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Higher Education Leadership: Challenge of the 21st Century Sutjipto, Sutjipto
Jurnal Ilmu Pendidikan Vol 6 (1999): Edisi Khusus
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/jip.v6i0.867

Abstract

In the 21 st century, higher education (HE) will play a very crucial role; in spite of its limited resources, HE should be able to respond to the challenges caused by the very fast advancement of technology. For this purpose managers of HE should be professional, those who are prepared to become the managers, so that they reflect wide perspectives, good attitudes, and quality skills in managing the HE in such a competitive era. Higher education leadership is expected to make use of the system and opportunity to improve its performance
First-line chemotherapy of advanced or metastatic breast cancer (MBC) with docetaxel and doxorubicin in Indonesia: results from A phase II trial Abdulmuthalib, Abdulmuthalib; Darwis, Idral; Prayogo, Nugroho; Sutjipto, Sutjipto
Medical Journal of Indonesia Vol 14, No 1 (2005): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i1.166

Abstract

Doxorubicin and docetaxel as a single agent are known as active cytotoxic agents for the treatment of metastatic breast cancer (MBC). Their combination has also shown to be highly active as a second-line chemotherapy of MBC. This study was design to evaluate the efficacy and safety of docetaxel-doxorubicin combination as first line chemotherapy of MBC patients in Indonesia. Twenty-six female patients between 31-65 years old with advanced or MBC was enrolled. No prior taxane or cumulative doxorubicin of 250 mg/m2 was allowed and patients should not have a heart disease. Treatment consisted of doxorubicin 50 mg/m2 as intravenous (IV) bolus followed one hour later by docetaxel 60 mg/m2 by IV infusion over 1 hour every 3 weeks for 6 cycles. Premedication with oral corticosteroid was administered a day prior to chemotherapy until the second day of each cycle. Left ventricular ejection fraction was recorded at baseline and after the 6th cycle. At the end of study, a total of 156 cycles of chemotherapy have been delivered.  Five and 11 patients had a complete response (CR) and partial response (PR), respectively, which accounted for a 61.54% best overall response. Three patients with extensive liver metastases showed complete disappearance after 6 cycles. Most frequent grade 3-4 toxicities were leukopenia (80.77%) and febrile neutropenia (5.77%). Leukopenia was usually short in duration, occurred mainly during the first and second cycle and did not require dose reduction. No patient developed heart failure. There was one death due to progressive disease after 6 cycles. Combination of doxorubicin 50 mg/m2 and docetaxel 60 mg/m2 was sufficiently active as first-line chemotherapy of MBC, especially in patients with liver metastases, with a manageable toxicity profile. (Med J Indones 2005; 14: 20-5)Keywords: docetaxel, doxorubicin, advanced or metastatic breast cancer, phase II trial, anthracycline and taxane combination
Bantuan Teknis Profesional Pengembangan Kurikulum Kepada Tim Pengembang Kurikulum Daerah Sebagai Wahana Pemberdayaan Staf Pusat Kurikulum Sutjipto, Sutjipto
Jurnal Pendidikan dan Kebudayaan Vol 17, No 3 (2011)
Publisher : Balitbang Kemendikbud

