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PENURUNAN ANGKA PEROKSIDA MINYAK KELAPA TRADISIONAL DENGAN ADSORBEN ARANG SEKAM PADI IR 64 YANG DIAKTIFKAN DENGAN KALIUM HIDROKSIDA

Journal of Chemistry Vol. 2, No. 1 Januari 2008
Publisher : Journal of Chemistry

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Abstract

Research on IR64 rice shell ash activation with KOH was carried out. Then, this activated ash known asadsorbent was applied to absorb H2O2 solution. This adsorbent was then applied to absorb peroxide number oftraditional coconut oil.The research includes activation of rice ash with 5%, 10%, and 15% KOH, followed by determination ofrate and isotherm adsorption towards H2O2. Finally, the ash was applied to absorb traditional coconut oil, in order todecrease peroxide number of the oil.Research results indicated that, adsorption rate of the ash with KOH activation is higher than without KOHactivation. Adsorption isotherm patern of the ash with and without activation is following Langmuir adsorption. Riceshell ash activated with 15% KOH can increased adsorption capacity of H2O2 about 297.16 mg/g, whereas withoutactivation the adsortion capacity is about 271.66 mg/g. Activated ash with 15% KOH was the applicated to decreaseperoxide number of traditional coconut oil. In this study, we obtain that the ash can decreased peroxide number until84.4%.

PEMBERIAN MINYAK IKAN LEMURU (Sardinella longiceps) SEBAGAI ANTI DISLIPIDEMIA MELALUI PENINGKATAN HDL PADA TIKUS WISTAR

Journal of Chemistry Vol. 5, No. 2 Juli 2011
Publisher : Journal of Chemistry

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Abstract

Changes in consumption behaviour to instant food can cause various health problems, such as obesity, dislipidemia, and atheroschlerosis. A study was conducted to investigate sardinella longiceps oil as anti dislipidemia through increasing HDL-C levels.This is a true experimental with randomized pre and posttest control group designs, emplyoying 50 Wistar rats grouped into five groups, i.e. control group (0% fish oil), treatment 1 group (10% fish oil), treatment 2 group (15% fish oil), treatment 3 group (20% fish oil), and treatment 4 group (25% sardinella longiceps oil). This research observed that intake of 20% sardinella longiceps oil resulted in the higest significant increase of HDL-C of 22.78 % (from 55.97 ±1.25 to 68.72 ± 6.25 mg/dL) for dislipidemia study. Therefore, it can be concluded that intake of sardinella longiceps oil in Wistar rat acts as anti dislipidemia by increasing the HDL-C levels. Further research is required to determine whether the application of sardinella longiceps on human will result in a simillar way, as anti inflammation and anti dislipidemia.

Penentuan Rute Terpendek Menggunakan Variasi Fungsi Heuristik Algoritme A* Pada Mobile Devices

Jurnal Ilmiah Ilmu Komputer Vol 8, No 2 (2010): Jurnal Ilmiah Ilmu Komputer
Publisher : Jurnal Ilmiah Ilmu Komputer

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Abstract

GPS (Global Positioning System) is a technology that can help people in reaching the destination place in a fastest time and shortest route. Many mobile devices, some of them are cellular phones, have GPS facility. But this type of cellular phone is still expensive. This research intended to develop a shortest path searching application for mobile devices using variation of heuristic function A* algorithm, such as Manhattan, Euclidian, and Square of Euclidian. In addition, we intended to compare the execution time of these heuristic functions in finding shortest route. The data used in the experiment was Bogor Agricultural University map that obtained from Bogor Agricultural University Facility and Property Directorate. The map ought to modified to grid form to be appeared in cellular phone screen. The matrix that used to grid had a size of 15 x 12 and values of 0, 1, 5, 6, 7, 8, 9, and 10. Value of 0 expressed walkable route, and value of 1 expressed unwalkable route. The rest values expressed the map facilities, like faculties and rectorate buildings. The experiments indicated that Square of Euclidian had faster execution time and less amount of checked nodes than other heuristic functions. The lack was that this algorithm did not always provide shortest route. Euclidian heuristic function had slower execution time and more amount of checked nodes than others, whereas Manhattan have faster execution time and less amount of checked node than Euclidian. Euclidian and Manhattan heuristic function always provide shortest route in finding destination.

Perbandingan Kualitas Layanan Wireless VOIP pada Codec G.711, G.723 dan G.729

Jurnal Ilmiah Ilmu Komputer Vol 8, No 1 (2010): Jurnal Ilmiah Ilmu Komputer
Publisher : Jurnal Ilmiah Ilmu Komputer

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Abstract

Voice over Internet Protocol (VoIP) is a technology that enable voice message transmission over  data network (internet protocol). Codec is algorithm or special computer program to reduce number of bytes. The usage of appropriate codec at implementation VoIP is one thing determining in attainment of quality VoIP communications. This research implement and analys the usage of codec G711, G723 and G729 at protocol H323 for VoIP service. Examination by through simulation using ns-2. Codec G723 has smaller delay value and jitter value  than codec G711 and G729. The result from simulation is codec G723 has smaller bit rate value, so more efficient for implementation at network that having not big bandwidth or network capacity. In communications process usage of codec G.723 will not encumber network.

