Diana Sunardi
Faculty of Medicine, University of Indonesia

Published : 11 Documents
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Functional Constipation and its Related Factors Among Female Workers Bardosono, Saptawati; Sunardi, Diana
Journal of the Indonesian Medical Association Vol. 61 No. 3 March 2011
Publisher : Journal of the Indonesian Medical Association

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Abstract

Functional constipation is strongly associated to gender, age, and educational level. In spite of psychological factors, the poor dietary habit is mostly common as its cause. This study aims to see the prevalence of constipation and its related factors among female workers aged 18-55 y in Jakarta. A cross-sectional study was done to 210 female workers in two selected government offices in Jakarta. Interviews and physical assessments were done for collecting data on defecation habits and anthropometric measures. The median age of the subjects was 36 y, with median of waist-circumference was 81.40 cm (central obesity) and body mass index of 24 kg/m2 (overweight). This study found that constipation symptoms ranged as low as 47.6% (straining during defecation) to as high 63.8% (recurrent abdominal discomfort 3d/w). The prevalence of functional bowel disorders was 52.9% and it was significantly prevalent among those aged less than 30 years. This high prevalence of functional bowel disorders among female workers should be seriously addressed to prevent its health impacts. Promoting healthy lifestyle especially among those female workers aged less than 30 y is urgently needed.Key words: constipation, nutrition, women
The Role of High Protein Complimentary Feeding on Growth Status of Children Age 6-8 Months Sutanto, Luciana B.; Bardosono, Saptawati; Sunardi, Diana
Journal of the Indonesian Medical Association Vol. 60 No. 11 November 2010
Publisher : Journal of the Indonesian Medical Association

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Abstract

Adequate nutrition during infancy is fundamental for growth and development. The first and only nutrition for babies is breast milk, but by the age of six month, complimentary feeding is needed. A nutritionally adequate complimentary feeding for infant is very important for optimal growth and development. This study aims to evaluate the role of high protein complimentary feeding on growth status of infants age 6-8 months. A quasi-experimental study design was applied using cluster random allocation sampling technique. Infants age 6–8 months were divided to two groups receiving commercial complimentary feeding (MPASI-D) and to homebrews complimentary feeding (MPASI-I). All respondent were given infant feeding education before data collection and during the study. Infant’s growth indicators (weight, length and head circumference) were monitored. The study was done from November 2009 to April 2010, at several Posyandu in Kelurahan Kampung Melayu, East Jakarta. The result of this study showed that counseling and complimentary feeding for 3 months increase calories and protein intake and growth indicators in both groups. In conclusion, commercial high protein complimentary feeding is as good as the homebrews.Keywords: Complimentary feeding, growth, high protein, children age 6-8 month
Correlation between Zinc Intake and Zinc Serum Levels with C-reactive Protein Level in Head and Neck Cancer Patients Alam, Muningtya Philiyanisa; Sunardi, Diana; Rinaldi, Ikhwan
World Nutrition Journal Vol 2, No 2 (2019)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (280.316 KB) | DOI: 10.25220/WNJ.V02.i2.0003

Abstract

The inflammatory process of head and neck cancer leads to an increase the proinflammatory cytokines and the synthesis of c-reactive protein (CRP), which then causes metabolic alteration and anorexia in the patients. Zinc is one of  nutrient that has an important role in suppressing inflammation, but it is reported that about 65% of head and neck cancer patients have zinc deficiency. The aim of this cross sectional study is to determine the correlation between zinc intake and serum zinc levels with CRP level as an effort in reducing inflammation process in head and neck cancer patients. Subjects were collected by consecutive sampling in the Oncology Polyclinic Rumah Sakit Kanker Dharmais, from 49 subjects 67,3% were men, most subjects were in the age range between 46?65 years. The highest frequency (65,3%) is nasopharyngeal cancer and 69,4% are already in stage IV. All subjects (100%) in this study have a zinc intake below the recommended dietary allowance (RDA) in Indonesia. The mean serum zinc level of the subjects was 9.83±2.62 ?mol/L. Most subjects have elevated CRP levels. There was a weak negative correlation between zinc concentration and CRP levels of subjects (r =-0.292, p =0.042), but there was no correlation between zinc intake and CRP levels of subjects (r =-0.25).
Correlation between Serum Hugh Sensitivity C-Reactive Protein With Dietary Intake of Indonesian Lactating Mothers Wiradarma, Karin; Sunardi, Diana; Mudjihartini, Ninik
World Nutrition Journal Vol 3, No 1 (2019): Volume 03 Issue 1 Include Supplements Oral Presentation Abstracts of 14th Sympos
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (212.521 KB) | DOI: 10.25220/WNJ.V03.i1.0008