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Abstract

This study set out to get a view of empowerment Curriculum Center staff through a strategy of professional technical assistance activities in the area of curriculum development. Methods This study is descriptive, where the main data is processed based on program activities, implementation activities, and report the results of activities Curriculum Center between 2006 through 2010 related to the professional technical assistance to the TPK provincial curriculum development in 33 provinces, and TPK district in 120 districts/cities. Information was collected using documentary techniques, focus group discussions, and involved role in the activities. The data analysis technique used, namely description, and interpretation. The study shows that the increase in professional skills (professional development) staff in curriculum development is really a conscious and sustained effort from the leadership of Curriculum Centre. The importance of the creation of a cultural institution with the atmosphere or climate that allows staff to develop, a sound management in strengthening the potential or staff resources and the protection jaminnan staff so that potential can be constructed in a positive and conducive environment which in turn can memandirikan staff in making the work is also a prominent finding in this study. Furthermore, this study also shows that the strategy of empowering the staff at the Curriculum Center is very influential on the successful achievements of technical assistance activities of professional development curriculum to local corruption. ABSTRAKKajian yang dikemukakan ini dimaksudkan untuk memperoleh gambaran tentang pemberdayaan staf Pusat Kurikulum melalui strategi kegiatan bantuan teknis profesional pengembangan kurikulum di daerah. Metode kajian ini yaitu deskriptif, di mana data utama diolah berdasarkan program kegiatan, pelaksanaan kegiatan, dan laporan hasil kegiatan Pusat Kurikulum tahun 2006 s.d. tahun 2010 berkait dengan bantuan teknis profesional pengembangan kurikulum kepada TPK provinsi di 33 provinsi, dan TPK kabupaten/kota di 120 kabupaten/kota. Informasi dikumpulkan dengan menggunakan teknik dokumentasi, diskusi terfokus secara kelompok. Teknik analisis data yang dipergunakan, yaitu deskripsi, dan interpretasi. Hasil kajian menunjukkan bahwa peningkatan kemampuan profesional staf dalam pengembangan kurikulum merupakan usaha sadar dan berkesinambungan dari pimpinan Pusat Kurikulum. Pentingnya penciptaan suatu budaya kelembagaan dengan suasana atau iklim yang memungkinkan staf berkembang secara sehat dalam manajemen yang memperkuat potensi staf dan adanya jaminan perlindungan. Dengan demikian, potensi staf dapat dibangun secara positif dan kondusif yang pada gilirannya bisa memandirikan staf dalam berkarya. Kajian ini menunjukkan juga bahwa strategi pemberdayaan staf di tingkat Pusat Kurikulum sangat berpengaruh terhadap capaian keberhasilan kegiatan bantuan teknis profesional pengembangan kurikulum kepada TPK daerah.
PEER COACHING SEBAGAI WAHANA GURU UNTUK BERKOLABORASI MELALUI TEKNOLOGI INFORMASI DAN KOMUNIKASI Sutjipto, Sutjipto
Jurnal Pendidikan dan Kebudayaan Vol 13, No 65 (2007)
Publisher : Balitbang Kemendikbud

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Abstract

Dengan kemudahan yang  ditawarkan data internet tidak heran jika  saat  ini semakin  banyak bidang pekerjaan yang mengoptimalkan fungsi teknologi tersebut, termasuk bidang pendidikan. Sa/ah satu program yang  telah memanfaatkan internet da/am pengajaran  dan pembelajaran  di sekolah adalah apa yang disebut dengan program peer coaching. Peer Coaching adalah suatu strategi pengembarigan profesionalisme guru yang ditujukan untuk meningkatkan hubungan antarmitra kerja {peer)yang  bersifat collegial dan mengembangkan proses pengajaran, be/ajar, dan pembelajaran. Dalam peer coaching  biasanya para  guru  secara bersama-sama berbagi ide-ide baru, melakukan observasi kelas, merefleksikan dan memperbaiki  cara-cara mereka mengajar. Hubungan mereka dibangun alas dasar kepercayaan dan kejujuran, bukan ancaman, serta menjamin lingkungan di mana mereka be/ajar dan tumbuh  bersama-sama. Oleh karena itu, peer  coaching  tidak menghakimi (non judgmental) dan tidak bersifat evaluatif  Program Peer Coaching memfokuskan pada pengembangan kolaborasi, perbaikan serta berbagi pengetahuan, keterampilan, dan pengalaman dengan mengoptimalkan fungsi  teknologi informasi dan komunikasi. Peer coaching tidak untuk mata pelajaran tertentu, melainkan untuk semua mata pelajaran, sehingga dapat disesuaikan dengan disiplin ilmu apa pun, termasuk pengintegrasian teknologi  dalam pembelajaran.
A Study of The Assessment for Boron Neutron Capture Therapy Agent Triatmoko, Isman Mulyadi; Sutjipto, Sutjipto
Indonesian Journal of Physics and Nuclear Applications Vol 2 No 1 (2017)
Publisher : Fakultas Sains dan Matematika Universitas Kristen Satya Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24246/ijpna.v2i1.9-19

