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DIRECTION OF HEPATITIS SUPPORTED RESEARCH AT NAMRU-2 Corwin, Andrew L.; Putri, Maidy P.; Graham, Robert Ross; Suprapto, Widodo; Lubis, I.; Wiharta, Adnan S.; P., Purnamawati S.; G., Djajadiman; Sulaiman, H. A.
Buletin Penelitian Kesehatan Vol 23, No 3 Sept (1995)
Publisher : Buletin Penelitian Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/237

Abstract

Titik berat penelitian hepatitis di NAMRU-2 pada saat ini adalah: I) penelitian binatang untuk mengetahui populasi reservoar HEV; 2) penggunaan model hewan untuk lebih diketahuinya transmisi HEV pada populasi reservoar yang dicurigai; 3) diketahuinya akurasi alat diagnostik yang digunakan (untuk semua marker); 4) diketahuinya lama pengeluaran virus hepatitis E pada kotoran manusia yang menderita hepatitis akut maupun dari model hewan; 5) diketahuinya insidens hepatitis E akut melalui pencarian kasus dengan menggunakan metode penelitian lapangan di masyarakat; dan 6) serokonversi infeksi hepatitis E pada anak-anak. Hubungan erat dengan berbagai universitas dan instansi pemerintah yang terkait dengan penanganan kasus-kasus hepatitis, telah dan masih menjadi bagian penting bagi suksesnya penelitian hepatitis di NAMRU-2. Hasil yang dicapai berdasarkan program penelitian di atas antara lain: 1) seminar hepatitis E di Kalimantan Barat; 2) tersedianya kemampuan diagnostik pada laboratorium setempat; 3) pembinaan peneliti di Indonesia dan Asia Tenggara dalam hal epidemiologi; serta 4) alih teknologi dalam pelaksanaan penelitian yang dapat melibatkan minat para peneliti pada penyakit hepatitis di Indonesia.
Diarrhoeal Disease of Children in Indonesia Sunoto, Sunoto; Wiharta, Adnan S.; Saroso, J. Sulianti
Paediatrica Indonesiana Vol 18 No 11-12 (1978): November 1978
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1248.932 KB) | DOI: 10.14238/pi18.11-12.1978.332-58

Abstract

Diarrhoeal disease in infants and children up till now is still becoming a major problem with its high morbidity and mortality. There are too many factors which can play a role in causing this disease. But by giving Oral-glucose electrolyte Solution as soon as possible the case fatality rate can be reduced as low as possible. Whereas decreasing the morbidity still needs a very long time, since it has very multi-complex factors i.e. socio-economic condition, environmental and personal hygiene and sanitation, life style of people, belief, etc. The study on epidemiology, the influence of improvement of environmental sanitation and socio-anthropology is still very few, besides there is no satisfactory vaccin produced to prevent this disease. Meanwhile the worse of the case is that there is a tendency of decreasing breast-feeding in the big cities and to substiotute it with bottle-feeding.
The "Rose System" in Overcoming the Second Cholera Outbreak in Jakarta from May 25-30, 1976 Wiharta, Adnan S.; Sutejo, R.
Paediatrica Indonesiana Vol 18 No 1-2 (1978): January 1978
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.236 KB) | DOI: 10.14238/pi18.1-2.1978.6-10

Abstract

1.a. During a short cholena outbreak in Jakarta frnom 25th May to 30th May, 1976, 70 children aged from 6 months to 13 years suffering from acute diarrhoea and dehydration, shock or pre-shock were admitted to the provisional Rehydnation Cetntre in the outpatient section of the Departmernt of Child Heatth, University of Indonesia/Dr. Cipto Mangunkusumo General Hospital, Jakarta.b. None died.c. 71.9% of the stool specimens from 32 patients revealed Vibrio Cholera El Tor Ogawa type.2. The methodology used was the so-called "ROSE" system :a. Rehydration with ringer's lactate solution.b. Oralyte in boiled water given ad libi┬Ětum.c. Oralyte solution and intravenous solution given Simultaneously.d. Education to the parents on the importance of giving oralyte solution ad libitum.3. This paper dealt with the second success of the Rose system in facing a cholera outbreak.
HBsAg in Cord Blood Qf Newborns of HBsAg-Positive Mothers Wiharta, Adnan S.; Setiadi, Evi; Noer, H. M. Sjaifullah; Rachimhadhi, Triyatmo; Rasad, Asri
Paediatrica Indonesiana Vol 34 No 5-6 (1994): May 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.132 KB) | DOI: 10.14238/pi34.5-6.1994.125-8

Abstract

Vertical transmission of hepatitis B infection that may occur during pregnancy at delivery-, in infancy, and early childhood has an important role in the development of chronic hepatitis B. Intrauterine infection is suspected to occur when hepatitis B viruses cross the placenta into fetal circulation due to failure of placental tissue function. In Cipto Mangunkusumo Hospital, Jakarta, 98 (6.4%) of 1536 pregnant mothers obseiVed during 3 years (1987 -1990) showed positive HBsAg. Six (8.3%) of 60 babies of born to HBsAg positive mothers showed positive HBsAg in their cord blood, but this disappeared after one month. All babies born to HBsAg positive mothers were vaccinated on months 0, 1, 2, and 12. HBsAg in cord blood might not play an important role in vertical transmission.
Breast milk and Bottle Milk in relation with gastroenteritis Rumondang, Rumondang; Suharyono, Suharyono; Budiarso, Aswitha; Utomo, Mugijo K.; Wiharta, Adnan S.
Paediatrica Indonesiana Vol 19 No 9-10 (1979): September 1979
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.8 KB) | DOI: 10.14238/pi19.9-10.1979.226-30

Abstract

A study on 1043 children aged 3 days to 2 years hospitalized in the Department of Child Health, from 1 January to 31 December 1976, was made fo find out the relation between breast milk and bottle milk with gastroenteritis, especially concerning bacterial, fungal infection and fat malabsorption.