Abstract

Background and Objectives:Chronic low-grade inflammation has emerged as important pathophysiology of non-communicable diseases, which can cause negative effects to mother and baby. Dietary intake has been known as important factor to affect inflammation, which can be measured by high-sensitivity C-reactive protein (hs-CRP). This study aimed to examine the correlation between serum hs-CRP with dietary intake in lactating mothers.Methods:A cross-sectional study was conducted by consecutively enrolling 71 lactating mothers, 3-6 months post-partum, age 20-35 years old, visiting Grogol Petamburan and Cilincing community health center between February and April 2019. Dietary assessment was conducted using semi-quantitative food frequency questionnaire. Anthropometric measurements included were pre-pregnancy weight, post-partum weight, and body height. Serum hs-CRP was measured by immunoturbidimetry method. Spearman correlation was used, with p<0.05 considered significant.Results:Correlation was found between serum hs-CRP and energy (r = 0.372, p = 0.001), carbohydrate (r = 0.295, p = 0.013), and vitamin B6 (r = -0.285, p = 0.016) intake. We also found that serum hs-CRP was correlated with pre-pregnancy (r = 0.296, p = 0.012) and post-partum BMI (r = 0.430, p<0.001).Conclusion:Energy, carbohydrate, and vitamin B6 intakes are positively correlated with serum hs-CRP level.
Serum Lactate Dehydrogenase Activity and Its Corellation with Carbohydrate Intake in Advanced Lung Cancer Patients diella, claresta; Mudjihartini, Ninik; Sunardi, Diana; Chandra, Dian Novita; Yulhasri, Yulhasri; Jayusman, Achmad Mulawarman
World Nutrition Journal Vol 2, No 2 (2019)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (307.696 KB) | DOI: 10.25220/WNJ.V02.i2.0002

Abstract

Introduction : The aim of this study was to determine serum lactate dehydrogenase activity and its correlation with carbohydrate intake in advanced lung cancer patients at Dharmais National Cancer Hospital Jakarta. Cancer Cells are characterized by increase anaerobic glycolysis termed the Warburg effect with lactate as an end product, catalyzed by LDH enzyme. Activities of lactate in cancer influences on tumor growth initiation, survival, proliferation, angiogenesis and metastasis. Serum LDH activity can be used as a diagnostic, prognostic, and predictive marker for tumor sensitivity and resistancy to therapy.Methods :56 subjects of advanced lung cancer from Dharmais National Cancer Hospital Jakarta were included in this cross sectional study. Subjects were recruited by consecutive sampling. Food intake of total carbohydrate was obtained by utilizing 24 hours food recall method. The activity of  serum LDH (IU/L) was measured by using enzymatic spectrophotometry method on automated analyzer.Results :The mean of age subjects was 56,98 ± 10,36 years old and 55,4% were male. Carbohydrate intake based on 24 hours food recall was 57,64 ± 10,85%. The median of LDH activity was 541,5 (164?6539) IU/L, 60,7% was increase.Conclusion :This study showed medium negative significant correlation (p = 0,017, r = - 0,317) between total carbohydrate intake per day in grams with LDH serum activity. If carbohydrate source is reduced, the LDH enzyme will increase to keep the glycolysis process going. The results of this study indicate that an adequate carbohydrate needed in patients with cancer.
Higher Nutritional Status of Lung Cancer Cachexia Patients is Associated with Higher Functional Capacity and Appetite Sunardi, Diana; Bardosono, Saptawati
World Nutrition Journal Vol 2, No 2 (2019)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (406.606 KB) | DOI: 10.25220/WNJ.V02.i2.0006