Abstract

A study of the assessment criteria covers the synthesis and characterization of agent and test their biological effectiveness as boron neutron capture therapy (BNCT) agents in cancer treatment. The cellular uptake of this agent into the glioblastoma cells was assessed by boron analysis (ICP-MS) and by fluorescence imaging (confocal microscopy). The agent enters the glioblastoma cells exhibiting a similar profile, i.e., preferential accumulation in the cytoskeleton and membranes and a low cytotoxic activity (IC50 values higher than 200 μM). The cytotoxic activity and cellular morphological alterations after neutron irradiation in the Research Reactor (>107 neutrons cm−2 s−1) were assessed by the MTT assay and by electron microscopy (TEM). Post neutron irradiation revealed that BNCT has a higher cytotoxic effect on the glioblastoma cells. Results provide a strong rationale for considering one of these compounds as a lead candidate for a new BNCT agent.
Assessment of Analytical Instrumentation for Boron Measurement in BNCT System Triatmoko, Isman Mulyadi; Sutjipto, Sutjipto
Indonesian Journal of Physics and Nuclear Applications Vol 2 No 1 (2017)
Publisher : Fakultas Sains dan Matematika Universitas Kristen Satya Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24246/ijpna.v2i1.20-33

Abstract

The methods boron measurement in BNCT system has generally progressed with developments in analytical instrumentation. Spectrophotometric methods remained the methods of choice for most routine applications until the development of ICP-OES. ICP-OES was also not adequately sensitive for nutritional and medical research involving animal tissues that are naturally low in boron (B). The development of plasma-source MS (e.g., ICP-MS) not only has overcome most of these drawbacks, but also its capability of measuring B isotopes. The application of nuclear reaction methods (mainly prompt-γ spectrometry) has remained limited to some specialized fields. The validity and comparability of three different analytical techniques (QNCR, PGAA, and ICP-MS) for boron measurement in biological samples and application of these methods for examination of blood and tissue samples from a clinical study on boron uptake in blood, tissue, and neoplastic tissue, after infusion of BPA. The PET-based approach to TPS has been applied in BDTPS and a preliminary evaluation of the correct operation has been performed using a heterogeneous boron phantom, called HEBOM. The validation has been accompanied by calculations done with SERA, following the standard approach. BDTPS needs further in vivo experimental validations.
Histological changes during orthodontic tooth movement due to hyperbaric oxygen therapy Brahmanta, Arya; Sutjipto, Sutjipto; Narmada, Ida Bagus
Dental Journal (Majalah Kedokteran Gigi) Vol 49, No 2 (2016): (June 2016)
Publisher : Faculty of Dental Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v49.i2.p63-66

Abstract

Background: Mechanical force of orthodontics causes changes in periodontal ligament vascularization and blood flow, resulting in biochemical and cellular changes as well as changes in the contour of the alveolar bone and in the thickness of the periodontal ligaments. Hyperbaric oxygen (HBO) therapy is one of many solutions stimulating the growth of new blood vessels and increasing tissue oxygenation. Thus, HBO plays a role in recovery of periodontal ligament and osteoblasts. Purpose: This study aimed to determine the effects of HBO therapy for seven days on periodontal ligament size and osteoblast number in the tension site during bone remodeling in tooth movement. Method: The study was true experimental laboratories with completely randomized control group post test only design. Twenty-four males guinea pigs were randomly divided into three groups. K0 was the control group without any treatment, K1 was the group given a mechanical orthodontic pressure, and K2 was the group treated with the addition of hyperbaric oxygen therapy. The maxillary incisors were moved distally by elastic separator. After HBO therapy on day 7, all of the groups were sacrificed, and then periodontal ligament size and osteoblast number were analyzed by one-way Anova and LSD statistical tests. Result: The results showed significant differences in the size of the periodontal ligament and the number of osteoblasts in the tension site among the groups (p<0.05). Conclusion: HBO therapy at 2.4 ATA for 7 days is effective in recovery of periodontal ligament and increased osteoblast number during bone remodeling in tension area of orthodontic tooth movement.
Penentuan kandungan logam di dalam sedimen waduk Gajah Mungkur dengan metode analisis aktivasi neutron cepat. Sudaryo, Sudaryo; Sutjipto, Sutjipto
Jurnal Forum Nuklir JFN Vol 5 No 1 Mei 2011
Publisher : BATAN

