Andri Sukeksi
Analis Kesehatan Fakultas Keperawatan dan Kesehatan Universitas Muhammadiyah Semarang

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KADAR KOLESTEROL DARAH PADA PENDERITA OBESITAS DI KELURAHAN KORPRI SAMBIROTO SEMARANG

PROSIDING SEMINAR NASIONAL Vol 1, No 1 (2010): Bio Molekuler, Analis Kesehatan, Keperawatan
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Penderita obesitas mengalami penumpukan lemak yang berlebihan di dalam tubuh. Penyebab terjadinya obesitas biasanya disebabkan karena pola makan yang abnormal yaitu makan dalam jumlah sangat banyak dan makan di malam hari.. Penderita obesitas mengalami peningkatan kadar kolesterol dalam tubuh (Hiperkolesterolemia).  Tujuan dari penelitian adalah mengukur nilai Indeks Massa Tubuh (IMT) untuk menentukan kriteria obesitas, mengukur kadar kolesterol pada penderita obesitas dan mengetahui pengaruh obesitas terhadap kadar kolesterol. Jenis penelitian  adalah deskriptif , populasi penelitian adalah seluruh penderita obesitas di perumahan korpri Kelurahan Sambiroto Semarang. Sampel penelitian adalah  penderita obesitas di RW 8 Kelurahan sambiroto Semarang yang diambil secara total populasi. Jenis data yang dikumpulkan adalah data primer yang diperoleh langsung di lapangan dengan melakukan pemeriksaan kadar kolesterol darah. Hasil penelitian adalah dari sampel yang telah dilakukan pemeriksaan kadar kolesterol  didapat hasil  kadar kolesterol terendah 156,4 mg/dl, kadar kolesterol tertinggi 256,8 mg/dl, kadar kolesterol rata-rata 197,4 mg/dl. Dari hasil yang diperoleh berdasarkan Indeks Massa Tubuh (IMT) bahwa penderita obesitas tidak selalu kadar kolesterolnya tinggi. Karena kolesterol tidak selalu dipengaruhi oleh obesitas, tapi lebih dipengaruh pada konsumsi makanan yang mengandung kolesterol. Seperti mengkonsumsi daging, jerohan, dan telur yang dapat meningkatkan kenaikan kadar kolesterol dalam darah, karena di dalam makanan daging, jerohan, dan telur terdapat kandungan kolesterol yang cukup tinggi. Kata kunci : obesitas, kadar kolesterol

SURVEI PERILAKU PSN DAN SANITASI LINGKUNGAN PADA DESA ENDEMIK FILARIASIS DI KABUPATEN BLORA

JURNAL LITBANG Vol 4, No 3 (2006): Sain dan Teknologi
Publisher : JURNAL LITBANG

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Abstract

Background : Tke spread af filariasis disease can be control if the society lmow the procedure to avoid contact with infecler vector. Mosquite population as a infecter vector can be control by us with knowledge of fight the focus mosquite action. Mosquite control at the several area influenced by envirounment sqnitation, while lhe envirounment sanitation influenced by human action to manage it.Objective: To survey offight thefocus of mosquite action on society and observed the envirounment sanitation that corelated withfocus of mosquite plqce on Tawangrejo village on Blora.Method : population of this research is all of peoples on Tawangrejo village on Blora. Accidental sampling applied to take sample research. All of peoples that present in the healthy instruction as a sample research. To tqke the data of fight the focus mosquite used the questioner, while the observation done to observed the envirounment sanitation bydirect procedure on filariasis endemic village.Result : Among of 83,9 ok responden have offight thefocus mosquite action with baik predicqte. So on rotation of cukup and buruk is 1,7 96 and 14,4 %.Conclusion : Almost of all of the responden have of fight the focus mosquite action with baik predicate, so must befound the other caused ofspread offilariasis on Tawangrejo village.Key words : The fight of the focus of mosquite action, sanitation, filariasis

KADAR KOLESTEROL DARAH PADA PENDERITA OBESITAS DI KELURAHAN KORPRI SAMBIROTO SEMARANG

JURNAL KESEHATAN Vol 2, No 2 (2009): Ilmu-Ilmu Kesehatan
Publisher : JURNAL KESEHATAN