Abstract

Introduction: Lung cancer is highly prevalent and the major cause of cancer-related deaths worldwide.  Severity of weight loss has been shown to have a negative impact on patients? performance and quality of life.  Early detection of anorexia and decline of functional capacity will be very usefull to prevent severe weight loss and a better prognosis. Methods: A cross sectional study was conducted in Dharmais Cancer Hospital.  Subjects were lung cancer patients newly diagnosed or a minimal of 2 months pasca chemotherapy or radiotherapy, taken consecutively from inpatients and outpatients.  Results: Subjects eligible for the study were 47, with a composition of 55.3% men and 44.7% women in the age range from 36?79 years old. There were significant relationship between body weight and BMI with ECOG score. Body weight, BMI  and weight loss related significantly with VAS appetite and SNAQ score.  These result indicate that subjects with a higher BMI and a lower weight loss have a better physical performa and appetite.  There were significant relation between haemoglobin level, anemia status and serum albumin level with appetite and risk for anorexia. This result indicate that subjects with normal haemoglobin  and albumin have a good appetite and a lower risk for anorexia.  Conclusions: Positive prognosis of cancer patients can be obtained by maintaining BMI and preventing weight loss, since both affected the already known prognostic marker functional capacity significantly.  Serum Albumin and hemoglobin are not only simple test, but also brings benefits, a clinical marker that may be used to assess the risk of anorexia.
Correlation between Hair Zinc Level and Cognitive Function in Elderly Mutiara, Dian Sarah; Sunardi, Diana; Dewiasty, Esthika
World Nutrition Journal Vol 3, No 1 (2019): Volume 03 Issue 1 Include Supplements Oral Presentation Abstracts of 14th Sympos
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (212.875 KB) | DOI: 10.25220/WNJ.V03.i1.0007

Abstract

Background and Objectives : Neurodegenerative disease is the most problem in elderly. Amyloid ? (A?) accumulation is the major cause of cognitive impairment. Zinc has an important role in antioxidant and A? accumulation process. This study aimed to evaluate the correlation between hair zinc level and cognitive function in elderly.Methods : A cross sectional study was conducted involving 58 subjects of elderly in Jakarta. Subjects were recruited by consecutive sampling. Hair zinc level was measured by inductively coupled plasma emission spectrometer (ICPS) and cognitive function assessed by abbreviated mental test (AMT). Data analysis was done by spearman rank correlation test[DN1]  and p-value less than 0.05 was considered statistically significant.Results : The mean of age was 65.4 ± 4.4 years old and 56.9% of subjects were female. The mean of hair zinc level was 123.23 ± 69.71 µg/gram hair and 32.8% subjects had hair zinc deficiency. There was 91.4% subjects had normal cognitive function. The study showed no correlation between hair zinc level and cognitive function in elderly (p=0.871 ; r=-0.022).Conclusion : There was no correlation between hair zinc level and cognitive function in elderly. Further research is expected to be performed with different level of cognitive function.
Prediction of Post-operative Survival of Colorectal Cancer Patient By Using the Prognostic Nutritional Index: An Evidence-Based Case Report Manikam, Nurul Ratna; Kristian, Yosua Y; Lidwina, Luana; Sari, Ayu Diandra; Sunardi, Diana
World Nutrition Journal Vol 2, No 2 (2019)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.193 KB) | DOI: 10.25220/WNJ.V02.i2.0005