Pengembangan SIJELITA sebagai Sistem Keamanan Perumahan berbasis SMS dan PSTN

Jurnal Ilmiah Ilmu Komputer Vol 6, No 2 (2008): Jurnal Ilmiah Ilmu Komputer
Publisher : Jurnal Ilmiah Ilmu Komputer

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Abstract

A housing security system based on computer technology have been develop. This system was develop considering a need for effectively security system to prevent crime action in housing. Beside that, a housing security system can also develop by adding announcement function to the house owner using SMS service. Announcement function can also give to the neighborhood  because they are the nearest outsider to take an action when crime activity happened. Announcement function to the neighbourhood can be develop using PSTN service. The purpose of this research is to develop an existing housing security system named SIJELITA (SIstem Jaminan kEamanan meLaluI Teknologi nirkAbel) by adding SMS and PSTN dial up features. Function of that features consecutively is to sending information to house owner through SMS service and neighborhood through PSTN’s public telephone service. Evaluation of system execute based on time of response needed to send SMS and do a dial up process to PSTN public telephone line with 425 Hz frequency of dial tone. SMS response time counted since detector which placed in door and window send a signal until SMS receive in the destination cell phone.  Dial up response time counted since detector which placed in door and window send a signal until the destination phone ring. Response  time and system testing was done 30 times in busy time in 10 days consecutively. From testing was done, the lowest average response time  for SMS and dial up consecutively was 9,33 second and 11,7 second. The highest response time for SMS and dial up was 10,285 second and 13,069 second. During testing, system can send SMS to the destination cell phone and do dial up process to the destination phone number. This thing shows that this system is quite rely on with 100% success in acceptance of data so it can be concluded this prototype can be recommended as an escort in implementing a housing security system.

EKSTRAK DAUN SIRSAK (Annona muricata L.) SEBAGAI ANTIOKSIDAN PADA PENURUNAN KADAR ASAM URAT TIKUS WISTAR

Journal of Chemistry Vol. 6, No. 2 Juli 2012
Publisher : Journal of Chemistry

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Abstract

Isolation and identification of anti-oxidant  active isolate from soursop leave (Annona muricata L.) was carried out in this study. Methanol was used to macerate an 158 gram sample. This crude extract showed 77,22% of inhibition ability to reduce oxidation of DPPH (difenil-picrylhydrazine) at the fifth minute and 85,42% at the sixtieth minute inhibition time. Petroleum benzene, chloroform, n-buthanol, and water were applied to separate it. N-buthanol extract has the highest anti-oxidant reduction percentage which was 91,10% of inhibition ability to reduce oxidation at the fifth minute and 97,90% at the sixtieth minute inhibition time. From this research, it was obtained that the best dose of n-buthanol fraction applied to decrease uric acid was 200 mg/Kg BW with a percentage decrease of 86,29% (p=0,001).n-buthanol  fraction was identified by gas chromatography-mass spectrometer. The active compounds observed were: benzofuran,2,3-dihidro; tetradecana;  3-ethoxy-1,4,4a,5,6,7,8,8a-octahydroisoquinoline;  2-cyclohexen-1-one, 4-hydroxy-3,5,6-trimethyl-4-(3-oxo-1-butenyl). In conclusion, soursop leave (Annona muricata L.) extract  was active for decreasing uric acid of rat tested. For future research, this method could be applied to human in decreasing uric acid concentration in blood.

IDENTIFIKASI SENYAWA AKTIF ANTIMAKAN BIJI SIRSAK (Annona muricata L.) TERHADAP ULAT KUBIS (Plutella xylostella)

Journal of Chemistry Vol. 8, No. 2 Juli 2014
Publisher : Journal of Chemistry

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Abstract

Identification of antifeedant active compounds from Soursop seeds (Annona muricata Linn) as natural pesticides against Plutella xylostella has been carried out. 1800 g Soursop seed powder  maceration was applied using methanol and n-hexane resulted in 46.42 g extract of methanol and 94.19 g extract of n-hexane. Viscous extract of methanol was diluted with the mixture of methanol:water (7:3), then evaporated until the entire methanol was removed, and after that it was partitioned with chloroform. The antifeedant activity of viscous extract of n-hexane, chloroform and water was tested which showed that the extract of n-hexane had highest activity compared to the others. Separation of 2 g viscous n-hexane extract with Coloumn Chromatography using Gel Silica 60 and n-hexane:aceton (4:1) as the mobile phase resulted in 5 fractions. The fractions were tested against Plutella xyllostella. The results showed that fraction C had the highest antifeedant activity. The isolate of fraction C was then identified using Gas Chromatography-Mass Spectrometry (GC-MS) based on the data base (DatabaseNISTO2.L and Databasewiley7n.1) suggested the active compounds were ethyl hexadecanoate ester and 11-octadecanoic acid.

