Slamet Suyono
Department of Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta

Published : 5 Documents
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Infection at Insulin Injection Sites in Diabetic Patients with or without Alcohol Swab Kshanti, Ida Ayu; Suyono, Slamet
Journal of the Indonesian Medical Association Vol. 58 No. 9 September 2008
Publisher : Journal of the Indonesian Medical Association

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Abstract

Patient compliance to aseptic standard procedure is questionable. However, report from Western country did not find any infection at the site of injection. This is a prospective study, pro-experimental design before and after, to elucidate the difference of local infection occurred at an injection site between two procedure of subcutaneous insulin injection using insulin pen devices: with and without alcohol swab. The study was conducted in an outpatients clinic of Fatmawati General Public Hospital, Jakarta. There were 76 diabetic subjects on insulin therapy, without skin disparity or any known skin diseases were asked not to use alcohol swab before injecting insulin during a 2 weeks period. Then during the next 2 weeks period they were asked to swab the skin with individually foil wrapped swabs isopropyl alcohol 70% for several seconds and awaiting until the alcohol dry spontaneously before insulin was injected subcutaneously. Any sign of infection defined as any erythema, edema or tenderness at the site of injection should be self reported. Observation by the investigator was done once a week. Data analysis was done using STATA 8.1 software. A total of 1512 times insulin injection without alcohol swab and 1512 times insulin injection with alcohol swab were done in this study. There was no local skin infection, nor as reported by the subject and the investigator. There was no significance difference between using skin preparation and without skin preparation before injecting insulin as shown by McNemar test (p= 0.625 CI: 95% 0.034-3.204). That the modification of education giving to the Indonesian diabetes patients regarding insulin injection technique especially without skin preparation may be much more accepted or preferred by Indonesian diabetes patients because it was not harmful, simpler and less expensive.Keywords: Subcutaneous insulin injection, alcohol swab, local infection
Cut-off Levels of High Sensitive C-Reactive Protein in Coronary Acute Syndrome Alwi, Idrus; Santoso, Teguh; Suyono, Slamet; Sutrisna, Bambang; Kresno, Siti Boedina
Journal of the Indonesian Medical Association Vol. 60 No. 12 December 2010
Publisher : Journal of the Indonesian Medical Association

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Abstract

Acute coronary syndrome (ACS) is the gravity of cardiac inflammatory response characterized by activation of macrophages and T lymphocytes that release various cytokines. These cytokines will induce the formation of acute phase reactants, C-reactive protein (CRP) in the liver. Research on population indicates that high sensitive C-reactive protein (hs-CRP) level is an independent risk factor for coronary heart disease (CHD) in both men and women. The purpose of this study was to determine the cut-off levels of hs-CRP in acute state (ACS) with stable condition (CHD). A cross sectional observational study was conducted comparatively with consecutive sample selection to ACS or CHD patients. Levels of hs-CRP were analyzed by unpaired t test followed by sensitivity and specificity test. It was showed that average concentration of hsCRP in ACS group (mean 82.96 mg/L, SB 79.70, 95% CI 65.67-100.26) was significantly higher than the CHD group (mean 5.12 mg/L, SB 8.44, 95% CI 2.97-7.26). Levels of hs-CRP with cut-off point >8.23 mg/L have sensitivity of 88.10%, specificity 88.71%, with ROC 0.94. In conclusion, levels of hs-CRP with cut-off point >8.23 mg/L, could distinguish ACS and CHD with the highest sensitivity and specificity (sensitivity 88.10%, specificity 88.71%, ROC 0.94).Keywords: ACS, cut-off, hsCRP
Interleukin-10 serum level in acute coronary syndrome patients Alwi, Idrus; Santoso, Teguh; Suyono, Slamet; Sutrisna, Bambang; Kresno, Siti B.
Medical Journal of Indonesia Vol 18, No 3 (2009): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (377.652 KB) | DOI: 10.13181/mji.v18i3.358