Abstract

Background: Colorectal cancer patients may be treated with several modalities and one of them is surgical treatment. Surgery in cancer patients is risky procedure and may not always resulted in prolonged survival. Therefore, before receiving any recommended treatment, the patient?s prognosis has to be assessed and defined properly. Several methods are available to assess the prognosis of cancer patients; one of them is the prognostic nutritional index (PNI).Objective: This study aimed to predict the survival of a colorectal cancer patient post-operatively by calculating the pre-operative PNI score.Method: Literature searching was done using inclusion and exclusion criteria on two databases, i.e. the PubMed and the Cochrane Library. The outcome was survival (disease-free survival, relapse-free survival, or overall survival).Results: Five articles that address the clinical question were retrieved. All indicated that a patient with low PNI score (<44.5) had a shorter overall survival (HR between 1.92 and 3.98 with all p values were <0.05).Conclusion: Pre-operative PNI score can be used to assess the overall survival of a colorectal cancer patient who underwent surgical resection. Patients with a PNI score > 44.5 had better survival than lower PNI score.
Associations of maternal body composition and nutritional intake with fat content of Indonesian mothers’ breast milk Kurniati, Ardesy Melizah; Sunardi, Diana; Sungkar, Ali; Bardosono, Saptawati; Kartinah, Neng Tine
Paediatrica Indonesiana Vol 56 No 5 (2016): September 2016
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1849.284 KB) | DOI: 10.14238/pi56.5.2016.297-303

Abstract

Background Breast milk is the best sole food for infants in their first six months of life. Breast milk fat content accounts for the largest part of infants’ energy and may be influenced by many factors, including maternal factors, which may vary in different settings. So far, there has been no published data about the breast milk fat content of Indonesian mothers, including whether it is affected by their body composition or nutritional intake.Objective To investigate breast milk fat content of Indonesian mothers and its associations with maternal body composition and nutritional intake. Method This cross-sectional study was conducted at Budi Kemuliaan Mothers’ and Children’s Hospital. Breast milk specimens were collected from 48 nursing mothers, centrifuged, and tested by creamatocrit for fat content. A 24-hour food recall was performed to evaluate maternal macronutrient intake. Maternal body composition was evaluated by bioelectric impedance analysis. Univariable correlations between breast milk fat content and either energy and macronutrient intake were assessed using the Spearman rho test.Results All nursing mothers had breast milk fat content within clinically normal range [mean 59.4 (SD 15.9) g/L]. There was no significant correlation between milk fat content and maternal body fat (r = -0.03, P=0.840), total body water (r = 0.09 P=0.509), or muscle mass (r = 0.08, P=0.577). Milk fat content seemed to weakly correlated with maternal fat intake, although it was not statistically significant (r = 0.27, P=0.065).Conclusion Breast milk fat content at one-month post delivery appears not associated with with maternal body composition. It seems to weakly correlate with maternal fat intake but findings need to be confirmed in larger studies with adjustment for confounding variables. 
Correlation between carbohydrate, protein and fat intake with serum c-reactive protein level in lung cancer patients stage IIIB-IV Amanda, Patricia; Sunardi, Diana; Sutandyo, Noorwati
World Nutrition Journal Vol 1, No 2 (2018)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (325.497 KB) | DOI: 10.25220/WNJ.V01i2.0006

Abstract

Introduction: The aim of the study is to determine the correlation between carbohydrate, fat and protein intake with the serum C-Reactive Protein level in lung cancer patients stage IIIB IV. The progression of lung cancer is influenced by immune system, genetic factors and inflammatory response, therefore CRP can be relied as one of the parameters for predicting cancer cell growth.Methods: The research with cross sectional design was conducted in Dharmais Cancer Hospital Jakarta. Subjects were recruited by consecutive sampling, 49 subjects with lung cancer stage IIIB- IV who currently not receving any treatment in Dharmais Hospital participating in this study A total of 49 subjects with lung cancer stage IIIB- IV who currently not receving any treatment were taken using consecutive sampling method. Results: The mean age of subject was 55,82 + 12,26 years old and 63,3% were male. The median value of CRP is 23,82 (0,30 - 207,29) mg/L.Conclusion: This study did not showed significant correlation between carbohydate, protein and fat intake with serum CRP level (p = 0,919; p = 0,257; p = 0,986, respectively). But on additional analysis we did found that there was a negative, non significant correlation between protein intake and serum CRP level in cancer patient stage IV, as well as fat intake and serum CRP level.