Senny Widyaningsih
Jurusan Kimia, Fakultas MIPA, Universitas Jenderal Soedirman. Jl. Dr. Suparno, Purwokerto, Jawa Tengah, 53123

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Formulasi Deterjen Berbahan Aktif Etil Ester Sulfonat dari Minyak Biji Ketapang (Terminalia cattapa) dengan Penambahan Enzim Papain Chasani, Moch.; -, Purwati; Widyaningsih, Senny; Larasati, Bina
Jurnal Sains dan Teknologi Kimia Vol 4, No 2 (2013): Jurnal Sains dan Teknologi Kimia
Publisher : Program Studi Kimia Jurusan Pendidikan Kimia FPMIPA UPI

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Abstract

Enzim papain merupakan salah satu enzim protease yang dapat dijadikan sebagai additive pada formulasi deterjen. Protease dalam deterjen secara spesifik membantu menghilangkan protein yang menodai pakaian. Penelitian ini bertujuan untuk mengkaji pengaruh penambahan enzim papain terhadap karakteristik deterjen berbahan aktif etil ester sulfonat dari minyak biji ketapang (Terminalia cattapa).    Karakteristik  deterjen  yang  ditentukan  meliputi:  Bahan  tidak  larut dalam  air,  Stabilitas  emulsi,  dan  Stabilitas  busa.  Hasil  penelitian  merupakan bahan tidak larut dalam air dari deterjen   tanpa papain dan deterjen dengan konsentrasi papain  1, 3, 5, 7, dan 9% (b/b)  berturut-turut sebesar 6; 6; 5; 4; 5, dan 4%. Stabilitas emulsi deterjen tanpa papain dan deterjen dengan konsentrasi papain 1, 3, 5, 7, dan 9% (b/b) berturut-turut adalah 93,05; 90,20; 90,70; 94,55; 94,60 dan 96,05% dan Stabilitas busa deterjen tanpa penambahan papain dan deterjen enzimatik dengan penambahan konsentrasi papain 1, 3, 5, 7, dan 9% (b/b) berturut-turut adalah 83,33; 70,00; 78,33; 78,59; 73,64, dan 77,50%.  Penambahan enzim papain pada deterjen hasil formulasi menggunakan surfaktan etil ester sulfonat dari minyak biji ketapang berpengaruh terhadap karakteristik deterjen yang meliputi bahan tidak larut dalam air, stabilitas emulsi, dan stabilitas busaKata kunci: Deterjen, Terminalia cattapa, papain.
MEMBRAN KOMPOSIT CA-PS PEMISAH LIMBAH BATIK (RHODAMINE B) DENGAN “DEAD-END” MEMBRANE REACTOR Ayusnika, Rizka; Gunawan, Hendra; Ismawati, Ismawati; Nugroho, Muhammad Wisnu; Apriliani, Rizki Nur; Widyaningsih, Senny
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 11 No. 02 Desember 2014
Publisher : Fakultas Farmasi, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pji.v11i2.838

