body weight was significantlyincrease in all groups received high fat diet (p<0.05). There was no significant differencein body weight between treatment group (p>0.05). Total cholesterol, triglyceride, andLDL cholesterol was significantly decrease in whole milk followed by significant increasein HDL cholesterol level. Skim milk supplemented with CLA had only modest effect ontriglyceride and HDL cholesterol level. In conclusion, CLA supplementation in whole milkimproves lipid profile in high fat diet.
Model Probabilistik Fuzzy Goal Programming Berdistribusi Pareto dengan Urutan Prioritas pada Permasalahan Produksi Kue Susanti, Eka; Dwipurwani, Oki; Sitepu, Robinson; Wulandari, .; Natasia, Liani
Jurnal Matematika Vol 8 No 2 (2018)
Publisher : Mathematics Department, Faculty of Mathematics and Natural Sciences, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (71.575 KB) | DOI: 10.24843/JMAT.2018.v08.i02.p101

Abstract

Yulis’s home industry is one of the Small and Medium Bussiness (UKM) on Palembang city. Yulis’s home industry produces bolu kukus, kue lapis, kue pare, kumbu kacang, srikaya, and wajik. Most of cakes that will be produced by Yuli is still based on the cake sale on the last day, so that the profit is still not optimal condition. This research aims to create preemptive priority additive approach to Fuzzy Goal Programming Probabilistic (PFGP) model with Pareto distribution for maximize profits, minimize the production of perishable cake, and maximize best sellers cake. The &nbsp;results are obtained maximum profit is Rp. 8.488.569 on a week , the amount of perishable cake is 1,295 pieces on a week, and optimal production for best seller cake as much as 8,489 pieces on a week.