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Abstract

Abstract Patients with obesity have excessive fat accumulation in the body, causes the occurrence of obesity is usually caused by an abnormal eating pattern that is eaten in the number of very large and eat at night.. Obese People hove elevated levels of cholesterol in the body (hypercholesterolemia) (Mangku Sitepoe, l993). Cholesterol is a form of at that is naturally present in foods derived from animals, which allows the human body to make sex hormones and sexual function, adrenal hormones are necessary in the process of metabolism, and vitamin D. (lmam Suharto, 2004). Cholesterol is also useful for transporting fat in the blood throughout the body, which in a long time that blood vessels may be narrowed or closed. If the arteries (arteries) that provide blood to the hear, brain or organs - covered other important organs, can lead to risk of atherosclerosis, heart attack, stroke or failure of other vital organ functions. High levels of cholesterol called hypercholesterolemia is closely associated with the disease of obesity. (Corine T. Netzer, 1994). Based on the above background raised The question, "How can blood cholesterol levels in obese people in the housing KORPRI Sambiroto Semarang Kelurahan". The purpose of this study are: Measuring the value of Body Mass Index (BMD to determine the criteria for obesity, Measuring cholesterol in people with obesity. Knowing the influence of obesity on cholesterol levels Method: This type of research study is a descriptive The entire study population was obese in the housing KORPRI Sambiroto Semarang Kelurahan. Study sample was obese at 8 RW Semarang Kelurahan sambiroto taken in totol population. From the results of examination and discussion of research on the cholesterol wells in obese Semarang Kelurahan Simongan Ngemplak can be summarized as follows: From the samples that have been carried out Inspection lowest cholesterol 156.4 mg / dl, the highest cholesterol 256.8 mg / dl, cholesterol levels an Average of 197.4 mg / dl. From the results obtained based on Body Mass Index (BMI) that was not always obese, high cholesterol levels, because cholesterol is not always influenced by obesity, but more affected on the consumption of foods containing cholesterol. Like eating meat, jerohan, and eggs that can enhance the increase in blood cholesterol levels, because the meat in the diet, jerohan, and cholesterol content of eggs is high enough.   K keywords : obesity, cholesterol

KADAR KOLESTEROL DARAH PADA PENDERITA OBESITAS DI KELURAHAN KORPRI SAMBIROTO SEMARANG

PROSIDING SEMINAR NASIONAL 2010: PROSIDING SEMINAR NASIONAL HASIL-HASIL PENELITIAN
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Penderita obesitas mengalami penumpukan lemak yang berlebihan di dalam tubuh. Penyebab terjadinyaobesitas biasanya disebabkan karena pola makan yang abnormal yaitu makan dalam jumlah sangatbanyak dan makan di malam hari.. Penderita obesitas mengalami peningkatan kadar kolesterol dalamtubuh (Hiperkolesterolemia). Tujuan dari penelitian adalah mengukur nilai Indeks Massa Tubuh (IMT)untuk menentukan kriteria obesitas, mengukur kadar kolesterol pada penderita obesitas dan mengetahuipengaruh obesitas terhadap kadar kolesterol. Jenis penelitian adalah deskriptif , populasi penelitianadalah seluruh penderita obesitas di perumahan korpri Kelurahan Sambiroto Semarang. Sampelpenelitian adalah penderita obesitas di RW 8 Kelurahan sambiroto Semarang yang diambil secara totalpopulasi. Jenis data yang dikumpulkan adalah data primer yang diperoleh langsung di lapangan denganmelakukan pemeriksaan kadar kolesterol darah. Hasil penelitian adalah dari sampel yang telah dilakukanpemeriksaan kadar kolesterol didapat hasil kadar kolesterol terendah 156,4 mg/dl, kadar kolesteroltertinggi 256,8 mg/dl, kadar kolesterol rata-rata 197,4 mg/dl. Dari hasil yang diperoleh berdasarkanIndeks Massa Tubuh (IMT) bahwa penderita obesitas tidak selalu kadar kolesterolnya tinggi. Karenakolesterol tidak selalu dipengaruhi oleh obesitas, tapi lebih dipengaruh pada konsumsi makanan yangmengandung kolesterol. Seperti mengkonsumsi daging, jerohan, dan telur yang dapat meningkatkankenaikan kadar kolesterol dalam darah, karena di dalam makanan daging, jerohan, dan telur terdapatkandungan kolesterol yang cukup tinggi.Kata kunci : obesitas, kadar kolesterol

