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Aktivitas Hepatoprotektif Ekstrak Etanol Daun Kucing-kucingan Acalypha indica L.) pada Tikus Putih (Rattus Novergicus) yang Diinduksi Parasetamol Armansyah TR, T; Sutriana, Amalia; Aliza, Dwinna; Vanda, Henni; rahmi, erdiansyah
Jurnal Ilmu-Ilmu Peternakan JIIP Volume XIII No. 6 Mei 2010
Publisher : Jurnal Ilmu-Ilmu Peternakan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (71.575 KB)

Abstract

The  research  has  been  conducted  to  determine  hepatoprotective  effect  of  ethanolic  extract  of Acalypha  indica  L.  leaves  on  rats  (Rattus  novergicus)  induced  with  paracetamol.  The  study  was performed  following  a  completely  randomized  design, using  45 male  rats  (Rattus  novergicus)  divided into  5  groups.  Rats  in  group  1  (K1)  were  given  CMC  1  %  for  7  days  and  followed  by  aquadest administration 8 hours post given CMC on day 7. Group 2 was given CMC 1 % for 7 days and treated with paracetamol at dose 2,5 g/kg BW 8 hours post given CMC on day 7. Groups 3 (K3), 4 (K4), and 5 (K5) were pretreated with ethanolic extract of Acalypha indica L.  leaves at the dose of 50, 100, and 200 mg/kg BW for 7 days respectively, followed by paracetamol administration at the dose of 2.5 g/kg BW in the  next  8  hours  on  day  7. Paracetamol  hepatotoxicity  and  extracts  activity were measured  based  on SGPT and SGOT activity level on day 0, 8 hours after  last administration of  extract on day 7, and 24 hours post paracetamol administration. Data were analyzed using one way ANOVA. The result showed that  the  administration  of  ethanolic  extract  of Acalypha  indica  leaves  at  the  dose  of  50,  100,  and  200 mg/kg BW was  significantly  reduced SGPT  and SGOT  level  (P<0,05)  in  rats  that were  induced with paracetamol. Based on the results of SGPT and SGOT serum activity, it can be concluded that ethanolic extract of Acalypha indica L. potential as hepatoprotective agent.
Mammary Gland Tumor In Cat And Therapeutic Approach: A Case Report Hambal, Muhammad; Ayuni, Rizka; Vanda, Henni; Sabri, Mustafa
The International Journal of Tropical Veterinary and Biomedical Research Vol 3, No 1 (2018): Vol. 3 (1) May 2018
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (354.318 KB) | DOI: 10.21157/ijtvbr.v3i1.11432

Abstract

This report describes a case of mammary gland tumor in a 1-year-old female cat using a mastectomy approach. The tumor was located on dexter side of mammae. Blood analysis showed good condition of the patient and ready for surgery. Mastectomy was conducted to remove the mass, and the tumor size was measured 7x5x4 cm with solid appearance. The cat was given antibiotics to prevent infection, and the wound dried in five days.
Histopathological Changes of Egg Cells in the Uterine of Ascaridia galli after Treatment with Extract of Veitchia merrillii Nuts Balqis, Ummu; Muslina, Muslina; Hambal, Muhammad; Athaillah, Farida; Muttaqien, Muttaqien; Azhar, Azhar; Ismail, Ismail; Rastina, Rastina; Eliawardani, Eliawardani; Harris, Abdul; Hamzah, Abdullah; Vanda, Henni; Darmawi, Darmawi
Majalah Obat Tradisional Vol 22, No 3 (2017)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.31544

