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All Journal Jurnal Civics: Media Kajian Kewarganegaraan ILMU KELAUTAN: Indonesian Journal of Marine Sciences Prosiding KOMMIT Lingua Didaktika: Jurnal Bahasa dan Pembelajaran Bahasa Gorga Jurnal Seni Rupa Pembelajaran Matematika Paedagogia Jurnal Pendidikan Matematika SoLuSi ( Tersohor Luas dan Berisi ) Atom Indonesia Journal Jurnal Radioisotop dan Radiofarmaka Jurnal Iptek Nuklir Ganendra Jurnal Pendidikan Teknik Mesin Jurnal Manajemen Pelayanan Kesehatan Gaung Informatika Journal of Education and Learning KOMUNITAS: INTERNATIONAL JOURNAL OF INDONESIAN SOCIETY AND CULTURE Abdimas Jurnal S2 Pendidikan Matematika YUSTISIA Jurnal Penelitian Hasil Hutan Jurnal Ilmu-Ilmu Perikanan dan Budidaya Perairan Jurnal Akuntabilitas Manajemen Pendidikan Seminar Nasional Teknik Kimia Kejuangan The Journal of Pure and Applied Chemistry Research Indonesian Journal of Pharmaceutical Science and Technology Journal of Mathematics and Mathematics Education BERITA BIOLOGI Sari Pediatri Catharsis The Journal of Educational Development Sekolah Dasar: Kajian Teori dan Praktik Pendidikan EDUHUMANIORA: Jurnal Pendidikan Dasar Proceeding of International Conference on Art, Language, and Culture Jurnal Pembelajaran Matematika Jurnal ASPIKOM Indonesian Journal of Chemistry Jurnal Perikanan Universitas Gadjah Mada Indonesian Aquaculture Journal Indonesian Fisheries Research Journal Jurnal Community Res Judicata Waskita: Jurnal Pendidikan Nilai dan Pembangunan Karakter Jurnal Jatiswara Jurnal Kesehatan Jurnal Salaka Sastra Indonesia
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Journal : Indonesian Journal of Pharmaceutical Science and Technology

Preliminary Study on Production Of 32P – Labeled Phosphate Chromic as A Material for Skin Patch

Indonesian Journal of Pharmaceutical Science and Technology Suppl. 1, No. 3 (2019)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

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Abstract

Keloids are skin disorders or benign tumours that are due to abnormal wound healing in the binding tissue after a trauma, inflammation, surgical wounds, or burns. Low activity radioisotopes have shown to be effective in curing or eliminating keloids on the skin. One of these radioisotopes is phosphorus-32 (32P), a beta (β-) emitter with a half-life of 14.3 days. This radioisotope can also be developed for the treatment of keloid and skin tumours. Currently, keloid is treated by a conventional method e.g.by applying the bulk of 32P radioisotope directly on keloid area. However, this method is considered inefficient and less secure. The purpose of this research is to obtain a technology for preparing of 32P-labeled skin patch. The first step of this research is to produce 32P-labeled chromic phosphate (Cr32PO4) colloids, through condensation involving oxidation-reduction reaction. In this step, Cr (VI) is reduced to Cr (III) to form Cr32PO4 with particle size of <1 μm.  These particles (Cr32PO4) are to expect to distribute evenly when mixed with silicon to form skin patch which will not decompose easily. Characterization of the prepared Cr32PO4colloids gave a yield of 97,8% with particle size of greater than > 1μm.  Further study needs to be performed in due time in order to have Cr32PO4 colloids with a suitable particle size.Key words: keloid, chromic phosphate colloid, skin patch, condensation, oxidation-reduction reaction