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Abstract

Penentuan kandungan logam di dalam sedimen waduk Gajah Mungkur dengan metode analisis aktivasi neutron cepat. Penelitian mengenai kandungan logam pada sedimen waduk Gajah Mungkur kabupaten Wonogiri telah dilakukan. Penelitian ini bertujuan untuk menentukan kandungan unsur logam di dalam waduk Gajah Mungkur kabupaten Wonogiri dengan metode AANC. Pencuplikan sedimen dilakukan di 3 (tiga) lokasi di daerah waduk tersebut. Pencuplikan pada bulan April 2008 dengan waktu pencuplikan pada jam 10.00-14.00 WIB. Kandungan unsur logam di waduk ditentukan dengan menggunakan Generator Neutron SAMES J-25 serta peralatan spektrometer gamma dengan detektor NaI(Tl) serta standar pembanding SRM 2704 (buffalo river sediment, BRS) dari NIST. Hasil penelitian menunjukkan bahwa konsentrasi kandungan unsur logam yang tersebar di dalam waduk pada lokasi 1 hingga 3 untuk Fe:7,4-32% Al: 12-16%; Si: 40% dan Cr total : 3-16 ppm. Adapun akurasi untuk unsur logam Fe, Al, Si dan Cr total mempunyai kisaran: 5,25 -10,75%; presisi : 10,99-14,25% dan batas deteksi untuk Al=1%, Na=0,14%, Mg=0,05%, Si=2%, Fe=1 % dan Cr=0,01 ppm. Didasarkan data penelitian menunjukkan bahwa di dalam sedimen waduk telah mengalami pencemaran unsur logam berat, utamanya unsur Cr total.
PENGEMBANGAN KURIKULUM PENDIDIKAN KESETARAAN Sutjipto, Sutjipto
Jurnal Ilmiah Visi Vol 11 No 2 (2016): VISI PTK PNF
Publisher : Direktorat Pembinaan Guru dan Tenaga Kependidikan, Pendidikan Anak Usia Dini dan Pendidikan Masyarakat bekerjasama dengan Fakultas Ilmu Pendidikan Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (284.925 KB) | DOI: 10.21009/JIV.1102.8

Abstract

The purpose of this research is to reveal how policy-makers and curriculum developers to design educational curriculum equality. This type of research is qualitative descriptive. The main data were collected by questionnaires and group discussions terpumpun. Data were analyzed using descriptive statistics, namely the depiction of the data with the pattern description. The study was conducted in November 2015 until June 2016, with a sample of teachers and education staff of three learning centers. The results showed. First, policy makers and developers are still putting that designing and realizing equality education curriculum has not made a top priority, but are waiting for formal education first. Second, policy makers and developers have not presenting concrete policy markers related complexity and context of the fundamental aspects of reality which represents the common interests of citizens of the nation that terejawantahkan in the curriculum as a tool tread life. Third, the design of educational curricula equality has not equip knowledge and competence as a prerequisite to work and also not strong attitudes toward integrity, hard work, discipline, mutual cooperation, independence, nationalism and specialized skills to solve the problem of life. Fourth, equal education curriculum design not describe the instruments to face the problem of dropouts and solve socio-economic problems oriented towards life skills in order to enter the life.
Kebijakan Penggunaan Batas Wilayah Epidemiologi dalam Pengendalian Penyakit Malaria (Studi Kasus di Puskesmas Kokap II Kabupaten Kulon Progo, DIY) Sutjipto, Sutjipto; Kusnanto, Hari; Trisnantoro, Laksono; Lazuardi, Lutfan; Astuti, Indwiani
Jurnal Kebijakan Kesehatan Indonesia Vol 4, No 2 (2015)
Publisher : Center for Health Policy and Management