Abstract

Aim To compare plasma IL-10 concentrations in patients with Acute Coronary Syndrome (ACS) with those in Coronary Artery Disease (CAD).Methods ACS patients hospitalized in intensive coronary care unit (ICCU) of Cipto Mangunkusumo Hospital/Faculty of Medicine University of Indonesia (CMH/FMUI), Persahabatan Hospital, MMC Hospital, and Medistra Hospital, Jakarta, between May 2005 and May 2006, were included in this study. The ambulatory CAD patients were taken as comparator. The serum IL-10 level was measured by immunoassay method, and compared by using Independent Student’s t-test. To investigate whether IL-10 serum level could predict ACS, the sensitivity and specificity of this parameter towards ACS in various IL-10 serum levels were calculated as well.Results In this observational study, as many as 146 subjects were analyzed, consisting of 84 ACS patients, and 62 coronary artery disease (CAD). The IL-10 level was higher in the group of ACS patients (7.37 pg/mL + 7.81, CI 95% 5.68-9.07) than that in CAD patients (1.59 pg/mL + 1.55, CI 95% 1.2-1.98). The optimal cut-off point for serum IL-10level is >1.95 pg/mL, with 79.76 % sensitivity and 77.42 % specificity.Conclusion The IL-10 level was higher in the ACS patients compared to that in CAD patients. Serum IL-10 measurement is a quite superior method to distinguish acute and stable condition, eventhough it is not as good as hsCRP for the same purpose. (Med J Indones 2009;18:165-9)Key words: Interleukin-10, acute coronary syndrome
The outcome of pregnancy among Graves women treated with PTU Mukhsin, Ali I.; Waspadji, Sarwono; Subekti, Imam; Soegondo, Sidartawan; Ranakusuma, Asman B.; Suyono, Slamet
Medical Journal of Indonesia Vol 9, No 4 (2000): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (822.657 KB) | DOI: 10.13181/mji.v9i4.623

Abstract

[no abstract available]
PENINGKATAN KOMPETENSI SUMBER DAYA MANUSIA MELALUI KEMAMPUAN INTELEKTUAL, PEMBELAJARAN INDIVIDUAL DAN KEMAMPUAN PENYERAPAN PENGETAHUAN Suyono, Slamet
Jurnal Riset Bisnis Indonesia Vol 12, No 1 (2015): Jurnal Riset Bisnis Indonesia
Publisher : Fakultas Ekonomi Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (71.575 KB) | DOI: 10.30659/jrbi.v12i1.982

Abstract

This study is to describe and analyze the improvement of the competence of human resourcesthrough intellectual ability, individual learning and knowledge absorption capability. The purposeof this study to examine and analyze 1) the effect of intellectual ability to the competence 2)the influence of individual learning on the competence, 3) the effect of intellectual ability to theabsorption of knowledge 4) the effect of individual learning to the knowledge absorption capacity 5)the effect of absorption of knowledge to the competence. This study was conducted to Employeesin the Department of Revenue, Finance and Asset Management District Semarang. The methodof data collection in this study through a list of questions / questionnaire with 80 respondents forsample. Based on SEM analysis the results showed that if the intellectual capability increases, thecompetence of human resources is increasing, if the individual learning increases, the competenceof human resources is increasing, if the intellectual capability increases, the absorption of knowledgeis increasing, if individual learning increases, the absorption knowledge is increasing, and if theknowledge absorption capacity increases, the competence of human resources is increasing. Themanagerial implications of this study are as follows; associated with increasing intellectual ability,individual learning, knowledge absorption capability and competence of the employees in RevenueService Financial and Asset Management should be given awards (reward), those are by improvingeducation, training, education and training, technical assistance, mutation in order to increaseknowledge transfer even promotion position or promotion to positions.Keywords :intellectual ability, individual learning, knowledge absorption and capability competence