Co-Authors A. Isnansetyo, A. A.E.T.H. Wahyuni Abdul Muthalib Abidin Abidin Agus Cahyono Agus Nursalim, Agus Agustiar, Devie Ahmad, Hariyatunnisa ALIM ISNANSETYO Ambariyanto , Andriansyah, Rico Andrianus Andrianus, Andrianus Anik Rahmawati, Anik Anshor, Arrini Shabrina Anung Pujiyanto Ardiyawan, Ardiyawan Arief Taslihan Arief, Ahmad Fikri Astri Charolina Azmi, Azmi Azmi, Ulya Zakaria Basri, Novysa Basuki, Umar Beniarso, Mundin Cahyana Amiruddin Darfioes Basir Daya Agung Sarwono Desrina Desrina Desty Ratna Permatasari, Desty Ratna Dian Indriani Dini Siswani Mulia Dini, Tria Ayu Drajad Sarwo Seto, Drajad Sarwo Duranta D. Kembaren, Duranta D. Dwiningtyas, Ratih Dyah Indriyani, Putri E. Sarmini Edi Irawan Eko Sugiarto, Eko Endang Sarmini Enny Lestari Erik, Mohamad Erni Martani Ervia Yudiati FAJAR SETIAWAN Fatimah Azzahrah Fatmawati, Harlinda Fauziyah, Fuzi Afiza Finny Fitry Yani Fitriani Fitriani H. Syakuri, H. Habib Adjie Hadi, Muhammad Tesar Hambali Hambali Hartono Hartono Henny Ekana Ch. Henny Ekana Chrisnawati Herlina Herlina Hotnida Junita Situmeang Imamudin, Kurniasih INDAH ISTIQOMAH Irfan D. Prijambada Islami, Hidayatul Iswidiarti, Sri JAKA WIDADA K. H. Nitimulyo, K. H. Kadarisman Kadarisman Kamiso H. N., Kamiso H. KAMISO HANDOYO NITIMULYO KH, Abdul Aziz Kundharu Saddhono Kurniasih Kurniasih LANGKAH SEMBIRING Lantip Diat Prasojo Lestari, Fajar Sumi Lili Sholichah, Lili Ma'sum, Aziz Malarsih Malarsih, Malarsih Manik, Astri Marita Mardi Mardi Mardiyana Mardiyana Maria Ulfahmi, Cut Gesti Mayang Pitaloka MIFTAKHUL JANNAH Mirwa, Tetty Muh. Ibnan Syarif, Muh. Ibnan Muhammad Murdjani Muhammad Zainuddin Muhammmad Murdjani, Muhammmad Mujiyono Mujiyono Murti, Fahriza Murwantoko Murwantoko Namastra Probosunu Nina Yuliana Ningsih, Maya Nirmalasari Idha Wijaya Noer Kasanah, Noer Nur Fadhilah Nur Rokhmat Nursyirwani Nursyirwani Pratiwinindya, Ratih Ayu Prayogo, Sugeng Putri Puspitasari R Sudradjat, R Rachmansyah Rachmansyah Raden Bagus Sugio Sumanta Ratna Puspita, Ratna REZA Adi ADI PRADANA Risca Damayanti, Risca Risnawati, Ririn Riyadi Riyadi Rukayah Rukayah S. Soenarjo Sabillah, Masayu Selly Sahli, Zamahsjari Salu, Vega Ricky SANTI NURBAITI Sebastian Margino Sesung, Rusdiyanto Setyaningrum, Ikha Sulis Setyobudi Setyobudi Shanie, Arsan Shatrie, Dikry N Shatrie, Dikry Novel Siti Amirah Budiastuti Sri Hartati Sri Iswidayati Sri Rejeki Sriyono Sriyono Subagiyo Subagiyo Suharno Suharno Suherman Suherman Sumarwati Sumarwati Sumaryanto Florentinus, Totok Sunarhadijoso Soenarjo Sunarto Sunarto Suparti Suparti Sutarman Sutarman Sutrisno sutrisno Suyono Suyono syakir syakir Syarif, Muh Ibnan Tanjung, Dailami Tjetjep Rohendi Rohidi, Tjetjep Rohendi Totok Sumaryanto Florentinus, Totok Sumaryanto Totok Sumaryanto, Totok Triani Widyaningrum Udi Utomo Umi Nur Sholikhah W. Asmara W.Y. Rahman Wadiyo Wadiyo, Wadiyo Wardani, Anestia Widya Widaningtyas H, Adoniati Meyria Wijaya, Dhimayu Ichtiara Wilis Ari Ari Setyati1,2, Wilis Ari Wilis Ari Setyati Windi Amelia, Windi Wira Rahman Wira Y. Rahman Wisnu Nurcahyo Wulandari, Tita Yudha Trinoegraha Adiputra Yulius Docang Casessar Yuniarti, Ivana