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkki.v4i2.36100

Abstract

Background: There are 396 endemic districts from the total of 495 districts in Indonesia, with an estimated 45% of the population live in the areas that are at risk of infected malaria disease. Kulon Progo Regency is one of regencies in Yogyakarta (DIY), which until now has not declared elimination of malaria. PHC Kokap II located in Kokap sub-district, is the largest contributor of positive malaria cases in Kulon Progo regency due to the potential for outbreaks of malaria, during the period 1997-2004, when the number of malaria positive patients in the PHC Kokap II ranged between 26% - 55% of patients of the total positive malaria cases in Kulon Progo. This study aims to produce epidemiological information that is important in the region of PHC Kokap II associated with the distribution and determinants of malaria that affects the possibility of local transmission. Methods: The study design was a descriptive study, to get an overview of the distribution and determinants of malaria. The observation unit is the population in the form of correlation studies population and a time series. To determine the pattern of malaria transmission we use secondary data between 2009- 2012 malaria cases. Malaria incidence patterns were analyzed by person, place and time. To determine the clusters of malaria we use clustering analysis with the data of malaria cases in the region PHC Kokap II year 2012. To determine the spread of malaria in the cross-border area between PHC Kokap II and PHC Kaligesing we use secondary data year 2010-2012. Results: In the area of PHC Kokap II, we found import cases every year. Even more, in the year 2009 the proportion of import cases was 82% compared with all patients that were found malaria positive. Clusters of malaria is in the west region of PHC Kokap II, which is bordering to the Subdistrict Kaligesing, Purworejo, Central Java Province. Region PHC Kokap II is an area of high vulnerability, the potential to get the risk of transmission of imported cases of malaria is due to the entry of patients or infective vectors from high transmission areas to low transmission. Conclusion: The focus of malaria transmission in the area of PHC Kokap II is at the western part bordering the sub-district Kaligesing, Purworejo. PHC Kokap II is the region of high vulnerability. Policies need to be made use of epidemiological boundaries in the malaria control program in the cross-border region. Latar belakang: Di Indonesia masih terdapat 396 Kabupaten endemis dari 495 Kabupaten yang ada, dengan perkiraan seki- tar 45% penduduk berdomisili di daerah yang berisiko tertular malaria. Kabupaten Kulon Progo merupakan salah satu kabupa- ten di Daerah Istimewa Yogyakarta (DIY), yang sampai saat ini belum dinyatakan eliminasi. Wilayah Puskesmas Kokap II yang berada di Kecamatan Kokap, merupakan penyumbang terbesar penderita positip malaria untuk wilayah Kabupaten Kulon Progo diantaranya karena potensi terjadinya KLB malaria, selama periode tahun 1997-2004, range jumlah penderita positip ma- laria di wilayah Puskesmas Kokap II berkisar antara 26% - 55% penderita positip malaria di Kabupaten Kulon Progo. Pe- nelitian ini bertujuan untuk menghasilkan informasi epidemiologi yang penting di wilayah Puskesmas Kokap II terkait dengan distribusi dan determinan penyakit malaria yang sangat berpe- ngaruh terhadap kemungkinan terjadinya penularan setempat. Metode: Rancangan penelitian ini adalah studi deskriptif untuk mendapatkan gambaran distribusi dan determinan penyakit malaria, unit pengamatan adalah populasi dalam bentuk studi korelasi populasi dan rangkaian berkala. Untuk mengetahui pola penularan malaria digunakan data sekunder kasus ma- laria tahun 2009-2012, dianalisis pola kejadian malaria menurut orang, tempat dan waktu. Untuk mengetahui kluster penderita malaria dilakukan analisis klustering menggunakan data kasus malaria di wilayah Puskesmas Kokap II tahun 2012. Untuk mengetahui penyebaran penderita malaria di daerah lintas batas antara Puskesmas Kokap II Kabupaten Kulon Progo dan Pus- kesmas Kaligesing Kabupaten Purworejo digunakan data sekunder tahun 2010-2012. Hasil: Di wilayah Puskesmas Kokap II setiap tahun selalu dike- temukan kasus import, bahkan dalam tahun 2009 kasus import proporsinya adalah 82% dibandingkan dengan seluruh pen- derita positif malaria yang diketemukan. Kluster penderita ma- laria berada di bagian barat wilayah Puskesmas Kokap II, yaitu berbatasan langsung dengan Kecamatan Kaligesing Kabupaten Purworejo, Provinsi Jawa Tengah. Wilayah Puskesmas Kokap II merupakan daerah vulnerebilitas tinggi, potensial untuk menda- patkan risiko penularan kasus import karena masuknya pende- rita malaria atau vektor yang infektif dari daerah penularan tinggi ke penularan rendah. Kesimpulan: Fokus penularan penyakit malaria di wilayah Puskesmas Kokap II berada pada wilayah bagian barat berba- tasan dengan wilayah administratif Kecamatan Kaligesing, Ka- bupaten Purworejo. Puskesmas Kokap II adalah wilayah vulnerabilitas tinggi, perlu dibuat kebijakan penggunaan batas wilayah epidemiologi dalam program penanggulangan malaria di wilayah lintas batas.