I.G.N. Wila Wirya
Department of Child Health, Faculty of Medicine, University of Indonesia

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A STUDY ON THE EFFECTS ADMINISTRATION OF ONE DOSE OF 300.000 I.U. ORAL VITAMIN A AND DEWORMING FOR PREVENTION AND TREATMENT OF VITAMIN A DEFICIENCY Samsudin, Samsudin; Karyadi, Darwin; Wirya, I.G.N. Wila; Susanto, Ig. Joko; Sudibyo, Supardi; Sutedjo, Hasnah; Husaini, Yayah
Buletin Penelitian Kesehatan Vol 3, No 1 Mar (1975)
Publisher : Buletin Penelitian Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/596

Abstract

Suatu penyelidikan tentang pencegahan dan pengobatan defisiensi citamin A pada anak-anak prasekolah telah dikerjakan didesa Tegal dan Iwul, Bogor dengan memberikan preparat vitamin A oral dosis tinggi. Preparat tersebut mengandung emulsi retinyl-palminate 300.000 I.U. yang dicampur dengan 100 I.U. citamin E (tocopheryl acetate). Dua golongan anak yaitu 100 tanpa dan 75 dengan xerophthalmia dipergunakan untuk studi tersebut. Mereka dibagi lagi dalam 4 kelompok. Kelompok pertama diberikan hanya vitamin A oral. Kelompok kedua diberikan obat cacing (deworming) terlebih dahulu sebelum diberikan vitamin A oral, dengan combantrin (pyrantel pamoate) single dose 10 mg/kg. berat badan. Kelompok ketiga diberi obat cacing dan placebo dan kelompok keempat hanya diberi placebo. Ternyata pada pemeriksaan setelah 6 dan 12 bulan kemudian semua anak tanpa xerophthalmia tetap terlindung dari xeropthalmia setelah diberikan vitamin A baik dengan atau tanpa deworming terlebih dahulu. Sedangkan 5-8 persen anak dengan xerophthalmia tidak dapat disembuhkan. Obat ca­cing tidak jelas menunjukkan pengaruhnya untuk memperbaiki penggunaan oral vitamin A, tetapi obat cacing dan vitamin A oral tersebut menunjukkan pengaruh baik terhadap keadaan gizi. Sedangkan terhadap kejadian penyakit, pengaruhnya tidak begitu jelas.
C3 and C4 Complements in Glomerular Disorders in Children Alatas, H.; Wirya, I.G.N. Wila; Tambunan, T.
Paediatrica Indonesiana Vol 18 No 3-4 (1978): March 1978
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (505.809 KB) | DOI: 10.14238/pi18.3-4.1978.75-82

Abstract

Seventy children who were hospitalized for kidney diseases in the Nephrological ward Department of Child Health, University of Indonesia, Jakarta were used in this study. Thirty seven patients sufferfng from acute poststreptococcal Glomerulonephritis (A.G.N.), 3 patients with Membranoproliferative Glomerulonephritis (M.P.G.N.) and 30 patients with Nephrotic Syndrome due to other causes were examined for complement concentration. A total of 80 samples were examined for C3 and 25 samples for C4 concentration using the immunediffusion plates. Almost all patients with A.G.N. and M.P.G.N. showed depression of C3. C4 concentration was normal except in 2 patients, 1 with A.G.N. and the other With M.P.G.N. This suggest activation of complement at the C3 level by the alternating pathway in most of the patients. C3 concentration in A.G.N. patients returned to normal after 8-10 weeks. In MPGN the depression was persistent in 2 patients, while in 1 patient it returned to normal level after 3 months of Immunosuppressive treatment.
Effect of Low Lactose Milk Eiwit Melk (E.M.) on Protein Calorie Malnutrition Suharjono, Suharjono; Wirya, I.G.N. Wila; Samsudin, Samsudin; Sunoto, Sunoto; Sulaiman, Z.; Sutedjo, Sutedjo
Paediatrica Indonesiana Vol 15 No 9-10 (1975): September 1975
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (380.276 KB) | DOI: 10.14238/pi15.9-10.1975.255-61

Abstract

During 1½ years, from January 1972 until July 1973, 55 P.C.M. children hospitalised in the Department of Child Health, Medical School, University of Indonesia/Dr. Tjipto Mangunkusumo General Hospital, were involved to this study. Self-prepared "Eiwit Melk (E.M.)" containing protein 2.7%, carbohydrate (lactose) 1.4%, fat 2.2% and calories 600, was used. Thirty children were treated with E.M. and 25 children as controlled, i.e. treated with E.M. + lactose 3.4% (E.M.L.). The results of the clinical trial as expressed with the increase of body weight, were excellent in 85.7% and good in 14.3%, whereas the results in the controlled group were excellent in only 9.1%, good in 36.4% and poor in 54.5%. From these excellent results, low lactose milk formula might be recommended in treating children with P.C.M.
Renogram in Children with Nephrotic Syndrome Wirya, I.G.N. Wila; Alatas, H.; Tambunan, T.; Sadeli, R.; Budiman, S.; Wijaya, E.
Paediatrica Indonesiana Vol 18 No 1-2 (1978): January 1978
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (546.338 KB) | DOI: 10.14238/pi18.1-2.1978.31-9

Abstract

Fifty children with nephrotic syndrome, aged 3 to 13 years, were studied for renogram patterns. Twenty-one cases had normal renograms; one case with bilateral and one with unilateral renal function. Seven cases showed bilateral renal impairment in both secretion and excretion phases. Impairment of excretion phase was found in 12 cases bilaterally and 8 unilaterally. None of them showed abnormality in the secretion phase alone. Eighteen out of 29 cases with abnormal renograms were studied further in remission states. The second renogram of these cases showed improvement to normal in 13 cases, two other cases still had impairment in the secretion and excretion phases, and the remaining 3 cases showed only impairment in the excretion phase. Ten healthy children as control had normal renograms. The correlation of clinical/laboratory findings and abnormal renograms patterns was discussed. Further studies on the use and limitation of the renograms in nephrotic syndrome in children are needed.
Bilateral Hydronephrosis with Recurrent Infections Wirya, I.G.N. Wila; Hariarti, Hariarti
Paediatrica Indonesiana Vol 19 No 3-4 (1979): March 1979
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (506.993 KB) | DOI: 10.14238/pi19.3-4.1979.111-6

Abstract

A case of bilateral hydronephrosis due to a congenital hereditary anomaly was reported. The operation was performed to remove the right kidney and ureter. Correction of the obstruction in the left ureter resulted in the better functioning of the left kidney, although we cannot be sure in the long run.