Abstract

ABSTRAK Perkembangan teknologi membran sebagai unit pengolah limbah saat ini sangat pesat dan banyak digunakan dalam proses pemisahan, seperti limbah batik (rhodaminee B). Tujuan dari penelitian ini membuat membran komposit selulosa asetat dari limbah kulit pisang dengan polistirena dan mengetahui aplikasinya dalam proses pemisahan limbah batik (rhodaminee B). Metode pembuatan membran ini adalah inversi fasa, yaitu proses sebuah polimer diubah secara terkendali dari fasa cair ke fasa padat. Penelitian ini diawali dengan tahap pembuatan selulosa (nata de banana skin) melalui proses fermentasi oleh bakteri Acetobacter xylinum. Tahap kedua adalah proses asetilasi selulosa menjadi selulosa asetat. Tahap berikutnya adalah pembuatan membran komposit CA-PS untuk kemudian dilakukan proses pemisahan limbah batik (rhodaminee B) dengan aplikasi pada alat “dead-end”. Karakterisasi membran komposit CA-PS telah dilakukan dengan penentuan fluks, koefisien rejeksi, uji kuat tarik dan regangan, serta morfologi dan ukuran pori membran menggunakan SEM. Hasil pengukuran diperoleh nilai fluks air dan sampel berturut-turut sebesar 4,3889 L/(m2.jam) dan 1,4629 L/(m2.jam), nilai koefisien rejeksi sampel (rhodaminee B) sebesar 16%, nilai uji tarik sebesar 10,38 MPa, dan ukuran rerata pori-pori sebesar 5,114 μm. Kata kunci: selulosa asetat, nata, rhodamine B, CA-PS, dead-end. ABSTRACT The development of membrane technology as a waste treatment unit is currently very rapidly and widely used in the separation process, such as batik waste (rhodamine B). The purpose of this research is to make a composite membrane of cellulose acetate derived from banana peel fermentation with polystyrene and determine its application in waste separation process of batik waste (rhodamine B). The method of making the membrane is phase inversion, i.e the process of a polymer modified in a controlled manner from liquid phase to solid phase. This research begins with manufacturing of cellulose (nata de banana skin) through fermentation by Acetobacter xylinum. The second stage is acetylation process of cellulose into cellulose acetate. The next stage is manufacturing composite membranes CA-PS and its application in batik waste (rhodamine B) separation process with the application on "dead-end" reactor. Characterization of CA-PS composite membrane has been done with the determination of flux, rejection coefficient, tensile strength and strain as well as the morphology and pore size of the membrane using SEM. The measurement results obtained the water flux are of 4.3889 L / (m2.h) and sample flux are 1.4629 L / (m2.h), rejection coefficient are 16%, tensile test are 10.38 MPa, and the average pore size are 5.114 µm. Key words: cellulose acetate, nata, rhodamine B, CA-PS, dead-end.
PEMANFAATAN MEMBRAN NATA DE COCO SEBAGAI MEDIA FILTRASI UNTUK REKOVERIMINYAK JELANTAH Widyaningsih, Senny; Purwati, Purwati
Molekul Vol 8, No 1 (2013)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.05 KB) | DOI: 10.20884/1.jm.2013.8.1.122

Abstract

Peningkatan kualitas minyak jelantah telah dilakukan dengan metode filtrasi menggunakan membran selulosa bakterial yang terbuat dari nata de coco. Pembuatan membran nata de coco dilakukan dengan cara memurnikannata de coco hasil proses fermentasi bakteri Acetobacter xylinum. Karakterisasi membran meliputi berat jenis, nilai fluks, dan koefisien rejeksi. Proses filtrasi minyak jelantah menggunakan tekanan sebesar 4 kgf/cm2 dengan metode dead-end. Hasil penelitian menunjukkan bahwa karakterisasi membran nata de coco memiliki berat jenis sebesar 0,6314 g/cm3, nilai fluks air sebesar 104,021 L/m2.jam, fluks minyak sebesar 1,004 L/m2.jam dan fluks Dekstran T-500 sebesar 52,208 L/m2.jam. Nilai rejeksi membran sebesar 15,11%. Peningkatan kualitas minyak jelantah dibanding sebelum rekoveri dapat dilihat dari penurunan angka asam sebesar 54,95%, kadar air sebesar 93,22%, serta peningkatan angka penyabunan sebesar 29,09% dan angka iod sebesar 8,14%.
BIODEGRADASI POLIETILENA MENGGUNAKAN BAKTERI DARI TPA (TEMPAT PEMBUANGAN AKHIR) GUNUNG TUGEL KABUPATEN BANYUMAS Zusfahair, Zusfahair; Lestari, Puji; Riana Ningsih, Dian; Widyaningsih, Senny
Molekul Vol 2, No 2 (2007)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.89 KB) | DOI: 10.20884/1.jm.2007.2.2.39

Abstract

Plastic has high potency to become material that much threats human living in this earth, because made from chemical which cannot degraded by microbes in environment. The successful production and marketing of biodegradable plastics will help alleviate the problem of environmental pollution. One of biodegradable plastic that used in our live is polyethylene. This research reveals that local microbes capable to degrading of polyethylene. Biodegradation test was carried out by using bacteria in soil which was obtained from Gunung Tugel disposal center, Banyumas regency. Kind of polyethylene is LDPE (Low Density Polyethylene) which was obtained from Setiakawan Plastic Factory, Kalibogor, Purwokerto formed to thin film. Characterization of the polyethylene used weight loss percentage method, melting point determination and FTIR. Soil bacteria isolated from Gunung Tugel disposal center, Banyumas regency, obtained 5 single colonies, which coded GT. Bacteria isolate which have highest activity in degrading polyethylene was GT 3, with increasing the time of incubation. Weight loss percentage up to 2.33% in 1 month. Melting point of polyethylene after biodegradation was decreased that initially 210-220 °C into 210-213 °C. FTIR spectrophotometer result of polyethylene after biodegradation showed intensity for methylene and methyl cluster was decreased.
PEMODELAN SENYAWA TURUNAN ASAM KARBAMAT SEBAGAI SENYAWA ANTIKANKER MENGGUNAKAN METODE SEMIEMPIRIS AM1 Widyaningsih, Senny; Purwati, Purwati; Riyadi, Riyadi
Molekul Vol 2, No 2 (2007)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (227.998 KB) | DOI: 10.20884/1.jm.2007.2.2.34