GAMBARAN PROFIL TOTAL POTEIN TERLARUT UNTUK MELIHAT HUBUNGAN KEKERABATAN Aedes sp. ISOLAT KENDAL

PROSIDING SEMINAR NASIONAL 2014: PROSIDING SEMINAR NASIONAL HASIL - HASIL PENELITIAN & PENGABDIAN
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Kasus ( DBD ) di Indonesia pertama kali dilaporkan pada tahun 1968 di Surabaya. Di JawaTengah terjadi 7.144 kasus sedangkan di Kabupaten Kendal masuk dalam 20 kota / kabupaten yang angka kematian akibat DBD sebesar > 2 %. Pada daerah endemis sering kali dilakukan program pemberantasan nyamuk terutama dengan fogging menggunakan berbagai insektisida yang berdampak pada resisitensi vektor, sedangkan pada daerah non endemis jarang / tidak pernah dilakukan program ini. Hasil kajian Analisis profil proteinya menunjukkan perbedaan pola pita pada masing – masing konsentrasi insektisida dan status resistensinya. Analisis profilprotein ini sangat penting dalam rangka menentukaan hubungan kekerabatan dalam satu strainmakluk hidup.  Tujuan penelitian ini adalah untuk visualisasi profil protein Aedes sp menggunakan SDS –PAGE dari berbagai daerah di kab. Kendal. Obyek penelitian adalah larva dan nyamuk Aedes spdari 3 wilayah di Kab.Kendal. Hasil penelitian menunjukkan pola pita antar profil protein terdapat variasi dalam jumlah dan ketebalan pita protein baik larva dan nyamuk. Pita protein spesifik muncul sebanyak 3 – 11dengan BM antara 250 – 15 kDa. Hasil ini memberikan gambaran bahwa pada satu spesies yangsama di wilayah tertentu terdapat variasi profil protein yang memungkinkan adanya keragaman hayati dalam mengungkap hubungan kekerabatan antar spesies tersebut. Kata Kunci : Aedes sp, Profil Total Protein, Kab. Kendal.

Ekstrak Air Daun Padi Memperbaiki Hematopoesis pada Tikus yang Terpajan Plumbum

Majalah Kedokteran Bandung Vol 47, No 2 (2015)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Plumbum (Pb) asetat menyebabkan gangguan hematopoesis melalui hambatan biosintesis heme dan defisiensi enzim G-6PD yang menimbulkan penurunan hemoglobin dan jumlah eritrosit, serta peningkatan sel retikulosit. Ekstrak daun padi mengandung protein metallothionein yang mengikat Pb. Tujuan penelitian adalah membuktikan ekstrak daun padi memperbaiki gangguan hematopoesis pada tikus terpajan Pb. Metode penelitian adalah randomized post test only control-group design, 28 tikus dibagi ke dalam 4 kelompok yaitu 1 kelompok kontrol dan 3 kelompok perlakuan. Kelompok kontrol dan perlakuan dipajan Pb 0,5 g/kgBB/hari dan kelompok perlakuan diberi ekstrak daun padi 0,2; 0,4; 0,8 setiap hari melalui sonde sampai minggu ke-8. Hari terakhir  minggu ke-8 diperiksa jumlah kadar Hb menggunakan cyanmethemoglobin dan jumlah eritrosit diukur menggunakan haematology analyzer, serta retikulosit menggunakan pengecatan BCB. Tempat penelitian dilaksanakan di LPPT UGM dan laboratorium biomedik UNIMUS Semarang, Maret–Mei 2014. Perbedaan antarkelompok untuk kadar Hb dan jumlah eritrosit dilakukan uji one way enzyme linked immunosorbent assays (ANOVA) dan Kruskal-Wallis untuk jumlah retikulosit. Hasil penelitian menunjukkan kadar Hb rata-rata mengalami kenaikan tidak bermakna (p=0.81), jumlah eritrosit rata-rata tidak ada perbedaan antara kelompok kontrol dan perlakuan (p=0,83), jumlah retikulosit rata-rata menurun bermakna dari kelompok kontrol sampai perlakuan (p=0,00). Simpulan, ekstrak daun padi mampu memperbaiki hematopoesis pada tikus terpajan Pb. [MKB. 2015;47(2):84–90]Kata kunci: Ekstrak daun padi, hematopoesis, pajanan Pb, tikusRice Leaf Water Extract Improves Hematopoiesis in Lead-Exposed Rats  Abstract Plumbum ( Pb ) acetate leads to hematopoiesis disruption by inhibiting heme biosynthesis and creating G-6PD enzyme deficiency, leading to decreased hemoglobin concentration and red cell count as well as  increased reticulocyte cells. Rice leaf extract contains metallothionein proteins that bind Pb. This study aimed to prove the ability of rice leaf extract wa to improve hematopoiesis disorder conditions in rats exposed to Pb. The method used was the randomized post-test only control group design. Twenty eight rats were divided into 4 groups: 1 control group and 3 treatment groups . In the control group and the treatments groups, the experimental rats were treated with 0.5 g/kg/day Pb. The treatment groups were treated by 0.2, 0.4, and 0.8 rice leaf extract, respectively, every day for 8 weeks. On the last day of the 8th week, blood samples were collected for Hb concentration measurements using cyanmethemoglobin and the erythrocytes and reticulocytes number were counted using a hematology analyzer and BCB, respectively. This study was conducted in LPPT UGM and Biomedicine UNIMUS in March–May 2014. The differences between groups in hemoglobin and erythrocyte parameters were tasted  using one way ANOVA while  Kruskal-Wallis test was used for the reticulocyte count. The results show that rice leaf extract treatment to rats exposed to Pb did not affect Hb (p=0.81) and erythrocytes count  (p=0.83), However, the mean reticulocyte count decreased significantly in Pb-exposed rats treated with rice leaf extract (p=0.00). In conclusion, rice leaf extract is able to improve hematopoiesis in rats exposed to Pb. [MKB. 2015;47(2):84–90]Key words: Hematopoiesis, Pb, rice leaf extract, rat DOI: 10.15395/mkb.v47n2.458