Abstract

The aim of the study was to observe the histopathological changes of the entire egg cells in the uterine of Ascaridia galli worms treated with crude ethanolic extract of Veitchia merrillii nuts. Histopathological changes of the entire egg cells were observed to describe that the activity of extract V. merrillii nuts interfered the reproduction process could decrease the quantity and quality of A. galli eggs. The experiments consisted of 16 head A. galli female adult worms divided into four groups, contained four worms of each, and maintained in 0.9% phosphate buffered saline (PBS). First group, a negative control experiment consisted of A. galli in 0.9% PBS. Second group, concentration of 15 mg/mL albendazole was used as a positive control. Third group and fourth group, in vitro exposure of the worms to the crude ethanolic extract V. merrillii nuts at a concentration of 25 mg/mL and 75 mg/mL, respectively. The histopathological changes of egg cells in the uterine region of stained worms was evaluated by light microscopic examination at 40x magnification. The results showed that shrinkage and disintegration of the entire egg cells in the breakage of uterus. The results indicate that the possible use of the plant as a potential anthelmintic against A. galli, the intestinal nematode parasite of domestic fowl.
Combination of Areca catechu , Sauropus androgynous , and Mineral Block is Effective to control Nematode in Goats Vanda, Henni; Hambal, Muhammad; Athailah, Farida; Sabri, Mustafa
The International Journal of Tropical Veterinary and Biomedical Research Vol 2, No 2 (2017): Vol. 2 (2) November 2017
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.557 KB) | DOI: 10.21157/ijtvbr.v2i2.9630

Abstract

A study has been conducted to investigate the effect of two local herbs in Indonesia; Areca catechu nut and Sauropus androgynous leaf, combined with mineral block to treat gastro intestinal nematode in goats. A.catechu is well known to have anthelmintic property due to its alkaloid and tannin content, and S.androgynus also contains tannin, alkaloid and steroid that will enhance the anthelmintic property of those herbals.  As many as 80 goats had been divided into 4 groups; 20 were treated with albendazole (Group A), 20 were given A.catechu and S.androgynus (Group B), 20 were given combination of A.catechu, S.androgynus, and mineral block (Group C), and 20 as negative control (Group D). The result revealed that herbal treatment showed significantly effective toward nematodes in gastro intestinal, demonstrated by declining egg worm of Group B and C. Body weight improvement and overall performance in Group C was higher compared to other groups. However, goats treated with albendazole showed slightly better results in the decreasing amount of egg worms found after treatment. Nevertheless, A.catechu and S.androgynus are potential anthelmintic herbal; combination with mineral block will enhance the anthelmintic activity. Therefore they are good options for treating helminthiasis in livestock.   
8. Aedes Mosquitoes Abundance In Relation To Some Climatic Factors In Banda Aceh City, Indonesia Athaillah, Farida; Hambal, Muhammad; Fahrimal, Yudha; Bakri, Muttaqien; Ellyawardani, Ellyawardani; Vanda, Henni; Ahmad, Abu Hassan
The International Journal of Tropical Veterinary and Biomedical Research Vol 1, No 1 (2016): Vol. 1 (1) May 2016
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (205.018 KB) | DOI: 10.21157/ijtvbr.v1i1.5393

Abstract

Dengue viruses and their mosquito vectors as an endemic disease in Indonesia are sensitive to their environment. The rising incidence of dengue is influenced by many factors, climate is one of them. Temperature, rainfall and humidity have well-defined roles in the transmission cycle. Changes in these conditions may contribute to increasing incidence. The purpose of this research was to determine the correlation between the dengue vector abundance and some climatic factors (temperature, rainfall and humidity) in Banda Aceh city after the tsunami. We also examined the potential effects of climate variations on dengue epidemiological pattern in indoor and outdoor of tsunami affected areas in Banda Aceh City during January – December 2010. Data processing was performed using SPSS and will be presented in tabular form. Pearson correlation test for parametric test and Spearman correlation coefficients for non-parametric test were performed to investigate the overall correlation between Aedes eggs abundance rates and some meteorological variables such as temperatures (0C), relative humidity (RH), and rainfall (RR). The result showed that the total egg populations in indoor and outdoor of tsunami affected areas are not significantly different among those factors. There was a positive correlation between eggs abundance and rainfall, but negatively correlated with temperature and relative humidity. From this result we can conclude that the abundance of Aedes eggs is not significantly correlated to temperature and humidity in indoor and outdoor of tsunami affected areas in Banda Aceh City.