Abstract

4-N-carbamic acid-4?-dimetylpipodopylotoxin and its derivatives are compounds which are synthesized from etoposide (VP 16). These compounds are used as anticancer medicine because they inhibit DNA topoisomerase II enzyme. The enzyme participates in controlling breaking process of DNA double helix bounding in cancer cell. It makes cancer growing cease and dies because cell can not replicate. However, the compound insoluble in water, make a medicine resistant, inhibit metabolism system and poison. It needs to design a modification of new compounds from carbamic acid derivatives which have higher activity. Structure modification was done using Quantitative Structure Activity Relationship (QSAR) which was a computational chemistry application in medicine design process. This research used semiempiris AM1 method to determine the best QSAR equation based on multilinear regression analysize, with log 1/IC50 as dependent variable and independent variables were atomic net charge of qN29, qC30, qO31, qO32, dipole moment, n-octanol-water coefficient partition (Log P), and polarity. The best QSAR equation in this research was : Log 1/IC50 = 4.871 + 12.738 qN29 + 33.183 qC30 + 28.015 qO31 ? 3.6 x 10-2 polarity, with N = 13, r =0.907, SE = 0.13025, Fcount/Ftable = 1.901, PRESS = 0.1357. Based on the best QSAR equation, the prediction compounds were 1, 2, 3, 8, and 22 with each IC50 theoretical value were 0.032, 0.034, 0.036, and 0.098 µM.
AKTIVITAS ANTIBAKTERI MINYAK ATSIRI DAUN PALA DARI BANYUMAS TERHADAP Staphylococcus aureus DAN Escherichia coli SERTA IDENTIFIKASI SENYAWA PENYUSUNNYA Rastuti, Undri; Widyaningsih, Senny; Kartika, Dwi; Riana Ningsih, Dian
Molekul Vol 8, No 2 (2013)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (456.384 KB) | DOI: 10.20884/1.jm.2013.8.2.142

Abstract

Staphylococcus aureus dan Escherichia coli adalah bakteri yang dapat menyebabkan infeksi. Umumnya masyarakat dalam mengobati penyakit infeksi terhadap bakteri sering menggunakan antibiotik, namun apabila digunakan secara berlebihan dan kurang terarah dapat mengakibatkan terjadinya resistensi. Untuk mengatasinya diperlukan pencarian bahan alami sebagai alternatif pengobatan, salah satunya yaitu minyak atsiri daun pala. Penelitian inibertujuan untuk mengetahui aktivitas antibakteri minyak atsiri daun pala dari Banyumas terhadap S. aereus dan E. coli serta mengidentifikasi senyawa penyusunnya. Minyak atsiri dari serbuk daun pala kering diisolasi menggunakan metode destilasi air. Minyak atsiri yang diperoleh diuji sifat fisik dan dilakukan identifikasi senyawa penyusunnya menggunakan GC-MS. Pengujian aktivitas antibakteri dilakukan dengan menggunakan metode difusi untuk mengetahui Konsentrasi Hambat Tumbuh Minimum (KHTM) terhadap S. aereus  dan E. coli. Rendemen minyak atsiri daun pala yang diperoleh sebesar 1,34%. Minyak atsiri ini berwarna kuning pucat, berbau khas minyak pala dengan indeks bias sebesar 1,4779 dan bobot jenis sebesar 0,8862 g/cm3. Minyak atsiri daun pala diketahui memiliki 33 komponen kimia dan 5 komponen kimia terbesarnya adalah sabinene, terpinene-4-ol, ?-pinene, ?-pinene, and ?-phellandrene. Minyak atsiri daun pala terbukti memiliki aktivitas antibakteri terhadap S. aureus dengan KHTM pada konsentrasi minyak atsiri 3,125%  menghasilkan zona hambat sebesar 16,81 mm dan terhadap E. coli dengan KHTM pada konsentrasi minyak atsiri 1% menghasilkan zona hambat sebesar 0,54 mm.
KARAKTERISASI ABU TERBANG PLTU CILACAP UNTUK MENURUNKAN KESADAHAN AIR DI DESA DARMAKRADENAN KECAMATAN AJIBARANG KABUPATEN BANYUMAS Widyaningsih, Senny; Setiawan, Ely; Setyaningtyas, Tien
Molekul Vol 6, No 1 (2011)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.006 KB) | DOI: 10.20884/1.jm.2011.6.1.89