Aqueous IR Bagendit rice leaf extract decreases reticulocyte count in lead-exposed rats

Universa Medicina Vol 37, No 1 (2018)
Publisher : Faculty of Medicine, Trisakti University

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Abstract

BACKGROUNDLead acetate may inhibit the enzyme aminolevulinate dehydratase (ALAD) resulting in decreased heme synthesis (and consequently in anemia) but in increased number of reticulocyte cells. IR Bagendit paddy leaf water extract has a high metallothionein protein content which acts to bind to lead. The study objective was to determine whether aqueous IR Bagendit rice leaf extract dosage variations prior to lead exposure decreases reticulocyte count in lead-exposed rats. METHODSThe study was of randomized post test only control-group design involving a sample of 28 rats, that were randomized into 4 groups consisting of 1 control group and 3 treatment groups, daily administered with aqueous IR Bagendit rice leaf extract of respectively 0.2; 0.4; 0.8 mg using a feeding tube up to week 13. Lead exposure was also given using a feeding tube to both control and treatment groups at a dose of 0.5 g/kg BW/day, up to week 13. The reticulocyte count was then examined using supravital brilliant cresyl blue staining. The reticulocyte count was determined per 1000 erythrocytes and then converted into a percentage. Kruskal Wallis test followed with Bonferroni test was conducted to figure out the differences between groups. RESULTSMean reticulocyte count decreased significantly, starting from the control group up to the third treatment group (15.48 ± 3.41; 12.25 ± 03.28; 10.45 ±1.47; 9.10 ± 2.35 average per unit) (p=0.02). The Bonferroni test showed that the reticulocyte count was significantly decreased in the third treatment group (p=0.004). CONCLUSIONAqueous rice leaf extract significantly decreases reticulocytes in rats exposed to lead.

SURVEI PERILAKU PSN DAN SANITASI LINGKUNGAN PADA DESA ENDEMIK FILARIASIS DI KABUPATEN BLORA

JURNAL LITBANG Vol 4, No 3 (2006): Sain dan Teknologi
Publisher : JURNAL LITBANG

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Abstract

Background : Tke spread af filariasis disease can be control if the society lmow the procedure to avoid contact with infecler vector. Mosquite population as a infecter vector can be control by us with knowledge of fight the focus mosquite action. Mosquite control at the several area influenced by envirounment sqnitation, while lhe envirounment sanitation influenced by human action to manage it.Objective: To survey offight thefocus of mosquite action on society and observed the envirounment sanitation that corelated withfocus of mosquite plqce on Tawangrejo village on Blora.Method : population of this research is all of peoples on Tawangrejo village on Blora. Accidental sampling applied to take sample research. All of peoples that present in the healthy instruction as a sample research. To tqke the data of fight the focus mosquite used the questioner, while the observation done to observed the envirounment sanitation bydirect procedure on filariasis endemic village.Result : Among of 83,9 ok responden have offight thefocus mosquite action with baik predicqte. So on rotation of cukup and buruk is 1,7 96 and 14,4 %.Conclusion : Almost of all of the responden have of fight the focus mosquite action with baik predicate, so must befound the other caused ofspread offilariasis on Tawangrejo village.Key words : The fight of the focus of mosquite action, sanitation, filariasis