UJI PEMANFAATAN DAUN SIRSAK (Annona muricata L.) DALAM MENGHAMBAT STRES OKSIDATIF PADA TIKUS WISTAR HIPERKOLESTEROLEMIA MELALUI PENINGKATAN AKTIVITAS SUPEROXIDE DISMUTASE

Journal of Chemistry Vol. 9, no. 1 Januari 2015
Publisher : Journal of Chemistry

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Abstract

Oxidative stress is an imbalance condition between free radicals in the body with the anti-oxidant. Superoxide dismutase (SOD) is one of the endogenous anti-oxidant that can neutralize the excess of Reactive Oxygen Species (ROS). The excess of ROS that caused by stres oksidative can also be neutralized with the help of exogenous anti-oxidants. A soursop plant (Annona muricata L.) has anti-oxidant activity, especially in the leaves. This study aims to determine the activity of the leaves of the soursop (Annona muricata L.) in inhibiting the oxidative stress that conducted on the object hypercholesterolemic rats wistar through increasing SOD activity using variations of the extract dose of 50 mg/kg BW; 100 mg/kg BW and 150 mg/kg BW. In this study the dose gives the best result in inhibiting the oxidative stress through an increase in SOD activity was dose of 150 mg/kg BW with percent inhibition of SOD at (81,42% ± 3.91) where the percent inhibition of SOD is directly proportional to the activity of SOD

PEMBERIAN EKSTRAK ETANOL BUAH BUNCIS (Phaseolus vulgaris L.) UNTUK MENURUNKAN KOLESTEROL TOTAL, Low Density Lipoprotein (LDL) DAN MENINGKATKAN High Density Lipoprotein (HDL) PADA TIKUS WISTAR DIET TINGGI LEMAK

Journal of Chemistry Vol. 10, no. 1 Januari 2016
Publisher : Journal of Chemistry

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Abstract

Excessive fat consumption can increase blood cholesterol level. Phytosterol composition in the plant can decrease blood cholesterol level. One of the plants that contain phytosterol is beans. This study was to prove the effect of antihypercholesterol the ethanol extract of the beans (Phaseolus vulgaris L.) with variety of doses of 50 mg/Kg BW; 100 mg/Kg BW and 150 mg/Kg BW in male Wistar rats with high fat level condition. Subjects of this study were 24 Wistar rats divided into 6 groups randomly with posttest control group study design. First group as negative control, second group as positive control, and the third (high cholesterol diet and ethanol extract in dose of 50 mg/kg,bw), fourth ( high cholesterol diet and ethanol extractin dose of 100 mg/kg,bw), fifth ( high cholesterol diet and ethanol extract in dose of 150 mg/kg,bw),  sixth (high cholesterol diet and simvastatin drug). The data was analyzed with ANOVA Tukey test. The result of this study shows total cholesterol levels decrease 23,88%; 30,14%; 35,82%. Cholesterol LDL levels decrease 38,09%; 52,38%; 61,35%. Cholesterol HDL levels increase 21,86%; 56,56%; 63,84%. Dose variant on this study giving the best result to decrease total cholesterol levels and LDL was 150 mg/Kg BW. Furthermore, 100 mg/Kg BW dose gave the best result to increase HDL cholesterol level. Based on the results it can be suggested that beans ethanol extract is able to decrease total cholesterol level, LDL and increase HDL cholesterol levels.  

PENTAMETHYLCARBOXYLATE RUTHENOCENE BASED ANTITUMOUR AGENT

BALI MEDICAL JOURNAL Vol 4, No 2 (2015)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Unlike iron ruthenium is not an essential element for life. However, the behavior of ruthenium compounds in biological systems and, in particular their use as antitumour agents has attracted much attention recently. This study aims to determine antitumour properties against human tumour cell line HeLa of pentamethylcarboxylate ruthenocene. Methods: This is an in vitro study by applying an experimental within post only control group design. Cisplatin, a clinical used medicine was applied for control. The human tumour cell line Hela was used for the test. The cells were cultured at 370C in 5% CO2/air in Roswell Park Memorial Institute Medium 1640 and seeded overnight in 96 well microtitre plates. The penthamethylcarboxylate ruthenocene was dissolved in 1,2 dimethoxy ethane and diluted with culture media. The plates were assays by measuring optical density in the range of 490-655 nm. The D37 values were then calculated. Results: The pentamethylcarboxylate ruthenocene compound tested was found to be more cytotoxic than cisplatin (with D37 = 422 nM compare to D37 = 705 nM for cisplatin). Conclusions: The compound tested, pentamethylcarboxylate ruthenocene was found more potent as an antitumor compare to cisplatin a clinical used antitumor for curing testicular carcinoma.