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Fly ash is an ash with smooth granular shape and black grey color. It is a waste material produced from the burning of coal. The contain of fly ash especially is silica and alumina that it can be used as adsorbent. As adsorbent, fly ash as used to decrease water hardness at Darmakradenan Village, Ajibarang District. The result showed that the porosity of fly ash was 13.6056%, the water content was 0.055%, adsorption capacity of iodium was 216.8975 mg/g, and adsorption capacity of methylen blue was 0,3891 mg/g. Fly ash could decrease total water hardness. The adsorption rise when contact time was added. Adsorption reached equilibrium at contact time 120 minutes with decreasion percentage 63.6363%.
KECEPATAN ADUK DAN WAKTU KONTAK OPTIMUM PEMBUATAN BIODIESEL DARI MINYAK JELANTAH Kartika, Dwi; Vaulina, Eva; Widyaningsih, Senny; Chasani, Moch.
Molekul Vol 5, No 1 (2010)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (241.422 KB) | DOI: 10.20884/1.jm.2010.5.1.74

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Synthesis of biodiesel from waste cooking oil using activated natural zeolite catalyst has been done. Activation of the natural zeolite was done by refluxing with HCl 6M for 30 min, calcining and oxydizing at 500°C for 2 hours, consecutively. The variation of stirring speed were 350, 700, 1100 and 1200 rpm. The variation of reaction time were varied from 15, 30, 45, 60, and 120 min. The conversion of biodiesel was determined by 1H NMR spectrometer. The results showed that the optimum condition of biodiesel synthesis using esterification process were reached at 700 rpm and 15 minutes, which gave biodiesel conversion of 100%.
PEMANFAATAN BAKTERI HASIL ISOLASI DARI TPA (TEMPAT PEMBUANGAN AKHIR) GUNUNG TUGEL KABUPATEN BANYUMAS SEBAGAI AGEN BIODEGRADASI POLIMER POLIEUGENOL Lestari, Puji; Zusfahair, Zusfahair; Riana Ningsih, Dian; Widyaningsih, Senny
Molekul Vol 3, No 2 (2008)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.797 KB) | DOI: 10.20884/1.jm.2008.3.2.48

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A number of microbes are known to have ability to degrade synthetic polymers such as polyeugenol. This research was attempted to know the genus of bacterium that isolated from Gunung Tugel garbage dumping land which is able to degrade polyeugenol and to characterize polyeugenol before and after biodegradation process using this bacterium. Pure eugenol was polymerized into polyeugenol by adding concentrated sulphate acid, and then formed become a thin film. Bacterium which is isolated from Gunung Tugel garbage dumping land was suggested asAcinetobacter sp. Polyeugenol thin film was incubated with this bacterium with various incubation times 5, 10, 15, 20, 25, 30 and 60 days. Thin film then was characterized including melting point value, percentage of weight loss, molecular weight, and the function groups by FTIR. Melting point of initial polyeugenol was 135-137oC and after biodegradation was 98-100oC. Percentage average of loss weight was 0.5637% (b/v). Molecular weight of polyeugenol before degradation was 61.472.882,91 g/mole and after biodegradation was 5,542,915.464 g/mole. FTIR spectrum percentage of transmittance of polyeugenol after biodegradation was decreased.
PEMBUATAN SELULOSA ASETAT DARI PULP KENAF (Hibiscus cannabinus) Widyaningsih, Senny; Radiman, Cynthia Linaya
Molekul Vol 2, No 1 (2007)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.378 KB) | DOI: 10.20884/1.jm.2007.2.1.181

Abstract

Cellulose acetate (CA) is one of polymer which is usually used in industry. Kenaf (Hibiscus cannabinus) pulp is one of non wood cellulose sources which can be used for producing CA. CA was produced in three step i.e. initial, acetylation, and hydrolysis. The characterization of CA kenaf had been conducted with analyzing function groups and determining relative molecule mass, acetyl content, and structure of CA. The result of infrared spectroscopy analyze showed that specific peak of acetyl group at 1237.4 cm-1 with acetyl content 40.40% and the relative molecule mass of CA was 1.15.104 with amorf structure.