Ekstrak Air Daun Padi Memperbaiki Hematopoesis pada Tikus yang Terpajan Plumbum

Majalah Kedokteran Bandung Vol 47, No 2 (2015)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Plumbum (Pb) asetat menyebabkan gangguan hematopoesis melalui hambatan biosintesis heme dan defisiensi enzim G-6PD yang menimbulkan penurunan hemoglobin dan jumlah eritrosit, serta peningkatan sel retikulosit. Ekstrak daun padi mengandung protein metallothionein yang mengikat Pb. Tujuan penelitian adalah membuktikan ekstrak daun padi memperbaiki gangguan hematopoesis pada tikus terpajan Pb. Metode penelitian adalah randomized post test only control-group design, 28 tikus dibagi ke dalam 4 kelompok yaitu 1 kelompok kontrol dan 3 kelompok perlakuan. Kelompok kontrol dan perlakuan dipajan Pb 0,5 g/kgBB/hari dan kelompok perlakuan diberi ekstrak daun padi 0,2; 0,4; 0,8 setiap hari melalui sonde sampai minggu ke-8. Hari terakhir  minggu ke-8 diperiksa jumlah kadar Hb menggunakan cyanmethemoglobin dan jumlah eritrosit diukur menggunakan haematology analyzer, serta retikulosit menggunakan pengecatan BCB. Tempat penelitian dilaksanakan di LPPT UGM dan laboratorium biomedik UNIMUS Semarang, Maret–Mei 2014. Perbedaan antarkelompok untuk kadar Hb dan jumlah eritrosit dilakukan uji one way enzyme linked immunosorbent assays (ANOVA) dan Kruskal-Wallis untuk jumlah retikulosit. Hasil penelitian menunjukkan kadar Hb rata-rata mengalami kenaikan tidak bermakna (p=0.81), jumlah eritrosit rata-rata tidak ada perbedaan antara kelompok kontrol dan perlakuan (p=0,83), jumlah retikulosit rata-rata menurun bermakna dari kelompok kontrol sampai perlakuan (p=0,00). Simpulan, ekstrak daun padi mampu memperbaiki hematopoesis pada tikus terpajan Pb. [MKB. 2015;47(2):84–90]Kata kunci: Ekstrak daun padi, hematopoesis, pajanan Pb, tikusRice Leaf Water Extract Improves Hematopoiesis in Lead-Exposed Rats  Abstract Plumbum ( Pb ) acetate leads to hematopoiesis disruption by inhibiting heme biosynthesis and creating G-6PD enzyme deficiency, leading to decreased hemoglobin concentration and red cell count as well as  increased reticulocyte cells. Rice leaf extract contains metallothionein proteins that bind Pb. This study aimed to prove the ability of rice leaf extract wa to improve hematopoiesis disorder conditions in rats exposed to Pb. The method used was the randomized post-test only control group design. Twenty eight rats were divided into 4 groups: 1 control group and 3 treatment groups . In the control group and the treatments groups, the experimental rats were treated with 0.5 g/kg/day Pb. The treatment groups were treated by 0.2, 0.4, and 0.8 rice leaf extract, respectively, every day for 8 weeks. On the last day of the 8th week, blood samples were collected for Hb concentration measurements using cyanmethemoglobin and the erythrocytes and reticulocytes number were counted using a hematology analyzer and BCB, respectively. This study was conducted in LPPT UGM and Biomedicine UNIMUS in March–May 2014. The differences between groups in hemoglobin and erythrocyte parameters were tasted  using one way ANOVA while  Kruskal-Wallis test was used for the reticulocyte count. The results show that rice leaf extract treatment to rats exposed to Pb did not affect Hb (p=0.81) and erythrocytes count  (p=0.83), However, the mean reticulocyte count decreased significantly in Pb-exposed rats treated with rice leaf extract (p=0.00). In conclusion, rice leaf extract is able to improve hematopoiesis in rats exposed to Pb. [MKB. 2015;47(2):84–90]Key words: Hematopoiesis, Pb, rice leaf extract, rat DOI: 10.15395/mkb.v47n2.458